In the Doctor's Office - Dawn Farm Education Series - 2012

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    Physicians Office: Friend or Foe

    Dawn Farm Education SeriesMarch 20, 2012

    Mark A. Weiner, MDPain Recovery Solutions, PC

    In theDoctors OfficeRecovery Friend or Foe?

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    This guycan be

    dangerous

    too!

    Initiation rates for nonmedical pain relieveruse continue to be second only tomarijuana rates, with 2 million or morenew nonmedical pain reliever users eachyear since 2002.

    The number of persons nation-widereceiving specialty substance usetreatment within the past year for misuseof pain relievers more than doubled: from199,000 in 2002 to 406,000 in 2010.

    www.oas.samhsa.gov/NSDUH/2k10NSDUH/2k10Results.htm

    A national survey of residencyprogram directors found only 56% of the programs require training in

    substance use disorders. Even whentraining is required, very little isprovidedmedian curriculum hoursranged from 3 to 12.

    www.hazelden.org/web/public/document/bcrup_0903.pdf

    In a study of third-year medicalstudents, only 19% recognizedalcoholism during a mock chart reviewexamination, even though thealcoholism diagnosis, a family historyof alcoholism, and a 10-year history of extensive alcohol use were includedprominently throughout the chart.

    www.hazelden.org/web/public/document/bcrup_0903.pdf

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    94% of primary care physicians failedto diagnose substance abuse whenpresented with early symptoms of alcohol abuse in an adult patient.

    www.centerforhealthandjustice.org/BOSUDsandPrimaryCare.pdf

    29.5% of patients (in treatment for

    substance abuse) said theirphysicians knew about theiraddiction and prescribedpsychoactive drugs such as sedativesor Valium.

    www.centerforhealthandjustice.org/BOSUDsandPrimaryCare.pdf

    Public Policy Statement on Measures toCounteract Prescription Drug Diversion, Misuse

    and Addiction - ASAM BOD, 01/25/12.

    Studies have shown that physicians have notreceived adequate education about thepotential psychiatric and addictionconsequences of the decision to prescribescheduled medication. Most practicingphysicians have had little if any formal trainingin addiction. Few physicians demonstrate

    understanding of the etiology of addiction. . ...

    Policy statement, ASAM 2012 Although issues of tolerance and withdrawal

    are understood to exist, most physicians are notaware of the mechanisms and the behavioralconsequences of these phenomena, or therelationship of these phenomena to addiction.Confusion still exists whereby some cliniciansmistake physical dependence (tolerance andwithdrawal) for addiction. Rarely are craving andreward seeking behaviors appreciated byprescribers as being potential consequences of theirprescribing of opioid and sedative medications. ...

    Policy statement, ASAM 2012

    But there is emerging data to suggest thatwhen primary care physicians are targeted forfocused education regarding pain, painmedication prescribing, and assessing patientsfor risk prior to the initiation of opioidanalgesic therapy, trends in opioid overdosedeaths can be reversed.

    http://www.asam.org/docs/publicy-policy-statements/1-counteract-drug-diversion-1-12.pdf

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    FeelingCrappy?

    Headaches

    Insomnia Depression Anxiety Stomach

    problems

    Back pain Attention

    problems

    Even if heknows yourean addict and

    really wants tosupport your

    recovery,whats his firstquestion likely

    to be?

    Sobriety Based Symptoms of Addiction

    Restless Irritable Discontent Physical Manifestations

    Abstinence

    Recovery

    Recovering People ShouldPlan Ahead

    Decision making can beimpaired when we experienceacute discomfort

    Safe,

    NewMeds?

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    So

    The doctors office can be a dangerousplace for recovering people

    Dawn Farm has been working onconnecting clients with recoverycompetent primary care and talking toprimary care providers and medicalstudents about addiction and recovery

    ARE WE THINKING ABOUTADDICTION TREATMENTAPPROPRIATELY?

