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june 2012 Vol. 40 No. 4 (Serial No. 218) WWW.KSEA.ORG KSEA LETTERS UNDERGRADUATE & GRADUATE SCHOLARSHIPS & YOUNG INVESTIGATOR GRANTS NATIONAL MATHEMATICS & SCIENCE COMPETITION Journal of the Korean-American Scientists and Engineers Association

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Page 1: KSEA LETTERSksea.org/KSEALetters/Vol_40_4_2012.pdf · His research is focused on developing a new method to improve the resolu-tion of fiber orientation maps called R2*-based fiber

june 2012Vol. 40 No. 4 (Serial No. 218)

www.kSea.org

KSEA LETTERS

UndergradUate & gradUate scholarships & YoUng investigator grants

national MatheMatics & science coMpetition

Journal of the Korean-American Scientists and Engineers Association

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1952 Gallows Road. Suite 330 Vienna Virginia U.S.A. | (703) 893-9772 | www.kusco.org

Korea-US Science Cooperation Center Established as a non-profit in 1997 for fostering science & technology cooperation

between the U.S. and Korea through a variety of programs S&T Program

Supporting S&T meetings KUSCO scholarship for Science-majored graduate students KUSCO-NRF-NSF Summer Institute Program National Math and Science Competition

WEST Program

What is WEST program?

The WEST program is an exchange program created between the governments of the U.S. and Republic of Korea. The program will allow qualified university students from Korea to enter the United States for a period up to 18 months as Exchange Visitors on the J-1 visa.

Parties Names and type Major responsibilities Host The US organizations Provide work experience Sponsor KUSCO Visa, Insurance, and administration Participants University students from Korea Travel, housing and living expense

Benefit Comparison between WEST and other J-1 program

Items WEST Program Generic J-1 program Visa KUSCO applies Host applies through sponsors

Program KUSCO provides ESL and placement works Host is responsible for the training program

Cost KUSCO and Participants pay for travel, visa and ESL. No cost to the host.

Host may be responsible for the travel and visa application.

The Current Participating US host institutions

For further information as to WEST program at [email protected]

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table of contents

editorial note 3

Message from the 40th president 4

president of Ksea visits director of bigheart 5

featured articlesExploration of Cellular Galaxy: Search for the Inner Life of the Cell 6 Sequencing the Cancer Genome 8

technical articlesA Quest for the Origin of the Universe 10Neuroimaging to Visualize White Matter Fiber Connections in the Brain 12Many-Body Interactions in Nanostructures 14RF Test Labs Summary 16

UKc 2012 advertisement 17

special project: Global Joint Research Project in Industrial Original Field 20

Ksea-snU ceremony: President Lee Participates at the Start-Up Festival & Signs an MOU with SNU 21

nMsc 2012Summary Report 22

scholarship 2012 Summary Report 24

award ceremony in Washington, d.c. 25

eventsNational Mathematics and Science Competition 26Chapters, APS, Regional Conferences 27

Ksea organizational structure 53

KSEA LETTERS Vol. 40 No. 4 June 2012 1

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individuAL SponSoRS of KSEA

$1,000 <=

Jin Kim($5,700)Chan-Mo Park($5,000)

Hosin Lee($3,000) Israel Jung($3,000)

Esther Yang($3,000)Saeyoung Ahn($2,500)

Chul Ahn ($1,000)Wan-Kyoo Cho($1,000)

Kang-Won Lee ($1,000)Kang-Wook Lee($1,000) Sung Won Lee($1,000) Yoonsoo Park ($1,000)

$500 <= and < $1,000

Yongho Sohn ($750)Rex Havens ($730)Sangil Choi ($500)

Sung-Kwon Kang ($500) Benjamine Lee ($500)Chin Ok Lee ($500)

Insup Lee ($500)Yong Nak Lee ($500)

Sam Ryu ($500)Seri Park ($500)

< $500

Hyun Sam ChoHong T. HahnGye Won Han

Joseph HanChristian Icksoo HongSoojung “Claire” Hur

Eugene HyunBryan Kim

Dongho KimHanseup Kim

Jihie KimJohn J. Kim

Quiesup KimYoohwan Kim

John Chang Hoon LeeKyung T. Lee

Byungyu “Brian” ParkGrace Eunyoung Park

Woonsup ParkJames Song

Jungsook YangLee Joung Yoo

Jang-Hyun Youn

ouTSTAnding pERfoRmAncE of 40Th diREcToRS

General Director Benjamin Lee; Information Technology Director Sung Yi; Young Generation Director II Israel (Sun Min) Jung; Young Generation Director I Byung-Do Kim; Membership Director II Hanseup Kim; Headquarter Operation Director Kyungjae Myung (left-> right, top row) Publication Director II Hyunggun Kim; Finance Director Seri Park; Publication Director III Jae Yu; Technical Group Director Eun-Suk Seo; Membership Director III JungAh Jung (left-> right, middle row) Executive Director Yongho Sohn; President Hosin “David” Lee (left-> right, bottom row)Not pictured: President-Elect Hyung-Min Michael Chung; Vice President I Kookjoon Ahn; Vice President II Hee-Koo Moon; Publication Director I Byungkyu “Brian” Park; Membership Director I Youngsoo Park

in recognition of

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KSEA LETTERSVol. 40 No. 4 (Serial No. 218)

juNE 2012

Publisher and EditorHosin “David” Lee

Editorial BoardJohn Kim (UCLA)

Philip Kim (Columbia Univ.)Luke Lee (UC Berkeley)

Hongkun Park (Harvard Univ.)

Publications DirectorsByungkyu “Brian” Park

Hyunggun KimJaehoon Yu

Staff EditorEuna Yoon

Staff DesignerYoon Hee Chang

Publication DateJune 2012

Published by the Korean-American Scien-tists and Engineers Association. All rights reserved. No part of this publication may be reproduced, in any form or any means, with-out the prior written permission of KSEA.

KSEA assumes no responsibility for state-ments and opinions expressed in this pub-lication.

