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Prevent diabetes problems
Keep your kidneys healthy
Number 3
in a Series
of 7
US Department of Health and Human Services
NATIONAL INSTITUTES OF HEALTH National Diabetes Information Clearinghouse
Prevent diabetes problemsKeep your kidneys healthy
US Department of Health and Human Services
NATIONAL INSTITUTES OF HEALTH National Diabetes Information Clearinghouse
ContentsWhat are diabetes problems 1
What should I do each day to stay healthy with diabetes 2
What do my kidneys do 3
How can I prevent diabetes kidney problems 4
How can my doctor protect my kidneys during special x-ray tests 6
How can diabetes hurt my kidneys
What can I do if I have kidney problems
7
caused by diabetes 9
How will I know if my kidneys fail 10
What happens if my kidneys fail 11
Will I know if I start to have kidney problems 13
How can I find out if I have kidney problems 13
Pronunciation Guide14
For More Information 15
More in the Series 18
Acknowledgments 19
vi
What are diabetes problems Too much glucose in the blood for a long time can cause diabetes problems This high blood glucose also called blood sugar can damage many parts of the body such as the heart blood vessels eyes and kidneys Heart and blood vessel disease can lead to heart attacks and strokes You can do a lot to prevent or slow down diabetes problems
Ureters
Kidneys
Bladder
Your kidneys are two bean-shaped organs about the size of your fist They are located just below the rib cage near your back
1
What should I do each day to stay healthy with diabetes
Follow the healthy eating plan that you and your doctor or dietitian have worked out
Be active a total of 30 minutes most days Ask your doctor what activities are best for you
Take your medicines as directed
Check your blood glucose every day Each time you check your blood glucose write the number in your record book
Check your feet every day for cuts blisters sores swelling redness or sore toenails
Brush and floss your teeth every day
Control your blood pressure and cholesterol
2
Donrsquot smoke
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Prevent diabetes problemsKeep your kidneys healthy
US Department of Health and Human Services
NATIONAL INSTITUTES OF HEALTH National Diabetes Information Clearinghouse
ContentsWhat are diabetes problems 1
What should I do each day to stay healthy with diabetes 2
What do my kidneys do 3
How can I prevent diabetes kidney problems 4
How can my doctor protect my kidneys during special x-ray tests 6
How can diabetes hurt my kidneys
What can I do if I have kidney problems
7
caused by diabetes 9
How will I know if my kidneys fail 10
What happens if my kidneys fail 11
Will I know if I start to have kidney problems 13
How can I find out if I have kidney problems 13
Pronunciation Guide14
For More Information 15
More in the Series 18
Acknowledgments 19
vi
What are diabetes problems Too much glucose in the blood for a long time can cause diabetes problems This high blood glucose also called blood sugar can damage many parts of the body such as the heart blood vessels eyes and kidneys Heart and blood vessel disease can lead to heart attacks and strokes You can do a lot to prevent or slow down diabetes problems
Ureters
Kidneys
Bladder
Your kidneys are two bean-shaped organs about the size of your fist They are located just below the rib cage near your back
1
What should I do each day to stay healthy with diabetes
Follow the healthy eating plan that you and your doctor or dietitian have worked out
Be active a total of 30 minutes most days Ask your doctor what activities are best for you
Take your medicines as directed
Check your blood glucose every day Each time you check your blood glucose write the number in your record book
Check your feet every day for cuts blisters sores swelling redness or sore toenails
Brush and floss your teeth every day
Control your blood pressure and cholesterol
2
Donrsquot smoke
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
ContentsWhat are diabetes problems 1
What should I do each day to stay healthy with diabetes 2
What do my kidneys do 3
How can I prevent diabetes kidney problems 4
How can my doctor protect my kidneys during special x-ray tests 6
How can diabetes hurt my kidneys
What can I do if I have kidney problems
7
caused by diabetes 9
How will I know if my kidneys fail 10
What happens if my kidneys fail 11
Will I know if I start to have kidney problems 13
How can I find out if I have kidney problems 13
Pronunciation Guide14
For More Information 15
More in the Series 18
Acknowledgments 19
vi
