the

Record U. S. DEPARTMENT OF

HEALTH, EDUCATION, AND WELFARE

NIA Scientific Director Dr. Richard C. Greulich Is Dr. Shock's Successor

Dr. Greulich joined NIDR in 1966 and moved to NIA in 1974.

Dr. Richard C. Greulich has been appointed scientific director of the National Institute on Aging.

He succeeds Dr. Nathan Shock who retired recently. Dr. Shock will continue his research on aging as an NIA scientist emeritus.

As scientific director Dr. Greu-lich is in charge of the NIA Intra-mural Research Program located at the Gerontology Research Center in Baltimore, Md.

Held Other NIA Posts Dr. Greulich previously had been

acting director of NIA and special assistant to the NIA Director. He joined NIH in 1966 as director of Intramural Research for the Na-tional Institute of Dental Research, a position he held until 1974.

Dr. Greulieh earned his B.A. in biology from Stanford University in 1949 and his Ph.D. in anatomy from McGill University in 1953.

Taught at UCLA He then taught at the University

of California, Los Angeles, where he was professor of anatomy in the School of Medicine, and professor of oral biology and chairman of the Division of Oral Biology in the School of Dentistry.

The recipient of various honors, (See DR. GREULICH, Page 2)

June 28,1977 Vol. XXIX, No. 14

NIH Honors and PHS Medals Presented Yesterday During Ceremony Held in CC

At the Ninth Annual NIH Honor Awards Ceremony on Monday, June 27, various staff members were recognized for their outstanding accom-plishments. The NIH Director's Award was presented to 35 Civil Service employees and 1 former NIH employee, and the PHS Commendation Medal was presented to 26 Commissioned Officers.

The NIH EEO Award of the Year, the Harvey J. Bullock, Jr., Award for Equal Opportunity Achievements, and Forty Year Length-of-Service Awards were also presented.

In addition, NIH Director Dr. Donald S. Fredrickson, and NIMH Director Dr. Bertram S. Brown, recognized an NIMH Visiting Fellow for his heroic art performed in a laboratory in the Clinical Center.

Dr. Fredrickson presented the awards, and Dr. Thomas E. Malone, NIH Deputy Director, served as master of ceremonies and read the award citations.

Dr. Stuart M. Sessoms, Senior Vice President of Blue Cross-Blue Shield of North Carolina, delivered the keynote address. A former NIH staff member, Dr. Sessoms held various positions, including that of NIH Deputy Director, during the period of 14 years he was at NIH.

Recipients of the NIH Director's Award are: OFFICE OF THE DIRECTOR

WILLIAM T. CARRIGAN III, chief, Special Projects Branch, Office of Program Planning and Evaluation, "For invaluable assistance to Directors of NIH over a 20-year period through use of writing, editorial, and presentation skills to illuminate NIH policy perspectives."

BELIA L. CEJA, special assistant to the Director, NIH, Immediate Office of the Director, "For virtuosity in maintaining the smooth and efficient operation of the Immediate Office of the Director, a role she per-forms with exceptional diligence, tact, and good judgment."

ANABEL L. HOLLIDAY, assistant director for Policy, Division of Personnel Management, Office of Administration, "For sensitive and creative development of personnel policy and for the establishment of a system of personnel program evaluation."

NATIONAL LIBRARY OF MEDICINE DR. ERNEST M. ALLEN, associate director, Extramural Programs,

(See Honors and Awards Ceremony, Pages 5-7)

Ms. Ceja Ms. Holliday Dr. Allen

x .

Mr. Goldstein Ms. Koiuma Ms. Golumbic Dr. Schlom

NATIONAL INSTITUTES OF HEALTH

Dr. Vida Beaven Named New Special Assistant To NIH Deputy Director

Dr. Beaven assumed her new post in May of this year after serving in a variety of positions in both NIH and in the office of the Assistant Secre-tary of Health, HEW.

Dr. Vida H. Beaven has been ap-pointed Special Assistant to NIH Deputy Director Dr. Thomas E. Malone.

In her new position she will per-form special NIH-wide projects as assigned by the Deputy Director and prepare analyses of research, scientific issues, and problems ad-dressed by the Office of the Direc-tor, NIH. In addition she will ensure that activities are carried out according to agency policy and objectives.

Dr. Beaven brings to her new assignment both scientific and man-agerial background.

Studied in London She received her A.B. and A.M.

degrees from Indiana University. She then studied for a year at the University of London, and received her Ph.D. degree in biochemistry from George Washington Univer-sity in 1968. Her predoctoral re-search was conducted in the Na-tional Heart, Lung, and Blood Institute intramural program.

Dr. Beaven then held a 3-year staff fellowship in NHLBI and con-ducted research in biochemical pharmacology, and continued her

(See DR. BEAVEN, Page4)

Page 2 June 28,1977 THE NIH RECORD

Record Published biweekly at Bethesda, Md., by the Editorial Operations Branch, Division of Public Information, for the information of employees of the National Institutes of Health, Department of Health, Education, and Welfare, and circulated by request to interested writers and to investi-gators in the field of biomedical and related research. The content is reprintable without permission. Pictures are available on request. The NIH Record reserves the right to make corrections, changes, or dele-tions in submitted copy in conformity with the policies of the paper and the Department of Health, Education, and Welfare.

NIH Record Office Bldg. 31 , Rm. 2B-03. Phone 49-62125

Editor Frances W. Davis

Associate Editor Fay Leviero

Associate Editor Heather Banks

Staff Correspondents ADA, Judy Fouche; CC, Susan Gerhold; DCRT, Frances Sarles; DRG, Sue Meadows; DRR, Jerry Gordon; DRS, Arthur F. Moore; FIC; George Presson; NCI, Dr. Robert M. Hadsell; NEI, Julian Morris; NHLBI, Bill Sanders; NIA, Ann Shalowitz; NIAID, Jeanne Winnick; NIAMDD, Pat Sheridan; NICHD, Tina Mclntosh; NIDR, Sue Hannon; NIEHS, Elizabeth Y. James; NIGMS, Wanda Warddell; NIMH, Betty Zubovic; NINCDS, Carolyn Holstein; NLM, Roger L. Gilkeson.