EDITORIAL NOTE fOR KSEA LETTERS: JOuRNAL Of ThE KOREAN-AmERIcAN ScIENTISTS AND ENgINEERS ASSOcIATION

This June issue features articles from two world-renowned scholars:

Luke Lee , Arnold and Barbara Silberman Distinguished Professor of Bioen-gineering at UC Berkeley, presented an article titled “Exploration of Cellular Galaxy: Search for the Inner Life of the Cell” and explained about nanoscale molecular imaging of cellular activities and its potential usages as remote optical switches for gene, protein regulations & sensing.

Peter Park is associate professor at Harvard Medical School and features ar-ticle about his laboratory’s project on sequencing the cancer genome. With the improving sequencing technology, he hopes to find detailed charac-terization of the cancer genome, particularly by looking for the “rearrange-ments” these oncogenes tend to possess.

Additional technical articles have been also solicited from:

Dr. Jaehoon Yu is a professor at the University of Texas at Arlington. His article explains how particle physics, specifically with the usages of large de-tectors and powerful accelerators, is applied to explain some of the funda-mental principles of the universe.

Dr. Jongho Lee is assistant professor at the University of Pennsylvania, School of Medicine and received the 2012 KSEA Young Investigator Grant. His research is focused on developing a new method to improve the resolu-tion of fiber orientation maps called R2*-based fiber orientation mapping method, for better visualization of the brain.

Dr. Cheol-Hwan Park, research scientist at the Bosch Research and Technol-ogy Center, is another recipient of the 2012 KSEA Young Investigator Grant. His article explains how many-body interactions bear crucial importance in understanding spectroscopic properties of nanostructures, the research through which he hopes to find new sources of energy, i.e. as solar cells.

Mr. Gene Cho, Ph.D. Candidate at New York University, is the 2012 KSEA Business Venture Challenge winner from YGTLC held in San Francisco. He introduces us to his RF Test Lab, where the research is focused on develop-ing and implementing innovative radio frequency (RF) testing solutions.

This issue also covers:

▶ Highlights of the 2012 KSEA Undergraduate scholarships, KSEA-KUSCO Graduate scholarships, and National Mathematics and Science Competition (NMSC). Detailed information on the scholarship recipients, as well as national statistics on the NMSC are presented to provide you a big picture of these events.

▶ MOU ceremony with Seoul National University R & DB Foundation Office

▶ Award Ceremony to honor the NMSC national winners, KSEA undergraduate schol-arships, and YIG was held at the Marriott Hotel at Tyson’s Corner, located near the nation’s capital, Washington, D.C. Featured were many welcoming and congratulatory speeches from: John Kim, Rockwell Collins distinguished professor at UCLA as well as KSEA editorial board member, Inil Lee, Korean embassy science counselor, Susan Lee, Maryland state delegate, Chung K. Pak, Patent Judge & Maryland higher education commissioner, S. James Gates, Jr., member of President Obama’s Council of Advisors on Science and Technology, Kyong Mi Choi, Chair of the NMSC Commitee, and Seung Jong Lee, President of KUSCO.

▶ Pictures of events organized by local chapters and affiliated professional societies

KSEA LETTERS Vol. 40 No. 4 June 2012 3

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KSEA LETTERS Vol. 40 No. 4 June 20124

Building upon former Presidents’ accomplishments, we are 4,344 members strong which repre-sents more than 30% increase over the previous year. Our budget also increased by more than 20%. We have provided more career enhancing benefits to our members to help them profession-ally in both America and Korea. We are a premier technical society respected by all scientists and engineers that will continue to exist to help its members succeed in the main stream of America.

As the 40th President, I am proud of achievements that directors and the staff have made together for KSEA as noted. However, as a senior faculty member who endeavors to develop careers of ap-prentices, I cannot help but to be excited about all the accomplishments that directors have made for their own personal and professional lives during the 40th administrative term while tirelessly serving the KSEA. I believe that directors must serve the KSEA not only for the administrative duties, but also as role models for its members at various stages of their career and personal lives. Here are several noteworthy accomplishments by the directors that I will remember and cherish.

• Executive Director Yongho Sohn received 2012 UCF Research Incentive Award.• Finance Director Seri Park became an endowed Clare Booth Luce Assistant Professor at Villanova University. • Headquarter Office Director Kyungjae Myung’s received the NIH Director’s Challenge Grant and became an editorial board member of Genome Integrity and Journal of Genomics.• Membership Director 2 Hanseup Kim received both the DARPA Young Faculty Award and the NSF CAREER Award. • Membership Director 3 Jungah Jung was married on December 18, 2011 and is now expecting a baby. • YG Director 1 Byungdo Kim has become the Director of High Performance Computing Center in Advanced Research Com puting at Virginia Institute of Technology.• YG Director 2 Sun Min Israel Jung became a member of the Executive Development Institute for emerging Asian industry leaders and the President of the Boeing Asian American Professionals Association. • Publication Director 2 Hyunggun Kim received an R01 grant award from the NIH and became a father on December 15, 2011.• Publication Director 3 Jae Yu received the Dean’s outstanding research award at University of Texas at Dallas.

I would like to end my statement by quoting words from Dr. Jim Gates, Advisor to KSEA and a member of President Obama’s Council of Advisors on Science and Technology (PCAST), “The development of world-recognized iconic products and processes will rely on communities similar to KSEA community that are able to create an environment where the cultural uniqueness of societies and individuals can be welded to the rigor and demands of science and engineering.”

It has been my honor to serve you all.…

40th KSEA President, Hosin “David” Lee

Message froM the 40th president

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intervieW With dr. lUKe lee

president of Ksea visits director of bigheart[Charles Lee (Alumnus, UC Berkeley KSEA Chapter, Computer Programmer, Luvocracy Inc.) &

Ann Yun (President of UC Berkeley KSEA Chapter)]

On a bright Sunday morning, I met President Hosin Lee in San Francisco and we took the BART to Berkeley together. I have known him for over 26 years but this was the first time he asked for my help. I asked Ann Yun, President of YG Chapter at UC Berkeley, to help me document KSEA President Lee’s interview with Prof. Luke Lee (Prof. Lee), Director of BIGHEART Center at UC Berkeley.

