AmCham Denmark’s Analytical Instruments Committee is pleased to announce the 18th annual Executive Seminars in Analytical Chemistry: ESAC 2018.

ESAC brings together manufacturers, leading scientific researchers, progressive vendors and cutting-edge technology within the field of analytical instruments.

Experiences, methods, results and the latest developments will be presented within four core areas: Life Science / Biotech, Pharmaceutical, Food / Environmental and Clinical / Forensic applications.

ANALYTICAL INSTRUMENTS COMMITTEE COMPANIES

Event Coordinator:AmCham DenmarkDag Hammarskjölds Allé 132100 Copenhagen

KEYNOTE SPEAKER

Quantification of Microplastic in Environmental MatrixesBy Professor Jes Vollertsen, Aalborg University, Denmark.

Microplastic is everywhere – in our water, air, soil, and food. It is an emergent issue threatening human and en-vironmental health. Little is known on the occurrence and fate of microplastic, partly because the issue is new and partly because microplastic is rather difficult to analyze for. In this emerging research field, AAU has established a strong laboratory for detecting microplastic, including ac-quiring two Agilent Cary’s 620/670 FTIR Imaging systems with 128 pixel FPA’s. This presentation will address how we use FTIR imaging to detect microplastic down to the a few micrometers in size.

Jes Vollertsen is Professor of Environmental Engineering and leads the section of Water and Environment at Aal-borg University, Denmark. He has primarily worked with biological, chemical and physical processes in polluted ur-ban and rural aquatic systems. He leads a research group on microplastic consisting of 5 full-time microplastic re-searchers and affiliated students and lab technicians. The main focus of the microplastic research is on developing and improving analytical methods for its quantification in environmental matrixes. He has authored many scientific publications, here of 95 published in Web of Science listed publications.

Wednesday, April 11, 2018 - Scandic Copenhagen

GUEST EXHIBITOR REGISTRATION:To register, visit www.esac.dk by April 4.

Participation is free of charge (Continental breakfast, lunch, coffee & soft drinks will be provided)

No cancellations after: April 4 (thereafter, cancellations & ‘no shows’ will be invoiced for DKK 500 (ex. VAT).

Keynote speakerProfessor Jes Vollertsen

Professor of Environmental Engineering & Head of the Water and Environment sec-tion at Aalborg University, Denmark.

09:00 - 09:45 Registration & Coffee09:45 - 10:00 Introduction & Welcome by Stephen Brugger, AmCham Denmark10:00 - 10:35 Keynote Speaker: "Quantification of Microplastic in Environmental Matrixes", Jes Vollertsen, Professor of Environmental Engineering & Head of the Water and Environment section, Aalborg University, Denmark

Life Science/Biotech Pharmaceutical Food/Environmental Clinical/ForensicTitle Presentation by Technique Presentation by Technique Presentation by Technique Presentation by Technique

10:45 - 11:15 Quantitative Peptide Mapping by LC MS (a.k.a. MAM) in Bio- pharmaceutical Development – Examples from the Industry

Dan Bach Kristensen, Symphogen

LC-MS-MS Analysis of Extractable and Leachable (E&L) Compounds Using a Low-Energy EI-Capa-ble High Resolution Accurate Mass GC/Q-TOF

PeterAbrahamsson,Agilent

GC-HRAM-MSMS

10 Seconds MS/MS Analysis by Thermal Laser Desorption – Quantitative Analysis of Androstenone and Skatole

Birgitte Winther Lund, Danish Technological Institute, DMRI

MS-MS Estradiol measure-ment by 2D-LC-MS/MS

Anne Schmedes,Vejle Sygehus

2D-LC-MS

11:15 - 11:45 Coffee Break

11:45 - 12:15 CESI-MS – A New tool for the BioPharma Industry for Detection of Modification Sites of Biopharmaceuticals

Whitney Smith, Sciex

CESI-MS Successful Generic Approaches for Heart-cutting 2D-LC withFocus on User Friend-liness

Isabelle François, Waters

2D-LC Metabolic Engineering of Plant Natural Prod-ucts for Food – High throughput Analytics of Small Metabolites and Targeted Proteomics by LC-MS/TQ Assistant Professor for Metabolic Engineering Head of MS-Analytics

ChristophCrocoll, Dept. of Plant and Environ. Sciences University of Co-penhagen

Separation and Quantification of En-antiomers of Amphet-amine-Related Drugs and Their Structural Isomers using Agilent 1260 SFC/6495 QQQ System

PeterAbrahamsson,Agilent

LC-MS-MS

12:20 - 12:50 In-depth Proteomics Analysis by Ion Mobility High Resolution QTOF MS”

Allan Stensballe, Section forBiomedicine,AalborgUniversity

IMS-MS “The Doctor Never prescribed Irgafos” - Analytical Workflows for Extractables &Leachables

Kyle D’Silva, Thermo Fisher Scientific

LC-MS/MS, ICP-MS and GC-MS

HPLC-QTOF-MS/MS Guided Discovery of Microbial NaturalProducts

ChristopherPhippens, DTU

LC-MS-MS Testing for Rye-phyto-chemicals in Prostate Tissue, Plasma, and Urine from Prostate Cancer Patients.

Stine K.Steffensen, AarhusUniversitetFlakkebjerg

LC-MS-MS

12:50 - 13:50 Lunch Break

Life Science/Biotech Pharmaceutical Food/Environmental Clinical/ForensicTitle Presentation by Technique Presentation by Technique Presentation by Technique Presentation by Technique

13:50 - 14:20 Development and Dif-ferent Uses of Peptide Mapping in thePharmaceutical Industry

Gunhild Klarskov KristiansenAGC Biologics

LC Absolute Quantification of Host Cell Proteins in Biopharmaceuticals by SWATH LC MS/MS

Ejvind Mørtz, Alphalyse

SWATH LC MS/MS

Application of GC- Orbitrap mass spec-trometry for ultra-trace analysis of organo-chlorine contaminants in Antarctic penguin blood

Nicholas Warner, NILU-Norsk Insti-tutt for luftforsking

GC-MS Routine Use of the Toxtyper for General Unknown Screening of Oral Fluid and Urine Samples in Toxicology

MichaelBoettcher, Dept.Toxicology MVZ Labor Dessau GmbH

14:25 - 14:55 Bioenergetics Analysis of Peripheral Blood Mononuclear Cells (PB-MCs) as a Clinical Test for Mitochondrial Dys-function: a Step towards Mitochondrial Medicine

Paula Fernandez Guerra, Aarhus Universitet

The Road to New Enzymatic Strategies for Characterization of O-glycosylated Proteins

Fredrik Olsson, CEO, Genovis AB

High Resolution LC-MS

Investigating Pome-granate Juice Nu-tritional and Quality Characteristics Using Ion Mobility and a Novel DIA Analysis Mode on a QTof MS Instrumentation

JoanneConnolly,Waters

IMS-MS HRAM Quantitation, How, When and Why

Magnus Olin, Thermo Fisher Scientific

LC-MS/MS

15:00 - 15:30 Coffee Break, Wrap up & Prize Drawing