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1 Disclaimer § The material in this presentation has been prepared by LSK BioPartners Inc (d.b.a. LSK BioPharma/Elevar Therapeutics) and is general background information about LSK BioPartners Inc.’s activities current as at the date of this presentation. This information is given in summary form and does not purport to be complete. Information in this presentation, including forecast financial information, should not be considered as advice or a recommendation to investors or potential investors in relation to holding, purchasing or selling securities or other financial products or instruments and does not take into account your particular investment objectives, financial situation or needs. Before acting on any information you should consider the appropriateness of the information having regard to these matters, any relevant offer document and in particular, you should seek independent financial advice. § All securities and financial product or instrument transactions involve risks, which include (among others) the risk of adverse or unanticipated market, financial or political developments and, in international transactions, currency risk. This presentation may contain forward looking statements including statements regarding our intent, belief or current expectations with respect to LSK BioPartners Inc.’s businesses and operations, market conditions, results of operation and financial condition, capital adequacy, specific provisions and risk management practices. § Readers are cautioned not to place undue reliance on these forward-looking statements. LSK BioPartners Inc. does not undertake any obligation to publicly release the result of any revisions to these forward-looking statements to reflect events or circumstances after the date hereof to reflect the occurrence of unanticipated events. While due care has been used in the preparation of forecast information, actual results may vary in a materially positive or negative manner. Forecasts and hypothetical examples are subject to uncertainty and contingencies outside LSK BioPartners Inc.’s control. Past performance is not a reliable indication of future performance.

Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Page 1: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

1

Disclaimer

§ The material in this presentation has been prepared by LSK BioPartners Inc (d.b.a. LSK BioPharma/Elevar Therapeutics) and is generalbackground information about LSK BioPartners Inc.’s activities current as at the date of this presentation. This information is given insummary form and does not purport to be complete. Information in this presentation, including forecast financial information, should notbe considered as advice or a recommendation to investors or potential investors in relation to holding, purchasing or selling securities orother financial products or instruments and does not take into account your particular investment objectives, financial situation or needs.Before acting on any information you should consider the appropriateness of the information having regard to these matters, any relevantoffer document and in particular, you should seek independent financial advice.

§ All securities and financial product or instrument transactions involve risks, which include (among others) the risk of adverse orunanticipated market, financial or political developments and, in international transactions, currency risk. This presentation may containforward looking statements including statements regarding our intent, belief or current expectations with respect to LSK BioPartners Inc.’sbusinesses and operations, market conditions, results of operation and financial condition, capital adequacy, specific provisions and riskmanagement practices.

§ Readers are cautioned not to place undue reliance on these forward-looking statements. LSK BioPartners Inc. does not undertake anyobligation to publicly release the result of any revisions to these forward-looking statements to reflect events or circumstances after thedate hereof to reflect the occurrence of unanticipated events. While due care has been used in the preparation of forecast information,actual results may vary in a materially positive or negative manner. Forecasts and hypothetical examples are subject to uncertainty andcontingencies outside LSK BioPartners Inc.’s control. Past performance is not a reliable indication of future performance.

Page 2: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

LSK BioPharma Historical Highlights

2005§Company

Established as Consulting

Company

2009§Pre-Clinical

Development starts of Rivoceranib

2010§Management

Invests in Company –

Focus on Drug

Development

2012§Clinical

Development of Rivoceranib

2015§HLB acquires majority

ownership of LSK Biopharma

2017§ANGEL Study

Begins

2018§ Immunotherapy

combination trials begin

§GC 2nd line Clinical

Development begins

2018

2019§Pivotal HCC SHR-1210

Combo trial begins in collaboration with

Jiangsu Hengrui

§ANGEL Study

Completed

2019

Page 3: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

September 2019

LSKB is flying to new heights with a new name…

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Elevate ExcellenceEvolve

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Elevar Therapeutics aims to provide patients and their caregivers with exceptional choices for effective

and well-tolerated therapies.

Raising Outcomes.

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• Executive Management• Business Development• Operations• Fund Raising, M&A

Alex KimChief Executive Officer

9 years

HLB Co., LTDBoard Member

LSK BioPharmaE.V.P Board Member

MacroMed (BTG)E.V.P.

12 years9 years

1989 Theratech (Watson)1994 Samyang Corporation1996 VivoRx (Abraxis)

Page 7: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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San Francisco Office

ClinicalOperations

Biometrics Drug Safety CMC

Regulatory BusinessDevelopment

CommercialDevelopment

Salt Lake City HQ

ExecutiveManagement

Product Development

Quality Assurance

Accounting & Finance

CorporateStrategy

Seoul & Ireland -- Satellite OfficesL.A., Raleigh-Durham, Jacksonville – Remote Staff

Elevar Staffing and Offices

Page 8: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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15.53% ownership59.83% ownership

15.11% ownership9.02%(LS) 6.09%(LL)

formerly

Holding Company

Shinhwa Advance

Current Corporate Ownership

Page 9: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Pipeline

Near term corporate plan

M&A with HLB Co. LTD.HLB to acquire 100% of shares of ElevarElevar to remain as US Corporation as wholly owned sub

JV with NeoPharmaFounding a 50/50 JV in U.A.E.Commercialize Rivoceranib in Middle East / North Africa / IndiaLeveraging NeoPharma manufacturing and R&D

Partnership with HLB-LSAsia-Pacific Rivoceranib BDAsia Pacific Rivoceranib Commercialization

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Pipeline

5 Year Targets – Raising Outcomes

• Rivoceranib Approval in 5 Indications• Commercialize Rivoceranib in the US• Rivoceranib License & Distribution Deals R.O.W.• New In-House Asset in Clinical Development• In-License Asset for Pipeline

Page 11: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Rivoceranib (commonly known as Apatinib)

Selective JAK3 Inhibitor

Elevar Current Assets

Pipeline

Highly-selective oral angiogenesis inhibitor targeting solid tumorsKnown as best-in-class for activity and tolerabilityApproved & marketed in China ($350M+ annual sales)Hundreds of clinical studies in numerous indications active worldwideElevar has exclusive rights ex-China and is developing in 5 indications

Selective Inhibitor of Janus Kinase 3Potential for T-Cell Lymphoma, RA, autoimmune disorders Developed in-house at ElevarPreclinical Development in 2020Expect to file IND in early 2021

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CovanceExecutive Director, Medical & Scientific Affairs

PfizerAssociate Director, Clinical Trial Operations

2 yrs 13 years11 years

Atrix LaboratoriesDirector, Clinical Research

Dr. Steven NortonVice President

Clinical Development

• Establishing High Performance Teams• Clinical Strategy and Development• Medical and Scientific Affairs

LSK BioPharma

V.P

Present

Leading Drug Development

Page 13: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Elevar Clinical Development Team

200+ years of experience17 employees and growing20 post graduate degrees

• N=1 (MBA, PhD)• 26+ years experience

Vice President

• N=2 (2x PhD)• 10+ years experienceClinical Pharmacology

• N=5 (PhD, MD, 2x Masters) • 60+ years experience

Clinical Operations

• N=3 (PhD, Masters)• 20+ years experienceBiometrics

• N=4 (2x PhD, 2x MD, 3x Masters)• 60+ years experience

Medical &

Scientific Affairs

• N=2 (PhD, PharmD, MD)• 25+ years experience

Drug Safety & Pharmacovigilance

Page 14: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Stomach Colon Liver

Bone & Soft Tissue Head & Neck

Elevar Development

Page 15: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Stomach Cancer (GC)Treatment: ≥ 3rd Line rivoceranib monotherapy

ANGEL Study ScopeGlobal / 100 sites / 460 patients

ANGEL Study StatusReviewing full data set / preparing final report

RegulatoryDesignated orphan drug status in US, EU and Korea / pre-NDA meetingPotential NDA Filing Strategies (3rd line + w/ PFS, 4th line + w/ OS)

PIVOTAL PHASE 3 (ANGEL)

Page 16: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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ANGEL Study Important 2019 Milestones

February – Completion of Primary EndpointJune – Opening of Topline ResultsJuly through August – Internal Review of Full Data SetAugust 15 – Pre-NDA Meeting Request SentAugust 23- KSMO Abstract SubmittedAugust 30 – ESMO Abstract AcceptedSept 27 – Oct 2 – ESMO Presentation (Abstract #4088)Mid-October– Pre-NDA Meeting with US FDA

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Stomach Cancer (GC)Treatment: ≥ 2nd Line Combination – rivoceranib + paclitaxel (Taxol)

Study ScopeKorea / up to 5 sites / up to 38 patients

Study StatusEnrollment Ongoing

RegulatoryDesignated orphan drug status in US, EU and Korea

PHASE 1b/2

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Colon Cancer (CRC) Treatment: 3rd Line Combination – rivoceranib + Trifluridine/Tipiracil (LONSURF®)

Study ScopeGlobal / up to 16 sites / 100 patients

Study StatusEnrollment Starting

RegulatoryUS Investigational New Drug (IND)

LONSURF supplyTaiho

PHASE 1b/2

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Liver Cancer (HCC)

Treatment: 1st Line Combination – rivoceranib + Camrelizumab (SHR-1210)

Study ScopeGlobal / 100 sites / 510 patients

Study StatusEnrollment Started

RegulatoryUS Investigational New Drug (IND)

PartnerJiangsu Hengrui

PIVOTAL PHASE 3

Page 20: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Head and Neck Cancer (ACC)Treatment: 1st Line Monotherapy

