Intravenous Parenteral Therapy Lecture

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    INTRAVENOUS PARENTERAL THERAPY

    Definition

    Intravenous (IV) therapy is the insertion of needle or catheter / cannula into a vein, based

    on the physicians written prescription. The needle or catheter/cannula is attached to steriletubing and a fluid container to provide medication and fluids.

    Philosophy

    Historical background of IV Therapy

    The record history of i.v. therapy began in 1492 when a blood transfusion from two

    Romans to the dying Pope Innocent was attempted. All three died.

    In 1628, Sir William Harveys discovery of the blood circulatory system formed the basis

    for more scientific experimentation. In 1658 Sir Christopher Wren predicted the possibility of

    introducing medication directly into the bloodstream, although it was Dr. Robert Boyle who used

    a quill and bladder to inject opium into a dog 1659, with J D Major succeeding with the first

    injection into human in 1665.

    A 15 year old Parisian boy successfully received a transfusion of lambs blood in 1667.

    However, subsequent animal to human transfusions proved fatal and eventually, in 1687, the

    practice was made illegal.

    In 1834, James Bludell proved that only human blood was suitable for transfusion, and

    later the century Pastuer and Lister stressed the necessity for sepsis during infusion procedures.

    In 1900 Karl Landsteiner led the way in identifying and classifying different blood

    groups, and in 1914 it was recognized that sodium citrate prevented clotting which opened the

    gate for the extensive use of blood transfusions.

    Intravenous therapy was being used widely during World War II, and by the mid-1950s

    was being used mainly for the purposes of major surgery and rehydration only. Few medications

    were given via i.v. route, with antibiotics more commonly being given intramuscularly.

    Through the 1960s and 1970s, intermittent medications, filters, electronic infusion

    control devices and smaller plastic cannulae became available. Use of multiple electrolyte

    solutions and medications increased along with blood component therapy, and numerous i.v.

    drugs and antibiotics were being added to i.v. regimens.

    The use of i.v. therapy has expanded dramatically over the last 35 years. This expansion

    continues to accelerate and can be attributed to the following factors:

    The understanding of hazards and complication

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    Improvement in i.v. equipment

    Increased knowledge of physiological requirements

    Increased knowledge of pharmacological and therapeutic implications

    Increased availability of nutrients and drugs in i.v. solutions

    Changes in the traditional roles of doctors and nurses, allowing nurses to develop

    skills that were traditionally the remit of the medical profession (e.g. insertion of

    central venous access devices).

    Here in the Philippines, the Nursing Standards on Intravenous Practice was established

    in 1993 as a guide for those who are and will be practicing intravenous therapy. During the first

    months after the promulgation of the professional regulations Commission (PRC), Board of

    Nursing (BON) Resolution No. 08 series, February 4, 1994, the maiden issues (First Edition) of

    the Intravenous Standards on Intravenous Therapy was printed and circulated. It was first used in

    Cagayan de Oro City where the Training for Trainers was conducted last June 9-11, 1994, after

    the ANSAP Board Members and Advisers had undergone the Training for trainers at Philippine

    Heart Center on October 1993.

    Subsequently, another revision was required to incorporate the PRC-BONs protocol of

    May 17, 1995. Because of the new concept and evolving technology, more revisions were

    deemed necessary. Revisions were made by a special committee of the Association of Nursing

    Service Administrators of the Philippines, Inc. (ANSAP) in collaboration with the PRC-BON, to

    ensure a safe and quality nursing practice in Intravenous therapy in 2002. The new Nursing Law

    RA 9173 has stated that the administration of parenteral injection is in the scope of nursing

    practice. ANSAP believes that the certification of IV Therapist will be continued for several

    reasons, paramount of which is safe nursing practice.

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    Standard and competencies of IV therapy

    Standard Operating Policies and Procedure are established to ensure safe IV therapy

    practice, to protect the patients by maximizing benefits and minimizing risks associated with IV

    therapy and to protect the practice of registered professional IV therapy nurses. The IV therapy

    policies and procedures are written and continuously updated and reviewed as necessary.

    1. Key points prior to initiation of IV therapy

    a. Physicians prescribed treatment. The initiation of intravenous therapy is upon the

    written prescription of a licensed physician which is checked for the following:

    Patients Name

    Type and amount of solution

    The flow rate

    The type, dose and frequency of medication to be incorporated/pushed.

    Others affecting the procedure (x-rays, treatment to the extremities, etc)

    b. Patient Assessment

    Factors to consider for IV therapy

    Clinical status of patient

    Patients diagnosis

    Patients age

    Dominant arm ( non)

    Condition of vein/ skin

    Cannula size

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    Type of solution

    Duration of therapy

    c. IV set and equipment preparation

    Check for expiration date

    Check for clarity; any presence of holes on plastic cover (packaging);

    plastic container (bag) for presence of sediments or insects.

    Check label against the physicians written prescription

    Label for any medication that are added: date, time, dose of medication

    and amount; compatibility of drug with the solution.

    Functionality of infusion pump, patient controlled analgesia (PCA)

    d. Medications

    Nurses administering IV therapy should have knowledge on all

    medications administered including dosages, drug interaction and possible

    clinical effects on the vascular system.

