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Jonathan B. Bricker, PhD Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Fred Hutchinson Cancer Research Center Center University of Washington University of Washington Telephone-Delivered ACT for Telephone-Delivered ACT for Adult Smoking Cessation: A Adult Smoking Cessation: A Feasibility Study Feasibility Study

Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

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Page 1: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Jonathan B. Bricker, PhDJonathan B. Bricker, PhDFred Hutchinson Cancer Research CenterFred Hutchinson Cancer Research Center

University of WashingtonUniversity of Washington

Telephone-Delivered ACT for Telephone-Delivered ACT for Adult Smoking Cessation: A Adult Smoking Cessation: A

Feasibility StudyFeasibility Study

Page 2: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Smoking is a Deadly Worldwide Smoking is a Deadly Worldwide BehaviorBehavior

21% of US adults smoke (CDC, 2006).

1.2 billion smokers worldwide (Mackay, 2006).

Kills 5 million per year now and 10 million per year by 2025 worldwide (Hatsumaki et al., 2008).

Page 3: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Smoking Leads to Loss of Valued Smoking Leads to Loss of Valued LivingLiving

Medical illnesses: multiple cancers, heart disease, stroke, COPD (CDC, 2006).

Work: absenteeism and discrimination (Bunn et al., 2006).

Stigma & Shame (Stuber et al., 2008).

Page 4: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Quitlines Address This Problem Quitlines Address This Problem

1-800-QUIT-NOW1-800-QUIT-NOW

Page 5: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Quitlines: Addressing Barriers to Quitlines: Addressing Barriers to ReachReach

Accessible: In US, 95% have a telephone, 85% have cell phones. (Pew Internet & American Life Project, 2009)

Available: All 50 States have a quitline as do most of Europe and Latin America

Cost-effective: Covered by insurance, Medicaid, or the state. Costs (about $350) less than face-to-face and with only 17% lower fraction of effectiveness.

Relatively brief: about 90 minutes total (3 to 9 sessions)

Many demographics make use: Men, minorities, poor

Page 6: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

ProblemProblem:: Quitlines have limited Quitlines have limited effectivenesseffectiveness

§ 12-14% quit rates at 12 month post randomization (Stead et al., 2006).

§ We are not helping 86-88% of smokers to quit!

Page 7: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Why don’t they work well?Why don’t they work well?

A lack of attention to basic processes that lead people to smoke and to relapse!

Page 8: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Basic Processes: Avoidance & Basic Processes: Avoidance & Lack of CommitmentLack of Commitment

Avoidance Coping at age 18 predicted a 2.75 times higher odds (p <.001) of smoking two years later (99% data retention; N = 3305; Schiff, Bricker, et al., in review)

Lack of Commitment to Quitting predicted a 2.32 times higher odds (p <.01) of relapse 26 weeks after quit date (92% data retention; N = 157; Kahler et al., 2006)

Page 9: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Acceptance & Commitment Acceptance & Commitment Therapy Directly Targets These Therapy Directly Targets These

Basic ProcessesBasic Processes

Page 10: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Acceptance Acceptance of your of your

“baggage”“baggage”

Committed Committed Action in Action in valued valued

direction direction

Page 11: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Promise of ACT for Smoking Promise of ACT for Smoking CessationCessation

1. ACT vs. NRT: N= 76; 21% vs. 9% biochemically verified 24-hour abstinence at 12-month follow-up (n.s. in ITT; Gifford et al., 2004)

2. ACT + FAP vs. Zyban: N = 302; 35% vs. 20% 30-day abstinence at 12-month follow-up (p <.05 in ITT; Gifford, Kohlenberg et al., in review)

Page 12: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Promise of ACT for Smoking Promise of ACT for Smoking CessationCessation

3. En Español: ACT vs. CBT: N = 81; 30% vs. 13% 30-day abstinence at 12-month follow-up (p <.05 in ITT; Hernandez-Lopez, Luciano, Bricker et al., 2009; Psychology of Addictive Behaviors)

Page 13: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Telephone Study AimsTelephone Study Aims

