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8/11/2019 Introduction to Health Research for Ayurveda, Siddha and Unani Teachers
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Introduction to
Health Research Methods
&A discussion on issues in
Ayurveda, Siddha and Unani
research
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What we will look into
Basic research methods in todays
practice
The gap between the fundamentals ofA.S.U. and the available research
methods
Required modifications A couple of examples
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Before we enter
The chorus is A.S.U. need to be moreevidence-based
But A.S.U. systems were born out of attemptsof going beyond the body(after perfecting it)
Unchanged concepts (over millenniums) ....
Somewhere got interrupted
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One Word Can SaveYour Life: No! - New
research shows how
some common testsand procedures arent
just expensive, but
can do more harmthan good.
http://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.htmlhttp://www.thedailybeast.com/newsweek/2011/08/14/some-medical-tests-procedures-do-more-harm-than-good.html8/11/2019 Introduction to Health Research for Ayurveda, Siddha and Unani Teachers
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"From the Vedas we learn a
practical art of surgery,
medicine, music, house
building under which
mechanized art is included.They are encyclopedia of
every aspect of life, culture,
religion, science, ethics, law,
cosmology andmeteorology.
William James (18421910)
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Research defined
Research is an organized and systematic
way to find answers to questions
WhatWhen
Why
Where
Who
How
Research is a creative process
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Research what is it all about?
Central to the scientific enquiry.
Seeing what others see and findingwhat others dont.
Purpose: to add to knowledge
that will better the lives of people
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Research is a scientific process
There is a need to demystify the scientific process. Scientific Inquiry is basically a potentiation of common
sense ,which is one of the most equitably distributedhuman gifts.
As Einstein said The whole of science is nothing morethan a refinement of everyday thinking.
In a sense ,most of us conduct some research in our
daily life.(e.g) ,if we want to buy a car in a proper way, wecollect information about the models anddealers,analyse it then try to reach the scientificconclusion on which one to buy.
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Health Research
Healthmost vital part of human life
Health research & Medical research
Cornerstone of all the advancements
Health for all or Millennium
Development Goalsonly through proper
research
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What health research has
achieved so far
Small pox
Rheumatic fever & Rheumatic heart
disease
Iodine deficiency
Tobacco use & cancer
HIV/AIDS SARS/Avian flu/Swine flu
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Is Health Research a luxury?
Should Countries with scarce resources doresearch ?Yes
Because we are a poor country , wecannot afford not to do research .
(Jawaharlal Nehru) Clinical research needed, but with
honest intentions: Harsh Vardhan
Health researchA vital investment
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Research provides the reliableevidence
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Definition of levels of evidence and
grading of recommendation
Level Type of evidence available from Grade
I a Meta-analysis of RCTsA
I b At least one RCT
I I a At least one well-designed controlled study withoutrandomization
BI I b At least one other type of well-designed quasi-
experimental study
III Well-designed non-experimental descriptivestudies
IV Expert committee reports or opinions and/or clinical
experience of respected authoritiesC
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Health research in India
Since more than 2000 years
1911 to 2011 (IRFA to ICMR)
DHR - 2007 For mariginalized communities - priority
Health research in India is poor: The
Lancet * Research to achieve healthcare for all in India
0.4% in 1988 to 1.8% in 2008*The Hindu, 04.04.2011
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Research
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Research in CCRAS
Basic research
Clinical research
Drug research Literature research
New drug development
Collaborative research
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Tools for health research
Epidemiology
Measures of disease frequency
Causations & Associations
Validity & reliability
Study designs etc.,
Biostatistics
Descriptive statistics
Sample size
Tests of significance etc.,
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Types of health research
Basic and applied
Empirical and theoretical
Qualitative and quantitative
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Types of Research Studies
Research studies can be classifiedas:
Wellness typeCausation type
Disease type
Prognosis type
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Choosing a Research Topic
FINER*Feasible
InterestingNovel
Ethical
Relevant* Hulley et al, 2001
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Study designs
1. Different questions require different
types of Study Designs.
2. It is essential to understand the
structure of different Study Designs
3. Choosing the correct study design is
crucial to the success of the Research
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Epidemiologic Study Designs
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Research cycle
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The life cycle of epidemiological
investigations:
The never ending story
Identifying
data needs
Spelling out the
research question
Formulating the
study objectives
Planning the
analysis
Preparing data
collection instruments
Analysing data
Drawing conclusions
Formulating
recommendations
Involving the
programme
Collecting data
Here we
go again
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Research question spells out the local
public health problem
Problem in district Xamong the populationreached levelduring
Note: The statement specifies: What
How much
Who
Where
When
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Good research & Bad research
There is only one type of research - goodresearch .
Bad research does not deserve the name -Research
Badly done research is utter waste of time ,money and effort; it is unethical as it exposesresearch subjects to the inherent risk ofexperimentation with no reward to them ,to
others or communities
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Poor medical research is a
SCANDAL!*
Due to ignorance or willingly!
Fear of Epidemiology / Biostatistics
Unprofessional, unethical & unacceptable
Very common!?
*BMJ, 1994;308:283-284
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Flawed research
A triple waste
Researchers
Participants and the system!
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To lose ones health renders science null,
art inglorious, strength unavailing, wealth
useless and eloquence powerless
Herophilus, 300 BC
Lets take up the challenge &
RESPONSIBILITY!
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Oilbath is the key to good health
Be sure to take oilbath weekly
Oilbath keeps you healthy
Take regular oilbath
Oilbath prevents &cures many ailments
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Hypothetical Research Question
Your mission:
Reduce the incidence of DPN
Your belief:
Regular oilbath is the key to good health
Your hypothesis
Regular exercise decreases the risk of DPN
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Example of a Cross-Sectional Study
Association between regular oilbath and
DPN in the among DM
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Cross-sectional Study
Sample of Population
Oilbath + Oilbath -
Prevalence of
DPN
Prevalence of
DPN
Time Frame = Present
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Cross-sectional Study
Regular oilbath
+ -
D
P
N
+
- 90
10 90
10
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Case-Control Study
Patients with DPN
Patients w/o DPN
PresentPast
Regular OILBATH +
Regular OILBATH +
Regular OILBATH -
Regular OILBATH -
Cases
Controls
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Example of a Case-Control Study
Are those with DPN less likely to haveOILBATH regularly?
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Prospective Cohort Study
Regular
OILBATH -
Regular
OILBATH +
No DPN
DPN
DPN
No DPN
Present Future
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Example of a Cohort Study
To see the effects of regular
OILBATHon DPN in a DM population
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Experimental Studies
Clinical trials provide the gold
standard of determining the
relationship between OILBATHand
prevention of DPN.
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Clinical Trial
Study
Population
Treatment
Group
Control
Group
Outcomes
Outcomes
R
a
n
d
o
m
iz
e
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Clinical Trial
Study
Population
R
a
nd
o
m
iz
e
OILBATH
No OILBATH
DPN
No DPN
DPN
No DPN
E id i l i l St di
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Epidemiological Studies:
Summary
Cross-Sectional
Case-Control
Cohort RCT
Cost + ++ +++ ++++
Duration + ++ +++ +++
SampleSize
Varies Small Large Varies
Incidence,Prevalence
Prevalence None Incidence Incidence
MultipleOutcomes
Yes No Yes Yes
Bias Prone Yes Yes No No
Causality No No No Yes
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