    Treatment for Hypertension:High symptoms reduced symptoms symptoms return

    Treatment Status Over Time

    B l o o d P r e s s u r e :

    m m

    H g

    No Tx Tx Tx Tx No Tx

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    Did treatment work?

    Treatment Status Over Time

    A l c o

    h o

    l C o n s u m p t i o n

    No Tx Tx Tx Tx No Tx

    Treatment for Alcoholism:

    Did addictiontreatment work? Acute care model

    vs.

    Chronic illness

    management model

    IS ADDICTION TREATMENT AS

    EFFECTIVE AS TREATMENT FOR

    OTHER HEALTH PROBLEMS?

    How doesHow doesasthma compare?asthma compare?

    Medication compliance: 30%

    Relapse Rate: 60 to 80%

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    How doesHow doeshypertensionhypertension

    compare?compare?

    Medication

    And Diet

    Compliance: 30%

    Relapse Rate: 60-80%

    How doesHow doesdiabetes compare?diabetes compare?

    Medication, diet

    and foot care

    Compliance:

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    What happenswhen we treataddiction as a

    chronic illness???People like

    this guy findrecovery!

    Long term residential treatmentfollowed by

    Long term outpatientfollowed by

    Long term recovery monitoring

    With sober social support

    How do we give this kindof care to everyone else?

    1. Theyre different!

    2. Too expensive! 4. Theyre hopeless!

    3. You have no stick!

    DawnFarm hasgottenprettygood atthis, but

    It takes about 5 years foralcoholism relapse rates to drop

    below 15% and about 7 years foropiate addiction relapse rates todrop below 15%

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    Make ThisGuy an Ally

    Preventmedicationrelatedrelapses

    Pain plan Recovery-

    informed care

    Make ThisGuy an Ally

    Long termrecoverysupport andmonitoring

    Recoverycheck ups

    Rapid re-stabilization

    Declarations of PotentialConflicts of Interest

    I have no financial relationship with anypharmaceutical company

    The content of this presentation is non-commercial and does not represent anyconflict of interest or commercial bias

    I will mention the use of medications for indications that are not FDA approved (but

    you will be informed when that happens)

    Special Thanks Herb Malinoff, MD Carl Christensen, MD, PhD Edward Covington, MD Doug Gourlay, MD Howard Heit, MD Donald Kurth, MD Edwin Salsitz, MD

    Michigan Pain Specialists The Medical Staff at St. Joseph Mercy Hospital

    The many patients who have entrusted me with their care

    Objectives

    Learn how drugs act on our brains Very, very basic neurobiology of relapse

    Be able to tell your doctor you are inrecovery Discuss issues regarding pain, insomnia,

    anxiety and depression in addiction LOTS of time for Q & A

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    Basic Neurobiology of Addiction

    Addiction requires activation of the

    pleasure center circuit This is a normal useful part of the brain

    with enhances our survival It make us feel good when we do things

    that keep us alive or reproducing (food,sex, shelter, etc)

    Involved in SALIENCE

    Basic Neurobiology of Addiction

    It is a very powerful modulator of memory,

    emotions, motivation and logic In addiction, this center is high-jacked and

    results in harm Once activated by addiction, its response

    is permanently altered It can be easily reactivated by drugs, cues

    and stress

    What is Salience

    Important That which is remembered most Meaningful Example of normal salience [ripe fruit ->

    good to eat -> color, location, season]

    VTA

    Ventral TegmentalArea (midbrain)

    Pleasure Circuit

    VTA

    NANucleus

    Accumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure Circuit

    VTA

    NANucleus

    Accumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure Circuit

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    VTA

    NucleusAccumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure Circuit

    VTA

    NucleusAccumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitCortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    Ventral Pallidum (motivation)

    VTA

    NANucleus

    Accumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitAmphetamineCocaineOpiatesCannabinoidsPhencyclidineKetamine

