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Appendicitis in the adult, pediatric, and pregnant population
Kimberly Henry, RNC, FNP-SSUNY Institute of Technology
Nursing 652
Thought to be obstruction of appendiceal lumen↓
Inflammation ↓
Ischemia↓
Perforation↓
Abscess formation or Generalized Peritonitis
Pathophysiology
Etiology of the obstructionPediatrics
Lymphoid hyperplasia due to infections
Adults
Fecaliths (hard fecal masses)
Calculi Benign or malignant
tumors
1st degree relative with history of appendicitis
10-19 year old age group
Male (2:1)
Intra-abdominal tumors
Parasites
Risk Factors
Classic presentation consists of vague periumbilical pain which later migrates to RLQ as inflammation progresses (within 4-48hrs)
May or may not have a fever Anorexia Nausea or/or vomiting (after the onset of pain) Pain which is exacerbated by walking or coughing Nonspecific signs: indigestion, flatulence, bowel
irregularity, diarrhea, generalized malaise
Adult Patient Presentation:Subjective data
May have tachycardia and hypertension r/t pain and fever
May display shallow breathing in an attempt to not cause pain
Psoas sign: Pain when right thigh is extended (retrocecal appendix) as a result, patient may lie with knee bent to relieve tension on ilopsoas muscle
Positive rebound tenderness
Objective data
Rovsing sign: RLQ pain when palpating LLQ
Obturator sign: Right hip and knee flexed, then rotated internally stretching obturator muscle (pelvic appendix)
McBurney’s sign: Pressure applied to McBurney’s Point
Bowels sounds can be present, absent, or decreased
Symptoms can be dependent on location of
the tip of appendix
Retrocecal appendix: may only produce dull abdominal tenderness but marked pain during rectal/pelvic exam
Anterior appendix: Produces marked, localized pain in the right lower quadrant
Pelvic appendix: Causes tenderness below McBurney’s point. Also will have pain during rectal/pevic exam
GI: Gastroenteritis, IBD, Divertulitis, Ileitis, Cholecystitis, Pancreatitis, bowel obstruction, Intussusception, Crohn’s Disease,
Gynecological: PID, Ectopic Pregnancy, Ruptured Ovarian Cyst, Tubo-Ovarian Cyst, Ovarian and Fallopian Torsion, Mittelschmerz, Endometriosis, Acute Endometritis
Urological: Testicular Torsion, Epididymitis, Renal Colic, kidney stones, Prostatitis, Cystitis, Pylenephritis
Differential Dx
CBC with Diff: mild to moderate leukocytosis (10-20,000mcg/L) with a left shift of immature neutrophils
U/A: may show hematuria and/or pyuria C-Reactive Protein (CPR)- elevation in CPR
coupled with leukocytosis can be an indicator of appendicitis
CT scan is the most widely used imaging modality, but should be used only when diagnosis is uncertain
Ultrasound is reliable to confirm, not exclude, the diagnosis
Laboratory Tests and Diagnostic Imaging
Migratory right iliac fossa pain 1pt Anorexia 1pt Nausea/Vomiting 1pt Tenderness in RLQ 2pts Rebound tenderness 1 pt Fever >37.3 1 pt Leukocytosis 2pts Shift to the left 1 pt
1-4 discharge 5-6 observation/admission >7 surgery
Alvarado Scoring System
The standard of care for treating appendicitis is appendectomy
Preop: NPO, IV fluids, IV antibiotics Cefoxitin (1-2gms)Cefazolin (2g if <120kg 3g if >120kg)PCN and Cephalosporin allergy Clindamycin
900mg plus Gentamycin 5mg/kg
Management/Treatment Guidelines
Less likely to present with classic appendicitis signs
Due to the enlarging uterus, McBurney’s Point may be located more toward the mid or upper right side of the abdomen
Rebound tenderness and guarding may not be present (due to uterus size)
An increased WBC is a normal finding in pregnancy, with the count rising to ~25,000 during labor
Different subjective and objective data of the pregnant patient
Lack of migratory pain in 50% of patients Absent of anorexia, with 50% reporting they are
hungry Infants may be lethargic, have increased irritability
with movement, and may flex their hips for comfort
Hoping on one foot or coughing usually elicits abdominal pain
Neonates display temperature instability May limp or have right hip pain May have right sided pelvic pain or mass on
palpation or rectal exam
Different subjective and objective data of the pediatric patient
The adult list plus: Intussusception Intestinal Malrotation Torsion of the Omentum Hemolytic Uremic Sydrome Primary Peritonitis Henoch-Schonlein Purpura Sickle cell-disease UTI
Differential Diagnosis in the Pediatric Patient
Perforation Sepsis Shock Death
Peds: Rupture earlier and have a rupture rate of 15-60%
Pregnant patients: 40% rupture rate and fetal mortality rate of 2-8.5%
Geriatrics: Rupture rate of 67-90%
Complications of Appendicitis
Wound infection (increased risk if no prophylactic antibiotics)
Intestinal obstruction Paralytic Ileus Incisional Hernia Preterm labor
Complications of Surgery
No heavy lifting (>10 lbs) or strenuous physical activity for 4-6 weeks
May return to work 1-2 weeks S/S infection
Follow-up/counseling/education
References: