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Seafood
$200B
$2 Trillion(2020)
Beef
$800B
10xresource
intensive > soy
70%of
deforestation
18%of GHG
emissions
Footprints
Animal Agriculture (And Its Environmental Cost) Is Growing
2
~2016Conventional
$2
Growth factors
Consumables
CapEx
Serum-free
2017Lab scale
2026 large scale plant
”Culnet System” : General purpose large-scale cell culture
Cells[A]
Cells[B]
Dia
lysis
, oxyg
en
atio
n e
tc.M
usc
le c
ells
PCT/JP2016/067599
Japan Pat.6111510
Cell culture cost
1/10000$600K/kg
$2K
How Culnet System works - “Coculture”
5
Cell culture medium Inter-cellular interactions
Growth factors
Basal media
Sugar, amino acids
Growth factors(incl. in FBS)
Inexpensive Expensive
$0/L⇒Clean meat at $6/kg
Growth factors
Liver cellsMuscle cells
Growth
factors
No externally added
FBS & growth factors
*
*
“Culnet System” grows variety of cells without added growth factors
Liver cells Muscle stem cell Placental cells
Co
nve
nti
on
al
“C
uln
et
Sys
tem”
”Culnet System"
Cell c
ou
nt
(rati
o)
□Liver cells
■Pancreas cells
■Ovary cells
*p<0.01, **p<0.05
✅Not limited to muscle
✅No added growth factors
✅Scalable(Flow-based)
Proof of
Concept
“Culnet System” proof of concept
Clean chicken foie gras
9
Cosmetics market
“Early adopters”
✅Contamination free
✅Animal cruelty free
✅Can use human cells
✅Already gaining traction
Youth Elderly
High-end
Low-end
$1.5B market
capitalization
(Japan)
“Customizable Cellular Cosmetics”
EGF
HGF
VEGF
etc.
Product roadmap: Volume & price projection
2020 2023 2026
120,000
120
1.2
Annual volume(t)
〰〰〰
〰〰〰
〰〰〰
〰〰〰
~100kg/month Plant. for cellular cosmetics ingredients
100t/week Plant. High-end meat,“Designer meat”*
10
~10t/month Plant. for health food and supplements
*New meat designed through cell culture technology, i.e. “fish-fat healthy Kobe beef”
Integriculture Inc. Projection
Comp-
lete
In
progress
2018.03
Seed round
Strategic
CVC round?
~$3M
2019.12
Series A
First product
in market
2021.08
Series B
Break
even
~$12M ~$60M
Meat, test
production
Yuki Hanyu, CEO
Chemistry, Systems
EngineeringPh.D (Chemistry)
2010 Oxford University
Keita Fukumoto, CTO
Molecular Biology
Ph.D (Medicine)
2017 Uni. of Hiroshima
Ikko Kawashima, Senior Advisor
Regenerative medicine,
Cellular biologyPh.D(Agronomy)
2012 University of Hiroshima
Yusuke Shinozawa
External Advisor
Leave-a-Nest Inc., Real-Tech Fund
Ryutaro Mori, Business Director
Marketing, Biz.Development
BA (Dev. Economics)
2015 UCLA
Experienced Members Lead the Team
12