Prof. Lee began by telling us about the Petri dish, invented over a hundred years ago, that has remained essentially unchanged since its inception. In order to perform more accurate experiments faster in a natural condition for culturing, Prof. Lee has devel-oped a way to combine a thousand Petri dishes into one chip. When Prof. Lee was younger, he was busy protecting his ideas – now he says he knows better, “Embrace

people and share your ideas,” he explains, “Even if you lose at the beginning, at the end you’ll win.” Why, you may ask? “If you believe you are creative you’ll create another idea. The later ideas are better anyway.”

Prof. Lee advises young people to enjoy what they do, but also to speak their own minds. “Don’t be shy. I used to be shy,” he says. His current research questions the fundamental biological principles such as mRNA transcription that have been accepted for decades – but while accepted, have never been proven, especially not by one as perspicacious as Prof. Lee.

As he scurried to make sure to hold doors open for us as we walked through his labs, Prof. Lee was remarkably open about his past challenges and failures. His personal philosophy is to be open about failure – hiding failure only makes it harder to learn and grow, he says. He also emphasized that researchers should think about social impact with their research. He currently develops a standalone system to make a cheap and effective blood testing device to quickly detect HIV, tuberculosis and malaria, sponsored by the Bill Gates Foundation, which has the power to affect hundreds of thousands of lives. President Lee was particularly impressed with Prof. Lee’s high ethical standard such as being selective in receiv-ing research funds from corporate sponsors and not using embryonic cell for his research.

After the dinner with local KSEA YG members, Prof. Lee offered to give us a ride to San Francisco using his car. That was the best part of the interview where President Lee was so excited and took a picture of Prof. Lee in his car, exclaiming, “1990 Toyota Corolla with all manual!” I knew why President Lee was so excited since I know he drives 1999 Chevy Tracker with all manual including door locks and windows. President Lee did not hesitate to ask him why he drove such an old car. Prof. Lee answered, “I have better things for the money.” President Lee nodded with a big satisfied smile. After dropping off President Lee at the hotel, he gave me a ride to my office on Sunday night and, then, I have realized why his center was named as BIGHEART.

KSEA LETTERS Vol. 40 No. 4 June 2012 5

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exploration of cellUlar galaxY: search for the inner life of the cell[Luke P. Lee]

Arnold and Barbara Silverman Distinguished Professor, Bioengineering UC Berkeley

Humankind has always been fascinated with space exploration and reaching up to the stars. Scientific discovery and breakthroughs in technology allow us to explore space outside our solar system. Now we are learning how to explore inner life of living cells. By creating biologically inspired optics1-based 3D microscopes and innovative nanocrescent antennae2-based satellite nanoscopes, we can enjoy exploring cellular space of living cells and obtain snapshots of what we metaphorically refer to as the cellular galaxy. Satel-lite nanoscopes can also be used to produce desired changes in proteins and genes.

Satellite nanoscopes are tiny optical antennae integrated with target finder, light sources and optical gene switches. They use a phenomenon known as ‘nanoplasmonics’, which involves the interactions of photon and electron on the surface of metals. These nanoscopes can be placed within living cells or in the space between cells. Nanoscopes with multiple functions (i.e. precise targeting, imaging, gene delivery, and gene regulations) will generate new fundamental knowledge in basic biological science as well as advanc-ing the new field of translational medicine. Despite our understanding of cells as the basic building blocks of life, little is known about the dynamics of their intracellular processes and extracellular communication. The information transferred by signaling molecules depends not only upon their biochemical composition but also upon their spatio-temporal distributions in living cells. It is thus important to measure how the signaling molecules are transmitting their signals within cells as well as between cells, and to obtain ultrafast detection of biomolecule release and of growth factors administrated during different stages of tissue development. Yet, doing this is still a major challenge. To address this challenge, we have been developing nanosatellites for real-time monitoring of dynamic cellular activities in living cells. We will describe three ways in which nanosatellites can be of use: (a) imaging cellular activities3, (b) regulating and sensing gene expression, and (c) creating transcriptional pulses.

real-tiMe nanoscale MolecUlar iMaging of cellUlar activities Our understanding of biological systems is increasingly dependent on our ability to visualize and measure biomolecules and bio-logical events with high spatial and temporal resolution within living cells. Novel cellular and molecular imaging techniques are essential to the advancement of basic life science and translational medicine. The challenge is to develop techniques to noninvasively capture cellular information and resolve dynamic intracellular processes. In response to this challenge we developed satellite nano-scopes capable of specific molecular-level targeting, imaging, and intervention (fig.1).

These nanoscopes will enable high-resolution monitoring of the dynamics of proteins, enzymes, and subcellular or-ganelles without causing dam-age or exogenous artifacts that affect cell function. Current techniques require fluorescent labeling, which has limita-tions and cannot provide the dynamics of molecular finger-print changes. The electron microscope (EM) can resolve subcellular structures without

labeling, but EM irreversibly damages living cells. Moreover, EM and fluorescence imaging cannot provide spectroscopic data (i.e. chemical fingerprints). Our recent accomplishments offer striking advantages over traditional imaging techniques: stability, bio-compatibility, selectivity, and potential for spectroscopic imaging of electronic states of biomolecules in living cells.3

By utilizing satellite nanoscopes, we can obtain snapshots of what we metaphorically refer to as the cellular galaxy. Using optical antennas with specific resonant wavelengths within living cells as well as in the space between cells, we can measure localized bio-chemical features (i.e. structural and kinetic features) by spectroscopic imaging.3 Also, since interactions between nucleic acids and proteins are essential to genetic information processing, the detection of size changes in nucleic acids is the key to mapping. Our nanoplasmonic molecular ruler with subnanometer axial resolution allows for a label-free, quantitative, real-time measurement

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KSEA LETTERS Vol. 40 No. 4 June 2012

Figure 1. (Left) Images of cosmic space galaxy and diverse kind of satellite telescopes vs. (Right) Images of cellular galaxy by biophotonic satellite nanoscopes with multiple functions and innovative designs for selective targeting, sensing, gene delivery, and gene regulations.

