II Bio.Natural-Bioactive Natural Products Research Meeting

BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL

II Bio.Natural-Bioactive Natural II Bio.Natural-Bioactive Natural Products Research MeetingProducts Research MeetingNovember 18-19, 2021 | VirtualTime zone: Portugal Time (GMT)

Write us at: [email protected] | www.bionaturalconference.com

2021


About The ConferenceUnited Scientific Group in collaboration with CBIOS, the Research Center for Biosciences & Health Technologies at Universidade Lusófona proud to announce and warmly welcome you to the second edition of virtual conference on II Bio.Natural 2021 – Bioactive Natural Products Research, going to happen on November 18-19, 2021. The conference will offer a unique opportunity to share the latest updates, cutting-edge technological tools, and scientific advances in Natural Products research.

It will be a stupendous platform to present the latest advances in Natural Products research and to provoke new collaborations and exchange information on cutting-edge information on research & drug discovery.

Scientific SessionsThe conference is focused to deliver top notch scientific lectures in the fields discovery of natural products, natural products drug discovery, chemistry of natural products, marine natural products, functional foods. The subject areas may include, but are not limited to the following domains:

1. Natural Products in Drug Discovery

2. Natural Products Chemistry

3. Bioactivity of Natural Products

4. Marine Natural Products

5. Natural Cosmetics

6. Functional foods and food supplements

7. Other fields related to Natural Products

Reasons to Attend II Bio.Naturals-2021

Learn

II Bio.Natural 2021 is unique in its approach of encouraging a dialogue between speakers and delegates through its well-planned agenda with the series of talks, poster presentations, panel discussions and networking events that will keep participants engaged in learning.

Discover

The conference aims to provide timely, evidence-based information that helps allied experts from academic institutions, government agencies, societies, non-profit organizations and the industry towards natural products research and development.

Connect

II Bio.Natural 2021 connects life sciences and biomedical researchers from all over the globe to network and share cutting-edge research that leads to new break-throughs and career advancement. This meeting is focused to deliver top notch scientific lectures in the fields of natural products and drug discovery.

Previous Edition

I Bio.Natural virtual conference was held on 27-28 September 2019, and it was a great success! The conference has brought together speakers from leading institutes and organizations having a diverse subject expertise to deliver intensive and thought–provoking presentations.


Our Partners:

Publishing Partner

UNITED Scientific Group

A non-profit organization

United Scientific Group (USG) is a nonprofit organization with tax-exempt status under Section of Internal Revenue Code 501(c)(3) of the United States of America.

USG is led by a group of senior scientists as the board of directors, who are committed to work together and contribute their best services to the scientific community by supporting scientific meeting organization and open access content publication.

CBIOS, the Research Center for Biosciences & Health Technologies was created in 2011 as a R&D structure of COFAC / Universidade Lusófona to create and promote knowledge in the health sciences. As part of our vision, CBIOS develops Integrated Health Strategies aimed to support the progress of Lusophone societies.

Frontiers in Pharmacology is a leading journal in its field, publishing rigorously peer-reviewed research across disciplines, including basic and clinical pharmacology, medicinal chemistry, pharmacy, and toxicology. Field Chief Editor Heike Wulff at UC Davis is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians, and the public worldwide.

Lusófona University of Humanities and Technologies is the largest Portuguese private university, and the main institution of Grupo Lusófona, which administers other universities and colleges in Portugal, Brazil, Cape Verde, Angola, Guinea-Bissau and Mozambique.


08:45-09:00 Zoom Joining and AV Check

09:00-09:15 Welcome Address by: Luis Monteiro Rodrigues, CBIOS Director, Universidade Lusófona, Portugal Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal

Chairs: Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal Andreia Rosatella, Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal

Keynote Speakers

09:15-09:45 Keynote: Thomas Efferth, Johannes Gutenberg University, Germany Speaking on: Covid-19: Epidemiology, Pathophysiology, Therapy

09:45-10:15 Keynote: Raymond J. Andersen, The University of British Columbia, Canada Speaking on: Natural Product Drug Leads for Development of Host-Directed Therapies for Pandemics

10:15-10:45 Keynote: Deniz Tasdemir, GEOMAR Centre for Marine Biotechnology, Germany Speaking on: Marine Natural Product Research in the Omics Era

10:45-10:55 Break

Session I: Natural Products in Drug Discovery

Oral Talks

11:00-11:20 Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal Diterpenoids from Plectranthus spp. as a starting tool in Drug Development

11:20-11:40 Mattia Mori, University of Siena, Italy Selective Natural Product Modulators of DNA G-Quadruplex with Anticancer Potential