    OpiatesEthanolBarbituratesBenzodiazepinesNicotineCannabinoids

    VTA

    NANucleus

    Accumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitAmphetamineCocaineOpiatesCannabinoidsPhencyclidineKetamine

    OpiatesEthanolBarbituratesBenzodiazepinesNicotineCannabinoids

    Cortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    Ventral Pallidum (motivation)

    VTA

    NucleusAccumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitCortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    Ventral Pallidum (motivation)

    VTA

    NucleusAccumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitCortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    AmphetamineCocaineOpiatesCannabinoidsPhencyclidineKetamine

    OpiatesEthanolBarbituratesBenzodiazepinesNicotineCannabinoids

    DOPAMINEDOPAMINE

    Ventral Pallidum (motivation)

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    VTA

    NucleusAccumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitCortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    AmphetamineCocaineOpiatesCannabinoidsPhencyclidineKetamine

    OpiatesEthanolBarbituratesBenzodiazepinesNicotineCannabinoids

    DOPAMINEDOPAMINE

    Ventral Pallidum (motivation)

    VTA

    NucleusAccumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitCortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    AmphetamineCocaineOpiatesCannabinoidsPhencyclidineKetamine

    OpiatesEthanolBarbituratesBenzodiazepinesNicotineCannabinoids

    DOPAMINEDOPAMINE

    Ventral Pallidum (motivation)

    VTA

    NANucleus

    Accumbens(striatum)

    Ventral TegmentalArea (midbrain)

    Pleasure CircuitAmphetamineCocaineOpiatesCannabinoidsPhencyclidineKetamine

    OpiatesEthanolBarbituratesBenzodiazepinesNicotineCannabinoids

    Cortex(logic)

    Hippocampus (memory)

    Amygdala (emotions)

    Ventral Pallidum (motivation)

    Abnormally Salient

    SO Important -> essential for life LONGEST LASTING MEMORIES As important as oxygen A Description of Abnormal Salience

    Are Prescription Drugsa Drug Problem

    YES!

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    How to Tell Your Doctors YouAre In Recovery

    Tell them early

    Doc, I am in recovery from drugs andalcohol. I need your help by notprescribing drugs that are addictive. Doyou know enough about addiction to keepme safe?

    Repeat yourself Repeat yourself

    Should Addicts and Alcoholics BeDenied Treatment

    NO!

    An addict or alcoholic, especially in earlyrecovery, deserves the exact same careand relief of pain, insomnia, depression,anxiety, etc

    Ignoring these symptoms creates anunstable situation (likelihood for relapse)

    The care is different (can be better in some ways)than the care of the non-addict

    Why Do People In Recovery GoTo The Doctor

    The same reason everyone does: Pain (back, joint, headache, teeth => dentist) Sleep problems Concentration problems Depression Anxiety Colds, coughs, etc.

    What is Narcotic / Non-Narcotic?

    Not a very useful term A controlled substance (legal)? A prohibited drug (legal)? Causes sleep (ancient term)?

    Tramadol / Ultram Carisoprodol / Soma

    Take Home Point: Non-narcotic does NOT mean non-addictive!

    Types of Problematic Medications

    Opiates Vicodin, Vicoprofen, Norco, Lorcet, Percocet, Morphine, rx cough

    syrup

    Benzodiazepine Sedatives Xanax, Ativan, Valium, Restoril, Ambien, Lunesta, Sonata Other sedatives

    Fiorocet, Benedryl, many antihistamines

    Dissociatives OTC cough syrup, dextromethorophan, DXM

    Steroids prednisone???