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of nuclease activity and also serves as a new DNA footprint-ing platform, which can accurately detect and map the specific binding of a protein to DNA.4 The nanoplasmonic optical an-tenna function as “nanosatellites”, exploratory devices in the living cellular environment for selective targeting, sensing, and gene regulations. Remote controls of localized optical gene de-livery5 and the generation of transcriptional pulses via satellite nanoscopes allows spatio-temporal control of gene regulations on demand and precision molecular level optogenetics for sys-tems biologists and clinicians, while the local dynamic response of chemicals of interest can be investigated with the spectro-scopic sensing functionality.

satellite nanoscopes as reMote optical sWitches for gene, protein regUlations & sensing After performing optical gene regulation5 in living cells by sat-ellite nanoscopes (fig. 2), we can utilize them to capture the images of electron transfer dynamics of some key enzymes. Precise remote control of optical gene regulation and protein expression in living cells is a powerful tool for studying cellular signaling pathways and systems biology. To advance the studies of intracellular & extracellular signaling pathways, we have assembled nanoscale transmitter and receiver systems for remote manipulation of biological systems. Because of their large surface-to-volume ratio, nanoplasmonic gene or protein switches are ideal carriers of oligonucleotides (short nucleic acid sequences). Proteins can also be attached to these optical switches, and we can liberate them at a specific time in order to control the effects of intracellular and extracellular signaling molecules. While attached to their carriers, oligonucleotides are inactive. In the presence of NIR incident light that is matched to the resonance wavelength of gene carrier (i.e. optical antenna of nanosatellite), the formerly bound substance is released, to freely interact with the local environment. Using such gene switches, intracellular genes can be silenced on-demand. Similar methods will be used for the precision delivery of peptides and protein drugs in the extracellular space. Satellite nanoscopes can deliver both extracel-lular and intracellular signaling molecules for the systematic studies of living cells.

creating transcriptional pUlses in living cells Transcription of genes, by which the genetic code written in DNA is transformed into the mobile RNA message, is commonly thought to be a more or less continuous process. However, it can occur in “bursts” or “pulses” within cells depend on the influ-ence of many other factors. Using satellite nanoscopes we will create transcriptional pulses in living cells and understand the mechanism of living systems. Since transcriptional dynamics play important roles in developmental processes, stem cell speciali-zation and cancer progression, precise transcriptional control can provide unparalleled insight into these processes. Using NIR illumination as a remote optical trigger to release free oligonucleotides and ‘activate’ their functionality, repressor and activator genes are silenced on-demand. Creation of transcriptional pulses using satellite nanoscopes lays the foundation for enabling the generation and elucidation of regulated transcriptional dynamics governing normal developmental processes as well as unregu-lated transcriptional dynamics responsible for disease. These multifunctional nanosatellites with targeting, sensing, optical gene switching capability will allow us to study living systems systematically.

In summary, the possibility to use the satellite nanoscopes as light sources, transmitters, and carriers for oligonucleotides, which can be released in response to an optical pulse at a specific wavelength, is exciting and promising. This approach holds enormous power to regulate gene expression in a way that has not been previously possible, such as in the form of “transcriptional pulses” that can switch cellular signaling pathways on or off. The ability to target, sense, modify and control cellular function will have vast implications beyond our imagination.

references1. K. Jeong et al., Science, 312, 557-561 (2006).2. Y. Lu et al., Nano Lett., 5(1), 119-124 (2005).3. G. L. Liu, et al., Nature Methods, 4, 1015-1017 (2007).4. G. L. Liu, et al., Nature Nanotech., 1, 47-52 (2006).5. S. E. Lee, et al., Nano Lett., 9(2), pp 562–570 (2009).

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KSEA LETTERS Vol. 40 No. 4 June 2012

Figure 2. Optical gene regulations by external NIR remote con-trols: (a) antisense DNA, siRNA, or microRNA can be conjugated on nanoplasmonic optical antennas, and then locally released by selective light sources. (b) On-demand gene regulations in living cells. Similar paradigm will be applied for the delivery of peptides and protein drugs in extracellular matrix.

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KSEA LETTERS Vol. 40 No. 4 June 20128

seqUencing the cancer genoMe[Peter J. Park]

Associate Professor, Computational GenomicsHarvard Medical School

The technological advances in DNA sequencing—determining the sequence of nucleotides (A, C, G, or T) that comprise a stretch of DNA—in the past few years have been breathtaking. To sequence the genome of an organism, one typically takes a population of cells, breaks the membrane to obtain the DNA, fractures the DNA into small fragments, prepares them for sequencing, and a sequencer car-ries out specific enzymatic reactions to determine the nucleotide sequences for each fragment. Then, a computational method is used to put the pieces back together into a single long stretch. The perfect machine would sequence a large stretch of DNA (~108 nucleotides for a human chromosome) very quickly. The ‘old’ standard technology can sequence about 103 nucleotides in a row, one fragment at a time. The new technology—often referred to as ‘next-generation sequencing’—can sequence shorter fragments of about 102 nucleotides but more than a billion of fragments at a time. See figure 1 for a popular DNA sequencer from Illumina, Inc. This massively parallel approach has been made possible by a convergence of several technologies, including high-resolution microscopy, miniaturization, and new chemistry for amplification of DNA and labeling and detection of nucleotides. As a result, the cost of sequencing has plunged: the original sequencing of the human genome, completed in 2003, cost of $3 billion dollars; it cost several million dollars just five years ago; and now a human genome can be sequenced, albeit at a lower quality than the original version, for less than $5,000. Many people expect this to be around $1,000 in a few years. Although we focus on the sequencing of individual human genomes below, this technology also has numerous applications in basic biomedical research.

