Introduction to the Neurologic Examination

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    Introduction to the Neurologic Examination

    Michael F. Nolan, Ph.D.,P.T.

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    Introduction to the Neurologic Examination

    The neurological history and examination are designed to answer three

    fundamental questions regarding the structural and functional integrity of the

    nervous system:

    1) Is there evidence of an abnormality of structure or function?

    2) Where is the abnormality?

    3) What is the Nature of the abnormality?

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    1) Is there evidence of an abnormality of structure or function?

    Information needed to answer this question:

    a. An understanding of history and examination findings that fall within

    the range of normal for the patient being examined.

    What factors influence range of normal?

    b. Accurate and reliable history and examination findings from the patient

    being examined.

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    1) Is there evidence of an abnormality of structure or function? NO

    a. history and examination data accurate and reliableno neurologic

    abnormality

    b. Inaccurate history or unreliable examination datauncertain

    neurological status (false negative)

    Common causes of inaccurate history or unreliable examination data

    1. omissions

    2. technique

    3. interpretation

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    1) Is there evidence of abnormality of structure or function? YES

    a. Inaccurate history or unreliable examination datauncertain

    neurological status (false positive)

    Common causes of false positive findings on history or examination

    1. technique

    2. interpretation

    b. history and examination data accurate and reliableneurologic

    abnormality likelyproceed to questions 2 and 3

    Question 2 - Where is the abnormality?

    Question 3 - What is the nature of the abnormality

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    2) Where is the abnormality?

    Location

    Position

    Extent

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    2) Where is the abnormality Location

    Peripheral nervous system

    nerve roots (radiculopathy)

    plexus (plexopathy)peripheral nerves (neuropathy)

    neuromuscular junction

    muscle (myopathy)

    Central nervous system

    spinal cord

    side (R/L)

    brainstem

    side (R/L)

    level (medulla, pons, midbrain)

    region (paramedian, ventrolateral, dorsolateral)

    cerebellumside (R/L)

    region (vermis, hemisphere, peduncle)

    cerebrum (encephalopathy)

    side (R/L)

    lobe (frontal. parietal, occipital, temporal)

    region (cortex, subcortical white matter, deep nuclei)

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    2) Where is the abnormality Position

    Brain

    epidural

    subdural

    subarachnoid

    intraparenchymalintraventricular

    Spinal Cord

    epidural

    intrathecal (subarachnoid)intramedullary

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    2) Where is the abnormality Extent

    focal

    multifocal

    systemic/diffuse

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    3) What is the Nature of the abnormality?

    Etiology

    responsible cause or disease mechanism that results in cellular orsystemic abnormality

    Pathophysiology

    processes whereby abnormalities of cellular or systemic mechanisms

    result in abnormalities of structure and/or function

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    3) What is the nature of the abnormality Etiology

    C V V vascular/post vascular

    I I I infectious/post infectious

    N N T traumatic/post traumatic

    E D A autoimmune

    M I M metabolic/toxic

    A C I idiopathic

    A N neoplastic

    T T

    V E C congenital/hereditary

    D degenerative

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    3) What is the nature of the abnormality Pathophysiology

    Involvement primarilyof nervous system cells and tissues

    nerve cells

    nerve cell processesglial cells

    meninges

    choroid/ependymal cells

    Involvement secondaryto disease/dysfunction of other cells and organ systemsvascular/ cardiac disease

    pulmonary disease

    renal disease

    gastrointestinal disease

    endocrine disease

    immunologic disease

    orthopedic disease

    dermatologic disease

    genito-urinary disease

    hematopoietic disease

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    3) What is the nature of the abnormality Pathophysiology

    Involvement primarily of nervous system cells and tissues (expanded)

    nerve cells

    transmitter proteinsmembrane proteins

    receptor proteins

    ion channel proteins

    cytoskeletal proteins

    enzyme systems

    cytoplasmicmitochondrial

    nerve cell processes

    axons

    myelin sheath

    axonal transport systems

    glial cellsastrocytes

    oligodendrocytes

    meninges

    dura mater

    arachnoid mater

    choroid/ ependymal cells (CSF)

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    Components of the Neurological History

    Chief Complaint

    History of Present Illness

    Past Medical (Surgical) History

    Pertinent Health InformationFamily History

    Social History

    Occupational History

    Review of Systems

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    Components of the Neurological History Review of Systems

    review of systems

    skin

    head, eyes ears, nose throat (HEENT)

    breasts

    respiratory

    cardiacvascular

    gastrointestinal

    renal and urinary

    musculoskeletal

    neurologicendocrine

    psychiatric

    hematopoietic

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    Components of the Neurological Examination