'The Cutting Edge1 Is NIDR Interdisciplinary Workshop Proceeding

The publication of the proceed-ings of a recent symposium/work-shop on the interfacial dynamics of cutting and grinding has been announced by the National Insti-tute of Dental Research.

Entitled The Cutting Edge, the collected essays and discussions present readers in the scientific, engineering, and dental communi-ties with an authoritative reference document of the state-of-the-art of cutting dynamics.

Many studies of the cutting and grinding of teeth have been re-ported in the past, but virtually all of them have dealt empirically with specific situations related to the development of new instru-ments, to the reduction of wear and prolongation of instrument life,

DR. GREULICH (Continued from Page 1)

awards and fellowships, in 1963 Dr. Greulich was the inaugural awardee of the International Asso-ciation for Dental Research Award for Basic Research in Oral Science. In 1971 he received a DHEW Su-perior Service Award. From 1962 to 1963, Dr. Greulich was an NIH Special Research Fellow.

or to improving the efficiency of instruments employed in industry.

The Cutting Edge provides a cur-rent text and a review of recent research from a wide variety of viewpoints.

The processes of cutting and the theories involved are interdiscipli-nary, and contributors to this symposium include experts in den-tistry, polymers, crystals, ultra-sound, and solvents, as well as mining and industrial engineers.

A special group award was recently presented to Media Unit employees of the

HOLE-IN-ONE-GANG—Three members of the NIH Golf Association who have scored holes-in-one during the golf league's 12-year history attempt to convey what club each player used. Ken Jones of NCI (r) used a four iron on the 12th hole at Brooke Manor June 3rd; Russ Ulshafer of DRG (c) used a wedge on the second hole at Bretton Woods last August, and Marshall DePue of DCG (I) used a five iron on the 14th hole at Bretton Woods in 1973. By coincidence, all were members of the Westwood team at the time. A fourth member. Bill Dixon of NCI, now retired, scored his ace at the Washing-tonian National course in 1972.

K-6 Vacancies Available At Ayrlawn Elementary

A few vacancies remain in the K-6 programs at the Ayrlawn Ele-mentary School near NIH.

The before and after school pro-gram, operated by Parents of Pre-schoolers, Inc., runs Mondays through Fridays and on all school holidays which are not legal holi-days observed by NIH. Sessions are from 7:30 a.m. to 6 p.m. except for the hours when children attend public school classes.

Both kindergarten and grades 1-6 meet at the Ayrlawn School. A full day summer program is also operated for kindergarten aged children.

Interested parents should call Virginia Burke at 496-1811 or Sandra Brooks at 530-5550.

Single copies of this publication are available. Contact: Dr. Thomas M. Valega, Room 510, Westwood Bldg., (301-496-7492).

ceeding production requirements in FY 1976: (I to r) George Gardner, chief. Media and Glassware Section, ESB; John Green, Michael Kirkley, Mary Penn, Anita Biser, Gerald Taylor, Emma Suggs, Frances Gallegos, James Young, Anna Hall, Essie Olds, Charles Magruder, Charlette Chun, Catherine Johnson, Morris Damuth, Dorothy Jones, and Robert Grubbs, assistant chief of the Section. Other awardees, not present for the photograph, were: Delores Delauder, Regina Young, Carrie Attaway, Martin Blum, Frank King, Jody Wiley, Jamimo Nestor, and Louis Righter.

Bioregulation of Vectors Topic of NIAID Report

The National Institute of Allergy and Infectious Diseases has pub-lished a conference report entitled Biological Regulations of Vectors.

The conference was held to pro-vide a forum to report fundamental research leading to more effective methods of bioregulation of insects and other invertebrates that trans-mit disease agents. The conference also focused on coordination of NIAID-supported bioregulation in-vestigations with those of other agencies and institutions.

Use of microorganisms to con-trol disease vectors is recognized as an important approach to pre-venting certain tropical diseases. It has become particularly pertinent as chemical methods of pest control have become ecologically unsuitable.

Bioregulation of vectors refers to the manipulation of living agents in a habitat in order to re-duce the number of specific disease-transmitting organisms.

Conference participants ad-dressed problems of detecting, iso-lating and identifying bacteria and fungi for use as agents in biocon-trol. Nutrition, growth conditions and mode of action of vectors were emphasized. The conference also focused on those agents which use fermentation as a means of mass propagation.

Copies of the conference report are available for $2.50 through the Superintendent of Documents at the U.S. Government Printing Office, Washington, D.C. 20402. Re-quest Stock Number 017-044-00028-1.

Whenever ideas fail, men invent words.—Martin H. Fischer.

Division of Research Services for ex-

THE NIH RECORD June 28,1977 Page 3

WHERE'S THE FIRE?—The NIH Fire Department and Emergency Prepared-ness Office this month conducted fire drills for Bldg. 31—the first drills in the history of the office building. Separate drills were held for the A, B, and C wings. Evacuation of the A wing—the most populous, with more than 1,000 em-ployees—took 9 minutes, 35 seconds, while B wing, with about 500 employees, was completed in 5 minutes, 32 seconds. Evacuation time for the C wing, with

Women's Golf Tees Off; Team Captains Elected The NIH R&W Women's Golf A small group participating in

Association has had a number of the Spring Golf Weekend at the activities during the early weeks Tides Lodge, Irvington, Va. en-of the 1977 season. Twenty-four joyed beautiful weather May 13-15. members played in the Betty The next area outing was June 20 Sanders Memorial Open on April at Brooke Manor Country Club, 13. 16300 Georgia Ave., Rockville.

Bibi Furberg and Sue Hamilton Ties Result won the trophies for low gross and

low net scores; Linda Weir and During May, 36 weekday nine-Roberta Seward won the special hole matches were played. A Flight prizes. The evening business-social teams appear particularly evenly meeting on April 21 was well at- matched—5 of their 11 matches re-tended. sulted in ties!

