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SCIENCE, VOL. 135

correctly that these bursts of REMs, asthey are called, meant that the sleep-ing person was dreaming. The first ob-jective indicator of dreaming had beendiscovered. In the 10 years since thathistoric observation, the scientific studyof dreams has begun to flourish inlaboratories all over the world.

Edwin Diamond, a general editor ofNewsweek and formerly its scienceeditor, has written a highly readableand accurate account of this new sci-ence of dreams. Diamond, good report-er that he is, conveys to the reader theextraordinary drama and human inter-est of this discovery and its considera-ble consequences. But that is by nomeans all that is in this lively book.There is an incredible chapter in whichFreud is bracketed with the IroquoisIndians and a lot of other fresh materialthat I have not seen in other books ondreams.

This is a book not only for scientiststo recommend to their nonscientificfriends but one which they themselvescan read with enjoyment and profit.Considering the rate at which new in-formation about dreams is accumulat-ing, Diamond will have to revise hisbook every few years to keep it up todate.

CALVIN HALLInstitute of Dream Research,Coral Gables, Florida

General Biology Textbooks

Biology. Its principles and implications.Garrett Hardin. Freeman, San Fran-cisco, Calif., 1961. xi + 682 pp.Illus. $8.

Biology. An introduction to the scienceof life. C. J. Goodnight, M. L. Good-night, and R. R. Armacost. Wiley,New York, 1962. vii + 460 pp. Illus.$6.95.

The revitalization of high schoolbiology teaching, now occurring as aresult of the versions of BSCS HighSchool Biology courses developed bythe American Institute of Biological Sci-ences' Biological Sciences CurriculumStudy, has exciting implications for theteaching of biology in colleges. Neitherof the college texts reviewed here waswritten in anticipation of this happysituation, but Hardin's Biology shouldnevertheless make a distinguished con-tribution of its own to liberal educa-tion. It is a thoughtful, broadly con-

1058

ceived, and thoroughly modern presen-tation of biological science. The textis divided into four parts: Part 1 isconcerned with general principles. Hereare introduced in lucid prose, withimaginative models and clear illustra-tions, the concepts of cellular biology,cybernetics, and evolutionary mecha-nisms which are then interlaced through-out the remaining parts of the bookto provide an unusually well-integratedtreatment of these subjects. Part 2 dealswith plants, and emphasis here is onfunctional interpretation of structure.Discussions of ecology, energy cycles,and evolution are appropriately and ef-fectively integrated with the generalmaterial of this section.

Fifteen of the 37 chapters are de-voted to part 3, on animal biology, inwhich there is a review of the majorphyla with extensive discussion of physi-ology, primarily human. Part 4 presentsa balanced modern treatment of hered-ity. In addition to a 17-page index,there is a glossary and 12 short ap-pendices consisting primarily of tablesof quantitative data and mathematicalformulas. A teacher's manual is alsoprovided.

This is a biology text with very fewpeers. Perhaps its outstanding charac-teristic is the accessibility of its informa-tion to the student. This derives froma number of qualities, not the least ofwhich is Hardin's superior style ofwriting, and includes the careful at-tention he pays to the human impli-cations of the subject. Most appealingto the clasroom teacher, however, ishis extensive use of the historical meth-od. Following the "path of discovery,"as Hardin calls it, not only providesinsights into the attitudes of scientists atwork but also creates the atmospherefor understanding and appreciating thenature of scientific "truths" and theways in which these are discoveredand stated. Other features are (i) thearrangement of the text which allowsflexible use; (ii) the end-of-the-chapterquestions and problems which areworthy of the name; (iii) on-the-spotderivations of new terms from theirGreek and Latin roots (greatly to beencouraged); and (iv) the deep im-pression, made continuously through-out the book, that biology is an intel-lectually exciting and rewarding study.

Biology by Goodnight, Goodnight,and Armacost is also divided into foursections. The first section is concernedwith defining science, protoplasm, andthe cell; the second section, six chapters,

describes animal structure and physi-ology, primarily human; in the suc-

ceeding four chapters the structure andfunction of higher plants are considered,and the plant kingdom is surveyed,while the last four chapters are devotedto genetics, evolution, ecology, andconservation. The text is written inclear, short sentences, and it is wellillustrated with numerous line draw-ings and photographs. There is a 16-page index, an appendix containingtables of classification, and a glossary(no word derivations, however).