What are diabetes problems Too much glucose in the blood for a long time can cause diabetes problems This high blood glucose also called blood sugar can damage many parts of the body such as the heart blood vessels eyes and kidneys Heart and blood vessel disease can lead to heart attacks and strokes You can do a lot to prevent or slow down diabetes problems
Ureters
Kidneys
Bladder
Your kidneys are two bean-shaped organs about the size of your fist They are located just below the rib cage near your back
1
What should I do each day to stay healthy with diabetes
Follow the healthy eating plan that you and your doctor or dietitian have worked out
Be active a total of 30 minutes most days Ask your doctor what activities are best for you
Take your medicines as directed
Check your blood glucose every day Each time you check your blood glucose write the number in your record book
Check your feet every day for cuts blisters sores swelling redness or sore toenails
Brush and floss your teeth every day
Control your blood pressure and cholesterol
2
Donrsquot smoke
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
vi
What are diabetes problems Too much glucose in the blood for a long time can cause diabetes problems This high blood glucose also called blood sugar can damage many parts of the body such as the heart blood vessels eyes and kidneys Heart and blood vessel disease can lead to heart attacks and strokes You can do a lot to prevent or slow down diabetes problems
Ureters
Kidneys
Bladder
Your kidneys are two bean-shaped organs about the size of your fist They are located just below the rib cage near your back
1
What should I do each day to stay healthy with diabetes
Follow the healthy eating plan that you and your doctor or dietitian have worked out
Be active a total of 30 minutes most days Ask your doctor what activities are best for you
Take your medicines as directed
Check your blood glucose every day Each time you check your blood glucose write the number in your record book
Check your feet every day for cuts blisters sores swelling redness or sore toenails
Brush and floss your teeth every day
Control your blood pressure and cholesterol
2
Donrsquot smoke
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
What are diabetes problems Too much glucose in the blood for a long time can cause diabetes problems This high blood glucose also called blood sugar can damage many parts of the body such as the heart blood vessels eyes and kidneys Heart and blood vessel disease can lead to heart attacks and strokes You can do a lot to prevent or slow down diabetes problems
Ureters
Kidneys
Bladder
Your kidneys are two bean-shaped organs about the size of your fist They are located just below the rib cage near your back
1
What should I do each day to stay healthy with diabetes
Follow the healthy eating plan that you and your doctor or dietitian have worked out
Be active a total of 30 minutes most days Ask your doctor what activities are best for you
Take your medicines as directed
Check your blood glucose every day Each time you check your blood glucose write the number in your record book
Check your feet every day for cuts blisters sores swelling redness or sore toenails
Brush and floss your teeth every day
Control your blood pressure and cholesterol
2
Donrsquot smoke
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
What should I do each day to stay healthy with diabetes
Follow the healthy eating plan that you and your doctor or dietitian have worked out
Be active a total of 30 minutes most days Ask your doctor what activities are best for you
Take your medicines as directed
Check your blood glucose every day Each time you check your blood glucose write the number in your record book
Check your feet every day for cuts blisters sores swelling redness or sore toenails
Brush and floss your teeth every day
Control your blood pressure and cholesterol
2
Donrsquot smoke
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
What do my kidneys do The kidneys act as filters to clean the blood They get rid of wastes and send along filtered fluid The tiny filters in the kidneys are called glomeruli
When kidneys are healthy the artery brings blood and wastes from the bloodstream into the kidneys The glomeruli clean the blood Then wastes and extra fluid go out into the urine through the ureter Clean blood leaves the kidneys and goes back into the bloodstream through the vein
Glomeruli (tiny filters in the kidney)
Ureter (wastes and fluid go out in urine)
Vein (clean blood leaves the kidney)
Artery (blood and wastes enter the kidney)
You have two kidneys Your kidneys clean your blood and make urine This drawing shows a cross section of a kidney
See page 14 for tips on how to say the words in bold type
3
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
How can I prevent diabetes kidney problems Keep your blood glucose as close to your goal as
