Intro Lab - Anatomy CNS - Drg. Yuni

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    Yuniarti

    Department of anatomy

    Faculty of medicine

    UNISBA

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    Organization of the nervous system

    1.Central Nerve System

    - Brain

    - Spinal cord

    2. Peripheral Nerve System

    - Cranial nerve

    - Spinal nerve

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    Gyri: fold,which greatly increase the surface area of the cortex

    Deepest groove between folds : fissure

    Shallow groove between folds : sulci

    The cerebrum is divided into left and right hemisphere by a longitudinalfissure

    .

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    The longitudinal fissure containsthe sickle-shaped fold of dura mater, the falx

    cerebri, and the anterior cerebral arteries.

    In the depths of the longitudinal fissure,the corpus callosum, connects the

    hemispheres across the midline

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    Each cerebral hemisphere is

    divided into lobes:

    ~The Frontal lobe

    occupies the area anterior to thecentral sulcus and superior to

    the lateral sulcus

    ~The parietal lobe

    occupies the area posterior to the

    central sulcus and superior to thelateral sulcus

    ~The occipital lobe

    occupies the small area behind

    the parieto-occipital sulcus

    ~The temporal lobe

    occupies the area inferior to the

    lateral sulcus

    ~Insula lobe

    Within lateral fissure

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    Insula lobe

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    Central sulcus : separate the frontal lobe from parietal lobe

    Calcarine sulcus : between cuneus & lingual gyrus (Look at medial aspect) Parieto-occipital sulcus : separates the parietal lobe from the occipital lobe

    Lateral sulcus : separates the frontal lobe from the temporal lobe.

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    Internal Structure of the Cerebral Hemispheres

    The cerebral

    hemispheres arecovered with a layer of

    gray matter, the cerebral

    cortex.

    Located in the interiorof the cerebral

    hemispheres are the

    lateral ventricles,

    masses of gray matter,

    the basal nuclei, and

    nerve fibers. The nerve

    fibers are embedded in

    neuroglia and constitute

    the white matter

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    The Cerebral Cortex

    Frontal (Forehead to top)Motor Cortex

    Parietal (Top to rear)Sensory Cortex

    Occipital (Back)Visual Cortex

    Temporal (Above ears)Auditory Cortex

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    The white matter is composed of myelinated nerve fibers ofdifferent diameters supported by neuroglia.

    The nerve fibers may be classified into three groups

    according to their connections:(1) commissural fibers

    (2) association fibers

    (3) projection fibers.

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    1. Commisure fibers

    Commissure fibers essentially connect corresponding regions of

    the two hemispheres.

    They are as follows:

    - the corpus callosum*splenium

    *genu

    *rostrum

    - the anterior commissure

    - the posterior commissure

    - the fornix

    - the habenular commissure.

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    2. Association fibers

    Interconnect cortical regions within the same hemisphere

    (a) Short association fibers

    The short association fibers lie immediately beneath

    the cortex and connect adjacent gyri; these fibers run

    transversely to the long axis of the sulci.

    -

    http://3.bp.blogspot.com/_kaQ5P19FVgk/TVGN_s-LIhI/AAAAAAAAHhg/biiVZtW4SbA/s1600/Uncinate_Fasciculus.JPG
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    (b)Long association fibers

    Link one lobe with another

    The superior longitudinal fasciculus

    The arcuate fasciculus

    The inferior longitudinal fasciculus

    -The uncinate fasciculus

    The cingulum

    The fronto-occipital fasciculus

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    3. Projection fibers

    Contain axonsthat conduct nerveimpulses from the

    cerebrum

    Lower parts of the

    CNS (thalamus,brainstem, spinal

    cord)

    Lower parts of theCNS (thalamus,brainstem, spinal

    cord)

    Cerebrum

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    The cerebellum , the second-largest part of the brain

    The cerebellum is posterior to the medulla and pons & inferior to the

    posterior portion of the cerebrum

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    In superior /inferior views,

    the shape of the cerebellum

    is somewhat like a

    butterfly

    The central constricted

    area is the vermis

    The lateral is cerebellar

    hemispheres

    Lobes :

    - Anterior lobe

    - Posrerior/middle lobe

    - Flocculonodular

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    Primary fissure :

    Separated anterior

    lobe & middle lobe

    Horizontal fissure :Separated superior &

    inferiot surface

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    Have 2 part :- superfisial layercerebellar

    cortex (gray matter)

    - deep layerwhite matter

    .

    The cerebellar cortex has ridges

    called folia.

    The white matter of the medulla

    resembles a branching tree and

    is called the arbor vitae.

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    Cerebellar Peduncles

    The superior cerebellar peduncles connect the cerebellum to the midbrain

    The middle cerebellar peduncles connect the cerebellum to the pons

    The inferior cerebellar peduncles connect the cerebellum to the medulla

    oblongata.

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    Diencephalon isthe part of brain between the brainstem and the

    cerebrum,surround the third ventricle

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    Its main component are:

    -Thalamus

    -Subthalamus

    -Epithalamus

    -Hypothalamus

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    epithalamus

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    The hypothalamus is a small part of the diencephalon located inferior to

    the thalamus

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    Brainstem is the part of the brain between the spinal cord andthe diencephalon

    It consist of three structurally and functionally connected regions :

    1. Medulla oblongata2. Pons

    3. Midbrain

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    The midbrain extends

    From the pons to the

    Diencephalon

    Is about 2,5 cm long

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    The anterior part of the midbrain contains a pair of tract

    called cerebral peduncles

    Cerebral peduncle contain:

    - axon of corticospinal, corticopontine, corticobulbar motor neurons whichconduct nerve impulses from the cerebrum to the spinal cord, medulla

    and pons.