CHARLES S. THORNTONDepartment of Biology, Kenyon College

New Books

Biological and Medical Sciences

American Drug Index, 1962. Charles 0.Wilson and Tony E. Jones. Lippincott,Philadelphia, Pa., 1962. 846 pp. $6.75.

Aspects of Medical Investigation inAfrica. Charles Wilcocks. Oxford Univ.Press, New York, 1962. 133 pp. 18s.

Biological Alkylating Agents. W. C. J.Ross. Butterworth, Washington, D.C.,1962. 242 pp. Illus. $10.50.

Biological Effects of Freezing and Super-cooling. A. U. Smith. Williams and Wil-kins, Baltimore, Md., 1961. 472 pp. Illus.$11.Chemotherapie und Prophylaxe des

Krebses. H. von Euler. Thieme, Stuttgart,Germany, 1962. 152 pp. Illus. DM. 25.The Enzymes of Lipid Metabolism. P.

Desnuelle, Ed. Pergamon, New York,1961. 324 pp. Illus. $10. Proceedings ofthe Sixth International Conference on theBiochemistry of Lipids, held at Marseillesin 1960. The papers are in English andFrench.

Morphogenesis of the Vertebrates. The-odore W. Torrey. Wiley, New York, 1962.610 pp. Illus. $9.95.

Physiology of Strength. I'heodor Het-tinger. Thomas, Springfield, Ill., 1961. 98pp. Illus. $4.50.

Problems in Communication. CharlesWatkins and Benjamin Pasamanick, Eds.American Psychiatric Assoc., Washington,D.C., 1961. 131 pp.

Rudolf Virchow Medical Society in theCity of New York. Proceedings, vol. 19.Hans E. Bejach, Hans Lehfeldt, GeorgeSchreiber, Eds. Karger, New York, 1961(order from Albert J. Phiebig, WhitePlains, N.Y.). 245 pp. Illus. Paper, $8.50.The Seeing Eye. H. Asher. Duckworth,

London, 1962. 278 pp. Illus. 30s.A Survey of Cardiac Glycosides and

Genins. J. Hampton Hoch. Univ. of SouthCarolina Press, Columbia, 1961. 94 pp.(tables).

Soil Management for Conservation andProduction. R. L. Cook. Wiley, New York,1962. 539 pp. Illus. $9.95.The Structure and Biosynthesis of Mac-

romolecules. D. J. Bell and J. K. Grant,Eds. Cambridge Univ. Press, New York,1962. 132 pp. Illus. $5.50.

SCIENCE, VOL. 135

California Institute of Technology: Case Institute of Technology: University of Chicago: Columbia University

Massachusetts Institute of Technology: University of Michigan: Pennsylvania State University: Stanford University: Tulane University

Science and DefenseIn these times Science cannot live in an undefended atmosphere. And Defense, without Science would be no de-fense at all.:: The scientific community of the nation wants to apply its talents to the problems of defense. TheDepartment of Defense needs the best possible technical inputs to resolve the questions and reach the de-cisions which determine our defense posture.:: At the behest of the government, nine great universities havejoined to sponsor a non-profit association, called the Institute for Defense Analyses, to provide an importantlink between the two separate but interdependent specialties.:: IDA iS staffed by scientists and engineers broughtfrom all sources of such talents-from acad6mic pursuits, from professional practice, from the research anddevelopment agencies of industry, from experimental laboratories, from graduate circles.:: IDA accepts, andcan put to good use on its permanent professional staff, practitioners of almost all the scientific disciplines. Theyfind real satisfaction in being identified with work at the interface between science and strategy, one of the mostimportant relationships of our times.:: Due to its unique nature and to the two-way purpose of its basicstructure, IDA also can accept people for comparatively short periods of time. A two- or three-year stint withIDA could be the catalytic agent in your career. Possibly it could satisfy that feeling that you owe part of your-self to your country. Probably it would show you new facets of, and new uses for, the discipline you profess.Why not get in touch with us?