Study ScopeUS and Korea / up to 15 sites / 55 patients

Study StatusStart-up

RegulatoryUS Investigational New Drug (IND) / Filing for orphan drug status

PIVOTAL PHASE 2

Page 21: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Bone and Soft Tissue (Sarcoma)

Treatment: Combination – rivoceranib + Nivolumab (OPDIVO®)

Study ScopeUS/ Single Site / 24 patients

Study StatusEnrolled Completed

RegulatoryUS Investigational New Drug (IND)

PHASE 1b/2

Page 22: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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FDA NDA Supporting Studies - Status

Study Type Phase 1 – Drug-Drug Interactions

Study Scope US / 2 Sites / 48 subjects

Study Status Enrollment Completed

Study Type Phase 1 – Effect of Stomach pH

Study Scope US / 2 Sites / 24 subjects

Study Status Enrollment Completed

Study Type Phase 1 – Cardiac Effects

Study Scope US / 2 Sites / 72 subjects

Study Status Enrollment Completed

Study Type Phase 1 – Effect of Liver Impairment

Study Scope US / 2 Sites / up to 28 subjects

Study Status Enrollment Ongoing

Study Type Phase 1 – Drug Metabolism

Study Scope US / Single Site / 8 subjects

Study Status Enrollment Completed

Page 23: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Rivoceranib Clinical Status

The safety and efficacy of the agents and/or uses under investigation have not been established. There is no guarantee that the agents will receive healthy authority approvaland become commercially available country for the uses being investigated.

Indication Preclinical Phase l Phase ll Phase lll ApprovalTherapy

Monotherapy3rd/4th Line Stomach

Taxane Combination 2nd Line Stomach

Lonsurf ® Combination3rd/4th Line Colorectal

Camrelizumab Combination1st Line Hepatocellular

Nivolumab Combination Bone & Soft Tissue

Monotherapy1st Line Head & Neck

Page 24: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Elevar is targeting 5 approvals in 5 years

Adenoid CysticCarcinoma

1st line

2024

Stomach Cancer

2nd line

2024

Liver Cancer

1st line

2023

Colorectal Cancer

3rd line

2023

The safety and efficacy of the agents and/or uses under investigation have not been established. There is no guarantee that the agents will receive healthy authority approvaland become commercially available country for the uses being investigated.

Stomach Cancer

Late Stage Monotherapy

2020/21

Page 25: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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4 years

DendreonExecutive Director, Urology & Oncology

AbbVieHead of Sales, Oncology

Abbott LaboratoriesSenior Executive, Market Access

6 years12 years

Kate McKinleyVice President

Commercial and BusinessDevelopment

1998 Abbott Laboratories

• Product Launch & Commercialization• Sales & Marketing Leadership• Market Access & Training

Present

LSK BioPharmaV.P

Global Patient Access to Rivoceranib

Page 26: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Plans for Launching Rivoceranib

Commercialization

License / Distribution

Page 27: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Rivoceranib US Commercial Plan

Phase 3 Completion Pre-NDA NDA Filing Post-NDA Approval Launch

Commercial Plan & Organizational

Structure

HCP & Payer Research

Establish Working Groups & SOPs

Strategic Partnerships

Value Proposition / Scientific Platform

Conventions

Data Platform: Patient Journey

Brand Strategy

Account Targeting, Alignment, Sizing

Hiring

Training: DSA, Product, Leadership, Selling

Skills

HUB & Dossier

Resource Development & Ad Boards

Hiring

Hiring

Execute Launch Training

Pre-Approval Meetings

Execution

Measurement & Evaluation

Page 28: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Rivoceranib peak annual sales potential ($MM)

The safety and efficacy of the agents and/or uses under investigation have not been established. There is no guarantee that the agents will receive healthy authority approvaland become commercially available country for the uses being investigated.

$900

$250$850

$150

$650

GC 2nd Line GC 4th Line HCC 1st Line ACC 1st Line CRC 3rd Line

Stomach Cancer (GC)

2nd Line

Stomach Cancer (GC)

Late Stage Monotherapy

Liver Cancer (HCC)

Colon Cancer (CRC)

Adenoid Cystic Carcinoma (ACC)

1st Line

3rd Line

1st Line

Page 29: Investor Deck Draft FINAL - KIRSw3.kirs.or.kr/download/announce/HLB IR Book_2019.09.pdf2015 HLB acquires majority ownership of LSK Biopharma 2017 ANGEL Study Begins 2018 Immunotherapy

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Raising Outcomes.

Targeting 5 approvals in 5 years

Large peak sales potential

In-house Drug Discovery Program

Co-development trials with large partners

200+ Combined Years of Clinical Experience

Experienced Leadership Team

01 02

03 04

05 06

Elevar Therapeutics

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2825 E Cottonwood Pkwy Suite 180,Salt Lake City, UT 84121 U.S.A.Phone: +1 801-303-7440Fax: +1 801-303-7455

3 September 2019