Instrumental Analysis

(CHEM 4811)

Section 01 (CRN 26097)

TR 12:45 - 2:00 (LAB 107)

DR. AUGUSTINE OFORI AGYEMANAssistant professor of chemistryDepartment of natural sciences

Clayton state university

• My homepage is http://a-s.clayton.edu/aagyeman/

• Email: aagyeman@clayton.edu

• Office: Natural & Behavioral Sciences Building, NBS 147

• Phone: (678) 466 4793

• Office Hours: M: 10:00 am - 1:00 pm W: 10:00 am - 1:00 pm or by appointment

CONTACT INFORMATION

COURSE POLICIES

• Make sure you sign in each day you come to class– Under no circumstances should a student sign in for

someone else

• If you are not in the right class, request a change (on-line in the duck)– Give me a feed back

COURSE POLICIES

• Attendance: – Attend and participate in every class meeting– Inform me via email if you cannot attend a class in a particular day– Habitual absentees may be penalized– Habitual tardiness will not be tolerated

• I am here to help you; contact me any time, any day; take good advantage of that; let’s build a healthy relationship

COURSE POLICIES

Just coming to class is not enough– Download, print and read course materials before coming to

class– Pay attention to the instructor– Participate in class activities (try to answer questions, be

involved in class discussions)– Ask questions– Join group discussions– Read notes and other materials everyday and solve a lot of

questions– Turn in every homework given you (submit on or before due

dates)– Always be prepared for quizzes and exams– All the above are still not enough

• Notebook computers should not be opened unless authorized to do so

• Computers and/or cell phones cannot be used as a calculator for exams

• Cell phones must be completely turned off

COURSE POLICIES

• Academic Misconduct– Common forms: cheating, plagiarism– Academic dishonesty will result in a grade of zero for

the work involved and reported to the office of Student Life/Judicial affairs

• Disruptive behavior (abusive, threatening, profane) will not be tolerated

• No eating, drinking, or smoking in the classrooms

COURSE POLICIES

• Grades:

3 examinations at 100 each 300Term paper 100Homework 100Final Exam (comprehensive) 200Total 700

Late assignments will be penalized (10% per day)Bonus quizzes may be given throughout the semester to help

students earn additional points

COURSE POLICIES

• Grades– Midterm grades reflect about 20% of total grade– Students may choose to withdraw– Withdrawal deadline is March 2, 2012– Must fill official withdrawal form (Registrar’s

office)– No grades will be given out over phone or email– Complete student survey and course/instructor

evaluation at the end of semester

COURSE POLICIES

• Grades:

A 90% or greater

B 80% - 89%

C 70% - 79%

D 60% - 69%

F less than 60

COURSE POLICIES

• Tentative Course Schedule

COURSE POLICIES

INTRODUCTION• Course Description

– CHEM 4811 (one-semester course)

• Theoretical principles and uses of modern instrumental methods

– Designed for SCIENCE MAJORS (Chemistry, Biology, Physics, Pre-medicine, Pre-pharmacy, Forensic Science, Forestry, Engineering, etc)

– Major topics include spectroscopy, electroanalysis, and chromatographic separations

INTRODUCTION

Course Objectives

Students should be able to:

• Design analytical methods and assess experimental data• Describe principles of NMR, IR, UV-VIS, and X-Ray spectroscopy• Analyze electroanalytical methods• Describe principles and applications of mass spectrometry• Describe principles and applications of chromatographic

separations

• Interpret spectral data

INTRODUCTION

• Course syllabus

– Note prerequisites and co-requisites

– Prerequisite: CHEM 2412/L and CHEM 3811

– Co-requisite: CHEM 4811L

– See me after class if you do not meet them

INTRODUCTION

• Textbook Robinson, James W., Skelly Frame, Eileen M., Frame, George M., Undergraduate Instrumental Analysis, 6th edition, CRC Press, New York, 2005.

• Chapters 1 – 16

INTRODUCTION

What Is Chemistry?

- The central science (it merges into physics and biology)

- The study of matter and energy and the interactions between them

- The branch of the natural sciences concerned with the characteristics, composition, and transformations of matter.

- Everything we hear, smell, taste, see, and touch involves chemistry and chemicals (matter)

INTRODUCTION

Divisions

- Analytical (methods of analysis of matter)

- Physical (theory and concepts of chemical problems)

- Organic (compounds of carbon)

- Inorganic (compounds of elements other than carbon)

- Biochemistry (compounds of living matter)

INTRODUCTION

What Is Instrumental Analytical Chemistry?

The use of modern automated instrumental methods for

- The qualitative and quantitative characterization of matter

- Identification and quantification of the constituents of matter

- Studying the chemical composition of materials

- Analyzing chemicals for their composition and structure

INTRODUCTION

Why Study Instrumental Analytical Chemistry?

- To understand the chemical composition of all matter

- Plays important role in the pharmaceutical industry (discovery of new drugs)

- Quality control of industrial manufacturing

- Environmental monitoring

- Biomedical applications

Analytical Methods

- Gravimetry (based on weight)

- Titrimetry (based on volume)

- Electrochemical (potential, current, charge, etc)

- Spectral (the use of electromagnetic radiation)

- Chromatography (separation of materials)

- Chemometrics (statistical treatment of data)

INTRODUCTION