INSTITUTE FOR DEFENSE ANALYSES Department B, I 7 I O H Street, NW,Washington 6, DC An equal opportunity employer

23 MARCH 1962 1073

HENW BOOKSMarch 1962

Response of the Nervous System toIonizing RadiationProceedings of an International Symposium, Sep-tember 1960, held at Northwestern UniversityMedical School

Edited by THOMAS J. HALEY andRAY S. SNIDER

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Comparative NeuropathologyBy J. R. M. INNES anid

L. Z. SAUNDERS839 pp.. $32.00

Biological Transmission of DiseaseAgentsA Symposium held under the auspices of theEntomological Society of America, Atlantic City,December 1960

Edited by KARL MARAMOROSCH192 pp., $7.00

Tumors Induced by Viruses:Ultrastructural Studies

Edited by A. J. DALTON anzdFRANCOISF HAGUENAUJ

229 pp., $9.50Comparative Biochemistry

Edited by M. FLORKIN andH. S. MASON

Volume 3, Constituents of Life, Part A959 pp., $30.00

Subscription price $27.00Subscription price valid on orders for thecomplete set received before publication ofthe last volume

Biochemical Applications of GasChromatography

By H. P. BURCHFIELD anidE. E. STORRS

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Methods in Carbohydrate ChemistryEdited by R. L. WHISTLER anzd

M. L. WOLFROMAsristant Editor: JAMES N. BEMILLERVolume 1, 589 pp., $20.00

Introductory Organic QuantumChemistry

By G. KARAGOUNISTranslated from the German by

F. C. NACHOD204 pp., $6.50

Catalysis by MetalsBy G. C. BOND

532 pp., $15.50

Air PollutionA Comprehensive TreatiseComplete in 2 volumesEdited by A. C. STERNVolume 2, 586 pp., $18.50

ShockPathogenesis and TherapyAn International Symposium held in Stockholm,June 1961

Edited by K. D. BOCKabout 390 pp.. $13.00

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LettersDeferring to a Minority

Your news note on the U.N. "popu-lation explosion" debate [Science 135,29 (5 Jan. 1962)] has, if I read it cor-rectly, some disturbing implicationsthat may have escaped many readers.The implication is clear that the

government of the United States isdeferring, on a matter of transcendentinternational importance, to politicalpressure by a religious minority. Youwould also seem to suggest that whilethe U.S. government is sufficiently con-cerned with the welfare of the UnitedNations to avoid "arousing furtherantipathy to that troubled organiza-tion," it is convinced that the minoritygroup would not sufficiently share suchconcern to refrain from action thatwould generate antipathy.The exercise o'f the veto power by

this particular church is not new toanyone familiar with the human popu-

lation problem. It is significant, how-ever, that this should be recognized inthe pages of Science.

This is a matter where time is of theessence, since, with even the full sup-port of the United Nations and theU.S. government, progress in reducingpopulation growth is sure to be slow,initially at least. Meanwhile 100 millionbabies a year are born, many of themforeordained to die miserable and pain-ful deaths. Those who live will oftenlive at the expense of those born earlier.

WILLIAM VOGT

140 Riverside Drive, New York

Allowance for Overhead

The editorial entitled "Costly cash"[Science 134, 2009 (1961)] does notgive a completely accurate picture withrespect to overhead charges on gov-

ernment-supported research contractsand grants. While it is true that Na-tional Science Foundation grants giveonly 20 percent, this 20 percent isapplicable to all charges, including ap-

paratus, supplies, and so on. The largeroverhead allowances in grants fromother agencies are usually applied onlyto direct salary charges. Thus, theNational Science Foundation's 20 per-cent might be equivalent to Office ofNaval Research overhead allowancesof 40 percent. Furthermore, some

agencies stipulate that there must be

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a university contribution to the totalresearch cost of a project, the amountvarying from perhaps 5 to 50 percent.There is also the consideration that,at the termination of the contract orgrant, the title to capital equipmentrests either with the government orwith the university. Thus, it wouldseem that we have to look beyond thepercentage figure in order to obtain arealistic evaluation of overhead allow-ances.

LEONARD MULDAWERTemple University,Philadelphia, Pennsylvania

I have read with considerable in-terest the editorial entitled "Costlycash." For your information, during1960-61, Western Reserve University,while spending $5.0 18 million in fed-eral and private funds for project re-search, incurred an obligation for un-reimbursed indirect costs of $665,000.I should like to point out that whilegrants, particularly those from the U.S.Public Health Service, do not providefor anything like sufficient overhead,many nonfederal sources are even lessgenerous. Thus it seems to me that wemust not level such charges against thefederal government alone.On the basis of a formula worked

out by the government audit agencywe have determined that 26.2 percentof the total costs is an allowablecharge for indirect costs on researchprojects. While we have not, to date,turned down any grant because of in-adequate allowance for overhead, thereis little doubt in my mind that thispossibility will become increasinglyless remote in the years ahead.