NIH women who are interested Elect Captains in golf and the Association may

The team captains are elected dur- call Sue Hamilton (scorer), Roberta ing that meeting are: Peggy Powell Seward (treasurer), or Mary Sears and Bibi Furberg for A Flight, (secretary) for information. Connie Percy and Rose Shreiber for B Flight, and Bertha LeCompte and Rita Dettmers for C Flight. Grants Assoc. Seminar

Nominations Due July 29 July 29 is the deadline for B/I/D

Directors' nominations for the 1977-78 Grants Associates Seminar Series.

Beginning in September, these weekly seminars will cover a va-riety of topics related to extramural research. Those interested should forward their curricula vitae through their immediate super-visors to their respective B/I/D Directors.

Forward Nominations Dr. Ronald W. Estabrook, Virginia Lazenby O'Hara professor and chair- Directors are asked to select for man of the department of biochem- nomination no more than two can-istry. University of Texas Health Sci- didates by forwarding those per-ence Center at Dallas—and a grantee sons' CV's with a memo of endorse-of the NIGMS Pharmacology-Toxi- ment to A. Robert Polcari, execu-cology Program—has received the tive secretary, Grants Associates FASEB Award for Research in the Life Program, Westwood Bldg., Room Sciences, for his contributions to the 2A-03. "understanding of cytochrome P-450- The NIH Associate Director for mediated electron transport reactions Extramural Research and Training required for the metabolism of ster- will make the final selection of oids, carcinogens and drugs." seminar participants.

about 500 people, was not available at press time. Fire Department and Emergency Preparedness personnel said these first drills were successful but that they are planning more drills to further reduce the evacuation times. Floor, elevator, and stairwell marshals assisted in the drill, which was planned by Emergency Preparedness Officer Arthur McKay, Bldg. 31 Warden Paul Wade, and Deputy Warden Carroll Butts.

James Kellum Is Retiring After 35 Years at NIH '

Mr. Kellum was named chief of the NSS in 1965, directing night house-keeping employees in the CC.

James Kellum, chief of the Night Service Section, Clinical Center Environmental Sanitation Control Department, retires today after 35 years at NIH.

Mr. Kellum began his NIH ca-reer in December 1940, assigned to the Building Management Branch. In 1943 he was called to serve with the SeaBees but returned to NIH in 1945 after his discharge.

Present for the groundbreaking ceremonies of the CC, in March 1953 Mr. Kellum transferred to the Night Service Section, ESCD.

Mr. Kellum's retirement plans in-clude working within his commu-nity and remaining active in his church.

Providence requires three things of us before it will help us—a stout heart, a strong arm, and a stiff upper lip.—Sam Slick.

NIH Sailing Association Plans Picnic for July 17

The NIH Sailing Association picnic will be held Sunday, July 17, at noon at Thomas Point Park—a beautiful wooded area, three miles south of Annapolis. Facilities in-clude tables, grills, and a rain shel-ter. The Sailing Association will provide beverages.

Anyone interested in sailing or having a good time is invited to come. The NIH boats will be avail-able for sailing throughout the afternoon. Anyone who owns a boat —small or large—is encouraged to trailer or sail it to the picnic. Charter Boats

Association members can take advantage of a free charter in sailing an NIH boat from Back Creek to Thomas Point in the morning or in returning a boat to Back Creek in the evening.

A sign-up sheet for the free charters is at the R&W Activities desk in Bldg. 31. Directions on get-ting to the picnic are also available there.

If the picnic is cancelled because of rain, an alternate date will be arranged in August or September. For further details call Joan Beer-weiler, Ext. 66244.

Dr. Perry Speaks July 7 On Knowledge Transfer

Dr. Seymour Perry, Special Assistant to the NIH Director, will speak on Knowledge Trans-fer from Biomedical Research to the Health Care Delivery System at a seminar on Thurs-day, July 7, from 3 to 5 p.m., Bldg. 31, Conference Room 6.

The seminar is sponsored by the Committee on Science and Human Values. Everyone is welcome.

Page 4 June 28,1977 THE NIH RECORD

NIH Visiting Scientists Program Participants

6/1—Dr. Daniel Glinoer, Bel-gium, Clinical Endocrinology Branch. Sponsor: Dr. Jacob Rob-bins, NIAMDD, Bg. 10, Rm. 8N315.

6/1—Dr. Shu-ling Caroline Hu, Taiwan, Carcinogenesis Branch. Sponsor: Dr. Beatrice Chen, NCI, Bg. 37, Rm. 2C16.

6/1—Dr. Gary Murray, Canada, Laboratory of Neurochemistry. Sponsor: Dr. David Neville, NIMH, Bg. 36, Rm. 3D30.

6/1—Dr. Susanna Schlegel-Haue-ter, Switzerland, Laboratory of Bi-omedical Sciences. Sponsor: Dr. J. C. Robinson, NICHD, Bg. 6, Rm. 408.

6/3—Dr. Matthijs Lopes-Cor-dozo, The Netherlands, Laboratory of Neurochemistry. Sponsor: Dr. R. W. Albers, NINCDS, Bg. 10, Rm. 3D04.

Visits NCI 6/5—Dr. Benoit deCrombrugghe,

Laboratory of Molecular Biology. Sponsor: Dr. Ira Pastan, NCI, Bg. 37, Rm. 4B27.

6/5—Dr. George Ross, U.S.A., Laboratory of Brain Evolution and Behavior. Sponsor: Dr. John B. Calhoun, NIMH, Bg. 112, Pooles-ville, Md.

6/5—Dr. Tsutomu Takeuchi, Ja-pan, Laboratory of Parasitic Dis-eases. Sponsor: Dr. Eugene Wein-bach, NIAID, Bg. 5, Rm. 124.

6/5—Dr. Oren Zinder, Israel, Reproduction Research Branch. Sponsor: Dr. Kevin Catt, NICHD, Bg. 10, Rm. 13N246.

