Editorials

M. Akram, A. Hamid, A. Khalil, A. Ghaffar, N. Tayyaba, A. Saeed, M. Ali and A. Naveed. Review on medicinal uses, pharmacological, phytochemistry and immunomodulatory activity of plants...................................................................................

G. Tchernev, J.C. Cardoso, A.A. Chokoeva, S.B. Verma, C. Tana, J. Ananiev, M. Gulubova, S. Philipov, N. Kanazawa, P. Nenoff, T. Lotti and U. Wollina. The “mystery” of cutaneous sarcoidosis: facts and controversies..........................................

Frydas and P. Conti. Impact of mast cells on multiple sclerosis: inhibitory effect of natalizumab.................................................

Original articles

M. Athanassiou-Papaefthymiou, O. Shkeir, D. Kim, V. Divi, M. Matossian, J.H. Owen, M.J. Czerwinski, P. Papagerakis, J. McHugh, C.R. Bradford, T.E. Carey, G.T. Wolf, M.E. Prince and S. Papagerakis. Evaluation of CD44 variant expression

V. Arcoraci, L. Santoni, R. Ferrara, G. Furneri, A. Cannata, J. Sultana, S. Moretti, A. Di Luccio, D.U. Tari, C. Pagliaro, S. Corrao and M. Tari. Effect of an educational program in primary care: the case of lipid control in cardio-cerebrovascular prevention...........................................................................................................................................................................................

R. Imberti, A. Ferrigno, A. Tartaglia, V. Rizzo, P. Richelmi and M. Vairetti. Changes in extra- and intracellular pH in hepatocytes exposed to gabexate mesilate..........................................................................................................................................

P. Pavone, V. Rapisarda, A. Serra, F. Nicita, A. Spalice, E. Parano, R. Rizzo, L. Maiolino, P. Di Mauro, G. Vitaliti, A. Pediatric autoimmune neuropsychiatric disorder associated with group

A streptococcal infection: the role of surgical treatment...................................................................................................................

F. Molinari, and W. Liboni. Ozone autohemotherapy induces long-term cerebral metabolic changes in multiple sclerosis patients.................................................................................................

M. Paradisi, F. Alviano, S. Pirondi, G. Lanzoni, M. Fernandez, G. Lizzo, L. Giardino, A. Giuliani, R. Costa, C. Marchionni, L. Bonsi and L. Calzà. Human mesenchymal stem cells produce bioactive neurotrophic factors: source, individual variability and differentiation issues....................................................................................................................................................................

A. Ardizzoni, B. Posteraro, M.C. Baschieri, F. Bugli, A. Sáez-Rosòn, L. Manca, M. Cacaci, F. Paroni Sterbini, C. De Waure, M.J. Sevilla, S. Peppoloni, M. Sanguinetti, M.D. Moragues and E. Blasi. An antibody reactivity-based assay for diagnosis of invasive Candidiasis using protein array........................................................................................................................

L.S. Namazova-Baranova, A.A. Alekseeva, S.M. Kharit, T.N. Kozhevnikova, T.E. Taranushenko, I.A. Tuzankina and F. Scarci.

Letters to the Editor

E. Azarsiz, N.E.Karaca, N.C. Gunaydin, N. Gulez, C. Ozturk, G. Aksu, F. Genel and N. Kutukculer. Do elevated serum IgM levels have to be included in probable diagnosis criteria of patients with ataxia-telangiectasia?..............................................

M. Proietta, S. Ferrero, L. Ferri, N. Cifani, G. Bruno and F. Del Porto. R............................................................................................................

M. Iantorno, U. Campia, N. Di Daniele, S. Nisticò, G.B. Forleo, C. Cardillo and M. Tesauro. Gut hormones and endothelial dysfunction in patients with obesity and diabetes..............................................................................................................................

L. Memè, A. Santarelli, G. Marzo, M. Emanuelli, P.F. Nocini, D. Bertossi, A. Putignano, M. Dioguardi, L. Lo Muzio and F. Bambini. Novel hydroxyapatite biomaterial covalently linked to raloxifene................................................................................

S. Caporuscio, G. Pranteda, S. Nisticò, T. Maucione, M. Canzoni, A. Stefani, M. Muscianese, M. Fantò and M. Sorgi. An

A.M. Zicari, R. Cutrera, F. Occasi, M.P. Carbone, A. Cesoni Marcelli, G. De Castro, L. Indinnimeo, G. Tancredi, R. Galandrini, A. Giuffrida and M. Duse. Serum resistin levels in children with primary snoring....................................................

A. Nigro, A. Nicastro and R. Trodella. Retrospective observational study to investigate Sinerga, a multifactorial nutritional product, and bacterial extracts in the prevention of recurrent respiratory infections in children.......................................................