WILLIAM M. HESTONWestern Reserve University,Cleveland, Ohio

The Rise of Sap

In the article "Cohesive lift of sapin the rattan vine" [Science 134, 1835(1961)], Scholander, Hemmingsen, andGarvey state that the rise of sap intall trees has been puzzling "for morethan a century" and that the cohesiontheory of Dixon and Joly (1894) andAskenasy (1895) is generally accepted.

This very problem was consideredby the reverend Stephen Hales (1677-1761 ) in the early years of the 18thcentury. Hales, known as the first manto have measured arterial blood pres-sure [Haemostatics (1733)], was inter-

23 MARCH 1962

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1076 SCIENCE, VOL. 135

I

ested in the quantitative approach tovarious problems of animal and plantphysiology. As far as I know, he asso-ciated the rise of sap in tall trees withthe pulling force generated by evapora-tion from the leaves. Does not Hales'sprinciple underlie Dixon and Joly's aswell as Askenasy's theory?

Almost a quarter of a millenniumhas passed since Hales attacked theproblem which, as Scholander says,still challenges "the experimental in-genuity of future workers." It is worthwhile to remember that, according toHales, our thoughts should carry us"a little farther than the plain evi-dence of experiments will warrant . . .

otherwise we should make but veryslow advances in future discoveries."Is it experimental ingenuity or in-genuity in conceptualization which nowis needed most?

SIGISMUND PELLER164 East 81 Street, New York

Objectivity and Responsibility

I enjoyed and appreciated the edi-torial "The other fellows' ball park"[Science 134, 1163 (20 Oct. 1961)].This touches one facet of a broaderproblem. I observe regretfully that cer-tain elements of the scientific com-munity are so absorbed in presentingthe unprejudiced, objective viewpointthat they often do great damage tothe democratic cause, usually by care-less implication and omission. This isusually attributable to their being farbetter informed about the weaknessesof our own system than they are aboutthe weaknesses of the competitive sys-tem.Of late, Science has been particu-

larly negligent about accepting re-sponsibility for presenting a completepicture. For instance, in "Soviet de-fections: Conclusions of broad discon-tent unwarranted" ("Science and thenews," 20 Oct.), the last paragraphis expressed exactly as I would expectit to be stated in a Russian newspaper,and no doubt Russian newspapers willquote this material verbatim.

Science and scientists cannot divestthemselves of their national responsi-bility to consider the net effect of theirexpressions, particularly at this timewhen our own citizens and people theworld over are keenly aware of the roleof science in the present and future.

WILLIAM E. N. DOTY1507 Holbrook, Ponca City, Oklahoma

MeetingsMicrobiology in Latin America

The second Latin-American and thefirst Costa Rican national congresses ofmicrobiology were jointly held from10 to 17 December 1961, in San Jose,Costa Rica. The meeting was attendedby about 300 participants from 16 na-

tions, including 50 from England, Cana-da, and the United States.

Listed in the scientific program were

more than 150 titles, encompassing thefollowing fields: general, medical, andveterinary bacteriology; immunology;helminthology; mycology; protozoology;virology; phytopathology; and agricul-tural and industrial microbiology. Thegreatest interest was expressed in medi-cal microbiology. Abstracts of paperswere published in a "General programand resume"; many of the individualpapers will appear in scientific journals.

Special symposia or panel sessionsfocused on leishmaniasis, intestinalparasitosis, microbial physiology and

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23 MARCH 1962 1077

biochemlistry, and the teaching of micro-biology and parasitology. In other ses-

sions, new and imlportant scientific filmsavailable for educational purposes were

shown. SimultanCous Spanish-Englishtranslation made language no barrierto effective commlaunication in the spe-

cial sessions.

Registrants were afforded opportuni-ty to inspect the entirely new and re-

niarkably designed buildings compris-ing the University of Costa Rica. Thestatus of microbiology in the host na-

tion was indicated by its position as a

separate college and by an impressivelyfunctional and well-equipped building inUniversity City. A day was devoted toa trip through beautiful mountainouscountryside to the Inter-American In-stitute of Agricultural Science.