6/7—Dr. Edouard M. Cantin, United Kingdom, Laboratory of Oral Medicine. Sponsor: Dr. Abner Notkins, NIDR, Bg. 30, Rm. 121.

• 6/7—Dr. Claude Irene Palmer, United Kingdom, Laboratory of Neural Control. Sponsor: Dr. Ed-ward Schmidt, NINCDS, Bg. 36, Rm. 5A23.

6/7—Dr. Alain Van Dorsselaer, Prance, Laboratory of Chemistry.

Cleveland Clinic Finds Lead Accumulates In Smoking Mothers and Their Fetuses

Cigarette smoking during pregnancy causes lead to accumulate in the fetuses of smoking mothers as well as in the mothers themselves, accord-ing to researchers working at the NIH-supported Perinatal Clinical Research Center at Cleveland Metropolitan General Hospital.

The Cleveland research indicates for the first time a direct correla-tion between increased lead in smoking mothers and lead found in their infants, according to Dr. Mortimer Rosen, principal investi-gator at the center.

The Perinatal Clinical Research Center, supported by the Division of Research Resources, is a minia-ture research hospital within the larger Cleveland Metropolitan Gen-eral Hospital, providing highly specialized clinical research facili-ties to the entire medical staff of the institution.

Lead Accumulation Studied According to Dr. Rosen, the re-

search performed by Drs. Paul and Betty Kuhnert, members of the center investigative team, origi-nally looked at the problem of lead accumulation in pregnant women who lived in industrialized urban areas.

This study found that the lead accumulation in both the mothers and fetuses was high enough to cause inhibition of the enzyme aminolevulinic acid dehydratase (ALAD), an enzyme which helps Sponsor: Dr. Wolfgang Burger-meister, NIAMDD, Bg. 4, Rm. 235.

6/8—Dr. Hua-Puan Lam, Ma-laysia, Environmental Biology and Chemistry Branch. Sponsor: Dr. E. W. Van Stee, NIEHS, Research Triangle Park, N.C.

6/13—Dr. Venkat Ramaiah Muk-ku, India, Laboratory of Molecular Biology. Sponsor: Dr. George John-son, NCI, Bg. 37, Rm. 2E26.

6/15—Dr. Vincent Zigas, Aus-tralia, Laboratory on Central Nerv-ous System Studies. Sponsor: Dr. D. Carleton Gajdusek, NINCDS, Bg. 36, Rm. 5B25.

At a recent meeting of the National Library of Medicine Board of Regents, chairman Dr. Joseph F. Volker (r) presented Emilie Wiggins (second from r ) , head of NLM's Cataloging Section, with the 1977 Regents Award, citing her efforts to make the NLM catalog file conform fully to the current Anglo-American rules and her massive restructuring and modernization of the NLM Classification. NLM Director Dr. Martin M. Cummings presented the 1977 NLM Directors Award to three employees who participated in the May 1976 Colloquium on the Bicentennial of Medicine in the U.S.: Mary Corning, Dr. John Blake (c), and Dr. Peter Olch (not in photo).

Smoking during pregnancy can result in the accumulation of lead in both the mother and her fetus, according to a recent study conducted in the Perinatal Clinical Research Center at Cleveland Metropolitan General Hos-pital. The special research unit is one of 83 such centers funded by DRR.

red blood cells make hemoglobin. The investigators then looked

specifically at those mothers who smoked and found that cigarette smoking can cause additional lead accumulation in both the mothers and their infants.

Infant Lead Levels Increase Drs. Kuhnert report that the in-

fants' blood lead levels were always less than the mothers' levels, but that the lead in the infants in-creased in direct proportion to the levels found in the smoking mothers.

The investigators determined the blood lead levels of the mothers and their infants and correlated them with the inhibition of the enzyme ALAD.

ALAD is extremely sensitive to lead and therefore usually is af-fected by lead long before other body substances. The researchers carefully measured the activity level of ALAD in the red blood cells of pregnant women and their fe-tuses.

Warns Pregnant Women "These measurements showed that

the inhibition of ALAD was greater in smoking mothers and their in-fants than in nonsmoking mothers and their infants. This inhibition apparently is due to increased blood lead levels," Dr. Paul Kuhnert says.

"Pregnant women who smoke expose themselves and their infants to higher concentrations of lead than exist in their environments. This increased exposure results in decreased activity levels of ALAD.

"It also may be inferred that lead

DR. BEAVEN (Continued from Page 1)

training at NIH as a Grants Asso-ciate with the Division of Research Grants after which she was named special assistant to the associate director of Extramural Programs in the National Institute of Arth-ritis, Metabolism, and Digestive Diseases.

In the fall of 1973 Dr. Beaven was appointed biomedical health programs advisor in the Office of the Assistant Secretary of Health, HEW.

There she was responsible for a variety of staff assignments focus-ing on the coordination of inter-agency Public Health Service bio-medical health programs and issues on liaison with other Federal and private agencies having health interests.

In March 1975 she was promoted to serve as assistant to the execu-tive secretary of the HEW Secre-tary's Review Panel on New Drug Regulation. In June 1976 she be-came the executive secretary of the Panel.

Dr. Beaven returned to NIH in November 1976 as special assistant to the Director of NHLBI.

Gordon J. Klovdahl, executive officer. National Institute of General Medical Sciences, retired June 3 from the Fed-eral Government after 37 years of service, 12 of which were spent with NIGMS. During his career, he was the recipient of the DHEW Superior Serv-ice Award.

may inhibit the activity of ALAD in other body tissues, such as the liver and kidneys where it helps synthesize other hemoproteins."

Although lead can cause brain damage in children, Dr. Rosen says it is unknown whether the levels found in mothers and their infants due to smoking are high enough to cause damage.

Additional studies are now taking place on the Perinatal Clinical Re-search Center to determine whether the levels measured represent a significant health hazard.

"One thing is for sure, we know it can't be doing them any good," Dr. Rosen said.