you can For many people this level is as close to normal as possible For others a higher blood glucose goal may be better Ask your doctor what blood glucose numbers are healthy for you
Keep your blood pressure below 13080 to help prevent kidney damage Blood pressure is written with two numbers separated by a slash For example 12070 is said as ldquo120 over 70rdquo
For some people a higher blood pressure goal may be better Ask your doctor what numbers are best for you If you take blood pressure pills every day take them as your doctor tells you Keeping your blood pressure under control will also slow down or prevent damage to your eyes heart and blood vessels
Keep your blood pressure under good control
4
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Ask your doctor if you should take pills to slow down kidney damage Two kinds are available bull ACE (angiotensin-converting enzyme)
inhibitor
bull ARB (angiotensin receptor blocker) Follow the healthy eating plan you work out with
your doctor or dietitian If you already have kidney problems your dietitian may suggest you cut back on protein especially animal products such as meat milk cheese and eggs
Have your kidneys checked at least once a year by having your urine tested for protein This test is called the urinary albumin test
Have your blood tested at least once a year for creatinine The result of this test should be used to find your glomerular filtration rate (GFR) a measure of kidney function
Pills can help you control your blood pressure and slow down kidney damage
5
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Have any other kidney tests your doctor thinks you need
Avoid taking painkillers regularly Daily use of pills like aspirin or acetaminophen can damage the kidneys Taking a single dose of aspirin every day to protect the heart however should be safe Taking acetaminophen for occasional pain should also be safe But if you are dealing with chronic pain such as arthritis work with your doctor to find a way to control your pain without putting your kidneys at risk
See a doctor right away for bladder or kidney infections You may have an infection if you have these symptoms bullpain or burning when you urinate bull a frequent urge to go to the bathroom bull urine that looks cloudy or reddish bull fever or a shaky feeling bull pain in your back or on your side below the ribs
How can my doctor protect my kidneys during special x-ray testsX-ray tests using a contrast agent pose a risk to your kidneys If you need x rays your doctor can give you extra fluid and medicine before and after the x rays to protect your kidneys Or your doctor may decide to order a test that does not use a contrast agent
6
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
How can diabetes hurt my kidneys When the kidneys are working well the tiny filters in your kidneys the glomeruli keep blood proteins inside your body You need these proteins to stay healthy
High blood glucose and high blood pressure damage the kidneysrsquo filters When the kidneys are damaged proteins leak out of the kidneys into the urine The urinary albumin test detects this loss of protein in the urine Damaged kidneys do not do a good job of filtering out wastes and extra fluid Wastes and fluid build up in your blood instead of leaving the body in urine
Kidney damage begins long before you notice any symptoms An early sign of kidney damage is when your kidneys leak small amounts of a protein called albumin into the urine But the only way to know about this leakage is to have your urine tested
With more damage the kidneys leak more and more protein More and more wastes build up in the blood This damage gets worse until the kidneys fail
Diabetic kidney disease (DKD) is the medical term for kidney problems caused by diabetes DKD affects both kidneys at the same time
7
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Healthy kidney
No albumin a protein is leaking from the healthy kidney
Unhealthy kidney
Ureter (wastes and fluid)
Artery (blood and wastes)
Vein (clean blood)
Ureter (wastes fluid and protein)
Vein (blood with waste products)
Albumin
Artery (blood and wastes)
Albumin a protein is leaking from the healthy kidney
8
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
What can I do if I have kidney problems caused by diabetesOnce you have kidney damage you can slow it down or stop it from getting worse by controlling your blood glucose and blood pressure Taking an ACE inhibitor or an ARB is important for both controlling your blood pressure and reducing kidney damage However if you are pregnant you should not take an ACE inhibitor or ARB