Anmong the commnercial and scientificexhibits at the congress, that of Re-vista Latinamnericana de Microbiologia,an international journal of the Latin-American Association, elicited specialinterest. The journal provides lucid ab-stracts in translation of the articles,which are usually in Spanish. Important

Attachments available for Bausch & Lomodel "N" cameras, Leitz Ibso & MakBeamsplitters

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for coverage of microbiology in a greatgeographical area Revista is available at$6 (U.S.) per year through the ed-itor, J. M. Gutierrez Vasquez, EscuelaNacional de Ciencias Biologicas, In-stituto Politecnico Nacional, Mexico,D.F.A fine social program included daily

luncheons, staging of traditional musicand dance, an orchestral symphony, anda grand ball in the Latin-Americanmanner, at which congress participantswere honored by the presence of thePresident of the Republic, Senior MarioEchandi Jimenez.

The congress was ably managed byan organizing committee of the CostaRica Association, of which the secre-tary-general was John L. de Abate, atthe time of the meetings. Officers ofthe Latin-American Association wereGeraldo Varela, president; Renato SotoPacheco, vice president; Luis PalenciaFranco, secretary; and Enriqueta Pizar-ro Suarez, treasurer. Their counterpartsin the Costa Rica Association were, re-spectively, Renato Soto Pacheco, RogerBolanos, Fernando Montero-Gei, andGuillermo Monge Amador.Newly elected officers of the Latin-

American Association are A. PomalesLebron, president; Jose Oliver Gonzales,secretary; and Irving Fox, treasurer.

The American Society for Micro-biology was officially represented byPhilipp Gerhardt, secretary, and R. W.Sarber, executive-secretary, who werewarmly received and included amongthe guests of honor. Their travel wassponsored by the National ScienceFoundation and Difco Laboratories,Inc.The Latin-American congresses are

convened at 3-year intervals. The firstwas held in Mexico City in 1958. Thethird is scheduled for 1964 in a placeyet to be named. It holds promise ofbeing as stimulating and rewarding asthe congress just concluded.

PHILIPP GERHARDTDepartment of Bacteriology,University of Michigan, Ann Arbor

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SCIENCE. VOL. 135

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Models molecular models-reallysuited to research and teaching in pro-tein chemistry: Courtauld space fillingmodels to be specific. Courtaulds haveredesigned and improved the criticallinkaLge mechanism, (atoms go togetherwithout tools) introduced hollow, highimpact polystyrene atoms, adjusted van

der Waals radii and bond angles torecent values, and cut the price.

It is quite literally true that it is dif-ficult to appreciate the really impressivesuperiority of these models until one

has actually manipulated a molecule,elastically distorted the bond angles, or

folded a chain into a complex structure.

Also these models have, in fact, per-

mitted structural insights previously un-

noticed. One can directly observe andmeasure the van der Waals envelope,steric hinderance, molecular packing,and elastic distortion of bond angles.

If chemical structures is your dish oftea, then you need Ealing's new Bro-chure THE NEW COURTAULDATOMIC MODELS. May we send it?

Or $5.00 gets you our IntroductoryKit of 4 assorted atoms, with their links,collars and spacers.

Why pay 64¢ for 28ml wide-formporcelain crucibles when Ealing sellsthem for 49¢? You'll find these and 683other budget stretchers in our new cata-log of LABORATORY GLASSWARE,PORCELAIN & FILTER PAPER. It'sfree.

The best low cost route we know ot

to a versatile mass spectrometer isEALING KIT Model 32-280 @ $235.It's Dartmouth University's ADP de-sign. Nine different EALING KITS are

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Alfano, ASAS, 663 Main St., Melrose 76,Mass.)

2-5. American College of Obstetriciansand Gynecologists, Chicago, Ill. (Chief ofInformation, Dept. of the Army, Wash-ington 25)

2-5. Instrument Soc. of America, instru-ment-automation conf. and exhibit, Pitts-burgh, Pa. (W. H. Kushnick, ISA, 313Sixth Ave., Pittsburgh 22)

2-13. Photogrammetry Week, Munich,Germany. (H. Bischoff, Zeiss-Aerotopog-raph G.M.P.H., Ismaniger Str. 57, Mun-ich 27)

3-5. Organic, Inorganic, and PhysicalChemistry, symp., annual, Chemical Soc.,Sheffield, England. (General Secretary,Burlington House, London, W.1, England)

3-5. Plasma Sheath, symp., Boston,Mass. (C. Ellis, Air Force Electronics Re-search Directorate (CRRD), L. G. Han-scom Field, Mass.)