THE NIH RECORD June 28,1977 Page 5

Honors and Awards Ceremony Held Yesterday m

Mr. Gordon Dr. McMillan Dr. Dvorak Dr.Kwon-Chung Ms. Mattheis

Dr. Miller Dr. Webb Dr. Decker Dr. Ross Mr. Boretos Dr. Bialy Mr. Hcdetniemi Dr. Sadler

HONORS AND AWARDS CEREMONY (Continued from Page 1)

"For pioneering efforts in biomedical research grant administration and dedicated service in fostering programs of the NLM, NIH, and PHS."

CHARLES M. GOLDSTEIN, chief, Computer Technology Branch, Lister Hill National Center for Biomedical Communications, "For leader-ship of a nationally recognized program to explore and develop innovative computer applications for libraries and computer-based education."

LILLIAN R. KOZUMA, assistant head, Cataloging Section, Technical Services Division, "For leadership provided in the development and im-plementation of an on-line data base (CATLINE), which serves the nation's medical librarians."

NATIONAL CANCER INSTITUTE NORMA R. GOLUMBIC, senior science editor, Office of Cancer Com-

munications, "For sustained superior performance in creating NCI's major program documents, which because of her work, present complex, controversial and emotional issues credibly, authoritatively, and read-ably."

DR. JEFFREY SCHLOM, microbiologist, Tumor Virus Detection Sec-tion, Division of Cancer Cause and Prevention, "In recognition of leader-ship in the field of breast cancer virology research."

DR. MAXINE F. SINGER, head, Nucleic Acid Enzymology Section, Division of Cancer Biology and Diagnosis, "For crucial rule in formulat-ing, and explaining to the scientific communty and lay public, guidelines for pursuing research involving recombinant DNA molecules."

ELIZABETH W. STROUD, personnel officer, Office of Administrative Management, "For excellent performance in directing NCI's personnel operations during a period of rapid growth."

NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

DR. ROBERT L. DIXON, supervisory pharmacologist, Intramural Re-search Program, Environmental Toxicology Branch, "For contributions to the definition and development of the NIEHS research program, espe-cially those involving transplacental toxicity of hormonally-active en-vironmental chemicals."

DR. DAVID G. HOEL, supervisory mathematical statistician, Intra-mural Research Program, Environmental Biology, "For spearheading research in statistical techniques for assessment of risk associated with human exposure to environmental chemicals and efforts to provide reso-lution to risk assessments."

NATIONAL HEART, LUNG, AND BLOOD INSTITUTE TAVIA GORDON, statistician, Biometrics Research Branch, Division

of Heart and Vascular Diseases, "For sustained, innovative biostatistical contributions to the epidemiology of cardiovascular diseases, including the development of fundamental data resources and powerful methods for estimating cardiovascular risk."

DR. GARDNER C. McMILLAN, associate director for Etiology of Arteriosclerosis and Hypertension, Division of Heart and Vascular Diseases, "For leadership concerning the problems of atherogenesis and creative and critical input into NIH-wide issues."

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

DR. JAMES A. DVORAK, research microbiologist, Laboratory of Parasitic Diseases, "For innovative and developmental research on intra-cellular parasites, including delineation of the interaction of malaria parasites and red blood cells."

DR. KYUNG JOO KWON-CHUNG, research microbiologist, Clinical Mycology Section, Laboratory of Clinical Investigation, "For significant contributions to fungal genetics particularly demonstration of sexual reproductive cycles for certain pathogenic fungi."

MARTHA MATTHEIS, microbiologist, Microbiology and Infectious Diseases Program, Infectious Disease Branch, "For organizational abil-ities and skillful administration of programs related to the clinical eval-uation of respiratory and other infectious disease vaccines."

DR. LOUIS H. MILLER, head, Malaria Section, Laboratory of Para-sitic Diseases, "For outstanding research on the interaction of malaria parasites and red blood cells and for leadership of the Malaria Section, Laboratory of Parasitic Diseases, NIAID."

DR. ALFRED M. WEBB, chief, Program Planning and Projection Staff, "For skill in developing innovative approaches to the projection of new NIAID programs related to the socio-economic impact of allergic and infectious diseases." NATIONAL INSTITUTE OF ARTHRITIS, METABOLISM, AND DIGESTIVE DISEASES

DR. JOHN L. DECKER, chief, Arthritis and Rheumatism Branch, "For original investigations and leadership in cooperative advancement of both the quality and quantity of rheumatologic research."

FRANCIS L. MILLS, executive officer, "For exemplary leadership and genuine sense of public service in biomedical research administration."

DR. PHILIP D. ROSS, research chemist, Section on Physical Chem-istry, Laboratory of Molecular Biology, "For unique studies of the ther-modynamics and other physicochemical characteristics of interaction of biologically important macromolecules." DIVISION OF RESEARCH SERVICES

JOHN W. BORETOS, physical scientist, Chemical Engineering Section, Biomedical Engineering and Instrumentation Branch, "For extraordinary imagination, physical and biological insight, and technical skill in devel-oping and providing biomaterials support to the NIH." NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

DR. GABRIEL BIALY, chief, Contraceptive Development Branch, Center for Population Research, "For establishing and directing, with remarkable skill and dedication, a national program for the development of new contraceptives."

JOEL R. HEDETNIEMI, executive officer, "For outstanding ability as an administrator, superior performance in all aspects of management, and dedicated service to the NICHD."

DR. WILLIAM A. SADLER, chief, Population and Reproduction Grants Branch, Center for Population Research, "For scientific and managerial achievements in directing population research grants and for developing a national network of population research centers."

(Continued on Page 6)

Page 6 June 28,1977 THE NIH RECORD

Recipients of PHS Commendation Medal are: NIH Director's Awards

Dr. Kupferberg Dr. Ludlow

Dr. Hisooka Mr. Demmerle Ms. McGinniss Dr. Vermess

(Continued from Page 5)

NATIONAL INSTITUTE OF NEUROLOGICAL AND COMMUNICATIVE DISORDERS AND STROKE

DR. HARVEY J. KUPFERBERG, pharmacologist, Epilepsy Branch, Neurological Disorders Program, "For abilities in the field of antiepilep-tic pharmacology and innovative techniques in measuring antiepileptic drugs and their metabolites employing mass spectrophotometry."