11:40-12:00 Daniela B B Trivella, Brazilian Biosciences National Laboratory, Brazil NP3 Platform: Assisting New Discoveries from Natural Products

12:00-12:20 Celia Cabral, University of Coimbra, Portugal Chemoprevention and Therapeutic Role of Phytochemicals in Glioblastoma

12:20-12:40 Mariana Almeida, Lab. Medinfar-prod. Farmacêuticos Sa, Portugal Natural ingredients: Innovation in food supplements

12:40-13:00 Christopher N. Boddy, University of Ottawa, Canada Armeniaspirols, A New Class of Gram-Positive Antibiotics that Target Clp Proteases

13:00-13:20 Daniele Passarella, Università degli Studi di Milano, Italy Cannabidiol: intriguing target and creative building block

13:20-13:40 Maha Abdallah, Instituto de Biologia Experimental e TecnolÃ³gica, Portugal Evaluation of Extracts Obtained from Marine By-products using Natural Eutectic Solvent Systems for their Therapeutic Application in the Dry Eye Disease

13:40-14:15 Lunch

THURSDAY NOVEMBER 18, 2021DAY-01


14:15-14:35 Sónia Aguiar da Rocha, University of Porto, Portugal Optimization of in vitro Experimental Conditions for Glycogen Phosphorylase Inhibition Assay and Demonstration of High Inhibitory Effectiveness by Chromone Derivatives

14:35-14:55 Learn-Han Lee, Monash University Malaysia, Malaysia Promising Novel Anti-MRSA Protein Derived from Novel Streptomyces Strain Isolated from Malaysia’s Mangrove Forest

14:55-15:15 Bruno Botta, Sapienza University, Italy Challenging Organic Synthesis Inspired by Nature: From Natural Products Chemistry to Drug Discovery

15:15-15:35 Ru Angelie Edrada-Ebel, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of

Strathclyde, UK Using Concatenated NMR and MS Analytical Data for Metabolomic-guided Production and Isolation of Bioactive Natural Products

15:35-15:55 Tanja Grkovic, National Cancer Institute, NIH, USA Generation of Natural Product Libraries for High Throughput Screening

15:55-16:15 Jan Borlinghaus, RWTH-Aachen University, Germany Allicin from Garlic Inhibits DNA Gyrase Activity in Bacteria

16:15-16:35 Daniel dos Santos, CBIOS-Universidade Lusófona Research Center for Biosciences & Health Technologies,

Lisbon, Portugal ABC Transporters: From Multidrug Resistance to Cystic Fibrosis

16:35-16:55 Jaclyn Winter, University of Utah, United States Harnessing the Chemical Potential of Unprecedented Microbes from the

16:55-17:15 Kumarappan Chidambaram, King Khalid University, Saudi Arabia Ziziphus mauritiana Lam Attenuates Airway Inflammation via Downregulating NFκB Pathway in Both in-vitro & in-vivo Models of Asthma

17:15-17:30 Break

Poster Presentations

17:30-17:40 P-01: Jessica Karina Díaz Cantón, Instituto de Química, UNAM, México Evaluation of the Antidepressant Effect and Possible Mechanism of Action of the Essential Oil of Litsea Glaucescens (Kunth) (Mexican laurel) Administered by Inhalation

17:40-17:50 P-02: Carlos Fernández Galleguillos, Universidad Austral de Chile, Instituto de Farmacia, Chile Alkaloid Fingerprinting, Antiproliferative and Cholinesterase Inhibition Potential of Rhodophiala Advena Bulbs

17:50-18:00 P-03: Eva María Domínguez-Martín, CBIOS – Universidade Lusófona’s

Research Center for Biosciences & Health Technologies, Portuga Phytochemical Study and Anti-glioblastoma Activity Evaluation of Plectranthus Hadiensis (Forssk.) Schweinf. Ex Sprenger Var. Hadiensis

18:00-18:10 P-04: Merilin Al Sharif, Institute of Biophysics and Biomedical Engineering, Bulgarian

Academy of Sciences, Sofia, Bulgaria New Potential Pharmacological Targets of a Plant-derived Hydroxyanthraquinone from Rubia Cordifolia L.

