Upload
kimberly-taylor
View
71
Download
0
Embed Size (px)
Citation preview
KIMBERLY MICHELLE TAYLOR
2917 Rogers Dr, Falls Church, VA 22042
[email protected], (571) 451-3500
Summary
Searching for a position in computational biophysics or bioinformatics
Data analysis, data mining and biostatistics
Experience in programming and algorithm development
Finite element analysis and FDTD EM simulation
Molecular simulation using NAMD, VMD and CHARMM
Protein thermodynamics and kinetics, including differential scanning calorimetry, circular
dichroism, UV/VIS spectroscopy and protein purification (FPLC, HPLC, column
chromatography)
Teaching, writing, presentations
Education
2014-2017 M.S. Bioinformatics, George Mason University
GPA 4.0/4.0
1997-2005 Ph.D. Biophysics, University of Wisconsin-Madison
Howard Hughes Predoctoral Fellowship (1997-1999), NIH Molecular Biophysics
trainee (1998-2003) GPA 3.83/4.0
1994-1997 M.A. Biophysics, Johns Hopkins University
Howard Hughes Predoctoral Fellowship (1994-1997) GPA
3.22/4.0
1991-1994 B.S. Physics (Highest Distinction), University of Virginia
Echols Scholar, University Achievement Scholarship, Barry S. Goldwater Scholarship, Phi Beta Kappa, Sigma Xi (Associate Member), Sigma Pi Sigma GPA 3.82/4.0
Experience
December 2015-September 2016
Postdoctoral Associate, Baylor College of Medicine, Houston, TX
PIs: Professor Stuart Corr and Dr. Steven Curley
Performed FDTD simulations of RF device for thermal heating of tumors
Used differential scanning calorimetry (DSC) to measure heat capacity and thermal conductivity of organs, tissues and tumors
Provided data analysis and research support to other projects
Skills: FDTD simulation using Sim4Life, differential scanning calorimetry, permittivity measurements, data analysis using Python, RStudio, Excel and JMP Pro
Kimberly Taylor, Ph.D.
Page 2 of 5
August 2014- present
Graduate student, George Mason University, Manassas, VA
Courses:
o Fall 2014: BINF 634 (Bioinformatics Programming), BINF 641 (Molecular Modelling)
o Spring 2015: BINF 631 (Bioinformatics Methods), BINF 702 (Biological Data Analysis),
BINF 730 (Biological Sequence/Genome Analysis)
o Fall 2015: BINF 650 (Introduction to Databases for Bioinformatics), BINF 690
(Numerical Methods for Bioinformatics), BINF 702 (Bioinformatics Colloquia)
Skills: Perl and Python programming, R and RStudio, molecular simulation using NAMD,
VMD and CHARMM
August 2009-March 2011
Adjunct professor, Northern Virginia Community College, Alexandria, VA
Course: General Biology I (BIO 101) lecture and laboratory
Prepare and deliver lectures
Administer tests and quizzes
Supervise and assistant with associated laboratory Counsel and tutor students as necessary
March 2009- December 2009, October 2010-March 2011
Adjunct professor, Westwood College, Arlington, VA
Courses: Introduction to Physical Science (SCI 121), Selected Topics in Physics (SCI 321),
Algebra II (MTH 111), Geometry (MTH 211), Prealgebra I and II (MTH 090 and 091)
Prepare and deliver lectures
Administer tests, quizzes and weekly homework assignments
Counsel and tutor students as necessary
2007-2008
Postdoctoral researcher, University of Texas Medical Branch, Galveston, TX
Research advisor: David Gorenstein (Dept. of Biochemistry and Molecular Biology)
Postdoctoral Fellow, Joint Sandia National Laboratories/University of Texas Medical
Branch Bioengineering for Biodefense Initiative
Project: Development of biosensor using thioaptamer and microring resonator
technologies
Work was funded by a grant written by myself through a joint program between Sandia
National Laboratories and the University of Texas Medical Branch
Techniques used: preparation of protein and nucleic acid monolayers on surfaces using
covalent attachment, analysis of surface thickness and composition using ellipsometry
and other techniques, epifluorescence, design and production of microfluidic channels using PDMS, analysis binding/dissolution
Kimberly Taylor, Ph.D.
