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Influenza
Influenza Virus magnified 100,000X
What is Influenza?
Virus; causes chills, fever, sore throat, fatigue
How many people die each year from Influenza?
250,000 – 500,00 worldwide; 40,000 in US
(7th leading cause of death)
USA
How many people died in 1918 from Influenza?
40 – 100 million people
(3% of world’s population; as many that died in all wars in 20th century combined)
How many people died in 1918 from Influenza?
Did more people die because more people were infected with
Influenza?Usually – 0.1% of people infected die
1918 – about 10% of all infected people died
Who was dying?Young adults
Have there been other influenza epidemics since 1918?
Asian Flu (1957) – 1.5 million people died
Hong Kong Flu (1968) – 1 million people died
Influenza which caused the Hong Kong Flu
What made the 1918 Influenza virus so powerful and why did scientists think that
this year’s virus would be so bad?
Hemagglutinin – helps with viral entry (16 types)
Neuraminidase – helps with viral release (9 types)Asian Flu (1957) – Type H2N2Hong Kong Flu (1968) – Type H3N2
1918 Flu - H1N1
How do new Influenza Viruses
form?
Influenza can infect birds, humans, and pigs
How do new Influenza Viruses form?
Antigenic Shift – Influenza can infect pigs, birds, humans; parts from different virus strains are mixed.
2006 – Avian FluH1N7H5N1
H1N1
Link to Nova SCIENCENOW Video