M. Zapparoli, A.R. Trolese, A. Remo, S. Sina, A. Bonetti and C. Micheletto. Subglotic malt-lymphoma of the larynx: an unusual presentation of chronic cough................................................................................................................................................

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGYVolume 27, No. 3, July-September, 2014

CONTENTS

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INSTRUCTIONS FOR CONTRIBUTORS

International Journal of Immunopathology and Pharmacology is a peer-reviewed journal published every three months. The journal publishes original papers describing research in the fields of immunology, pathology, pharmacology and general experimental and clinical medicine related to inflammation. The intention is that the journal should reflect both the experimental and clinical aspects of immunology as well as advances in the understanding of the pathology and pharmacology of the immune system.Only articles written in English will be published. The scientific standard is the only criterion for accepting a manuscript for publication. The style should be clear and concise. Excessive use of jargon or unusual abbreviations should be avoided. Contributors must send an electronic copy (e-mail: piocontieditor@yahoo.it) of the text, tables and figures, and it is essential that they retain one copy of the original manuscript as the Editor does not accept responsibility for loss of papers submitted. Papers are accepted on the understanding that no substantial part has been, or will be published elsewhere, and once they have been accepted they remain the copyright of the journal. Authors will be charged Euro 97.00/page for the first 5 printed pages and Euro 25.00 for each subsequent page. Payment may be in the form of a money order, credit card (VISA/Master Card) or personal cheque made out to: BIOLIFE, s.a.s., Banca Popolare dell’Adriatico, Via Chieti, 65100 Pescara, Italy; Account n. 101024E (IBAN: IT70 Y 0574815400 07400101024E; BIC: POADIT3PXXX).Preparation of the text: Manuscripts should be sent in a Word file (double spacing) using Times New Roman 12 characters, with 30 mm margins all around, names and postal addresses of the authors, together with the affiliations. Authors’ first names should be initialized. For indexing purposes a small number of key words should be supplied.Generally, papers should be divided into the following parts and in the order indicated: (1) Summary: about 5% of the length of the paper; (2) Introduction: containing the reason for doing the work; (3) Materials and Methods: sufficient information must be included to permit repetition of the experimental work; (4) Results: these should be given concisely together with tables and figures that have clear legends; (5) Discussion: the presentation of results should be separate from a discussion of their significance; the section should not repeat Results; (6) Acknowledgements if any; (7) References: these should be cited in the text by a number in parentheses and listed at the end of the paper in numerical order. Note the following style for journal and book citations:

1. Shotton DM. Elastase. Methods Enzymol 1970; 19:113-40.2. Balo J, Banga J. The elastolytic activity of pancreatic extracts. Biochem J 1950; 46:384-87.3. Frosco MB, Fahed T, Chase J, Macmillan JD. Inhibition of Aspergillus fumigatus elastase with monoclonal

antibodies produced by using denatured elastase as an immunogen. Immun 1992; 60:735-41.When there are more than eight authors, only the first three should be cited with et al.Abbreviation of titles of Journals should follow the list of journals indexed in INDEX MEDICUS. References to books should include the editor(s), publisher and place of publication. Authors are responsible for the accuracy of their references.All authors are required to send a No conflict of interest statement.Illustrations: The Journal recognizes the adoption of the SI unit system. All tables and figures should be cited in order in the text, using Roman numerals for the tables and Arabic numerals for figures. Tables should have a short title. Figures can be send on a separate PDF or jpg file bearing the first author’s name.Proof-reading: Page proofs will be submitted to the contributors for minor corrections and should be returned to the Editor within three days. Major alterations to the text cannot be accepted.Editorial correspondence: All manuscripts, letters to the Editor, and any correspondence regarding Editorial matters, including advertising, back numbers and requests for reprints, should be sent to the Editor-in-Chief: Dr Pio Conti, Professor of Immunology, Postgraduate Medical School, University Zone, viale Unità d’Italia 73, 66100, Chieti, Italy. Tel./Fax +39 0871 574136; e-mails: piocontieditor@yahoo.it or biolife_sas@yahoo.it Website: www.biolifesas.org

Information concerning personal subscription rates, business matters, advertisement and back numbers should be sent to: BIOLIFE, s.a.s viale Unità d’Italia 73, 66100, Chieti, Italy (e-mail: biolife_sas@yahoo.it). Manuscripts should be sent to the Editor-in-Chief: Dr Pio Conti, Professor of Immunology, Postgraduate Medical School, University Zone, viale Unità d’Italia 73, 66100, Chieti, Italy. Tel./Fax +39 0871 574136; e-mail: piocontieditor@yahoo.it or biolife_sas@yahoo.it Website: www.biolifesas.org