    10 GOLDEN RULES FOR ADMINISTERING DRUGS SAFELY

    1. Administer the right drug.

    2. Administer the right drug to the right patient.

    3. Administer the right dose.

    4. Administer the right drug by the right route.

    5. Administer the right drug at the time.

    6. Document each drug you administer.

    7. Teach your patient about the drug he is receiving.

    8. Take a complete patient drug history.

    9. Find out if patient has drug allergies.

    10. Be aware of potential drug drug or drug-food interactions.

    Nursing 88 Vol. 18, August 1988

    Cathleen McGovern, RN

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    Quality assuance Coordinator

    Edge Water Hospital

    Chicago, Illinois, USA

    2. Competency

    a. Hand washing

    b. Assessing of vital signs

    c. Standard precautions

    d. Principles of aseptic technique

    e. Medication calculation

    f. Medication administration

    ANATOMY AND PHYSIOLOGY

    Superficial veins of the upper limbs are usually selected for peripheral cannulation.

    Cannulation of the lower limbs is associated with an increased risk of venous thromboembolism.

    The wall of a vein is composed of three layers (Figure 1):

    The tunica adventitia (the outer layer): a fibrous layer of connective tissue, collagen and

    nerve fibers which surrounds and supports the vessel.

    The tunica media (the middle layer): a muscular layer containing elastic tissue and

    smooth muscle fibers.

    The tunica intima (the inner layer): a thin layer of endothelium, which facilitates blood

    flow and prevents adherence of blood cells to the vessel wall. Trauma to the endothelium

    encourages platelet adherence and thrombus formation.

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    Figure 1. blood vessel structure.

    Skin is composed of two main layers:

    Epidermis (skin surface): approximately 1mm thick containing sensory nerve endings.

    Dermis (beneath the epidermis): thicker than the epidermis, composed of collagenous and

    elastic connective tissue and containing fat, blood and lymph vessels, nerves, hairfollicles, sweat glands and sebaceous glands.

    Ageing alters the structure and appearance of the skin. The dermal layers become thinner andthere is less subcutaneous tissue to support the blood vessels. The veins of older people are often

    easier to see because of the reduction in subcutaneous tissue, particularly on the dorsum of the

    hand. The vessels are also more mobile, more fragile and often tortuous and thrombosed. Thedorsum of the hand should be avoided in older people.

    Vein selection

    Digital veins of the fingers are small and rarely used. The metacarpal veins and the dorsal venousarch are easily visualized and palpated. The radial end of the dorsal venous arch continues to

    form the cephalic vein while the ulnar end of the dorsal venous arch forms the basilic vein; all ofthese are suitable for cannulation (Figure 2).

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    Figure 2.

    The cephalic and basilic veins continue into the forearm. The basilic vein is often

    overlooked because it is inconspicuous, not easy to stabilize and can be difficult to access due to

    its location. However, the cephalic vein is large, easily stabilized and accessible (Figure 3).

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    Figure 3.

    The median cubital vein runs diagonally across the antecubital fossa connecting the

    basilic and the cephalic veins. There is great variation in the pattern of veins in this area. Themedian cubital vein is absent in 20 percent of the population (Moore and Dalley 1999). The

    veins of the antecubital fossa are usually easily visualized, palpated and accessed because of

    their superficial nature and size. However, their position over the flexor surface of the elbowmakes these veins prone to mechanical phlebitis, and the cannula prone to failure from kinking

    or dislodgement.History taking and assessment should alert nursing staff to specific patient issues that

    should be considered when identifying a site for cannulation. A cannula should not be placed in

    areas of localized edema, dermatitis, cellulitis, arteriovenous fistulae, wounds, skin grafts,

    fractures, stroke, planned limb surgery and previous cannulation. Discussion with the patient is

    important. The patient may prefer the non-dominant limb to be selected for cannulation toremote independence and comfort. Both upper limbs should be inspected to identify possible

    veins for cannulation. Potential veins can then be palpated to assess their condition. An ideal

    vein is soft and bouncy when palpated. Veins that are tender, thrombosed or hard should beavoided. Veins contain valves, crescent shaped folds of endothelium, which assist blood flow

    back to the heart. Valves are most plentiful in the veins of the limbs and occur more frequently at

    junctions where veins converge. Careful observation may reveal valves (small bulges) within theperipheral veins, which should be confirmed by palpation. Valves may prevent blood withdrawal

    and cannula advancement and, therefore, should be avoided. Palpation also allows the

    practitioner to differentiate between arteries and veins. Arteries are pulsatile and should becarefully avoided. New cannulae should be sited proximal to any previous sites to prevent drug

    or fluid infusion through damaged veins.

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    Cannulation procedure

    Position the patient comfortably. It may be helpful to support his or her arm on a pillow.

    Wash hands and apply non-sterile gloves (Centers for Disease Control and Prevention(CDC) 2002).

    Apply a tourniquet to the upper limb to improve venous filling. This should not obstruct

    arterial blood flow and the radial pulse should still be palpable. Ask the patient to open and close the fist to promote venous filling.

    Clean the skin with a chlorhexidine-based solution and allow to dry.

    Do not re-palpate the skin.

    Open the cannula carefully and ensure the stylet within the cannula is positioned with thebevel uppermost.