    Mental Status

    Cranial Nerves

    Motor Systems (including coordination, station and gait)

    Reflexes

    Sensory Systems

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    Components of the Neurological Examination Mental Status

    Level of Consciousness

    Attention

    Orientation

    Language Function

    Learning and Memory

    Cortical and Cognitive Function

    Mood and Affect

    Thought Content

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    Components of the Neurological Examination Mental Status

    Level of Consciousness

    alert

    lethargicobtunded

    stuporous

    comatose

    Attention

    attentiveinattentive

    stablefluctuating

    Orientation

    person

    place

    time

    (situation)

    Language Function

    spontaneous speech

    fluency

    comprehension

    repetition

    naming and word findingreading and writing

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    Components of the Neurological Examination Mental Status

    Learning and Memory

    immediate recallshort term

    long term (remote)

    Cortical and Cognitive Function

    fund of knowledge

    calculation abilityproverb interpretation

    praxia

    (gnosia)

    Mood and Affect

    characterizationappropriate/ inappropriate

    Thought Content

    coherent, organized (egosyntonic)

    incoherent, disorganized (paranoia, delusions, hallucinations, phobias)

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    Components of the Neurological Examination Cranial Nerves

    Olfactory Nerve (I)

    perception (recognition, hallucinations)

    Optic Nerve (II)

    visual acuity (unaccommodated / accommodated)visual fields

    color vision

    pupils

    visual reflexes

    light reflexes (direct / indirect)accommodation reflex

    funduscopic exam

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    Components of the Neurological Examination Cranial Nerves

    Ocular Motor Nerves (III,IV,VI)

    inspectionpalpebral fissures (ptosis, proptosis)

    ocular position (strabismus, gaze shifts)

    head position (compensation)

    spontaneous movements (nystagmus)

    common complaints

    diplopia

    blurred vision

    ocular movements (monocular and binocular)

    tracking (pursuit)

    volitional

    ocular motor testing

    cover testing (heterotropia/heterophoria)

    red glass test

    corneal light reflection test

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    Components of the Neurological Examination Cranial Nerves

    Trigeminal Nerve (V)

    sensory (ophthalmic, maxillary, mandibular)

    threshold and symmetry to tactile (and thermal) stimuli

    (corneal reflex)

    motor

    masseter and temporalis strength

    reflex

    jaw jerk

    Facial Nerve (VI)

    inspection

    forehead, palpebral fissures, nasolabial fold, corner of mouth

    motor

    upper face (frontalis, orbicularis oculi)

    lower face (zygomaticus, orbicularis oris)

    enunciation

    labial soundsM

    (autonomic)

    (lacrimation)

    (sensory)

    (tasteanterior 2/3 of tongue)

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    Components of the Neurological Examination Cranial Nerves

    Vestibulocochlear Nerve (VIII)

    cochlear division

    screening testfinger rub (auditory threshold)

    deficit characterization (sensorineural vs. conduction)

    Weber

    Rinne

    vestibular divisioninspection

    nystagmus

    tests of function

    past pointing

    marching in place

    vestibulo-ocular reflexesoculocephalic reflex (dolls head maneuver)

    head thrust and head shake tests

    oculovestibular reflex (caloric testing)

    walking (oscillopsia)

    provocative tests

    Dix-Hallpike maneuver (Nylen-Barany )

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    Components of the Neurological Examination Cranial Nerves

    Glossopharyngeal (IX) and Vagus (X) Nerves

    inspection

    position of uvula and soft palate at rest

    movement of uvula and soft palate with AAHH

    (glottis - position of the vocal folds)auscultation

    hoarseness

    stridor

    enunciation

    pharyngeal soundsK(pharyngeal ((gag)) reflex)

    (observe swallowing)

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    Components of the Neurological Examination Cranial Nerves

    Spinal Accessory Nerve (XI)inspection

    atrophy, head tilt

    strength testing

    (upper) trapeziusshoulder shrug

    sternocleidomastoidhead turning

    Hypoglossal Nerve (XII)

    inspection (tongue in floor of mouth)

    atrophy/furrowing

    fasciculations

    inspection (on protrusion)

    midline/deviation

    enunciation

    lingual sounds - L

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    Components of the Neurological Examination Motor Systems

    Inspection

    Muscle Tone

    Strength

    Coordination

    Station

    Gait

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    Components of the Neurological Examination Motor Systems

    Inspection

    symmetry, bulk and contour (atrophy/hypertrophy)

    physiological/pathological

    posture (dystonic, paretic)

    adventitious (abnormal) movements

    at rest (tics, tremor, athetosis, chorea, ballismus, titubation, jerks)

    with action (paresis, ataxia, dysarthria)