This ‘whole-genome sequencing’ (sequencing of the entire genome rather than, e.g., a small set of genes) generates a massive amount of data. A high-quality human genome is approximately ~300 gigabytes, after reducing from a much larger form of raw data. Several projects in my laboratory involve on the order of 100 genomes, which totals about 30 terabytes (TB). Even the basic manipulations are far from trivial for data sets of this size. To move the data over the internet, for instance, a special transfer protocol is often set up, as http or ftp connections tend to fail; in some cases, mailing a hard drive turns out to be a faster option. Storing the data on high-performance disks is also costly. The National Institutes of Health (NIH), which funds the vast majority of biomedical research, has been providing an archive to which all data from published papers were to be deposited; however, it is unable to keep up with the terabytes of sequenc-ing data that are being generated per day and has recently announced that it plans to discontinue one of their major databases called Sequencing Read Archive. At a recent gathering of experts to provide guidance to NIH, we estimated that there would be at least 30 petabytes (1 petabyte = 1,000 terabytes = 1,000,000 gigabytes) of sequencing data in the next couple of years.

Analysis of these data presents a multitude of serious challenges. To give an example, a first step in analysis is genome ‘alignment’, in which every short sequences (e.g., TGAGC…GCGTG) is compared to the ‘reference genome’ sequence to identify the location(s) that most closely match the given sequence. This string-match process, with the possibility of gaps of unknown size, can be done blazingly fast for a single sequence by one of several algorithms available. But repeating this process more than 100 billion times, as required in some of our work, requires specialized algorithms and significant computing power, typically hundreds or thousands of compute com-puting nodes. High-performance computing has long been a domain of physical sciences, but biological sciences are proving to be the next frontier in computational research.

One area of interest for my laboratory is a detailed characterization of the cancer genome and what it might tell us about the initiation and progression of the disease. Despite decades of research, there has been little improvement in treatment of many tumors: for the most aggressive form of brain tumor (glioblastoma), for instance, the median survival rate remains essentially the same as it was thirty years ago. Given that most approaches have failed to yield significant progress, the hope is that sequencing the genome of those brain tumor cells will give us some insights, especially in relation to other clinical data of the patients. There is now a major effort by the NIH called The Cancer Genome Atlas, in which 500 patients for each of the 20 tumors chosen are being characterized. This includes profiling of several aspects of the tumor cells such as the activity level of every gene, as well as whole-genome sequencing for an increasingly large fraction of the patients. There is also an international effort called International Cancer Genome Consortium, which involves more than a dozen countries with each profiling a particular tumor type. Through our involvement in these consortium projects, we have learned a great deal about cancer genomics. One of the distinguishing characteristics of the cancer genomes is the presence of structural rear-rangements, e.g., segment of one chromosome being fused with another to produce an altered form of a protein. By developing new strategies for identifying these genomic alterations in the cancer genome, we will be able to better understand the ‘driver’ events that impact tumorigenesis.

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KSEA LETTERS Vol. 40 No. 4 June 2012 9

The era of widespread genome sequencing has begun, although our ability to understand the data is in its infancy. The new mantra in the field now is ‘A $1,000 genome, $1 million analysis’, referring to the fact that while the sequencing of the genome is getting less expensive every year, assembling a team of experts to analyze and interpret the genome is more costly. One thing we do know about the human genome is that it is far more complex than we have imagined, and that a phenotype—e.g., why one gets cancer or diabe-tes—is a complex interaction of genetic and environmental factors that we may not be able to disentangle for years to come. This is well demonstrated by the fact that we still don’t know the precise genetic underpinning for one of the traits that are most clearly genetic in nature—one’s height—after many years of intense research.

The ultimate application of this technology is its use in the clinic: a physician would prescribe sequencing of the patient genome, and information from his genome would be used to guide the treatment of the patient. For patients with family history, sequencing of the genome can be tremendously helpful, as there are already drugs such as Iressa and Gleevec that are effective only for patient with cer-tain mutations in their genome. Healthy individuals could also get their genome sequenced to better understand their predisposition to various diseases, although distinguishing the key disease-related variants from a sea of features will be difficult for the immediate future. For the short term, analysis of a genome will lead to a large number of false positive findings. But, as platforms and algorithms are further developed and more data are accumulated, this high-throughput sequencing technology will have profound impact both in advancing basic sciences and in applications to patient care.

figure 1. (a) Illumina HiSeq 2000 sequencer; a single run of this machine generate nucleotide sequences of ~6 billion short DNA fragments; (b) Genomic alterations in an ovarian cancer patient, identified by whole-genome sequencing analysis. The numbered sections on the outer circle indicate chromosomes, the green and red lines indicate intra- and inter-chromosomal rearrangements that could disrupt the normal function of the impacted genes.

(a) (b)

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technical articles

a qUest for the origin of the Universe[Jaehoon Yu]

Professor, PhysicsUniversity of Texas at Arlington

Whenever we step out to the backyard and look up the sky, we are touched by the beauty of the universe and wonder how the beau-tiful universe works, what make it up, what rules it follow, and ultimately where we all come from. The quest for answers to these fundamental questions begins with looking into the smallest possible distance scales human can probe. One of the most fundamen-tal properties of the fundamental particle is the fact that they cannot be broken into any smaller pieces. The field of particle physics looks for these fundamental building blocks of the universe and seeks to understand the forces between them to better our and our next generations’ lives.

Experimental part of the field uses powerful particle accelerators and massive detectors to accomplish the above goals. The ever-smaller distance scale needed to look deeper into the matter requires ever-higher energy accelerators, and the energetic particles emerging from the interactions of accelerated particles require large detectors. Theories must provide comprehensive models with precise predictions. They have been successful in describing observed phenomena and unifying two of the four known fundamental forces – electromagnetic force and the weak nuclear force – into one. The progress of these theoretical understanding resulted in the

Standard Model (SM) [1] of particle physics which presents a simple but an elegant picture of the fundamental particles and forces.