    Hold the patients arm or hand and use your thumb to pull the skin taut below the

    intended puncture site. This will stabilize and anchor the vein before cannulation.

    Hold the cannula in line with the vein at a 10-30 angle to the skin and insert the cannulathrough the skin.

    As the cannula enters the vein blood will be seen in the flashback chamber. Lower the

    cannula slightly to ensure it enters the lumen of the vein and does not puncture theposterior wall of the vessel.

    Withdraw the stylet slightly and blood should be seen to enter the cannula: this confirms

    the position in the vein. The stylet must not be re-inserted as this can damage the cannula,

    resulting in catheter embolus.

    Slowly advance the cannula into the vein, ensuring the vein remains anchored throughout

    the procedure.

    Release the tourniquet.

    Dispose of the stylet in the sharps container at the bedside.

    Flush the cannula to check patency and to ensure easy administration without pain,resistance or localized swelling.

    Secure the cannula with a moisture-permeable transparent dressing (Royal College ofNursing (RCN) 2003. The dressing should allow viewing of the entry site while firmly

    stabilizing the cannula to prevent mechanical phlebitis or cannula dislodgement.

    Record the cannulation procedure in the patients notes, including device, gauge,

    location, nurses signature and number of insertion attempts.

    FLUID AND ELECTROLYTE THERAPY

    Types of therapy

    1. Maintenance therapy

    Provides water, electrolytes, glucose, vitamins, and in some instances protein to

    meet daily requirements.

    2. Restoration of deficits

    In addition to maintenance therapy, fluid and electrolytes are added to replaceprevious losses.

    3. Replacement therapy

    Infusions to replace current losses in fluid and electrolytes.

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    Types of intravenous fluids

    1. Isotonic solutionsa. Fluids that approximate the osmolarity (280-300 mOsm/L) of normal blood plasma.

    Sodium Chloride (0.9%) - Normal Saline

    Indications: Extracellular fluid replacement when Cl- loss is equal to or greater the Na

    loss.

    Treatment of matebolic alkalosis.

    Na depletion

    Initiating and terminating blood transfusions.

    Possible side effects:

    Hypernatremia

    Acidosis

    Hypokalemia

    Circulatory overload.

    b. Five percent dextrose in water (D5W).

    Provides calories for energy, sparring body protein and preventing ketosis resultingfrom fat breakdown.

    Indications:

    Dehydration

    Hypernatremia

    Drug administration

    Possible side effects:

    Hypokalemia

    Osmotic diuresis dehydration

    Transient hyperinsulinism Water intoxication.

    c. Five percent dextrose in normal saline (D5NS).

    Prevents ketone formation and loss of potassium and intracellular water.Indications:

    Hypovolemic shock temporary measure.

    Burns

    Acute adrenocortical insufiency.

    Possible side effects:

    Hypernatremia

    Acidosis

    Hypokalemia Circulatory overload

    d. Isotonic multiple-electrolyte fluids.

    Used for replacement therapy; ionic composition approximates blood plasma.

    Types:a. Plasmanate

    b. Polysol

    c. Lactated Ringers

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    Indications:

    Vomiting

    Diarrhea

    Excessive diuresis

    Burns

    Possible side effects: Circulatory overload.

    Lactated Ringers is contraindicated in severe metabolic acidosis and/or alkalosis

    and liver disease.

    Hypernatremia

    Acidosis

    Hypokalemia2. Hypertonic solutions

    Fluids with an osmolarity much higher than 310 mOsm (+ 50 mOsm); increase osmotic

    pressure of blood plasma, thereby drawing fluid from cells.

    a. Ten percent dextrose in normal saline

    Administered in large vein to dilute and prevent venous trauma.Indications:

    Nutrition

    Replenish Na and Cl.Possible side effects:

    Hypernatremia (excess Na)

    Acidosis (excess Cl)

    Circulatory overload.b. Sodium Chloride solutions, 3% and 5%

    Indications: Slow administration essential to prevent overload (100 mL/hr)

    Water intoxication

    Severe sodium depletion

    3. Hypotonic solutionsFluids whose osmolarity is significantly less than that of blood plasma (-50 mOsm);

    these fluids lower plasma osmotic pressure, causing fluid to enter cells.

    a. 0.45% sodium chlorideUsed for replacement when requirement for Na use is questionable.

    b. 2.5% dextrose in 0.45% saline, also 5% in 0.2 % NaCl

    Common rehydrating solution.

    Indications: Fluid replacement when some Na replacement is also necessary.

    Encourage diuresis in clients who are dehydrated.

    Evaluate kidney status before instituting electrolyte infusions.Possible side effects:

    Hypernatremia

    Circulatory overload

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    Used with caution in clients who are edematous, appropriate electrolytes should be

    given to avoid hypokalemia.

