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Accredited (2014 - 2019)by the Directorate General of Higher Education of the Ministry of Education and Culture of the Republic of IndonesiaNo.: 212/P/2014, 3 Juli 2014

Official Publication ofIndonesian Society of Obstetrics and Gynecology

www.inajog.com

INAJOGpISSN: 2338-6401-eISSN: 2338-7335

IndonesianJournal ofObstetrics andGynecology

Founded 1974Volume: 6, No. 1, page 1 - 68 January 2018

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EditorialStress Urinary Incontinence (SUI): Conservative and Surgical Approach

Research ArticlesEffectiveness of Oral Probiotics (Lactobacillus Rhamnosus Gr-1 and Lactobacillus Reuteri RC-14) as Adjuvant Therapy in Reproductive Aged Women with Vaginal Discharge

The Association between Menstrual Disorder and Work Disturbance among Employees

The Association of C-Reactive Protein Levels in Second Trimester of Pregnancy with Preeclampsia

Relationship between Vaginal Sialidase Levels with Threatened of Preterm Labour

Internet Based Infertility Information in Bahasa Indonesia Quality Survey

Pregnancy Outcome in Infertility Patient with Endometriosis Cyst after Laparoscopic Cystectomy

Relationship between Knowledge, Attitude and Behavior of Postnatal Woman Toward Participation in Permanent Contraception

A Comparative Study of Nomegestrol Acetate and a Combina- tion of Ethinylestradiol and Levonorgestrel for Delaying Menstruation among Umrah Pilgrims

L-selectin Levels in Patients with Endometriosis

Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery

Incidence of Pelvic and Paraaortic Lymph Node Metastasis in Epithelial Ovarian Cancer at a Tertiary Care Center

The Effect of Cyclophosphamide Chemotherapy on Ovarian Anti-Müllerian Hormone Levels in Breast Cancer Patients

Editorial BoardIndonesian Journal of Obstetrics and GynecologyIndones J Obstet Gynecol

Editor‐in‐ChiefDr. dr. Junita Indarti, SpOG(K)

Deputy Editor‐in‐ChiefDr. dr. Dwiana Ocviyanti, SpOG(K) dr. Andon Hestiantoro, SpOG(K)

Managing EditorsProf. Dr. dr. Wachyu Hadisaputra, SpOG(K)Dr. dr. Laila Nuranna, SpOG(K)Dr. dr. Eka R Gunardi, SpOG(K)Dr. dr. Budi I Santoso, SpOG(K)Dr. dr. Ali Sungkar, SpOG(K)

dr. Herbert Situmorang, SpOG(K)dr. Kartiwa H Nuryanto, SpOG(K)Dr. dr. Tono Djuwantono, SpOG(K), M.KesDr. dr. Hariyono Winarto, SpOG(K)Dr. dr. Budi Wiweko, SpOG(K)

Peer ReviewerProf. Dr. dr. Andrijono, SpOG(K)Prof. dr. Ariawan Soejoenoes, SpOG(K)dr. Arietta Pusponegoro, SpOG(K)dr. Fernandi Moegni, SpOG(K)dr. Gita Pratama, SpOGdr. Nuswil Bernolian, SpOG(K)dr. Rizal Sanif, SpOG(K)Dr. dr. Sri Sulistyawati, SpOG(K)Dr. dr. Suskhan Djusad, SpOG(K)Dr. dr. Tatit Nurseta, SpOG(K)

Gynecologic OncologySocial Obstetrics and GynecologySocial Obstetrics and GynecologyUrogynecologyReproductive ImmunoendocrinologyFetomaternalGynecologic OncologyFetomaternalUrogynecologyGynecologic Oncology

International Peer ReviewerProfessor Young Min Choi, MD, Ph.DDepartment Obstetrics and Gynecology, Director the Institute of Reproductive Medicine and Population,Medical Research Center, Seoul. Korea

English Consultantdr. Amy Cynthia de Meriyenes

SecretariatFrachma Della Siregar Eko Subaktiansyah

PublisherIndonesian Society of Obstetrics and Gynecology

Correspondence AddressPKMI Building, Ground FloorKramat Sentiong 49 A, Central Jakarta 10450, IndonesiaTelephone: 021‐3916670,  Fax.: 021‐3916671E‐mail: inajog.indonesia@gmail.com;  majalah_mogi@yahoo.comWebsite: www.indonesia.digitaljournals.org/index.php.ijogpISSN: 2338‐6401 ‐‐ eISSN: 2338‐7335

Printed by Tridasa Printer, Jakarta.

