How to start-up @KU Leuven ? Bart De Moor

Academic education

Scientific research

Service to the community

= knowledge and technology transfer to society to industry

KU Leuven - 4000 researchers & 1500 faculty, 800 MEUR Gasthuisberg 1300 researchers, 800 MEUR LERU (League of 22 European Research Intensive Universities)

coordination centre Thomson-Reuters ranking of most innovative universities: - Ranked 16th worldwide - Ranked 2nd Europe

Funding

Type of research (basic to applied)

Size

of p

roje

ct (s

mal

l to

larg

e)

FWO

FP7

IOF Kennisplatformen Hefboomprojecten Mandaten

Innovation-project EU

IDEAS PEOPLE COOPERATION SMEs CIP

OT

IDO

GOA IWT O&O

IWT - OZM

IWT - SBO

IWT SBO voortraject (m. f.)

Computational Biology Genomic data fusion NGS data analysis Graphical models & kernels

Applications Diagnosis of genetic disorders Disease gene discovery Disease management

Methodology Matrix/tensor algebra Classification and survival Multimodal Signal Processing & Analysis

Optimization in engineering Support vector machines & kernel methods

Advanced process control Datamining, information retrieval & knowledge discovery

Complex networks & nonlinear systems Numerical linear algebra

Bioinformatics/Computational Biology Biomedical Data Processing

Digital Signal Processing for Audio & Telecom

Audio Speech processing Speech Communications Public Address Systems Hearing Aids/Cochlear Implants

Digital Communications Wireline ADSL/VDSL Wireless

Systems, Models & Control

IWT Projects: SBO: 2;

Proeftuin:1

Fundamental Strategic Demand-driven

N.A. N.A.

N.A. N.A.

Projects: 13

Research

BELSPO IUAP: 2 ; VLIR: 2

Fellowships: PhD: 4; Postdoc: 6

IWT Fellowships phd: 10 IMEC: fellowships: 1

iMinds Medical IT 2014 SBO: 1

BOF

N.A.

FOD Kankerplan: 1

N.A. FLANDERS

CARE

FL. Care Demo Project: 1

IWT Baekeland: 1 IWT innovation postdoc: 1

KU Leuven centra

IOF Projects: 2: 2KP

Hercules collaborations: 3

KU Leuven topfacilities Genomics Core

SyBioMA

LICT, LMTC LBioSCENTer

IWT Projects: TBM: 4; O&O: 2; Eurostars: 1

iMinds Medical IT ICON: 3; Fallrisk , Nxt Sleep, b-SLIM

Projects: EU:5; ERC:3 ; MC ITN:3 ; EFRO Interreg:1 ; COST: 2;

ERASMUS:1

DYSCO

Projects 8: GOA: 2; PF: 2; BIL: 2; VES:1 Fellowships: DBOF PDM:2 CoE/PF

GOA

MaNet http://www.esat.kuleuven.be/

bioinformatics/software.php

http://homes.esat.kuleuven.be/ ~biomed/software.php

software

VLK: 1

VSC: TIER1:2

Industry: 1

BESTCOM

http://homes.esat.kuleuven.be/http://www.rein-art.eu/highwind/

Academic education

Scientific research

Service to the community

= knowledge and technology transfer to society to industry

Research collaboration

(22)

advice contract R&D projects with government support (IWT, EC, etc.)

Intellectual property rights

(10)

intellectual property rights licensing

Spin-off & innovation

(10)

spin-off creation & growth networks & regional dev. KU Leuven Association

Finance, HR & logistics

(39)

financial administration HRM administration

Management (2)

IPTEC Award

2006 Stanford 2007 Tsinghua 2008 Leuven

Booming business

114 million euro income from research collaboration 1,774 new agreements (2014)

0

200

400

600

800

1000

1200

1400

1600

1800

2005 2006 2007 2008 2009 2010 2011 2012 2013 2014

463

598 812

981 1051

1263 1301

1724

1563

1774

Patents & Intellectual property

129 patent applications in 2014 586 active patent families 42 PCTs

87 million euro license-income Granted patent is often the basis for setting up a

spin-off company

In numbers 2014

Reported findings 177

Priority submissions 129

New patents 52

Examples of technology transfer

PresenterPresentation NotesSpin-off: (foto links boven) LMS Internation is a world leader in computer supported dynamic analysis (acoustics, vibration, sustainability). First spin-off K.U.Leuven Research Group Mechanics (Werktuigkunde), founded in 1979.