    Table of Commonly Used IV SolutionsName of

    Solution

    Type of Solution Ingredients in

    1-Liter

    Uses Complications

    0.45% Sodium

    Chloride

    Shorthand

    Notation:

    NS

    Hypotonic

    pH 5.6

    77 mEq Sodium

    77 mEq Chloride

    hypotonic hydration; replace

    sodium and chloride;

    hyperosmolar diabetes

    If too much is mixed with blood cells

    during transfusions, the cells will pull wat

    into them and rupture

    0.9% Sodium

    Chloride

    Shorthand

    Notation:

    NS

    Isotonic

    pH 5.7

    154 mEq Sodium

    154 mEq Chloride

    isotonic hydration; replace

    sodium and chloride;

    alkalosis; blood transfusions(will not hemolyze bloodcells)

    None known

    3% Sodium

    Chloride

    Hypertonic

    pH 5.0

    513 mEq Sodium

    513 mEq Chloride

    symptomatic hyponatremia

    due toexcessive sweating,vomiting, renal impairment,

    and excessive water intake

    rapid or continuous infusion can result in

    hypernatremia or

    hyperchloremia5% Sodium

    Chloride

    Hypertonic

    pH 5.8

    855 mEq Sodium

    855 mEq Chloride

    5% Dextrose inWater

    Shorthand

    Notation:

    D5W

    Isotonic

    pH 5.0

    5 grams dextrose

    (170 calories/liter)

    isotonic hydration; providessome calories

    water intoxication and dilution of bodys

    electrolytes with long, continuous infusion

    10% Dextrose

    in Water

    Shorthand

    Notation:

    D10W

    Hypertonic

    pH 4.3

    10 grams dextrose

    (340 calories/liter)

    may be infused peripherally;

    hypertonic hydration;

    provides some calories

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    5% Dextrose in

    1/4 Strength (or

    0.25%) Saline

    Shorthand

    Notation:

    D5N

    Hypertonic

    pH 4.4

    5 grams Dextrose

    34 mEq Sodium

    34 mEq Chloride

    fluid replacement;replacement of sodium,

    chloride and some calories

    vein irritation because of acidic pH, caus

    agglomeration (clustering) if used with

    blood transfusions; hyperglycemia withrapid infusion leading to osmotic diuresi

    5% Dextrose in

    0.45 Sodium

    Chloride

    Shorthand

    Notation:

    D5NS

    Hypertonic

    pH 4.4

    5 grams Dextrose

    77 mEq Sodium

    77 mEq Chloride

    hypertonic fluid replacement;replace sodium, chloride, and

    some calories

    5% Dextrose in

    Normal Saline

    Shorthand

    Notation:

    D5NS

    Hypertonic

    pH 4.4

    5 grams Dextrose

    154 mEq Sodium

    154 mEq Chloride

    hypertonic fluid replacement;

    replace sodium, chloride and

    some calories

    Ringers

    Injection,

    U.S.P.

    Isotonic

    pH 5.8

    147 mEq Sodium

    4 mEq Potassium

    4 mEq Calcium

    155 mEq Chloride

    electrolyte replacement;

    hydration; often used to

    replace extracellular fluid

    losses

    rapid administration leads to excessive

    introduction of electrolytes and leads to

    fluid overload and congestive conditions;

    provides no calories and is not an adequat

    maintenance solution if abnormal fluid

    losses are present

    LactatedRingers

    Shorthand

    Notation:

    LR

    Isotonic

    pH 6.6

    130 mEq Sodium

    4 mEq Potassium

    3 mEq Calcium

    109 mEq Chloride

    28 mEq Sodium Lactate

    (provides 9

    calories/liter)

    isotonic hydration; replaceelectrolytes and extra-

    cellular fluid losses; mild to

    moderate acidosis (the lactate

    is metabolized into

    bicarbonate which

    counteracts the acidosis)

    not enough electrolytes for maintenance;

    patients with hepatic disease have trouble

    metabolizing the lactate; do not use if lacti

    acidosis is present

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    5% Dextrose in

    Lactated

    Ringers

    Injection

    Shorthand

    Notation:

    D5LR

    Hypertonic

    pH 4.9

    5 grams Dextrose

    (170 calories/liter)

    130 mEq Sodium

    4 mEq Potassium

    3 mEq Calcium

    109 mEq Chloride

    28 mEq Sodium Lactate

    (provides 9

    calories/liter)

    hypertonic hydration;provides some calories;

    replace electrolytes and

    extra-

    cellular fluid losses; mild to

    moderate acidosis (the lactate

    is metabolized intobicarbonate which

    counteracts the acidosis), the

    dextrose minimizes glycogen

    depletion

    VENIPUNCTURE TECHNIQUE

    Methods of vein entry

    There are different methods of vein entry for needles or over needle catheters; indirect, direct,

    direct, and bevel position either up or down. Use of over the needle cannula requires a different

    threading technique than a wing tip or scalp vein needle. With the wing tip usually use the bevel

    down position.

    The Bevel

    The bevel up method usually causes fewer traumas to the vein and is less painful for the

    patient; however, sometimes the bevel down position is better. If the needle and vein are

    approximately the same diameter, this position is likely to perforate the opposite wall of the vein

    on insertion causing a hematoma. This problem is less likely to occur in the bevel down position.

    Entering a vein successfully doesnt guarantee that the vein wont collapse and block the bevel

    when removing the tourniquet. In that case, manipulating the needle slight within the vein may

    relieve the blockage. A greater risk of perforating the opposite wall of the vein when the needles

    bevel is facing up. It is a good idea when entering a small vein with a large bore needle to use the

    bevel down position.

