Early development: Cleavage: patterns and control. Gastrulation: Morphogenetic movement of cells and cellular rearrangements in amphibian, Fate maps. Early development in birds. Early developments in mammals (Humans). Formation of Embryonic axis, Functions of the Organizer and Mechanism of Induction. Regional Specificity of Induction. Course Contents February 13, 20163Introduction
Instructor: Dr. Shahzad A. Mufti Advisor Department of
Biosciences Developmental Biology BIO-233 Introduction: Asexual and
Sexual reproduction. History of embryology. Gametogenesis:
Oogenesis and Spermatogenesis. Molecular events during Oogenesis,
Nuclear and Cytoplasmic events, Spermatogenesis and Spermiogenesis.
Fertilization: External and Internal, Egg and Sperm recognition,
Activation of Gamete metabolism, Fusion of Genetic material. Course
Contents February 13, 20162Introduction Early development:
Cleavage: patterns and control. Gastrulation: Morphogenetic
movement of cells and cellular rearrangements in amphibian, Fate
maps. Early development in birds. Early developments in mammals
(Humans). Formation of Embryonic axis, Functions of the Organizer
and Mechanism of Induction. Regional Specificity of Induction.
Course Contents February 13, 20163Introduction A breif description
of organogenesis in vertebrates. Metamorphosis in Amphibia.
Regeneration: Epimorphosis in Urodeles. Aging: the Biology of
Senescence. Medical implications of Developmental biology,
Teratogenesis: Genetic and Environmental causes. Cloning, Gene
therapy and Stem cell research. Course Contents February 13,
20164Introduction February 13, 20165Introduction Text / Reference
Books Developmental Biology, by Scott F. Gillbert. 8 th Ed. (2006).
Sinauer Associates, Inc. Massachusetts. Analysis of Biological
Development, by Klaus Kalthoff. 2 nd Ed. (2001) McGraw Hill, New
York. Principles of Developmental Biology, by Fred H. Wilt and
Sarah Hake (2004) W. W. Norton &Co., New York, London. February
13, 20166Introduction First Sessional = 10% Quiz-1 = 7% Second
Sessional = 15% Quiz-2 = 8% Lab = 10% Final = 50% Marks
Distribution February 13, 20167Introduction Reproduction: One of
three Basic instincts Asexual and Sexual Reproduction. Scope of
study. Phases of development: ontogenetic cycle. History of
Developmental Biology: Aristotles (350 BC) times to Harveys time
(1651); studies on chick embryo. February 13, 20168Introduction
Theories of Preformation (Bonnet, 1764) and Epigenesis (Wolff,
1767). Von Baers work (1828). First book Baers Law: Ontogeny
recapitulates phylogeny. Biogenetic Law of Muller-Haeckle (1868)
Discovery of Cell; demise of preformation. The new interpretation
of Preformation and Epigenesis. February 13, 20169Introduction
Developmental Biology is one of the fastest growing and most
exciting field in biology, creating a framework that integrates
molecular biology, physiology, cell biology, genetics, anatomy,
cancer research, neurobiology, immunology, ecology and evolutionary
biology. The study of development has become essential for
understanding any other area of biology.* * S. F. Gilbert,
Developmental Biology, Page 4. February 13, Introduction February
13, Introduction February 13, Introduction February 13,
Introduction February 13, Introduction February 13, Introduction
February 13, Introduction
