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Introduction: Developing a Global Collaboration to Study Diet and Non-Communicable Disease Prevention
Connie Weaver, Ph.D.Purdue University
West Lafayette, IN [email protected]
Session- International Breast Cancer and Nutrition: A model for research, training and policy in diet, epigenetics, and chronic disease prevention
Connie Weaver – IBCNAilsa Welch – Diet and Breast Cancer – New ApproachesNahla Hwalla – Diet and Breast Cancer in the Middle
EastSophie Lelièvre – Nutrition and Breast Cell Biology –
New ToolsDorothy Teegarden – Obesity and Energy Metabolism in
Breast Cancer Progression
Purdue University Cooperative Extension Service is an equal access/equal opportunity institution.
http://www.purdue.edu/dp/oncological/ibcn.php
Sophie Lelièvre, Leader, Basic Medical Sciences
Connie M. Weaver, Co-Leader, Nutrition Science
Purdue University Cooperative Extension Service is an equal access/equal opportunity institution.
Genetics
EnvironmentCarcinogens/exposures
Diet
Exercise
Aggressive Breast Cancer
Images, courtesy from Dr. Kurt B. Hodges, IU health)
Normal Breast Cells
10 µm
Nutrition is anchored in cultureLebanon
China
Uruguay
Ghana
Purdue University Cooperative Extension Service is an equal access/equal opportunity institution.
Specific chromatin
alteration
at a define loci
Stem/Progenitor cell theory of the origin of breast cancer
subclasses: This requires measure of epigenetic
changes at single cell level
Joseph Irudayaraj, Agricultural and
Biological Engineering
Research team
• Clinicians
• Researchers (life
sciences)
• Researchers (social
sciences)
• Public Health/Policy
experts
• Nutritionists
Uruguay
USAFrance
Ghana
Japan
C
Lebanon
IBCN NETWORK
GBNL
QT
SW
Purdue University Cooperative Extension Service is an equal access/equal opportunity institution.
Beatrice Wiafe Addai
Breast Surgeon, GhanaSophie Lelièvre
Basic Medical SciencesLaurence GabrielUniversity of Rennes, France
Ellen Gruenbaum
Anthropology
Establishing interdisciplinary teams
Mayor
of
Kumasi
Purdue University Cooperative Extension Service is an equal access/equal opportunity institution.
Ghana
Technologies
Epigenetic Changes
Nutrigenomics Alterations in Gene Expression
Dietary Compounds Type of Breast Cancer
Engineering
Economics
&
Behavior
Studies
Anthropology
Translational
Research
Communication
Population Studies
Public
Policy
International Breast Cancer and Nutrition Project-Organizational Chart
EXTERNAL
ADVISORY
COMMITTEE
Country
Team
DATA
MANAGEMENT &
ARCHIVES
IBCN-WHO-IRAC
COMMITTEE
CORE
COMMITTEE
PR/ ADVERTISEMENT
COMMITTEE
Sample Acquisition
Committee
Epigenome Task Force
Physical Activity &
Psychosocial Factor
Committee
Communication
Committee
Nutrition Committee
International Liaison
Committee
Education Committee
Advocacy Committee
Public Health & Policy
Committee
ETHICS
COMMITTEE PULICATION
COMMITTEE
Executive
Committee
Country
TeamCountry
Team
Country
Team
Country
Team
Country
Team
Country
Team
Country
Team
Annual International Symposia on Nutrition and Breast Cancer
October 16-18, 2014 at Purdue University
Annual Strategic Think Tank Retreatswith Country Partners
Build Infrastructure• Bylaws for interaction• Internal Steering and External Advisory
Committees• Cyberinfrastructure to facilitate integration
of data and workflow• Establish student training reciprocity
Grants• Keck grant• NIH Conference grants• Policy grants• Allen Foundation grant in communication• Training grants in bioethics• Susan G. Komen health breast tissue
biorepository
Publication describing collaboration:Publication describing collaboration:
Lelièvre SA, Weaver CM. Global nutrition research: nutrition and breast cancer prevention as a model. Nutr Rev doi:10.1111/nure.12075 70:1-11, 2013.