DR. CHRISTY L. LUDLOW, speech pathologist, Communicative Dis-orders Program, "For superior achievement in developing vigorous extra-mural and clinical research programs to help handicapped persons afflicted with speech and language problems."

DR. EUGENE STREICHER, health scientist administrator, Funda-mental Neurosciences Program, "For superior accomplishments in the development and management of research programs in the areas of neural growth and regeneration and nerve cell biology."

ALBERT A. WOLF, JR., electronics engineer, Epilepsy Branch, Neurological Disorders Program, "For dedication and ability to apply electronic knowledge to the field of epilepsy in the areas of video record-ing and telemetering of EEG."

NATIONAL INSTITUTE OFDENTAL RESEARCH DR. K. KENNETH HISAOKA, deputy associate director for Extra-

mural Programs, "For sustained superior performance as a scientist administrator, especially for his role in the development of effective pro-gram workshops."

DIVISION OF COMPUTER RESEARCH AND TECHNOLOGY ALAN M. DEMMERLE, chief, Computer Systems Laboratory, "For

strong and sustained leadership in the development of specialized com-puter systems that have strengthened research in laboratories and clinics throughout the NIH."

CLINICAL CENTER MARY H. McGINNISS, research biologist, Immunology Section, Blood

Bank Department, "For major contributions to the field of immunohema-tology as investigator, consultant, and teacher."

DR. MICHAEL VERMESS, senior staff radiologist, Diagnostic Radiol-ogy Department, "For outstanding research endeavors and achievements in the field of diagnostic radiology."

DR. DONALD S. YOUNG, chief, Clinical Chemistry Service, Clinical Pathology Department, "For eminent leadership in clinical chemistry, superb computerized compilation of the effects of drugs on clinical lab-oratory tests and dedication to the Clinical Chemistry Service, NIH."

NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES DR. BYRON B. CLARK, director, Pharmacology-Toxicology Program,

"For demonstrated leadership in assembling all aspects of pharmacology and bio-related chemistry into one coordinated, administrative unit, the Pharmacology-Toxicology Program."

FORMER NIH EMPLOYEE DR. BERNICE E. EDDY, retired former NIH employee, "For origi-

nal work on the characterization of polyoma virus and SV40 as tumor-genic agents."

DR. BERNARD TALBOT, Medical Director, Special Assistant for Intramural Affairs, Office of Intramural Affairs, OD, "In recognition of outstanding dedication and continued superior performance in support of administration of the intramural programs and of NIH activities in DNA recombinant molecule research."

DR. PETER J. FISCHINGER, Medical Director, Senior Surgeon (Research), Virus Control Section, Laboratory of Viral Carcinogenesis, DCCP, NCI, "In recognition of leadership in the field of viral oncology research."

DR. MITCHELL H. GAIL, Senior Surgeon, medical statistical re-searcher, Clinical and Diagnostic Trails Section, DCCP, NCI, "For imaginative applications of statistical methods to problems in cell biology and clinical research."

DR. RICHARD J. HODES, Senior Surgeon, head, Immunotherapy Section, DCBD, NCI, "For creative and precise investigations delineating the nature of cellular interactions and mechanisms controlling respon-siveness, cell cooperation and suppression during in vitro immuno re-sponses."

BARBARA H. DENNIS, Senior Dietitian, nutritionist, Lipid Me-tabolism Branch, Division of Heart and Vascular Diseases, NHLBI, "For outstanding contributions to international collaborative research in nutrition and cardiovascular disease and superior dedication and under-standing required to foster a true spirit of international cooperation."

DR. GERALD H. PAYNE, Medical Director, chief, Hypertension Pro-gram, DHVD, NHLBI, "For effective implementation and scientific supervision of a national clinical trial of hypertension therapy involving multiple medical centers and more than 10,900 patients."

DR. RALPH A. FREW, Dental Director, assistant to the associate director, National Caries Program, NIDR, "For continued superior per-formance in biomedical research administration, and for outstanding contributions to the development and management of the National Caries Program, NIDR."

DR. JOHN F. GOGGINS, Dental Director, associate director for Col-laborative Research, NIDR, "For excellence in administration of the NIDR collaborative research activities and in the initiation of programs in unexplored areas of dental research and development."

DR. ANTHONY A. RIZZO, Dental Director, special assistant for pro-gram coordination, Extramural Programs, NIDR, "For unique contribu-tions and outstanding service as Special Assistant for Program Coordina-tion and for innovative approaches to the coordination of categorical program activities."

DR. PHILLIP G. NELSON, Medical Director, chief, Behavioral Biol-ogy Branch, NICHD, "For effective leadership and for encouraging a

Dr. Young

Dr. Fischinger Dr. Gail

Dr. Payne Dr. Frew Dr. Goggins Dr. Rizxo

THE NIH RECORD June 28,1977 Page 7

PHS COMMENDATION MEDALS, EEO, AND SPECIAL AWARDS GIVEN (Continued from Page 6)

multifaceted research program in neurobiology which has led to studies not heretofore possible."

DR. WESLEY H. BRADLEY, Medical Director, director, Communica-tive Disorders Program, NINCDS, "For excellence in the creative de-velopment and direction of a productive extramural research program of the highest technical quality in the communicative disorders area."

DR. JAMES J. CEREGHINO, Senior Surgeon, neurologist, Neurologi-cal Disorders Program, Epilepsy Branch, NINCDS, "For contributions to the NINCDS epilepsy research program as Project Officer for the Epilepsy Branch Antiepileptic Drug Study at New Castle State Hospital, Indiana."

DR. PAUL M. HOFFMAN, Senior Surgeon, medical officer, Laboratory of Central Nervous System Studies, Intramural Research Program, NINCDS, "For outstanding leadership, courage, and ingenuity in the marshalling of resources, during a major natural disaster on the Island of Guam."