    Remember, a needle that is properly placed in the vein can be palpated. If not, probably it has

    gone through the vein. Remove the needle promptly and reinsert.

    Indirect method

    The first movement, penetrate the skin at a 54 degree angle to side of the vein about

    below the point of the venipuncture, then decrease the needle angle until the is almost parallel to

    the skin surface.

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    The second movement , penetrate the vessel wall and advance the needle cautiously while

    lifting the vein with slight upward pressure. Watch for the backflow to confirm proper placement

    of the needle/catheter. If using the catheter, over the needle, advance the catheter while removing

    the needle. Never reinsert the needle into the catheter which may cause shearing off of the tip of

    the catheter leading to catheter embolus. Since the needle protrudes further than the catheter,

    need to be sure that the catheter itself is in the vein, not just the needle.

    Direct method

    In the direct method the needle is at 30 degree angle over the vein and is inserted in the

    direction of the blood flow. The vein is penetrated in one movement by approaching the vessel

    from the top or side. This method of venipuncture requires considerable more skill then the

    indirect method, but it is less painful for the patient when done correctly.

    When trying to penetrate the skin, be sure to hold the skin taught. This will cause fewer

    trauma and less pain. Before insertion, measure the cannula against the vein to be sure thecannula will clear joints and nodules to ease threading. Some veins have a tendency to roll or

    move away. Pull down on them slight and hold tension for easier penetration. Do not spend too

    much time probing. Gently feel for the tip of the cannula in relation to the vein to give some idea

    if it is below, to the right, or left of the vein. If cannot stabilize the vein or if it disappears,

    remove the cannula and attempt venipuncture in another vein.

    Methods of stabilizing the venipuncture site

    Chevron method

    Using a strip of tape to wide apply sticky side up in a V formation.Apply a piece of 1 tape across the two wings of the chevron. The loop the tubing and secure it

    with another piece of 1 tape. This method can be used with both plastic cannula/ catheter and

    wingtip needle.

    U method

    Using a strip of tape to wide place with a sticky side up under the hub

    folding each tape tail over each corresponding wing in the U formation. Use this method with

    wingtip needle.

    H method

    Place one strip of 1 tape over each wing. Then place another piece of 1 tape

    horizontally over the first two forming the letter H. This method is suitable for securing the

    wingtip needle.

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    INTRAVENOUS THERAPY COMPLICATIONS

    1. LOCAL COMPLICATIONS

    a. Infiltration

    b. Extravasation

    c. Thrombosis

    d. Thrombophlebitis

    e. Phlebitis

    2. SYSTEMIC COMPLICATIONS

    a. Embolism

    b. Pulmonary embolism

    c. Air embolism

    d. Catheter embolism

    e. Hematoma

    f. Systemic infection

    g. Speedshock

    h. Circulatory overload

    i. Allergic reaction

    INFILTRATION

    Results when the infusion cannula becomes dislodged from the vein and fluids are

    infused into the surrounding tissues.

    Cause

    Device dislodged from vein or perforated veinSigns & Symptoms

    Increasing edema at the site of the infusion

    Discomfort, burning, pain at site

    Feeling of tightness at site

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    Decreased skin temperature around site

    Blanching at site

    Absent backflow of blood

    Slower flow rate

    Nursing intervention

    Remove the device

    Apply warm soaks to aid absorption

    Elevate the limbNotify the doctor if severe

    Assess circulation

    Restart the infusionDocument the patient's condition and your interventions

    Prevention

    Check the I.V site frequentlyDon't obscure area above site with tape

    Teach the patient to report discomfort, pain, swelling

    EXTRAVASATION

    It occurs when fluids seep out from the lumen of a vessel into the surrounding tissue.

    Causes

    Damage to the posterior wall of the vein

    Occlusion of the vein proximal to the injection site

    Signs & Symptoms

    Swelling

    Discomfort

    Burning

    Tightness

    Coolness in the adjacent skin

    Slow flow rate

    Nursing Interventions

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    Immediately stop the infusion and remove the device

    Elevate the affected limb

    Apply cold compress to decrease edema and pain

    Apply moist heat to facilitate the absorption of fluid at grossly infiltrated sites

    DRUGS ASSOCIATED WITH EXTRAVASATION NECROSIS

    Generic Name Brand Name

    Calcium chloride Various

    Calcium gluconate Various

    Dacarbazine DTIC

    Dactinomycin Cosmogen

    Daunorubicin Cerubidine

    Dopamine Various

    Doxorubicin Adriamycin

    Idarubicin Idamycin

    Mechlorethamine Mustargen

    Mitomycin C Mutamycin

    Plicamycin Mithracin Streptozocin Zanosar

    Teniposide Vumon

    Vancomycin Various

    Vinblastine Velban

    Vincristine Oncovin

    Vinorelbine Navelbine

    THROMBOSIS

    Occurs when blood flow through a vein is obstructed by a local thrombus. Catheter-

    related thrombosis arises as a result of injury to the endothelial cells of the venous wall.