Page 3 of 5
2005-2007
Postdoctoral researcher, Sandia National Laboratories, Albuquerque, NM
Research Advisor(s): Igal Brener, Darren Branch
Projects: 1) Use of a microring resonator to detect biomolecular binding events; 2) acoustic
focusing for use in miniature cytometry
Techniques used: preparation of protein monolayers on surfaces using adsorption and
covalent attachment, preparation of patterned surfaces using photoresist and masks,
analysis of surface thickness and composition using ellipsometry, epifluorescence, design and production of microfluidic channels using PDMS
Summer 2005
Postdoctoral research associate, Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI
Advisor: Daniel van der Weide
Project: Use of radiofrequency and microwave techniques for detection of protein
conformational change
Techniques used: UV/VIS and dielectric spectroscopies, fluorescence polarization, single channel analysis, antenna design and fabrication
2000-2005
Graduate fellow, Molecular Biophysics, University of Wisconsin-Madison, Madison, WI
Advisor: Daniel van der Weide (Electrical & Computer and Biomedical Engineering)
Thesis title: “Use of Microwave-Resonant Slot Antennas to Detect Protein Conformational
Change”
Techniques used: UV/VIS, and dielectric spectroscopy, fluorescence polarization, single
channel analysis, antenna design and fabrication
1997-1999
Graduate fellow, Molecular Biophysics, University of Wisconsin-Madison, Madison, WI
Advisor: Ronald Raines (Depts. of Biochemistry and Chemistry)
Project: Investigation of the thermodynamics and kinetics of small collagen-like peptides
Techniques used: HPLC, CD and UV/VIS spectroscopy, differential scanning calorimetry, and analytical ultracentrifugation
1994-1997
Graduate student researcher, Johns Hopkins University, Baltimore, MD
Advisor: Peter Privalov (Depts. of Biology and Biophysics)
Projects: 1) Measurement of domain-domain interactions in avian ovomucoids; 2)
calorimetric measurement of cratic entropy
Techniques used: Protein expression and purification by column chromatography and FPLC, CD and UV/VIS spectroscopy, differential scanning calorimetry
Kimberly Taylor, Ph.D.
Page 4 of 5
1993-1994
Undergraduate researcher, University of Virginia, Charlottesville, VA
Advisor: Arthur S. Brill (Dept. of Physics)
Supported by Howard Hughes Undergraduate Biomedical Research Program Project:
Investigation of high- and low-spin Fe3+ in human hemoglobin using
Techniques used: protein purification, UV/VIS spectroscopy
Teaching and Other Professional Experience
2009-2011 Adjunct Professor, Northern Virginia Community College
Course taught: General Biology I
2009-2011 Adjunct Professor, Westwood College
Classes taught: Introduction to Physical Science, Selected Topics in Physics, Algebra II, Geometry, Prealgebra I and II
2006, 2007 Panelist, National Science Foundation Graduate Research Fellowship Program
Evaluation Meeting, Biochemistry, Biophysics & Structural Biology Panel
Department of Biophysics, The Johns Hopkins University
Spring 1995: "Molecular Physiology and Biophysics"
Winter 1996: "Introduction to Electron Microscopy"
Department of Electrical and Computer Engineering, University of Wisconsin-Madison
November 2004: Guest lecture, ECE 602 (Special Topics: Bio-Electronics)
Publications, Presentations and Patents
van der Weide, D.W. and Taylor, K.M. 2011 "Microwave and UV-VIS Forensic Probing of Skeletal
Tissue: Myoglobin as a Marker", Platform talk presented at 2011 Nanoelectric Devices for
Defense & Security Conference, Brooklyn, NY
Ravula, S.K., Taylor, K.M., Lidke, D.S., Oliver, J.M., James, C.D. and Brener, I. 2007 “A
microfabricated flow cytometry system for optical detection of cellular parameters”. Platform talk presented at Biophysics Society 51st Annual Meeting, Baltimore, MD
Taylor, K.M. and van der Weide, D.W. 2005 "Ultra-Sensitive Detection of Protein Thermal
Unfolding and Refolding using Microwave Antennas", IEEE Trans. Microwave Theory Tech. 53: 1576-1586
Taylor, K.M. and van der Weide, D.W. 2005 "Use of Microstrip-Fed Planar Slot Antenna for
Detection of Protein Conformational Change", Platform talk presented at Biophysical Society
49th Annual Meeting, Long Beach, CA van der Weide, D.W., Ramachandran, S., Taylor, KM.,
Son, I.S., Kim, H.S. and Blick, R.H. 2005 "Near-field microwave probing of single-molecule blocking events", Poster presented at
Biophysical Society 49th Annual Meeting, Long Beach, CA van der Weide, D.W., and Taylor,
KM. 2004. "Microwave dielectric spectroscopy method and apparatus" (Patent 6,801,029). Wisconsin Alumni Research Foundation, United States of America.