In SM, all visible matters in the universe consists of six quarks, six leptons (parti-cles with small mass), 12 force carriers (there are 2 W bosons and 8 gluons) and one electrically neutral particle called the Higgs particle that is a manifestation of a mechanism that gives mass to all fundamental particles. Predictions of SM have been successfully confirmed by precision measurements for the past few decades. The model is incomplete, however, in the sense that there still remain numerous outstanding and fundamental questions; such as what is the origin of mass, why is there matter- anti matter asymmetry, what are dark matter and dark energy that make up 96% of the universe and what new physics lie beyond the SM? One of the key missing elements is the Higgs particle whose mass is not predicted in SM, making the search for the particle much more challenging since searches must be done in a wide range of mass and eliminate them. It also is acknowledged that, from the theoretical standpoint, SM must be part of a larger theory (“beyond” the SM or BSM), which is yet to be experimentally confirmed.

In mid March 2010, the new particle accelerator, the Large Hadron Collider (LHC)[2] at the European Organization for Nuclear Research (CERN) [3] in Geneva, Switzerland started colliding protons at the energy of 7 Tera electron Volts (TeV), the highest energy humans ever accomplished. The two large general-purpose particle physics detectors, ATLAS (A Toroi-dal LHC ApparatuS) [4], shown in a photo in Figure 2, and CMS (Compact Muon Solenoid) [5], together with three other experiments started taking data from the collisions. The LHC and the detectors have been operating superbly and have ac-cumulated large amount of data in 2011 and presented results in Higgs searches.

KSEA LETTERS Vol. 40 No. 4 June 201210

figure 1. Fundamental Particle Schedule of the Standard Model

figure 2. A photo of the ATLAS detector LHC

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As the ratio of the measured production probability with respect to the SM pre-dictions Figure 3 shows, the combination of both the experiment shows over a 3.1 standard deviation signature of the Higgs particle at the mass of 126GeV. Any values of the mass below the line at the ratio of 1 have been eliminated, leaving only very little sliver of mass range. The 3.1 standard deviation excess at the mass of 126GeV corresponds to a confidence level of 99.7% for having observed the real Higgs particle. While this confidence level is quite high in everyday standards, it is still insufficient to claim a definitive discovery of the Higgs particle since the canonical significance of a discovery is over 5 standard deviations, the confidence level of 99.99994%.

In 2012, the LHC increased its energy to 8TeV, and the experiments have been taking data since late March. The amount of data expected through 2012 will quadruple the amount of data collected in 2011, increasing statistical significance by a factor of two. This will allow the LHC experiments to either definitively dis-cover the Higgs particle or definitively eliminate the existence of it. The discovery will open a new era of another powerful particle accelerator, the linear electron-positron collider, to investigate the property of the discovered particle precisely while the definitive elimination of the Higgs particle will require a whole new theory of physics to describe the universe and its origin.

As part of understanding the fundamental principle of the universe, many particle physics experiments are looking for incontrovertible evi-dence for new physics while the search for the Higgs particle is under-going. One of the most popular suggestions for the new theory is Su-persymmetry (SUSY) [6] which introduces a new symmetry between fundamental particles. SUSY signals are of particular interest, as they provide a natural explanation for the “dark matter”, known to make up 23% of our universe, and help us to understand the fundamental connection between particle physics and cosmology. An example of a new experiment [7] is an ultra sensitive measurement of a particular particle, called a K-particle or Kaons, at the particle accelerator facility in the US’ Fermi National Accelerator Laboratory (Fermilab)[8] near Chicago. The precision measurement of Kaon’s decay probability to a particular final state (~10-11) with respect to SM prediction measured in the detector shown in Figure 4 can provide a definitive evidence of paradigm changing new fundamental physics.

In a quest for the original of the universe, particle physics uses powerful accelerators and large detectors to capture the most illusive particle thus far and to seek new physics that might yet to be discovered. The year 2012 will likely be the year the Higgs particle is found or is completely eliminated, which would stimulate more vigorous searches for new physics. Korea has been playing a sig-nificant role in this field and will continue to do so in the future, leveraging the resources and infrastructures accumulated through the Rare Isotope Science Project (RISP) [9]. Korea’s participation to an experiment like the ultra precision Kaon measurement above will put Korea at the front line in searching for paradigm changing new physics and become a strong leader and a meaningful partner to the world in a quest for the origin of the universe. references[1] S.L.Glashow and S. Weinberg, Phys. Rev. Lett. 20 (1968) 224-227; A. Salam, Conf. Proc. C680519 (1968) 367-377[2] LHC, The Large Hadron Collider, http://lhc.web.cern.ch/[3] CERN, European Center for Nuclear and Particle Research, Director R. D. Heuer, http://www.cern.ch/ [4] ATLAS Collaboration, Spokesperson F. Gianoti, http://www.atlas.ch/ [5] CMS Collaboration, Spokesperson J. Incandela, http://cms.cern.ch/ [6] D. Volkov and V. Akukov, JTEP Lett. 16 (1972) 438; Phys Lett. 46B (1973) 109[7] ORKA, The Golden Kaon Decay Experiment, FNAL P1021 (2011)[8] Fermi National Accelerator Laboratory, Director Dr. P. Oddone, http://www.fnal.gov/[9] S. Kim, Director, Rare Isotope Science Project, http://www.ibs.re.kr/en/core_project/ion_accelerator/index.jsp

figure 3. Ratio of the measured Higgs pro-duction probability to SM prediction as a function of its mass

figure 4. A schematic diagram of the Kaon detector for a new Kaon experiment at the US’ Fermilab

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technical articles

neUroiMaging to visUalize White Matter fiber connections in the brain[Jongho Lee]

Assistant Professor, RadiologyPerelman School of Medicine, University of Pennsylvania2012 KSEA Young Investigator Grant ($10,000) Recipient

Over the last two decades, neuroimaging has become a powerful tool to study human brain. Various MRI acquisition methods and data processing techniques such as high-resolution structural imaging (basic anatomical information), voxel-based morphometry (structural variation among subjects), functional MRI (task-based brain activity), resting-state fMRI (spontaneous brain activity), diffusion tensor imaging (fiber orientation mapping in white matter) and tracktography (DTI-based fiber connections) have been developed to help us understand how the brain is structured, wired and function. However, the limitations in the achievable resolu-tion which is on the order of sub-mm3 in structural images and several mm3 in fMRI and DTI have become a major challenge. This has led us to pursue new MRI contrast mechanisms and develop higher performance MRI systems. In this article, I summarized my efforts to develop a new method to improve the resolution of fiber orientation maps.