    Cause

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    Injury to endothelial cells of vein wall, allowing platelets to adhere and thrombus form

    Signs & Symptoms

    Painful, reddened, & swollen vein

    Sluggish or stopped I.V flow

    Nursing Interventions

    Remove the device; restart the infusion in the opposite limb if possible

    Apply warm soaksWatch for I.V therapy related infection

    Prevention

    Use proper venipuncture techniques to reduce injury to the vein

    THROMBOPHLEBITIS

    Occurs when thrombosis is accompanied by inflammation. Infusions allowed tocontinue after thrombophlebitis develops will slow and eventually stop, indicating progression

    to an obstructive thrombophlebitis. All thrombotic complications have the associated danger of

    embolism, especially in cases where the thrombus is not well attached to the wall of the vein.

    Signs & Symptoms

    Local tendernessSwelling

    Induration

    A red line detectable above the IV site.

    Recommendations to Reduce the Risk of Thrombotic Complications

    1. Use veins in the upper extremities

    2. Avoid placing catheters over joint flexions

    3. Select veins with adequate blood volume for solution characteristics

    4. Anchor cannulas securely5. Avoid multiple venipunctures

    PHLEBITIS

    inflammation of a vein that may be caused by infection, the mere presence of a foreign

    body (the IV catheter) or the fluids or medication being given.

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    Causes:

    Injury during Venipuncture

    Prolonged use of the same IV site

    irritating./incompatible IV additives

    Use of vein that is too small for the flow rate

    Use of needle size too large for the vein size

    Signs & Symptoms

    Pain

    Vein that is sore, hard, cord like and warm to touch

    Red line above the site

    Signs of infection

    Phlebitis Rating

    0 = No symptoms

    1 = Erythema at site with or without pain2 = pain at site, erythema and/or edema; no streak, no palpable cord

    3 = pain at site, erythema and/or edema; streak present; palpable cord

    4 = pain at site, erythema and/or edema; streak present; palpable cord > 1 inch; purulentdrainage

    Common Medication that can cause Phlebitis

    Phenytoin

    Diazepam

    Erythromycin

    Tetracycline

    Vancomycin

    Amphothericin B

    40 mEq/L or more doses of KCL

    Nursing Interventions

    Upon assessment of phlebitis, removal the needle

    Avoid multiple insertion

    Application of warm compress

    Continuously monitor the patient- vital signs

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    PULMONARY EMBOLISM

    It associated with venous access devices is usually the result of a thrombus that has

    become detached from the wall of the vein. It is carried by the venous circulation to the right side

    of the heart and then into the pulmonary artery.Circulatory and cardiac abnormalities are caused by full or partial obstruction of the

    pulmonary artery, with possible progression to pulmonary hypertension and right-sided heart

    failure.

    AIR EMBOLISM

    Occurs most frequently with the use of central venous access devices. Occur with the

    insertion of an IV catheter, during manipulation of the catheter or catheter site when the device is

    removed, or when IV lines associated with the catheter are disconnected.

    CATHETER EMBOLISM

    This can occur during the insertion of a catheter if appropriate placement techniques are

    not strictly adhered to. The tip of the needle used during the placement of the catheter can shear

    off the tip of the catheter. The catheter tip then becomes a free-floating embolus. This can occurwith both over-the-needle and through-the-needle catheters. If this happens, cardiac

    catheterization may be required to remove the embolus.

    Signs & Symptoms

    Sudden vascular collapse with the hallmark symptoms of cyanosis, hypotension, increased

    venous pressures, and rapid loss of consciousness.Respiratory distress

    Unequal breath sounds

    Weak pulse

    Causes

    Empty solution container

    Solution container empties; next container pushes air down line

    Tubing disconnected from venous access device or I.V bag

    Nursing Interventions

    Discontinue the infusionPlace the patient in Trendelenburg position on his left side to allow air to enter the right atrium

    and disperse through the pulmonary artery.

    Administer oxygenNotify the doctor

    Document the patient's condition and your interventions.

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    HEMATOMA

    Blod accumulation resulting from the infiltration of blood into the tissues at the

    venipuncture site

    Causes::

    Coagulation defects

    Inappropriate use of tourniquet

    Unsuccessful insertion attempts

    Little pressure upon removal of cannula

    Discoloration of the tissue at the IV site

    Nursing Interventions

    Frequent assessment of the site

    Upon insertion, slowly advance the needle to prevent puncturing both vein walls

    Discontinue therapy if with edema

    Apply pressure for at least 5 minutes upon removal

    SYSTEMIC INFECTION

    If bacteria do not remain in one area but spread through the bloodstream, the infection

    is calledsepticemiaand can be rapid and life-threatening. An infected central IV poses a higher

    risk of septicemia, as it can deliver bacteria directly into the central circulation.

    Caused by: Staphylococcuaureus, Klebsiella, Serratia, Pseudomonas Aeruginosa

    Signs & symptoms

    Fever, chills, & malaise for no apparent reason

    Contaminated I.V site, usually with no visible signs of infection at site

    Causes

    Failure to maintain aseptic technique during insertion or site care

    Severe phlebitis, which can set up ideal conditions for organisms growth

    Poor tapingProlonged indwelling time of device

    Immunocompromised patient

    http://en.wikipedia.org/wiki/Septicemiahttp://en.wikipedia.org/wiki/Septicemia
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    Nursing Interventions

    Notify the doctor.Administer medications as prescribed

    Culture the site and the device

    Monitor the patient's vital signsPrevention

    Use scrupulous aseptic techniqueSecure all connections

    Change I.V solutions, tubing and venous access device at recommended times

    Use I.V filters

    Management and Prevention Tips

    Assess catheter site daily

    Accurately document visual inspection and palpation data.

