9. Codivilla A. On the means of lengthening, in the lower limbs, the muscles and tissues which are shortened through deformity. J Bone Joint Surg Am. 1905;s22:353–369. 10. Ilizarov GA. The tension-stress effect on the genesis and growth of tissues: part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res. 1989;(238):249 –281. 11. Ilizarov GA. The tension-stress effect on the genesis and growth of tissues: part II. The influence of the rate and frequency of distraction. Clin Orthop Relat Res. 1989;(239):263–285. 12. Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997;38(6):563–576. 13. Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacu- um-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997;38(6): 553–562. 14. Moues CM, Heule F, Hovius SE. A review of topical negative pressure therapy in wound healing: sufficient evidence? Am J Surg. 2011;201(4):544 –556. 15. Orgill DP, Manders EK, Sumpio BE, et al. The mechanisms of action of vacuum assisted closure: more to learn. Surgery. 2009; 146(1):40 –51. 16. Labler L, Rancan M, Mica L, Harter L, Mihic-Probst D, Keel M. Vacuum-assisted closure therapy increases local interleukin-8 and vascular endothelial growth factor levels in traumatic wounds. J Trauma. 2009;66(3):749 –757. 17. Scherer SS, Pietramaggiori G, Mathews JC, Prsa MJ, Huang S, Orgill DP. The mechanism of action of the vacuum-assisted closure device. Plast Reconstr Surg. 2008;122(3):786 –797. 18. Gregor S, Maegele M, Sauerland S, Krahn JF, Peinemann F, Lange S. Negative pressure wound therapy; a vacuum of evidence? Arch Surg. 2008;143(2):189 –196. JOURNAL CME QUESTIONS Negative-Pressure Wound Therapy Which of the following is a contraindication for negative-pressure wound therapy? a. Traumatic wounds associated with open fractures b. Fasciotomy wounds c. Wounds with exposed vessels and nerves d. Wounds associated with exposed tendons, bones, and joints e. Wounds with exposed hardware The most appropriate approach for negative- pressure wound therapy includes which of the following? a. The dressing changes should be at intervals of 7 to 11 days b. The duration of therapy is anywhere from a few days to several months c. The size and severity of the wound should not dictate the length of treatment d. It should not be used in conjunction with antibi- otics e. In the event of a suction leak, the treatment should be abandoned because reinforcement of the adhesive is not recommended To take the online test and receive CME credit, go to http://www.jhandsurg.org/CME/home. 1832 NEGATIVE-PRESSURE WOUND THERAPY In Brief JHS Vol A, September

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1832 NEGATIVE-PRESSURE WOUND THERAPY

InBrief

9. Codivilla A. On the means of lengthening, in the lower limbs, themuscles and tissues which are shortened through deformity. J BoneJoint Surg Am. 1905;s22:353–369.

10. Ilizarov GA. The tension-stress effect on the genesis and growth oftissues: part I. The influence of stability of fixation and soft-tissuepreservation. Clin Orthop Relat Res. 1989;(238):249–281.

11. Ilizarov GA. The tension-stress effect on the genesis and growth oftissues: part II. The influence of the rate and frequency of distraction.Clin Orthop Relat Res. 1989;(239):263–285.

12. Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new methodfor wound control and treatment: clinical experience. Ann PlastSurg. 1997;38(6):563–576.

13. Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacu-um-assisted closure: a new method for wound control and treatment:animal studies and basic foundation. Ann Plast Surg. 1997;38(6):

JOURNAL CME QUESTIONS

JHS �Vol A, Se

14. Moues CM, Heule F, Hovius SE. A review of topical negativepressure therapy in wound healing: sufficient evidence? Am J Surg.2011;201(4):544–556.

15. Orgill DP, Manders EK, Sumpio BE, et al. The mechanisms ofaction of vacuum assisted closure: more to learn. Surgery. 2009;146(1):40–51.

16. Labler L, Rancan M, Mica L, Harter L, Mihic-Probst D, Keel M.Vacuum-assisted closure therapy increases local interleukin-8 andvascular endothelial growth factor levels in traumatic wounds.J Trauma. 2009;66(3):749–757.

17. Scherer SS, Pietramaggiori G, Mathews JC, Prsa MJ, Huang S,Orgill DP. The mechanism of action of the vacuum-assisted closuredevice. Plast Reconstr Surg. 2008;122(3):786–797.

18. Gregor S, Maegele M, Sauerland S, Krahn JF, Peinemann F, LangeS. Negative pressure wound therapy; a vacuum of evidence? Arch

553–562. Surg. 2008;143(2):189–196.

Negative-Pressure Wound Therapy

Which of the following is a contraindication fornegative-pressure wound therapy?

a. Traumatic wounds associated with open fractures

b. Fasciotomy wounds

c. Wounds with exposed vessels and nerves

d. Wounds associated with exposed tendons, bones,and joints

e. Wounds with exposed hardware

The most appropriate approach for negative-pressure wound therapy includes which of thefollowing?

a. The dressing changes should be at intervals of 7 to11 days

b. The duration of therapy is anywhere from a fewdays to several months