Majalah Obstetri dan Ginekologi Indonesia (MOGI) is the official publication of the Association of Obstetrics and GynecologyIndonesia since 1974, the name is changed into Indonesian Journal of Obstetrics and Gynecology (INAJOG). Due to this fact,we announced that the ISSN number will be changed from ISSN 0303‐7924 into 2338‐6401, and starting from July 2013 edition,the volume will be changed into Volume 1 No 3.

INDONESIAN JOURNAL OF OBSTETRICS AND GYNECOLOGYIndones  J Obstet Gynecol

Majalah Obstetri dan Ginekologi  Indonesia

CONTENTVolume 6, Number 1, Page 1 – 68, January 2018Editorial

Budi  I. SantosoJakarta 2 Stress Urinary Incontinence (SUI): Conservative and Surgical Approach

Research ArticlesJunita  Indarti

Utomo BudidarmoJakarta 3 Effectiveness of Oral Probiotics (Lactobacillus Rhamnosus Gr­1 and LactobacillusReuteri RC­14) as Adjuvant Therapy  in Reproductive Aged Women with VaginalDischargeThere was no clinical and statistical difference in the proportion of cure rate and the level ofsatisfaction in patients of probiotics vs placebo groups after treatment for 4 weeks. The initialhypothesis of higher proportion of the cure rate in the treatment group still cannot beexcluded, due to insufficient samples.

I.P.G. KayikaIftikar Abdullah

Gita PratamaLaila NurannaJakarta

10 The Association between Menstrual Disorder and Work Disturbance amongEmployeesThe prevalence of severe work disturbance due to menstruation is not high but can lead todisruption in running jobs and activities. However, it is important to be a concern sothat the employees get good management and care.

Zulfaekasari NasruddinEfendi LukasUmar Malinta

Maisuri T. ChalidMakassar18 The  Association  of  C­Reactive  Protein  Levels  in  Second  Trimester  of  Pregnancy

with PreeclampsiaThe average score of C-Reactive protein of preeclampsia group is 33.5% higher than non-preeclampsia group, even though these results cannot be used as the score topredict the preeclampsia occurrence.Bambang SulistyoNajoan N. Warouw

Eddy SuparmanManado 23 Relationship between Vaginal Sialidase Levels with Threatened of Preterm LabourThere is a relationship between the incidence threatened of preterm labor with vaginal sialidaselevels.Andon Hestiantoro

Intan KusumaningtyasJakarta 28 Internet Based Infertility Information in Bahasa Indonesia Quality SurveyThe quality of internet based infertility information in Bahasa is adequate for category credibility,accuracy and ease of navigation.Eka R. GunardiDuta A. Tritama

Luky SatriaHerbert SitumorangJakarta

34 Pregnancy Outcome in Infertility Patient with Endometriosis Cyst afterLaparoscopic CystectomyThe pregnancy rate after laparoscopic procedure is 35,9% in this study. There are correlationbetween age, duration of infertility, and r-AFS staging with pregnancy rate.

Jhon HeriansyahAzhari

Firmansyah BasirTheodorusPalembang

39 Relationship between Knowledge, Attitude and Behavior of Postnatal WomanToward Participation in Permanent ContraceptionFactors that influence the participation of women in RSMH safe contraception Palembang includesupport for her husband and behavior.

Mirzah TindarYusuf EffendiAdenan Abadi

TheodorusPalembang45 A Comparative Study of Nomegestrol Acetate and a Combination of Ethinylestra­

diol and Levonorgestrel for Delaying Menstruation among Umrah PilgrimsThere is no difference in effectiveness between nomegestrol acetate 5 mg or combination oflevonorgestrel 150 mcg and 30 mcg ethinylestradiol as a regimen for delaying menses in Umrahpilgrims in Palembang city.Melkiandri Fanggidae

Maria F.T. LohoMaya E. MewengkangManado 50 L­selectin Levels in Patients with EndometriosisL-selectin levels in women with endometriosis increased according to clinical stage, but notsignificant in statistical tests. There is no significant relationship between age withstages or levels of L-selectin in women with endometriosis.