    Refer to physician for any suspected infection.

    Use maximal sterile-barrier precautions during insertion (sterile technique)

    Practice good hand hygiene before and after palpating, inserting, replacing, or

    dressing any intravascular device.

    If any part of the system is disconnected, dont rejoin it

    Remove at first sign of infection

    Replace site, tubings and bags per policy example: change set= 72 hours, TPN

    and single use of antibiotics=24 hrs

    SPEEDSHOCK

    Rapid introduction of a foreign substance, usually a medication, into the circulation.

    Signs & Symptoms

    Flushed face

    Headache

    Tight feeling in the chest

    Irregular pulse

    In extreme cases:

    Loss of consciousness

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    Nursing Interventions

    STOP the infusion

    Careful monitoring of IV flow rate and patient response. Maintain prescribed

    rate.

    Know the actions and side effects of the drug being administered

    Nursing Interventions

    Use of IV pumps when indicated

    Begin infusion of 5% dextrose at a KVO rate in emergency cases

    Evaluate circulatory and neurologic statusNotify the physician

    CIRCULATORY OVERLOAD

    An excess of fluid disrupting homeostasis caused by infusion at a rate greater than the

    patients system is able to accommodate

    Signs & Symptoms

    Shortness of breath

    Elevated blood pressure

    Bounding pulse

    Jugular vein distention

    Increased Respiratory rate

    Edema

    Crackles or rhonchi upon auscultation

    Causes

    Roller clamp loosened to allow run on infusion

    Flow rate too rapid

    Miscalculation of fluid requirements

    Nursing Interventions

    Raise the head of the bed

    Slow the infusion rate

    Administer oxygen as needed

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    Notify the doctor

    Administer medications as ordered

    ALLERGIC REACTION

    Maybe a Local or generalized response to tape, cleansing agent, medication, solutionor intravenous device

    Signs & Symptoms

    SYSTEMIC

    Runny nose

    Tearing

    Bronchospasm

    Wheezing

    Generalized rash

    LOCAL

    Wheal

    Redness

    Itching at the site

    Nursing Interventions

    If reaction occurs, stop the infusion immediately and infuse normal saline

    solution.

    Maintain a patent airway.

    Notify the doctor.

    Administer antihistaminic steroid, anti inflammatory, & antipyretic drugs, as

    ordered.

    Give 0.2 to 0.5ml of aqueous epinephrine subcutaneously. Repeat at 3-minute

    intervals and as needed, as ordered

    FLUID OVERLOAD

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    This occurs when fluids are given at a higher rate or in a larger volume than the system

    can absorb or excrete. Possible consequences includehypertension,heart failure, andpulmonary

    edema.

    INFECTION CONTROL

    Infection at the venipuncture site is usually causd by a break in aseptic technique during

    the procedure. The following measures reduce patients risk:

    Wash hands before starting an IV or before handling any of the IV equipment.

    Use a approved antiseptic ( as per hospitals protocol) to clean the patients skin.

    Cut/ clip the hairs of the venipuncture site if necessary. Do not share.

    http://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Heart_failurehttp://en.wikipedia.org/wiki/Heart_failurehttp://en.wikipedia.org/wiki/Pulmonary_edemahttp://en.wikipedia.org/wiki/Pulmonary_edemahttp://en.wikipedia.org/wiki/Pulmonary_edemahttp://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Heart_failurehttp://en.wikipedia.org/wiki/Pulmonary_edemahttp://en.wikipedia.org/wiki/Pulmonary_edema
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    Documentation of IV therapy

    Proper documentation provides:

    An accurate description of care that can serve as legal protection.

    A mechanism for recording and retrieving information.

    A record for health insurers and retrieving information documenting the insertion of a

    venipuncture devise or the beginning of therapy

    a. The following information of acre that can serve as legal protection:

    Size, type, and length of cannula/needle

    Name of person who inserted the IV catheter

    Date and time of insertion

    b. Label the IV solution specifying:

    Type of IV fluid

    Medication additives and flow rate

    Use of any electronic infusion devise

    Duration of therapy and nurses signature

    c. In additional documentation following information is documented in the patients chart:

    Location of and condition of insertion site

    Complications, patients response and nursing interventions

    Patient teaching and evidence of patient understanding (for example ability to explain

    instruction or perform a return demonstration).

    Signature of nurse

    Other observations

    IV THERAPY PROCEDURE

    A. Setting up

    B. Inserting IV utilizing the dummy arm

    C. Changing an IV solution

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    D. Discontinuing an IV infusion

    Steps

    A. Setting up

    1. Verify written prescription and make IV label

    2. Observe ten (10) Rs when preparing and administering IVF.

    3. Explain procedure to reassure patient and/or significant others, secure consent if necessary.

    4. Assess patients vein; choose appropriate site location, size/ condition.

    5. Do hand hygiene before and after the procedure.

    6. Prepare necessary materials for procedure (IV tray with IV solution, administration set, IV

    cannula, forceps soaked in antiseptic solution, alcohol swabs or cotton balls soaked in alcohol

    with cover (this should be exclusively used for IV), plaster, tourniquet, glove, splint, ad IVhook, sterile 2x2 gauze or transparent dressing.