If you have diabetes you should have your urine and blood tested regularly to see how well your kidneys are working The test results should be given to you as your urine albumin and GFR results
Keeping blood pressure under control helps to keep your kidneys healthy
9
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
How will I know if my kidneys fail At first you cannot tell Kidney damage from diabetes happens so slowly that you may not feel sick at all for many years You will not feel sick even when your kidneys do only half the job of normal kidneys You may not feel any signs of kidney failure until your kidneys have almost stopped working However getting your urine and blood checked every year can tell you how well your kidneys are working
Once your kidneys fail you may feel sick to your stomach and tired all the time Your hands and feet may swell from extra fluid in your body
You may feel sick to your stomach when your kidneys stop working
10
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
What happens if my kidneys fail One way to treat kidney failure is with dialysis Dialysis is a treatment that does some of the work your kidneys used to do Two types of dialysis are available (see page 12) You and your doctor will decide what type will work best for you
Dialysis is a treatment that takes waste products and extra fluid out of your body
11
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
1Hemodialysis In hemodialysis your blood flows through a tube from your arm to a machine that filters out the waste products and extra fluid The clean blood flows back to your arm
2Peritoneal dialysis In peritoneal dialysis your belly is filled with a special fluid The fluid collects waste products and extra water from your blood Then the fluid is drained from your belly and thrown away
Another way to treat kidney failure is to have a kidney transplant This operation gives you a new kidney The kidney can be from a close family member friend or someone you do not know A new kidney must be a good match for your body You may be on dialysis for a long time because many people are on a waiting list for a new kidney from donors they do not know You are more likely to have a kidney transplant if you know someone who is able to donate a kidney to you
12
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Will I know if I start to have kidney problems Not likely You will know you have kidney problems if your doctor checks your blood for creatinine to measure your GFR and your urine for albumin Do not wait until you feel ill to have your blood and urine checked for signs of DKD
How can I find out if I have kidney problems Two lab tests can tell you and your doctor how well your kidneys are working
Each year make sure your doctor checks a sample of your urine to see if your kidneys are leaking small amounts of albumin
At least once each year your doctor should check your blood to measure the amount of creatinine Creatinine is a waste product your body makes If your kidneys are not cleaning waste products from your blood they can build up and make you sick Your doctor can use your creatinine level to check your GFR Results of this test tell you how well your kidneys are removing wastes from the blood
13
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Pronunciation Guide albumin (al-BYOO-min)
angiotensin (AN-jee-oh-TEN-sin)
artery (AR-tur-ee)
creatinine (kree-AT-ih-neen)
dialysis (dy-AL-ih-siss)
glomerular (gloh-MAIR-yoo-lur)
glomeruli (gloh-MAIR-yoo-ly)
hemodialysis (HEE-moh-dy-AL-ih-siss)
inhibitor (in-HIB-ih-tur)
peritoneal (PAIR-ih-toh-NEE-uhl)
14
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
For More Information Diabetes Teachers (nurses dietitians pharmacists and other health professionals)
To find a diabetes teacher near you call the American Association of Diabetes Educators toll-free at 1ndash800ndashTEAMUP4 (1ndash800ndash832ndash6874) or look on the Internet at wwwdiabeteseducatororg and click on ldquoFind a Diabetes Educatorrdquo
Dietitians
To find a dietitian near you contact the American Dietetic Association at wwweatrightorg and click on ldquoFind a Nutrition Professionalrdquo
Government
The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is part of the National Institutes of Health (NIH) To learn more about kidney problems write or call NKUDIC 3 Information Way Bethesda MD 20892ndash3580 1ndash800ndash891ndash5390 or see wwwkidneyniddknihgov on the Internet
The National Kidney Disease Education Program (NKDEP) is part of the NIH To learn more about kidney problems write or call NKDEP 3 Kidney Information Way Bethesda MD 20892 1ndash866ndash454ndash3639 or see wwwnkdepnihgov on the Internet
15
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
To get more information about taking care of diabetes contact