Azizah NurdinTrika  Irianta

Mardiah TahirMaisuri T. ChalidMakassar

55 Obstetric Risk Factors and Anal Incontinence among Women with PreviousHistory of Vaginal DeliveryParity, vacuum delivery and prolong second stage of labor have an association with analincontinence among women who has history of vaginal delivery

AndrijonoRisa RisfiandiJakarta 60 Incidence of Pelvic and Paraaortic Lymph Node Metastasis  in Epithelial Ovarian

Cancer at a Tertiary Care CenterLymph node metastasis incident of ovarian epithelial cancer in paraaorta amounts 20%, pelvic9.1% and pelvic or paraaortic 23.6%. Higher the stadium, the lymph node involvements will behigher as well (pelvic and paraaortic). In stadium 1 of mucinous subtype with well differentationhas minimal lymph node involvement so we can be more selective in considering the risk andbenefit of lymphadenectomy.Elisabeth G.K. Liga

Nusratuddin AbdullahEddy Tiro

Maisuri T. ChalidMakassar64 The Effect of Cyclophosphamide Chemotherapy on Ovarian Anti­Müllerian

Hormone Levels in Breast Cancer PatientsAMH levels decreased significant after cyclophosphamide indicated that cyclosphosphamidedecrease ovarian reserve.

EDITORIAL

Stress Urinary Incontinence (SUI): Conservative and Surgical Approach

Budi I Santoso

Stress urinary incontinence (SUI) is defined as the involuntary leakage of urine at exertion or increasedabdominal pressure. It affects approximately 4-35% of women and impacts the quality of women’s life.1,2 Thetreatment for SUI can be divided into conservative and surgical approaches. Conservative treatmentincludes pelvic muscle exercise (PME) or incontinence pessaries. A pelvic muscle exercise known as Kegelis used for urge, stress, and mixed continence for strengthening the muscular components of urethral closuremechanism.3 Meanwhile, duloxetine is believed to be effective in treating SUI.4 Expert opinion stated that trialof anticholinergic drug in patients with mixed urinary incontinence can be reasonable at the availability of urgesymptoms.5For surgical procedure, there are several approaches including vaginal through mid-urethral sling, bladderneck sling, injection of urethral bulking agents, abdominal through Burch retropubic colpo-suspension. A meta-analysis revealed that mid-urethral slings were comparable with other procedures. Shorter operative duration,similar rate of perioperative complication, similar frequency of adverse effects on bladder, and shorter hospitalstay were shown in patients choosing mid-urethral sling.6 Therefore, mid-urethral sling has become one of thebest choice for women with SUI desiring surgical treatment. However, only apical prolapse that should betreated with open abdominal sacrocolpopexy (Burch colposuspension).7 In conclusion, conservative approachis still an option for SUI women refusing surgery and mid-urethral sling becomes a preferable technique forSUI due to the exception in SUI with apical prolapse.

References1. Haylen BT, de Ridder D, Freeman RM, et al. An International Urogynecological Association (IUGA)/International ContinenceSociety (ICS) joint report on the terminology for female pelvic floor dysfunction. Neurourol Urodyn 2010; 29: 4.2. Kane AR, Nager CW. Midurethral slings for stress urinary incontinence. Clin Obstet Gynecol 2008; 51: 124.3. Hay-Smith J, Berghmans BK, et al. Adult conservative management. In: Incontinence, 4th Ed., Abrams P, Cardozo L, Khoury S, WeinA (Eds), Health Publications Ltd, Paris 2009: 1025.4. van Kerrebroeck P, Abrams P, Lange R, et al. Duloxetine versus placebo in the treatment of European and Canadian women withstress urinary incontinence. BJOG 2004; 111: 249.5. Mariappan P, Ballantyne Z, N’Dow JM, Alhasso AA. Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinaryincontinence in adults. Cochrane Database Syst Rev 2005: CD004742.6. Ogah J, Cody JD, Rogerson L. Minimally invasive synthetic suburethral sling operations for stress urinary incontinence in women.Cochrane Database Syst Rev 2009: CD006375.7. Maher CF, Qatawneh AM, Dwyer PL, et al. Abdominal sacral colpopexy or vaginal sacrospinous colpopexy for vaginal vaultprolapse: a prospective randomized study. Am J Obstet Gynecol 2004; 190: 20.

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