7
Improving Prophylactic Treatment of GBS Positive Patients Michelle Blythers Literature Review Presentation Senior Project October 22, 2014

Improving Prophylactic Treatment of GBS Positive Patients Michelle Blythers Literature Review Presentation Senior Project October 22, 2014

Embed Size (px)

Citation preview

Improving Prophylactic Treatment of GBS Positive Patients

Improving Prophylactic Treatment of GBS Positive PatientsMichelle BlythersLiterature Review PresentationSenior ProjectOctober 22, 2014

Introduction

A high priority should be placed on identifying Group B Streptococcus (GBS) positive mothers and the appropriate administration (>4 hours prior to delivery) of prophylactic antibiotics.

Importance of Change:

GBS is the leading cause of sepsis, pneumonia and meningitis in the early newborn period, which is defined a the first week of life.

Identifying/screening and adequately treating GBS positive mothers, increases positive patient outcomes.

Article #1 Berardi, A.,Rossi,C.,Biasini, A. Minnitti, S., Venturelli, C., Ferrari, Faccinetti, F. (2011) Efficacy of intrapartum chemoprophylaxis less than 4 hours duration. The Journal of Maternal-Fetal and neonatal medicine 21(4): 619-625The data in this article were collected over 12 months, in 2 different hospitals.This was a quantitative study to compare rate of vertical transmission of GBS in women with no other risk factors.The findings were valid.

Article #2 Turrentine, M. Greisinger, A., Brown, K., Wehmanen, O., Mouzoon, M. (2013). Duration of intrapartum antibiotics for group b streptococcus on the diagnosis of clinical neonatal sepsis. Infectious Disease in obstretrics and Gynocology, 1-6.doi:10.1155/2013/525878This particular study was done in a large facility which delivers over 8,000 infants a year.It was retrospective cohort study of.The results were that infants whose mothers received