    7. Check the sterility and integrity of the IV solution, IV set and other devices.

    8. Place IV label on IVF bottle duly signed by RN who prepared it (patients name, room no.,

    solution, drug incorporation, bottle sequence and duration, time and date).

    9. Open the seal of the IV infusion aseptically and disinfect rubber port with cotton ball with

    alcohol.

    10.Open IV administration set aseptically and close the roller clamp and spike the infusate

    container aseptically.

    11. Fill drip chamber to at least half and prime it with IV fluid aseptically.

    12.Expel air bubbles if any and put back the cover to the distal end of the IV set (get ready for

    IV insertion).

    B. Inserting IV utilizing the dummy arm

    1. Verify the written prescription for IV therapy; check prepared IVF and other things needed.

    2. Explain procedure to assure the patient and significant others and observed the 10 Rs.

    3. Do hand hygiene before and after the procedure.

    4. Choose site for IV

    5. Apply tourniquet 5 to 122 cm (2-6 inches) above injection site depending on condition of

    patient.

    6. Check for radial pulse below tourniquet.

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    7. Prepare site with effective topical antiseptic according to hospital policy or cotton balls with

    alcohol in circular motion and allow 30 seconds to dry. ( no touch technique)

    Note: CDC Universal precaution: always wear gloves when doing any venipuncture.

    8. Using the appropriate IV cannula, pierce skin with needle positioned on a 15-30 degree angle.

    9. Upon flashback visualization decrease the angle, advance the catheter and stylet (1/4 inch)

    into the vein, check if tip of catheter can be rotated freely inside the vein...

    10.Position the IV catheter parallel to the skin. Hold stylet stationary and slowly advance the

    catheter until the hub is 1 mm to the puncture site.

    11.Slip sterile gauze under the hub. Release the tourniquet; remove the stylet while applying

    digital pressure over the catheter with one finger about 1-2 inches from the tip of the inserted

    catheter.

    12. Connect the infusion tubing of the prepared IVF aseptically to the IV catheter.

    13. Open the clamp, regulate the flow rate, reassure patient.

    14. Anchor needle firmly in place with the use of:

    a. Transparent tape/ dressing directly on the puncture site.

    b. Tape ( using any appropriate anchoring style)

    c. Band-aid

    15. Tape a small loop of IV tubing for additional anchoring ; apply splint ( if needed)

    16.Calibrate the IVF bottle and regulate flow of infusion according to prescribed duration.

    17. Label on IV tape near the IV site to indicate date of insertion, type and gauze of IV catheter

    and countersign.

    18. Label with plaster on the IV tubing to indicate the date when to change the IV tubing.

    19. Observe patient and report any untoward effect.

    20. Document in the patients chart and endorse to incoming shift.

    21.Discard sharps and waste according to Health Care Waste Management (DOH/ DENR).

    C. Changing an IV solution

    1. Verify doctors prescription in doctors order sheet; countercheck IV label, IV card, infusate

    sequence, type, amount, additives (if any), and duration of infusion.

    2. Observe ten (10) Rs.

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    3. Explain procedure to reassure the patient and significant other and assess IV site for redness,

    swelling, pain and etc.

    4. Change IV tubing and cannula if 48-72 hrs. Has lapsed after IV infusion.

    5. Wash hands before and after the procedure.

    6. Prepare necessary materials; place on IV tray.

    7. Check sterility and integrity of IV solution.

    8. Place IV label on the IV bottle.

    9. Calibrate new IV bottle according to duration of infusion as per prescription.

    10. Open and disinfect rubber port of IV solution to follow.

    11. Close the roller clamp and spike the container aseptically.

    12. Regulate the flow based on the prescribed infusion rate of infusion. Expel air bubbles (if

    any).

    13. Reiterate assurance to patient and significant others.

    14. Discard all waste materials according to health care waste management.

    15. Document and endorse accordingly.

    D. Discontinuing an IV infusion

    1. Verify written doctors order to discontinue IV including IV medicines.

    2. Observe ten (10) Rs.

    3. Assess and inform the patient of the discontinuation of IV infusion and of any medicine.

    4. Prepare the necessary materials; IV tray or injection tray with sterile cotton balls with

    alcohol, plaster, pick-up forceps in antiseptic solution, kidney basin band aid.

    5. Wash hands before and after procedure.

    6. Close the roller clamp of the IV administration set.

    7. Moisten adhesive tapes around the IV catheter with cotton ball with alcohol; remove plastergently.

    8. Use pick-up forceps to get cotton balls with alcohol and without applying pressure, remove

    needle or IV catheter then immediately apply pressure over the venipuncture site.

    9. Inspect IV catheter for completeness.

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    10. Place dressing over the venipuncture site.

    11.Discard all waste materials including the IV cannula according to health care waste

    management (DOH/DENR).

    12. Reassure patient.

    13. Document time of discontinuance, status of insertion site integrity of IV catheter and endorse

    accordingly.