DR. RONALD L. KRALL, Surgeon, staff associate, Neurological Dis-orders Program, Epilepsy Branch, NINCDS, "For assisting in the estab-lishment of the NINCDS Drug Screening Program and for sustained high quality work performance in overseeing its operation."

LUCIA M. ATLAS, Health Services Director, chief, Allergy and Infectious Diseases; and Arthritis, Metabolism, and Digestive Diseases, Social Work Sections, Social Work Department, CC, "For sustained high quality of comprehensive social service to patients and families and creative and imaginative leadership in developing the Social Work De-partment's unique medical record system."

MARY R. EMERSON, Dietitian Director, therapeutic research dietitian, Nutrition Department, CC, "For contributions in planning and successfully implementing many tedious and complicated dietary con-trols for a number of studies initiated by the NINCDS."

DR. HARVEY R. GRALNICK, chief, Hematology Service, Clinical Pathology Department, CC, "For very significant contributions to patient care within the Clinical Center, research into the structure and function Factor VIII and dedication to teaching."

A. EILEEN MURNIN, Dietitian Director, therapeutic research dieti-tian, Nutrition Department, CC, "For contributions to the successful implementation of nutrition research orders and services to the Technicon System at the Clinical Center in 1976."

DR. WILLIAM A. EATON, Senior Surgeon, medical officer, Section on Spectroscopy and Structure, Laboratory of Chemical Physics, NIAMDD, "For contributions made in understanding the molecular nature of sickle cell disease."

Dr. Nelson Dr. Bradley Dr. Cereghino Dr. Hoffman Dr. Krall Dr. Porter Dr. Murphy Dr. Wyatt Dr. McPherson

Mr. Dunsmore Mr. Metz Dr. Wagner

DR. ROGER J. PORTER, Senior Surgeon, senior research associate, Neurological Disorders Program, Epilepsy Branch, NINCDS, "For sus-tained high quality performance in assisting in the establishment, organ-ization, and implementation of the Clinical Epilepsy Research Program at the NIH Clinical Center."

DR. BRIAN R. MURPHY, Senior Surgeon, senior research investiga-tor, Respiratory Virus Section, Laboratory of Infectious Diseases, NIAID, "For significant contributions to scientific understanding of the genetics of influenza viruses and to application of this knowledge to immunoprophylaxis."

DR. RICHARD G. WYATT, Senior Surgeon, medical officer, Epidemi-ology Section, Laboratory of Infectious Diseases, NIAID, "For significant contributions to the study of viral gastroenteritis, including development of animal models and cultivation of a gastroenteric pathogen."

DR. CHARLES W. McPHERSON, Veterinary Officer Director, direc-tor, Animal Resources Program Branch, DRR, "For outstanding service in administering an extramural program in Laboratory Animal Science, and in addressing the shortage of nonhuman primates for biomedical research."

DONALD J. DUNSMORE, Senior Sanitary Engineer, assistant to the chief, Environmental Safety Branch, DRS, "In recognition of the devel-opment of a comprehensive evaluation system of NIH programs, with attendant methodology, to assess their impact upon the environment."

HOWARD D. METZ, Senior Sanitary Engineer, assistant chief, Tech-nical Services Section, DRS, "For creative application of engineering skill, managerial ability, and personal dedication to program leadership and staff development for effective maintenance, utilization, and repair of scientific equipment."

DR. WILLIAM M. WAGNER, Health Services Officer, deputy radia-tion safety officer, DRS, "For sustained superior work performance and leadership in the NIH Radiation Safety Program during a period of increasing demands without proportional manpower increase."

Dr. Gralnick Ms. Murnin Dr. Eaton Dr. Campbell

Dr. Fredrickson and Dr. Brown recognized Dr. Iain C. Campbell for his "initiation, courage, and heroic and selfless action of rescuing a co-worker from a pool of sulphuric acid in his Building 10 laboratory on Feb. 24." Dr. Campbell, a Visiting Fellow from Scotland, is employed in the NIMH Clinical Neuropharmacology Branch.

The NIH EEO Award of the Year will be presented to Laura M. Ruby, administrative officer, General Services Management, Division of Administrative Services, for "demonstrating a high degree of commit-ment to the EEO Program and diligent efforts which resulted in increased promotional opportunity for lower-graded DAS employees and an im-proved working environment for many DAS employees."

The NIH EEO Award of the Year will be awarded posthumously to Dr. George M. Willis, former health scientist administrator, NCI. Mrs. Willis will accept the award for her late husband.

The award citation reads "for selfless dedication and outstanding contributions to the NIH Minority Extra-mural Programs — these significantly helped to place the NIH minority programs on their current high level of achievement and made it possible to chart future goals."

The newly-established Harvey J. Bullock, Jr., Award for Equal Opportunity Achievements will be presented to Mary L. White, janitor, DAS. Her award citation reads "for leadership and special services in upholding employee rights which are established through negotiated union contracts and for tireless efforts to build a more responsive employee-oriented relationship with union offi-

cials at the NIH." Mrs. Bullock will assist in the presentation of the award honoring her

late husband, a former NIH employee. Forty Year Length-of-Service Awards will be presented to four staff

members: Walter Chakwin, OD; Ralph Flaherty, OD; Dr. Joseph Leiter, NLM; and Richard J. Colton, NCI.

Page 8 June 28,1977 THE NIH RECORD

Dr. Michael Frank, MAID Section Head, Made Lab Chief, Clinical Director

Dr. Frank has served on the NIH Medical Board and as chairman of the Complement Working Committee.

Dr. Michael M. Frank has been appointed chief of the Laboratory of Clinical Investigation and clini-cal director of the National Insti-tute of Allergy and Infectious Dis-eases, replacing Dr. Sheldon Wolff.

Dr. Frank has headed the Clini-cal Immunology Section of LCI since 1971. In this position he car-ried out basic research programs

•while serving as a pediatrician in the NIH Clinical Center.