Identifying white matter fiber connections has over a hundred years’ history. Techniques such as gross dissection, myelin staining, double silver staining, Nauta staining, and autoradiography have been developed and provided fiber connection information in histological slices. However, reconstructing 3-dimensional fiber tracts from these data is extremely challenging. The visualization of 3D whole brain white matter connections has become plausible with diffusion tensor imaging (DTI, ref. [1]) which measures relative dif-fusivity of water molecules in fiber bundles using MRI. Unfortunately, this method suffers from a limited resolution and associated partial volume effects. In conventional resolution (8 mm3), more than 1/3 of the voxels have been suggested to have multiple fiber orientations and the orientations in these voxels are thus incorrectly assigned. As a result, the method is limited to identify only large fiber pathways. One way to resolve complex white matter orientation is to achieve in sub-millimeter resolution (~ 0.1 mm) such that the partial volume ef-fects can be reduced. This is challenging in DTI to due to the limited contrast to noise ratio (CNR).

Over the last few years, my colleagues and I have investigated the properties of magnetic susceptibility in the brain at high magnetic field strengths. We have discovered the existence of susceptibility anisotropy in white matter (i.e., white matter magnetic susceptibility

KSEA LETTERS Vol. 40 No. 4 June 201212

figure 1. Various MRI image contrasts: (a) anatomical image using T1 relaxation contrast, (b) func-tional MRI using Blood Oxygenation Level Dependent (BOLD) contrast measuring brain activity, and (c) Diffusion Tensor Imaging (DTI) based on restricted water diffusion in white matter demonstrating fiber orientations

figure 2. Bo orientation dependent R2*: R2* measurement curve from a white matter region shows fiber orientation de-pendent R2* change. This change matches with the anisotropic susceptibility model (blue line)

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KSEA LETTERS Vol. 40 No. 4 June 2012 13

is not a scalar but a tensor that is Bo orientation dependent) [2]. We also have demonstrated that R2* contrast, a magnetic susceptibility sensitive tissue transverse magnetization relaxa-tion rate, is Bo orientation dependent as a function of sin2θ and sin4θ which agrees well with the susceptibility anisotropy mod-el of white matter [3]. Based on this observation, we success-fully developed a novel fiber orientation mapping method from this R2* (R2*-based fiber orientation mapping) [3]. To obtain fiber orientation information, the orientation of white matter fibers needs to be changed relative to the main magnetic field of the MRI. The resulting images from multiple orientations are realigned together and decoded to extract fiber orientation information in each voxel.

One of the major advantages of this new method compared to DTI is SNR efficiency. A similar acquisition scheme to our approach has revealed details of human anatomy in 0.02 mm3 voxels in vivo and 0.0034 mm3 voxels in fixed brains. These resolutions are a few hundred times better than that of DTI and we expect to acquire a similar ultra-high resolution for the R2*-based fiber orientation mapping. Another advantage is that the method directly benefits from high field strength magnets that are currently available (7 Tesla available at UPENN and 11.7 Tesla at NIH) or in-planning (14 Tesla, Neuroscience Research Institute, Gachon university, Korea). The CNR is expected to increase supra-linearly with the field suggesting a factor of 3.5 times increase in CNR at 7 Tesla compared to 3 Tesla. The in-creased CNR can be traded to further increase the resolution. In DTI, however, much limited (or no) improvement at high field is expected due to the corresponding tissue relaxation (T2) decrease at high field.

With these advantages, the new fiber orientation mapping method may provide unprecedented resolution for studying white matter connections. Improved resolution will reveal unidentified white matter fiber tracts that are not visible with conventional DTI (e.g., mammillothalamic tract) and help separate white matter pathways that run closely together (e.g., stria terminalis and fornix). In the clinic, ultra-high resolution tractography may bring new insights into altered connectivity associated with dysplastic cortex, a major cause of focal epilepsy. Additionally, once an ultra-high resolution fiber connection template is available from fixed brain imaging, it will provide abundant a priori knowledge for in-vivo tractography.

In summary, the ultra-high resolution fiber connection map that will be generated by the newly developed R2*-based fiber orienta-tion mapping method will significantly improve our understanding of the brain connections.

references1. Basser, P.J., J. Mattiello, and D. LeBihan, MR diffusion tensor spectroscopy and imaging. Biophys J, 1994. 66(1): p. 259-267.2. Lee, J., et al., Sensitivity of MRI resonance frequency to the orientation of brain tissue microstructure. Proc Natl Acad Sci U S A, 2010. 107(11): p. 5130-5135.3. Lee, J., et al., T2*-based fiber orientation mapping. Neuroimage, 2011. 57(1): p. 225-234.

figure 3. R2*-based fiber orientation map (left) vs. DTI map (right). Blue shows fibers in up-down direction whereas red shows fibers in left-right direction. Both results reveal similar information of fiber orientations

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technical articles

KSEA LETTERS Vol. 40 No. 4 June 201214

ManY-bodY interactions in nanostrUctUres[Cheol-Hwan Park]Research Scientist

The Bosch Research and Technology Center2012 KSEA Young Investigator Grant ($10,000) Recipient

In a hydrogen atom, there is only one electron; by solving the Schrodinger’s equation, we can know everything about the electronic properties of hydrogen. In other atoms, molecules, or in solids, however, there are many electrons. In most practical cases, it is there-fore impossible to describe the interplay of so many electrons or extract useful information from them. Density-functional theory developed in mid 60’s [1,2] is a theory which enabled us to calculate ground-state properties – materials properties related to the elec-tronic ground state such as the equilibrium geometry, bulk modulus, and lattice vibration frequency. The essence of density-functional theory is that all we need to know for ground-state properties calculations is the charge density and not the complex many-electron wave function [1]. In condensed matter physics and materials sciences, density-functional theory is the most commonly used theoreti-cal tool for studying ground-state properties nowadays because of its accuracy and low computational cost.