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
National Diabetes Education Program 1 Diabetes Way Bethesda MD 20814ndash9692 Phone 1ndash888ndash693ndashNDEP (1ndash888ndash693ndash6337) TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndepmailnihgov Internet wwwndepnihgov
American Diabetes Association 1701 North Beauregard Street Alexandria VA 22311 Phone 1ndash800ndashDIABETES (1ndash800ndash342ndash2383) Internet wwwdiabetesorg
16
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Juvenile Diabetes Research Foundation International 26 Broadway 14th Floor New York NY 10004 Phone 1ndash800ndash533ndashCURE (1ndash800ndash533ndash2873) Fax 212ndash785ndash9595 Email infojdrforg Internet wwwjdrforg
National Kidney Foundation 30 East 33rd Street New York NY 10016 Phone 1ndash800ndash622ndash9010 Internet wwwkidneyorg
17
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
More in the Series The Prevent Diabetes Problems Series has seven booklets that can help you learn more about how to prevent diabetes problems
For free single copies of these booklets write call fax or email the
National Diabetes Information Clearinghouse 1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov
These booklets are also available at wwwdiabetesniddknihgov on the Internet
18
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
Acknowledgments Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts The National Diabetes Information Clearinghouse (NDIC) thanks the people who helped review or field-test the original version of this publicationFor the American
Association of Diabetes Educators
Lynn Grieger RD CDEArlington VTCelia Levesque RN
CDE Montgomery AL Teresa McMahon
PharmD CDE Seattle WA Barbara Schreiner RN
MN CDE Galveston TX
For the American Diabetes Association
Phyllis Barrier MS RD CDE
Alexandria VA Linda Haas PhC RN
CDE Seattle WA Kathleen Mahoney
MSN RN CDE Drexel Hill PA Randi Kington MS
RN CS CDE Hartford CT
For the Centers for Medicare amp Medicaid Services
Baltimore MDJan Drass RN CDE
For the Diabetes Research and Training Centers
Albert Einstein School of Medicine
Norwalk Hospital Norwalk CT Jill Ely RN CDE Sam Engel MD Pam Howard APRN CDE
Indiana University School of Medicine
Indianapolis IN Madelyn Wheeler MS
RD FADA CDE
VAJDF Diabetes Research Center
Vanderbilt School of Medicine
Nashville TN Ok Chon Allison
MSN RNCS ANP CDE
Barbara Backer BS James W Pichert PhD Alvin Powers MD Melissa E Schweikhart Michael B Smith Kathleen Wolffe RN
For the Grady Health System Diabetes Clinic
Atlanta GAErnestine Baker RN
FNP CDE Kris Ernst RN CDE Margaret Fowke RD LD Kay Mann RN CDE
For the Indian Health Service
Albuquerque NMRuth Bear RD CDEDorinda Bradley RN
CDE Terry Fisher RN Lorraine Valdez RN
CDE
Red Lake MN Charmaine Branchaud
BSN RN CDE
For the Medlantic Research Center
Washington DC Resa Levetan MD
For the Texas Diabetes Council
Texas Department of Health
Austin TX Luby Garza-Abijaoude
MS RD LD
The NDIC also thanks Katherine R Tuttle MD FASN FACP of the Providence Medical Research Center Sacred Heart Medical Center in Spokane WA and the University of Washington School of Medicine in Spokane and Seattle for reviewing the updated version of this publication
19
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
National Diabetes Information Clearinghouse
1 Information Way Bethesda MD 20892ndash3560 Phone 1ndash800ndash860ndash8747 TTY 1ndash866ndash569ndash1162 Fax 703ndash738ndash4929 Email ndicinfoniddknihgov Internet wwwdiabetesniddknihgov
The National Diabetes Information Clearinghouse (NDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) The NIDDK is part of the National Institutes of Health of the US Department of Health and Human Services Established in 1978 the Clearinghouse provides information about diabetes to people with diabetes and to their families health care professionals and the public The NDIC answers inquiries develops and distributes publications and works closely with professional and patient organizations and Government agencies to coordinate resources about diabetes
This publication is not copyrighted The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired
This publication is available at wwwdiabetesniddknihgov
This publication may contain information about medications When prepared this publication included the most current information available For updates or for questions about any medications contact the US Food and Drug Administration toll-free at 1ndash888ndashINFOndashFDA (1ndash888ndash463ndash6332) or visit wwwfdagov Consult your doctor for more information
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010
US DEPArTmENT OF HEALTH AND HUmAN SErvICES National Institutes of Health
NIH Publication No 10ndash4281 February 2010