18:10-18:20 P-05: Rita Almeida, Chinese Academy of Sciences, Shanghai, China Mining the Chemodiversity of Diterpenoids in Scutellaria Baicalensis


09:00-09:10 Zoom Joining and AV Check

09:10-09:15 Welcome Address by: Luis Monteiro Rodrigues, CBIOS Director, Universidade Lusófona, Portugal Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal

Chairs: Mattia Mori, University of Siena, Italy Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal

Session II: Marine Natural Products

Oral Talk

09:15-09:35 Fabians Faisal Dinelsa, IPB University, Indonesia Oxy-Polybrominated Diphenyl Ethers from the Indonesian Marine Sponge Lamellodysidea Herbacea: Isolation, Reaction, Computational Study, and SAR


09:35-09:45 P-06: Alejandra Yoselin González-Muñiz, Iinstituto Nacional De Neurología y Neurocirugía Manuel

Velasco Suárez (INNNMVS), México Antineoplastic Extracts from the Giant Deep-sea Worm Riftia Pachyptila on Glioblastoma Cells

09:45-09:55 P-07: Saif Aldeen Jaber, University of Strathclyde, United Kingdom Implementing Metabolomic Tools for the Isolation of Anti-biofilm Metabolites from Endophytic Dendryphiella Salina Isolated from Scottish Marine Laminaria Hyperborea

Session III: Natural Cosmetics

Oral Talk

09:55-10:15 Duha Alamoudi, University college London (UCL), United Kingdome Trends in Nanotechnology for Skin Anti-Aging Strategies and the Formulation of Bakuchiol in a Novel Nanocarrier


10:15-10:25 P-08: Cíntia Almeida, CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health

Technologies, Portugal Using Lipids Extracted from Black Soldier Fly Larvae for Nanoparticles Development - Preliminary Studies

10:25-10:35 P-09: Ines Calamote, Universidade Lusófona de Humanidades e Tecnologias, Portugal Innovative Formulations Loading Phytochemicals to Tackle Skin Ageing: Preliminary Studies

Session IV: Natural Products Chemistry

Oral Talks

10:35-10:55 Chi Godloves Fru, University of Buea, Cameroon Saponins from Raphia Vinifera Fruit and their Cytotoxic Activity

10:55-11:15 Fernando Reyes, Fundación MEDINA, Spain Structural Elucidation of Complex Microbial Natural Peptides Aided by Biosynthetic Gene Cluster Analysis

FRIDAY NOVEMBER 19, 2021DAY-02


11:15-11:35 Frank Hahn, University of Bayreuth, Germany Exploiting the Biosynthetic Pathways of Antifungal Polyketides as a Source for Novel Chemoenzymatic Tools

11:35-11:55 Diana Pinto, University of Aveiro, Portugal Can Underexplored or Medicinal Species be Exciting Ingredients in the Formulation of Smart Foods or Natural Medicines?

11:55-12:15 Helena Mannochio Russo, Institute of Chemistry, Sao Paulo State University, Brazil Use of Statistical Tools to Accelerate the Natural Products Workflow – A Malpighiaceae Case Study

12:15-12:35 Anjar Purba Asmara, University of Technology Sydney, Australia Antioxidant and α-glucosidase Inhibitory Activities of Acacia Saligna Extracts

12:35-13:00 Lunch

Chairs: Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal Ana Mourato, University of Lisbon, Portugal


13:00-13:10 P-10: Vera M.S. Isca, Universidade Lusófona de Humanidades e Tecnologias, Lisboa, Portugal New Hit Ester Derivatives to Target Protein Kinase C Isoforms using A Natural Diterpenoid

13:10-13:20 P-11: Epole Ntungwe, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health

Technologies, Portugal Self-assembly Nanoparticles of Three Abietane Diterpenes from Plectranthus Species

13:20-13:30 P-12: Ana C. Zanatta, São Paulo State University (Unesp), Institute of Chemistry, Brazil Multivariate Statistical Analysis to Evaluate the Effects of Environmental Factors on the Chemical Profile of Serjania Marginata Casar. Leaves

13:30-13:40 P-13: Izabela Grzegorczyk-Karolak, Medical University of Lodz, Poland Production of Bioactive Polyphenols in Salvia Viridis Shoots Cultivated in Temporary Immersion System

13:40-13:50 P-14: Skała Ewa, Medical University of Lodz, Poland Production of the Essential Oil by Codonopsis Pilosula (Franch.) Nannf. Transformed Roots

Oral Talks

13:50-14:10 Andrea A Stierle, University of Montana, MT, USA Elicitation of Cryptic Biosynthesis in the Search for New Antibiotics from Extremophilic Fungi

14:10-14:30 Jakob Magolan, McMaster University, Canada Chemical Synthesis of Prenylated Phenolic Natural Products

Session V: Other Fields Related to Natural Products


14:30-14:40 P-15: Fatema Aljishi, UCL School of Pharmacy, London, United Kingdom Morinda Perspective use in the Treatment of Skin Conditions: A Review

14:40-14:50 P-16: Ana Júlio, CBIOS-Research Center for Biosciences & Health Technologies, Lusófona University, Portugal The Role of Bioderived Ionic Liquids in Topical Formulations Containing Hydroxycinnamic Acids