3-6. Society of Automotive Engineers,natl. aeronautic, production forum and en-gineering display, New York, N.Y. (R. W.Crory, SAE, 485 Lexington Ave., NewYork 17)

3-7. Inter-American Nuclear EnergyCommission, Mexico City, Mexico.(TANEC, Pan American Union, Washing-ton 6)

4-6. Institute on Rehabilitation of theMentally Ill, New York, N.Y. (B. J. Black,Altro Health and Rehabilitation Services,Inc., New York)

4-6. Physics of Graphite-Moderated Re-actors, symp., Bournemouth, England.(Inst. of Physics and the Physical Soc., 47Belgrave Sq., London, S.W.1, England)

4-6. Short Run Production Techniques,intern. seminar, American Soc. of Tooland Manufacturing Engineers, MexicoCity, Mexico. (Conf. Director, ASTME,10700 Puritan Ave., Detroit 38, Mich.)

5-7. Pacific Sociological Assoc., annual,Sacramento, Calif. (R. Nisbet, Univ. ofCalifornia, Riverside)

6-8. American Soc. of Internal Medi-cine, annual, Philadelphia, Pa. (S. 0. Kras-noff, ASIM, 3410 Geary Blvd., San Fran-cisco 18, Calif.)

6-8. Association of Clinical Scientists,Chicago, Ill. (R. P. MacFate, 323 North-wood Rd., Riverside. Ill.)

6-8. Biological Photographic Assoc.,midwestern sectional, Des Moines, Iowa.(BPA, 551 W. Grant Place, Chicago14, Ill.)

7. New Jersey Acad. of Science, annual,West Long Branch. (H. L. Silverman,NJAS, 361 Highland Ave., Newark 4, N.J.)

7. New Mexico Acad. of Science, So-corro. (K. G. Melgaard, P.O. Box 546,Mesilla Park, N.M.)

7. Paleontological Research Institution,Ithaca, N.Y. (R. Harris, PRI, 109 Dear-born P1., Ithaca)

7-9. Impact of Physical Metallurgy onTechnology, symp., San Carlos de Bari-loche, Argentina. (J. A. Sabato, NationalAtomic Energy Commission, Avda. Liber-tador General San Martin 8250, BuenosAires, Argentina)

9-10. Chemical and Petroleum Instru-mentation Symp., natl., Instrument Soc. ofAmerica, Wilmington, Del. (C. W. Sand-ers, E. I. du Pont de Nemours & Co.,Louviers Bldg., Newark, Del.)(See 16 March issue for comprehensive list)

COLEMAN

Lowest cost-per-analysis with theColeman UniversalSpectrophotometer

In laboratories where cost andhigh-volume analytical output areimportant, the Coleman Univer-sal Spectrophotometer is still un-equalled.The instrument draws its speedfromtwo design features:... straightforward circuitry pro-vides direct-deflection readings interms of sample concentration.... a two-position sample carrierpermits almost instantaneous com-parison of unknown samples withthe reference standard.Added to its high-volume output are

these features:VERSATILITY-from high-speed rou-tine spectrophotometry, the Uni-versal readily adapts to the mostpainstaking measurements of fluo-rescence and light scattering...from macro to micro volumes. Acalibrated slidewire potentiometerpermits ultra-precise null readings.EXTENDED RANGE-Universal uses adiffraction grating to produce astraight and linear spectrum from325 to 825 mu. Its constant bandpass throughout the spectral rangeeliminates the need for mechani-cal slit adjustments.ACCURACY-results are reproduc-ible to ±0.2% full scale; scale islinear to 0.5 %. Wavelength calibra-tion easily kept within 0.5 %.In planning your laboratory instru-mentation, consider cost-per-analysis ... ask your dealer to dem-onstrate the Coleman Universal.Bulletin SB-241A on request.

COLEMAN INSTRUMENTS, INC.MAYWOOD, ILLINOIS

SCIENCE, VOL. 135