1. Determine adherence to ACT telephone protocol.

2. Determine participant receptivity to ACT intervention.

3. Examine change in ACT processes of (a) acceptance and (b) commitment.

4. Determine post treatment and 12-months post treatment abstinence rates.

Page 14: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Sample (N = 14)Sample (N = 14)1. Female: 40%

2. Minority: 53% (primarily African American)

3. Median age: 49

4. Low income: 64%

5. Depressed (MDE screen): 40%

6. Over half a pack per day: 64%

Page 15: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

ProcedureProcedure1. Developed ACT telephone protocol (5-session; 90

minute total).

2. Recruited primarily from high-minority population of Dallas TX metro area.

3. Primary Eligibility: Adult daily smoker wishing to quit within the next 30 days.

Page 16: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Fidelity RatingsFidelity Ratings1. Intra- and inter-rater reliabilities: all Kappas = 1 (perfect agreement).

2. Overall Adherence & Overall Competence: 4.61 (SD: .63) & 4.81 (SD: .39) mean ratings (out of 1 to 5 rating).

3. Acceptance & Committed Action: 4.87 (SD: .35) & 4.83 (SD: .50) mean ratings.

4. Percent of calls meeting or exceeding benchmark rating of “4” or more ranged from 93% to 100%.

Schimmel-Bristow, Bricker et al. (2010; Society of Behavioral Medicine)

Page 17: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

First evidence First evidence that ACT Can Be Briefly that ACT Can Be Briefly Delivered ViaDelivered Via Telephone Telephone

1. Mean length of contact time: 82 minutes

2. Mean number of counseling calls: 3.5 (33% had all five calls)

Page 18: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Participants Were Highly ReceptiveParticipants Were Highly Receptive

1. Felt respect by counselor: 100%

2. Intervention was a good fit: 86%

3. Intervention helped them quit: 86%

Page 19: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

ACT Processes Changed ACT Processes Changed

1. Acceptance of physical cravings (p = .001), emotions (p = .048), and thoughts (p = .085) that cue smoking increased from baseline to end of treatment.

2. Commitment to quitting increased from baseline to end of treatment (p = . 01).

Page 20: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Telephone-Based ACT: Cessation Telephone-Based ACT: Cessation Results at Results at 20 Days20 Days Post Treatment Post Treatment

(93% retention)(93% retention)

1. 24-hour point prevalence: 43%

2. 7-day point prevalence: 29%

3. Harm reduction, from daily to less than daily smoking: 62%

Page 21: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Cessation Results at Cessation Results at 12-months12-months Post Post Treatment (93% retention)Treatment (93% retention)

1. 12-month prolonged quit: 29% (ITT) & 31% (with complete data)

2. No relapsing among any study participants

Bricker et al. (2010); Nicotine & Tobacco Research, 12, 454-458.

Page 22: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

The Promise of Cessation/Process The Promise of Cessation/Process Results Results

1. Over double the 12% quit rate of adult quitline counseling (Stead et al., 2006)

2. Similar to all prior face-to-face ACT quit studies (30%-35%)

Page 23: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Future PlansFuture Plans1. Obtain funding to test effectiveness of telephone-

delivered ACT vs. CBT for smoking cessation.

2. Adapt & test protocol for other outcomes: alcohol & substance use, weight loss/stigma.

3. Once effectiveness data are available, disseminate telephone protocol, provide training to all interested clinicians, and implement in quitlines.

Page 24: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility
Page 25: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Fidelity MethodsFidelity Methods1. Adapted Hayes & Gifford ACT fidelity measure for the

telephone protocol.

2. 100% of the 54 counseling sessions coded by trained rater.

3. 20% random sample re-rated for intra-rater reliability.

4. 20% random sample rated by a second independent rater for inter-rater reliability.

Page 26: Jonathan B. Bricker, PhD Fred Hutchinson Cancer Research Center University of Washington Telephone-Delivered ACT for Adult Smoking Cessation: A Feasibility

Contact Info

Jonathan Bricker, PhD

Email: [email protected]