Research collaboration (foto rechts boven): Collaboration between Samsonite and prof. Ignaas Verpoest (Leuven-Materials Research Centre) for the development of extremely light but strong suitcases. The Cosmolite suitcases of Samsonite only weigh half of what simular suitcases made from classic materials weigh. Lighter suitcases allow to save on fuel during transportation.

Spin-off: Materialise (foto links onder) has the largest number of rapid prototyping & manufacturing (=3D-printing) machines gathered in one place, in the world. Materialise develops prototypes based on the 3D-printing process (= a laser beam is used lawerwise to print an object, because a layer of powder or resin is hardened by the beam). Based on these prototypes, customers of Materialise can check their design in a tangible way. In addition to prototypes, the 3D-printing process can be used to produce end products such as design objects or lights. 3D-printing enables the use of very complex shapes, that cant be produced with classis techniques. Materialise also develops 3D-printing software and focuses on medical and dental image processing and surgery simulation.

License (foto onder midden) The main component of Atripla (=anti-HIV drug) was discovered at the Leuven Rega Institute for Medical Research. Gilead has taken a license on Atripla and put it on the market.

Spin-off (foto rechts onder): Better3Fruit developt new fruit varieties. The Kanzi-appel is an example of a new variety.

Basic

Research

Strategic

Valorisation Patents Licenses

BOF

IOF FP6/7

SME

Direct Contract Research

KUL Research

group

spinoff NV

FFF BA/VC

founders employees

Fase 1

Creating a spin-off company

Fase 2

http://www.leuveninc.com/profiles/BF_COMP/view.asp?Q=BF_COMP_4149http://www.leuveninc.com/profiles/BF_COMP/view.asp?Q=BF_COMP_4149

Gemma Frisius Fund KU Leuven (GFF) o Seed capital for spin-off companies o GFF founded in 1997 & GFF II in 2002

At the end of 2009 GFF and GFF II merged into one single fund

o Partners: KU Leuven (20% of capital) Two banks: KBC Private Equity (40%) and BNP Paribas Fortis Private

Equity (40%)

o Combination between: Knowledge and technology transfer expertise

(university) Financial expertise (financial partners)

o Not restricted to one technology domain o 27 million euro invested in 42 spin-off

companies

Seed money

Leverage

0

20

40

60

80

100

120

1981 1983 1985 1987 1989 1991 1993 1995 1997 1999 2001 2003 2005 2007 2009 2011 2013

Cumulative number of spin-offs created

Total no. of active spin-offs

Total no. of spin-offs

105 spin-off companies started, 87 still active; together +/- 4,100 employees (numbers 2014)

760 million euro external capital (2005-2014 only) 7 successful flotations (IPOs)

Impact of spin-offs

Engineering

Micro-electronics & ICT

Our jewels

Consultancy

Biomedical

Our jewels (cted)

Yesterdays closing dinner Cartagenia: Founders & investors

Student entrepreneurs

Leuven Community for innovation Driven Entrepreneurship

LRD

GFF

Leuven.Inc

Science Parks

KU Leuven

Industry

Region Financial world

The Leuven biotope

Critical mass of high quality research & projects Multidisciplinary team & high value support Favourable entrepreneurial climate within the university Clear incentives to encourage researchers Instruments and networks that support technology

transfer & entrepreneurship Legal context in Flanders The Leuven eco-system & biotope: Leuven MINDGATE

Succes factors

Leuven MINDGATE

Slide Number 1Slide Number 2Slide Number 3FundingSlide Number 5Slide Number 6Slide Number 7Slide Number 8Slide Number 9IPTEC Award Booming businessPatents & Intellectual property Examples of technology transferSlide Number 14Slide Number 15Slide Number 16Slide Number 17Slide Number 18Slide Number 19Slide Number 20Slide Number 21Slide Number 22Slide Number 23Slide Number 24Slide Number 25