A native of New York City, Dr. Frank attended the University of Wisconsin as a Ford Foundation Scholar. He earned his A.B. degree in 1956 and his M.D. from Harvard Medical School 4 years later.

After completing his internship at Boston City Hospital he served as a resident in pediatrics at Johns Hopkins Hospital.

A commissioned officer in the U.S. Public Health Service, Dr. Frank came to NIH in 1962 as a Clinical Associate in the National Institute of Mental Health. After 2 years he returned to the Johns Hopkins School of Medicine to com-plete his residency in pediatrics.

Visits Mill Hill From 1965 to 1966 he was in

England as a visiting scientist at the National Institute for Medical Research in Mill Hill, London, and returned to NIH in 1966 as a senior investigator for the National In-stitute of Child Health and Human Development. In 1968, Dr. Frank moved to NIAID

Dr. Frank's research interests are the mechanisms of immune damage and the clinical aspects of immunopathology.

In 1975, he was awarded the Meritorious Service Medal of the PHS for "outstanding laboratory and clinical research, particularly on hereditary angioedema and on the role of the complement system

Dr. Elliott Siegel Joins Lister Hill Center, Aids Info. Retrieval Prototype

Dr. Elliot R. Siegel has been ap-pointed to the staff of the Office of the Director, Lister Hill National Center for Biomedical Communica-tions, a component of the National Library of Medicine. Dr. Siegel is part of a team that is creating a "prototype computerized informa-tion transfer system." System Is Model

This model system would provide authoritative, up-to-date informa-tion derived from research and clinical practice in a language and format useful to health profes-sionals.

Dr. Siegel received his B.A. de-gree in psychology in 1964 from Brooklyn College, City University of New York, his M.A. in psychol-ogy in 1966 from Michigan State University, and his Ph.D. in com-munications from Michigan State University in 1969.

A staff member of the American

As scientific affairs officer. Dr. Siegel was responsible for coordinating the APA's activities in the area of science and public policy.

Psychological Association since 1970, Dr. Siegel was manager and executive editor of the publications development department, where he launched the Journal Supplement Abstract Service, an innovative formal publication and document distribution system.

Dr. Siegel has served as associate editor of the journal, American Psychologist, and as chairman of the behavioral and social sciences division of the American Society for Information Science. He was a member of the advisory committee to the National Science Foundation Study on the Publisher-Library Relationship.

in defense against disease." In addition, Dr. Frank has been

active in training Clinical Asso-ciates at NIAID. He organized and assumed major responsibility for the clinical electives for medical students in immunology in 1971.

The author of more than 100

Asbestos Fiber Risk Meeting Held June 8

Prompted by concern over the possible effects of asbestos-contain-ing rock (serpentine), Montgomery County Executive James P. Gleason requested that NIH host a meeting to discuss its use as a ground cover for some county roads and play-grounds.

The June 8th meeting in Wilson Hall, chaired by Dr. Donald S. Fredrickson, NIH Director, in-cluded local, state, and Federal officials, experts in various related disciplines, and extensive press coverage.

Director Quoted In his opening remarks, Dr.

Fredrickson stated that "the degree of risk is not possible to assess . . . except to say that there is a high probability of danger after expo-sure. We need more information." The meeting did not attempt to establish any guidelines.

Dr. Irving J. Selikoff of Mt. Sinai School of Medicine and an inter-nationally renowned expert on asbestos-related disorders high-lighted data on exposure to the mineral. He pointed out that there are no known minimum standards for exposure to asbestos.

EPA Recommends Once the fibers get into the lungs,

they are there to stay. However, in incidences where exposure to as-bestos is high, the higher the rate of disease.

The Environmental Protection Agency has recommended that the county temporarily discontinue use of the rock and close playgrounds until it can be determined if any danger does exist from this type of exposure.

Bond Campaign Extended; Results To Be Announced

The NIH Federal U.S. Sav-ings Bond Campaign has been extended.

The final result of the cam-paign—along with the winners of the R&W-donated raffle prizes—will be announced in the next issue of the NIH Record.

The raffle drawing and awarding of the prize for the canvasser having the best cam-paign record will take place in the office of NIH Associate Director for Administration Leon Schwartz, this year's campaign chairman.

scientific publications, Dr. Frank is an associate editor of the Journal of Immunology and was on the American Association of Immunol-ogists Program Committee from 1970 to 1974.

Dr. Betty Pickett Joins NIA as Assoc. Director Of Extramural Research

Dr. Betty H. Pickett has been appointed as the first associate director for Extramural and Col-laborative Research of the National Institute on Aging.

The NIA Extramural and Col-laborative Research Program ad-ministers research grants, research career development awards, insti-tutional research training grants, postdoctoral research fellowships, and research and development con-tracts in the field of aging.

Before joining NIA, Dr. Pickett was a senior staff member of the National Institute of Mental Health for 14 years.

Since 1974, she has served as director of that Institute's two major research support divisions. From 1974 to 1975, she directed the Division of Special Mental Health Programs; from 1975 until her NIA appointment, she headed the

Dr. Pickett was the third woman to receive a Ph.D. in psychology from Brown University. In January 1972 she was awarded the HEW Superior Service Award, and in 1975 she won the HEW Distinguished Service Award.

Division of Extramural Research Programs at NIMH.

Prior to 1974, Dr. Pickett held positions in the extramural pro-grams of NIMH, including execu-tive secretary of the Research Career Program from 1963 to 1966, chief of the Cognition and Learning Section and assistant chief of the Behavioral Sciences Research Branch from 1966 to 1968, and deputy director of the Division of Extramural Research Programs from 1968 to 1974.

Dr. Pickett's move to NIA is a resumption of her service at NIH, which began in 1957 when she joined the Division of Research Grants, serving first as executive secretary of the Behavioral Sci-ences Study Section and later as executive secretary of the Experi-mental Psychology Study Section.

U. S. GOVERNMENT PRINTING OFFICE: 1977 241-163/18