    - axon s of sensory neurons that extend from the medulla to the thalamus

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    The midbrain comprises two lateral halves, called the cerebral peduncles;

    each of these is divided into :

    -an anterior part, the crus cerebri

    -a posterior part, the tegmentum

    by a pigmented band of gray matter, the substantia nigra

    O th l t l t f th idb i

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    On the lateral aspect of the midbrain :

    -The superior brachiumpasses from the superior colliculus to the lateral

    geniculate body and the optic tract.

    - The inferior brachiumconnects the inferior colliculus to the medial geniculate

    body.

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    The posterior part of the midbrain, called the tectum

    Contains four rounded elevations :

    - Two superior elevationssuperior colliculi (visual)

    - Two inferior elevationsinferior colliculi (auditory)

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    RESUME MIDBRAIN CONSIST OF

    1. Cerebral peduncles crus cerebri & tegmentum DIVIDED by apigmented band of gray matter, the substantia nigra

    2. Superior dan inferior brachium

    3.Tectum (2 superior colliculi & 2 inferior colliculi)

    4. Nuclei (red nuclei, substansia nigra, nuclei CN III & CN IV)

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    The pons lies directly superior to the medulla and anterior to the cerebellum

    Is about 2,5 cm long

    Links cerebellum with mesencephalon, diencephalon, cerebrum, and spinal cord

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    The anterior surface is convex from side to side and shows many transverse

    fibers that converge on each side to form the middle cerebellar peduncle

    There is a shallow groove in the midline, the basilar groove, which lodges the

    basilar artery.

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    Nuclei of the pons :

    1. Pontine nuclei

    are the sites at which signals for voluntary movements that originate inthe cerebral cortex are relayed into the cerebellum

    2. Peumotaxic area & Apneustic area

    together with the medullary rhythmicity area help control breathing

    3. Nuclei associated with cranial nerve V(trigeminal),

    VI(abdusent), VII(facial), VIII (vestibulocochlear)

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    Medulla is a continuation of the spinal cord, it forms the inferior part

    of brain stem

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    On the anterior surface of the medulla is the anterior median fissure.

    On each side of the median fissure, there is a swelling called the pyramid.

    The pyramids are composed of bundles of nerve fibers, called corticospinal fibers

    The pyramids taper inferiorly, and it is here that the majority of the descending fibers cross over to the

    opposite side, forming the decussation of the pyramids

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    Posterolateral to the pyramids are the olives, which are oval elevations produced by

    the underlying inferior olivary nuclei.

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    As in the spinal cord, the medulla oblongata consists of white matter and gray matter

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    Nuclei of medulla :

    1. The cardiovascular center

    regulate the rate and force of the heartbeat and the diameter of blood vessels

    2. The medullary rhythmicity arearespiratory center

    3. Inferior olivaryrelay impulses from proprioceptors (monitoring joint &muscle positions)

    to the cerebellum

    4. Gracile & cuneatesensations of touch, conscious proprioception, pressure and vibration

    5. Nuclei that receive sensory input from or provide motor output to

    cranial nerve IX (glossopharyngeal), X (vagus), XI (accesorry) &

    XII (hypoglossal)

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    6. Solitary nucleus- receives

    visceral sensory information

    7 Olivary nuclei

    lateral to pyramids. Receivesensory info from

    proprioceptors (position) in

    skeletal muscles & joints &

    act as a relay point to the

    cerebellum

    8. Non-vital reflex centers

    Vomiting, hiccough,

    swallowing, coughing,

    sneezing

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    The brain is supplied

    by the two internal

    carotid and the two

    vertebral arteries.

    The internal carotid

    arterybegins at the

    bifurcation of the

    common carotid artery

    Enters the subarachnoid

    space by piercing the

    arachnoid mater and turns

    posteriorly to the region of

    the medial end of thelateral cerebral sulcus.

    Here, it divides into the

    anterior and middle

    cerebral arteries

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    The vertebral

    artery

    a branch of thefirst part of the

    subclavian artery

    ascends the neck

    by passing

    through theforamina in the

    trasverse

    processes of the

    upper six cervical

    vertebrae.

    It enters the skull

    through the

    foramen magnum

    The basilar artery

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    The basilar artery

    formed by the union

    of the two vertebral

    arteries, ascends ina groove on the anterior

    surface of the pons.

    At the upper border

    of the pons,

    it divides intothe two posterior

    cerebral arteries.

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    The circle of Willis lies in the

    interpeduncular fossa at the

    base of the brain.

    It is formed by the

    anastomosis between the two

    internal carotid arteries and

    the two vertebral arteries .

    The anterior communicating,

    anterior cerebral, internal

    carotid, posterior

    communicating, posterior

    cerebral, and basilar arteriesall contribute to the circle.

    Circle of Willis

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    Th i l d b i ti ti

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    The spinal cord begin as a continuation

    of the medulla oblongata.

    In adults, 42-45cm in long

    Extend from the foramen magnum in theoccipital bone to the level of the L1 or L2

    Enlarged in two regions :

    1. Cervical enlargment (C4-T1 segment of

    the spinal cord)

    2. Lumbar/lumbosacral enlargment(T11-S1 segment of the spinal cord)

    The medullary cone is tapering inferior end,

    terminate as high as T12 vertebrae or

    as low as L3 vertebrae

    The spinal cord occupies only the superiortwo thirds of the vertebral canal

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    Cauda equina is bundle ofspinal nerve roots

    arising from the lumbosacral enlargment & the

    medullary cone, caudal to the termination

    of the spinal cord resembles a horses tail

    Terminal filum :

    -arising from the tip of the medullary cone,

    descend among the spinal roots

    in the cauda equina

    -an anchor for the inferior end of spinal cord

    and the spinal meninges

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