    Types of Problematic Medications

    Stimulants Adderal, Concerta, Ritilan

    Alcohol Containing Medication / Items NyQuil 25% alcohol = 50 proof Listerine 26.9%, Scope 18.9%, Signal 14.5%,

    Cepacol 14.0%, Listermint 6.6% Beer 4-6% Wine 13-15% Brandy 35%

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    Types of Problematic Medications

    Natural and Herbal

    Does not mean it is safe Valerian Root Kava Kava Anything that makes one sleepy, awake, changes

    mood or energy level is suspect

    Treating Pain In Addiction

    Fallacy: The best pain meds are opiates

    and we are saving them for the non-addicts

    The pain relieving effects of opiatesinvolve direct action on the brain

    Many other drugs are more effective atcontrolling pain (naproxen, Tylenol)without CNS effects

    Treating Pain In Addiction

    The use of opiate pain medications(including tramadol) can lead to extremecravings in addicts/alcoholics no matter how long they have been sober

    Patients who have had both experiencestell me the craving is far more miserablethan any physical pain

    Acute pain Treatment NSAIDs Motrin, Naproxen, Torodol Other Tylenol 8 hour Ice Rest, splint

    Chronic Pain Buprenorphine? --- not necessarily safe, but

    definitely safer if opiates are being considered

    Treating Pain In Addiction

    Anxiety In Addiction

    Social anxiety is nearly universal Newly recovering addicts have lost many

    friends and feel alone The drugs and alcohol were an effective

    coping mechanisms (with deadly sideeffects)

    This anxiety usually goes away with time

    Anxiety In Addiction

    We should not ignore the fact that 2-5% of people have generalized anxiety disorder

    Many primary care doctors andpsychiatrists will prescribe addictivesedatives

    Benzodiazepines (Xanax, Klonopin, Ativan) often produce extreme cravings for alcohol

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    Anxiety In Addiction

    There are MANY safe and non-addictive

    treatments for anxiety disorder Sedatives are slowly falling out of favor as

    even psychiatrists see the problems of abuse and dependence without relief of sx

    The symptoms of benzo withdrawal areindistinguishable from anxiety disorder

    May require assessment from andaddiction psychiatrist

    Insomnia

    Very common in early recovery

    Natural sleep centers are not functioningproperly

    Improves universally without medicine butmay take a long time

    Most common sleeping medications canactivate the addiction center

    May require assessment from andaddiction psychiatrist

    Insomnia

    If problems persist and are interfering with job, responsibilities, etc., there are manysafe alternatives

    Unfortunately many doctors believe thatsome very addictive sleeping meds aresafe (ambien, lunesta, sonata)

    Some natural supplements can be helpful(melatonin)

    Depression

    Essentially universal in early recovery Often resolves quickly with full

    engagement in 12-step recovery If persistent, counseling or psychiatric

    assessment is warranted Medications may be necessary but often

    are not

    Depression

    Without an understanding of addiction,many psychiatrists arguably overprescribeleading to overmedication and poorer cognitive and social functioning

    Is There Such Thing As A DrugOf Choice?

    Any substance that activates the addictioncenter can cause relapse

    Generally the memory centers will drivethe addict to a specific reinforcing drug

    Shark Tank Example

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    Is There Such Thing As A DrugOf Choice?

    The fact is that most alcoholics, for reasons yet

    obscure, have lost the power of choice in drink.Our so-called will power becomes practically nonexistent. We are unable, at certain times, tobring into our consciousness with sufficient force the memory of the suffering and humiliation of even a week or a month ago. Weare without defense against the first drink.

    - Alcoholics Anonymous p. 24

    So What Do I Do Now?

    Be very careful about medication use

    Consult with a board certified AddictionMedicine doctor

    Call your Addiction Medicine doctor PRIOR to taking any new pills for pain,insomnia, sleep, depression, etc

    So What Do I Do Now?

    It is probably not a good idea to get adviceon whether to start or stop any medicationfrom your sponsor or recovery supports

    What is Tradition 10?Alcoholics Anonymous has no opinionon outside issues ; hence the A.A. nameought never be drawn into public controversy.

    Q&A

    How to Contact Me

    Pain Recovery Solutions, PCYpsilanti, MI

    734 [email protected]

    The End