14:50-15:00 P-17: Lukasz Kuzma, Medical University of Łódź, Poland Biomass Accumulation and Phenolic Acid Biosynthesis in Salvia Austriaca Jacq. Hairy Root Culture Grown in Erlenmeyer Flasks and in Temporary Immersion Bioreactor RITA®


15:00-15:10 P-18: Henoc del Rosario García, Instituto Universitario de Investigaciones Biomédicas y Sanitarias, Spain Structure-activity Relationships Reveal a 2’-furoyloxychalcone as a Potent Cytotoxic and Apoptosis Inducer in Human U-937 Leukaemia Cells

15:10-15:20 P-19: Carolina P. Reyes, Universidad de La Laguna, Spain Canarian Cyanobacterias as a Potential source of Fungicide Natural Products

15:20-15:30 Break

VI: Bioactivity of Natural Products

Oral Talk

15:30-15:50 Claudio Ferrante, Università degli Studi “Gabriele d’Annunzio”, Italy Comparative Investigation of Composition, Antifungal, and AntiInflammatory Effects of the Essential Oil from Three Industrial Hemp Varieties from Italian Cultivation

15:50-16:10 Tobias A. M. Gulder, Technical University of Dresden, Germany Biosynthetic Enzymes as Tools for Natural Product Synthesis in Vivo and in Vitro


16:10-16:20 P-20: Przemysław Sitarek, University of Lodz,Poland Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained through Rhizobium rhizogenes-Mediated Transformation

16:20-16:30 P-21: Dana Atoum, University of Strathclyde, United Kingdom Use of Multivariable Data Analysis Comparison For Unravelling the Anticancer and Antioxidant Differences Between Two Endemic Varieties of Chamomile

16:30-16:40 P-22: Ebtihal Althomaly, University College London, United Kingdom How Effective are Natural Products at Improving Muscle Strength and Function in Older Adults?

16:40-16:50 P-23: Ester Gloria Saavedra Díaz, Universidad de Las Palmas de Gran Canaria, Spain Natural Occurring Chlorinated Guaianolide Linichlorin a Induces Apoptosis Dependent on Reactive Oxygen Species Generation in Human U-937 Leukaemia Cells

16:50-17:00 P-24: Sandra Ferreira, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies,

Portugal Evaluation of the Lysyl Oxidase Like 2 (Loxl2) Inhibitory Activity of a Natural Pimarane and its Sugar Derivatives

17:00-17:10 P-25: Gabrielle Bangay, Universidade Lusófona de Humanidades e Tecnologias, Portugal Royleanone Diterpenoids from Plectranthus spp. as P-glycoprotein Inhibitors

17:10-17:20 P-26: Sofia Ferreira, Universidade Lusófona de Humanidades e Tecnologias, Portugal Urolithin B hinders IAPP Aggregation: A Potential Role of Diet-derived Metabolites towards Diabetes Management

17:20-17:30 P-27: Márcia Filipe, CBIOS – Center Research for Biosciences & Health Technologies, Lisbon, Portugal Medicinal Centauri Honey: Chemical Composition and Antioxidant Properties

17:30-17:40 P-28: Márcia Santos Filipe, CBIOS – Center Research for Biosciences & Health Technologies, Lisbon, Portugal Novel Masks Impregnated with Antioxidant Essential Oils

17:40-17:50 P-29: Iris Guerreiro, CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health Technologies,

Portugal Plant Polyphenols and Renal Heath: The Relevance of Bioavailability


Session VII: Functional Foods and Food Supplements

Oral Talk

17:50-18:10 Xinglin jiang, Technical University of Denmark, Kongens Lyngby, Denmark Distribution of Poly-L-Lysine Synthetases in Coryneform Bacteria Isolated from Cheese and Human Skin

Poster Presentation

18:10-18:20 P-30: Marisa Nicolai, CBIOS-Universidade Lusófona de Humanidades e Tecnologias, Portugal Phenolic Compounds in Portuguese Grape Pomace Flour

18:20-18:30 P-31: Bruno Gonçalves, Research Institute for Medicines (iMed.ULisboa), Universidade de Lisboa, Portugal Molecular Dynamics Study of the ABCG2 Structural Changes induced by ATP and Substrate Binding

18:30-18:40 Concluding Remarks by the Chair

For More Information: https://bionaturalconference.com/

# 8105, Suite 112, Rasor Blvd, Plano, TX 75024, USA

Ph: +1-408-426-4832/33; Toll Free: +1-844-395-4102; Fax: +1-408-426-4869

Email: [email protected]

Web: https://bionaturalconference.com/

UNITED Scientific Group

A non-profit organization

Documents

II Bio.Natural-Bioactive Natural Products Research Meeting