    Muscle Tone

    normaldecreased (atonia, hypotonia)

    increased (spasticity, rigidity, paratonia)

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    Components of the Neurological Examination Motor Systems

    Strength

    upper limb lower limb

    shoulder abduction hip flexionelbow flexion knee extension

    elbow extension hip adduction

    wrist extension ankle dorsiflexion

    wrist flexion hip abduction

    finger extension toe extensionfinger flexion ankle plantar flexion

    finger abduction hip extension

    strength grades

    5/5 - full ROM against gravity with maximal resistance

    4/5 - full ROM against gravity with some resistance

    3/5 - full Rom against gravity only

    2/5 - full ROM gravity eliminated

    1/5 - palpable or visual evidence of contraction without movement

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    Components of the Neurological Examination Motor System

    Upper Limb Peripheral Nerve Spinal Segment

    shoulder abduction axillary C5, C6

    elbow flexion musculocutaneous C5, C6

    elbow extension radial C6, C7wrist extension radial C6, C7

    wrist flexion median C7, C8

    finger extension radial C7, C8

    finger flexion median/ulnar C8, T1

    finger abduction ulnar T1

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    Components of the Neurological Examination Motor System

    Lower Limb Peripheral Nerve Spinal Segment

    hip flexion L1, L2, L3

    knee extension femoral L2, L3, L4

    hip adduction obturator L2, L3, L4ankle dorsiflexion anterior tibial L4, L5

    hip abduction superior gluteal L4, L5, S1

    toe extension anterior tibial L4, L5

    ankle plantar flexion posterior tibial L5, S1, S2

    hip extension inferior gluteal L5, S1, S2

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    Components of the Neurological Examination Motor Systems

    Coordination

    upper limb

    finger-to-nose

    rapid alternating movements

    finger tap/alternate finger tap

    check and rebound

    lower limbheel-to-shin

    rapid alternating movements

    foot tap/alternate heel-toe tap

    StationRomberg test

    Gait

    free walking

    tandem walking

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    Components of the Neurological Examination Reflexes

    Muscle Stretch (Myotatic) Reflexes

    response characteristics evaluated

    threshold

    latency

    magnitude

    amplitude

    spread

    duration

    reflex grades

    0 - no visible or palpable muscle contraction with reinforcement

    1 - slight muscle contraction with little or no joint movement

    2 - distinct muscle contraction with slight joint movement

    3 - brisk muscle contraction with moderate joint movement

    4 - strong muscle contraction with 1-3 beats of clonus. Spread to the

    contralateral side may be noted

    (5strong muscle contraction with sustained clonus)

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    Components of the Neurological Examination Reflexes

    Muscle Stretch (Myotatic, Tendon) Reflexes

    commonly tested reflexes

    biceps brachii

    brachioradialis

    triceps brachii

    finger flexor

    quadriceps femoris

    Achilles

    abnormal muscle stretch reflexesmasseter reflex (jaw jerk)

    Hoffman

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    Components of the Neurological Examination Reflexes

    Upper Limb Peripheral Nerve Spinal Segment

    biceps brachii musculocutaneous C5, C6

    brachioradialis radial C5,C6, C7

    triceps brachii radial C6, C7, C8

    finger flexion median/ulnar C7, C8

    Lower Limb

    quadriceps femoris femoral L2, L3, L4

    Achilles posterior tibial L5, S1, S2

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    Components of the Neurological Examination Reflexes

    Cutaneous Reflexes

    plantar

    (abdominal)

    (anal sphincter)

    (cremasteric)

    (bulbocavernosus)

    Abnormal Cutaneous Reflexes

    Babinski

    palmar grasp

    persistent glabellarpalmomental

    suck, root

    snout

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    Components of the Neurological Examination Sensory Systems

    Evaluations

    symmetry

    threshold

    anesthesia, hypesthesia, hyperesthesia

    analgesia, hypalgesia, hyperalgesia, allodynia

    paresthesia, dysesthesia

    Functional Systems

    anterolateral (nociceptive) system

    lemniscal (non-nociceptive) system

    cortical sensory functions

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    Components of the Neurological Examination Sensory Systems

    Anterolateral System

    pin prick (nociceptive)

    thermal sense (thermesthesia)

    (deep pain)

    Lemniscal System

    light touch (thigmesthesia)

    tactile localization (topesthesia)2pt discrimination

    vibratory sense (pallesthesia)

    position sense (proprioception)

    movement sense (kinesthesia)

    Cortical Sensory Functions

    object identification (stereognosia)

    traced figure identification (graphesthesia)

    double simultaneous stimulation (extinction)

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    End