Taylor, KM. and van der Weide, D.W. 2004. "Ultra-Sensitive Microwave Detection of Protein
Conformational Changes". Presented at June 2004 International Microwave Symposium, Ft.
Worth, Texas and included in 2004 Int. Microwave Symp. Dig.
Taylor, KM. and van der Weide, D.W. 2003. "Microwave sensing of protein conformation and
binding" (invited talk). Presented at March 2003 APS Annual Meeting, Austin, Texas.
Kimberly Taylor, Ph.D.
Page 5 of 5
Taylor, KM. and van der Weide, D.W. 2003. "Combined Microwave and Optical Spectroscopy of
Solution Protein Conformation and Ligand Binding" (poster). Presented at 47th annual
Biophysical Society Meeting, San Antonio, Texas.
Choi, M.K, Taylor, K, Bettermann, A and van der Weide, D.W. 2003. “Spectroscopy with
Electronic Terahertz Techniques for Chemical and Biological Sensing.” Int. J. High Speed
Electron. Syst. 13: 937-950.
Choi, M.K, Taylor, K, Bettermann, A, and van der Weide, D.W. 2002. “Broadband 10-300 GHz stimulus-response sensing for chemical and biological entities.” Phys. Med. Biol. 47: 3777-3787.
Taylor, KM., and van der Weide, D.W. 2001. “Microwave assay for detecting protein
conformation in solution.” In Instrumentation for Air Pollution and Global Atmospheric
Monitoring. (eds. J.O. Jensen, and RL. Spellicy), pp. 137-143. SPIE Press, Boston, MA.
Taylor, KM., and van der Weide, D.W. 2001. “Sensing folding of solution proteins with resonant
antennas.” In 9th International Conference on Terahertz Electronics. (ed. J. Hesler), Charlottesville,
VA.
van der Weide, D.W., Choi, M.K, Taylor, K and Bettermann, A. 2001. “Biological and chemical
contrast for broadband THz sensing.” In 9th International Conference on Terahertz Electronics.
(ed. J. Hesler), Charlottesville, VA.
Bretscher, L.E., Jenkins, CL., Taylor, KM., DeRider, M.L., and Raines, RT. 2001. “Conformational stability of collagen relies on a stereo electronic effect.” JACS. 123: 777-778.
Klink, T.A., Woycechowsky, K.J., Taylor, K.M., and Raines, R.T. 2000. “Contribution of disulfide
bonds to the conformational stability and catalytic activity of ribonuclease A.” Eur. J. Biochem.
267: 566-572.
Holmgren, S.K, Bretscher, L.E., Taylor, KM., and Raines, RT. 1999. “A hyperstable collagen mimic.” Chem. Biol. 6: 63-70.
Holmgren, S.K, Taylor, KM., Bretscher, L.E., and Raines, RT. 1998. “Code for collagen's stability
deciphered.” Nature 392: 666-667.
Other Experience
Software: Sim4Life, JMP Pro, Python, R and RStudio, Perl, NAMD, VMD, Microsoft Office (incl.
Access and PowerPoint), Origin and OriginPro (OriginLab Corp.), NLREG, Adobe Illustrator
and Photoshop, LabView, Advanced Design System 2003A (Agilent Technologies), Sonnet
(Sonnet Software), ChemDraw, Protein Explorer, Molscript, QuB, pClamp, SolidWorks,
MathCAD, ImagePro, EndNote, basic knowledge of PASCAL, C/C ++, FORTRAN 77, Edline, Blackboard
Professional organizations: The Biophysical Society, The Protein Society
Languages: Basic French (speaking, reading, writing)
Interests: Books, music, cooking, knitting