KREBS CYCLECitric Acid Cycle

BEFORE THE CYCLE BEGINS:► Pyruvate turned into acetate gives off CO2

and causes NAD+ NADH►Coenzyme A attaches to acetate acetyl CoA

KREBS CYCLE In the mitochondrial matrix. Acetyl CoA combines with Oxaloacetate (4-C acid)

to make Citrate (6-C acid) Coenzyme A released.

Enzymes rearrange 6-C acid to make 5-C acid. This releases CO2 and turns NAD+ to NADH

Enzymes change 5-C acid to a 4-C acid. CO2 is released and more NADH is formed

Enzymes rearrange 4-C acid twice. Makes one ATP and one FADH2. ATP if formed with help of GTP (GDP GTP.)

Enzymes convert 4-C acid into oxaloacetate. NADH is formed.

Cycle repeats

RESULTS: 2 molecules of CO2 are released 3 molecules of NAD+ are converted to

3NADH 1 molecule of ADP is converted to ATP with

the help of GTP FAD is converted to FADH2 Remember: 2 molecules of pyruvate from

glycolysis so multiply above results by 2