On the other hand, density-functional theory fails severely in predicting or explaining ex-cited state properties of materi-als, simply because it is a theory only for ground states. How-ever, the subjects of all spectros-copy measurements are excited state properties. For example, the system being investigated is perturbed by injecting an elec-tron [fig. 1(a)] or a hole [fig. 1(b)], or by generating (through an incident photon or by other

means) an electron-hole pair [fig. 1(c)]. After this creation of an elementary excitation, all the other electrons, holes, and ions of the system participate in screening the external perturbation [fig. 1]. Thus, many-body interaction effects are very important in investigat-ing the excited state properties. Although density-functional calculations are normally performed using mean-field interactions (treat-ing other electrons by some mean-field potential), in order to describe excited state properties accurately, quite often, it is necessary to go beyond mean-field level of approxi-mations. I have been investigating the interactions between charge carriers, phonons, plasmons, and other elemen-tary excitations in solids and nanostruc-tures using many-body perturbation theory approaches [4,5], which is ar-guably the most practical and accurate method.

Many-body interaction effects are much more important in nanostructures than in bulk materials because there are not many charge carriers which can screen an external perturbation and also be-cause charge carriers cannot easily avoid each other. figure 2 illustrates that many-body interactions are extremely important in nanostructures.

figure 1. Elementary excitations generated during spectroscopy experiments and the subsequent relaxation, or screening, of the environment. (a) Electron injection. (b) Hole injection. (c) Electron-hole pair creation. (Figure 1 adapted from Ref. [3].)

figure 2. (Left) Yoon-Joong Ro, Yoido. (A photo from ohmynews.) Many people are walking on a wide road and they do not have to worry about interfering with others. (Right) Oi-na-moo bridge in Yeongju, Korea. (A photo from the web site of Munsu Myon in Yeongju Si.) People cannot help interacting with each other when crossing the bridge. Similarly, in nanostructures, charge carriers are interacting strongly among one another because it is not easy for them to avoid each other due to reduced dimensionality along one or more directions.

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KSEA LETTERS Vol. 40 No. 4 June 2012 15

In figure 3, the absorbance spectrum of a bo-ron nitride nanotube obtained by considering electron-hole interactions is compared with that without considering these many-body in-teractions. It is clear that only when the inter-action between electrons and holes is consid-ered, the experimental results can be explained. It is noteworthy that the binding energy of ex-citons – onset energy shift upon turning on the excitonic effects – in boron nitride nanotubes (~2.3 eV) is significantly higher than the exci-ton binding energy in hexagonal boron nitride bulk structure (0.72 eV) [8].

figure 4 shows that the lifetime of charge carri-ers in graphene can be quantitatively explained if their interactions with other charge carriers

(including plasmons) and lattice vibrations (phonons) are properly taken into account. Lifetime of a charge carrier is directly related to its transport properties such as mean free path.

In summary, we have shown that many-body interactions are of crucial importance in understanding spectro-scopic properties of nanostructures. First-principles approaches based on density-functional theory and many-body perturbation theory can be suc-cessfully applied in investigating ther-mal and electrical conductivities, and optical and excitonic properties without using empirical parameters obtained from experimental results. Researches in this direction, therefore, have a broad implication in finding new sources of energy such as thermoelectric materials and solar cells.

references[1] P. Hohenberg and W. Kohn, “Inhomogeneous electron gas”, Phys. Rev. 136, B864 (1964).[2] W. Kohn and L. J. Sham, “Self-consistent equations including exchange and correlation effects”, Phys. Rev. 140, A1133 (1965).[3] C.-H. Park, “Excited state properties from many-body perturbation theory”, AKPA Newslett. 29, 7 (2011).[4] M. S. Hybertsen and S. G. Louie, “Electron correlations in semiconductors and insulators: Band gaps and quasiparticle energies”, Phys. Rev. B 34, 5390 (1986).[5] M. Rohlfing and S. G. Louie, “Electron-hole excitation and optical spectra from first principles”, Phys. Rev. B 62, 4927 (2000).[6] M. L. Cohen, “Looking back and ahead at condensed matter physics”, Phys. Today 59, 48 (2006).[7] C.-H. Park, C. D. Spataru and S. G. Louie, “Excitons and many-electron effects in the optical response of single-walled boron ni- tride nanotubes”, Phys. Rev. Lett. 96, 126105 (2006).[8] B. Arnaud et al., “Huge excitonic effects in layered hexagonal boron nitride”, Phys. Rev. Lett. 96, 026402 (2006).

figure 3. (Left) Schematic of a single-walled boron nitride nanotube. (Figure from Ref. [6]) (Right) Absorption spectra of the (8,0) single-walled boron nitride nanotube. The red and green curves are results calculated with and without considering electron-hole interactions (excitonic effects), respectively. This figure is adapted from Ref. [7].

figure 4. (Left) Structure of graphene (from Wikipedia). (Right) Energy broadening (or inverse lifetime) of charge carriers in doped graphene versus electron energy. Black and red curves are the experimental [9] and theoretical results [10], respectively. (Figure adapted from Ref. [10].) Features arising from electron-plasmon interactions and electron-phonon interactions are denoted by arrows.

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Ksea ventUre challenge

rf test labs sUMMarY[Gene Cho]

New York UniversityWinner of the KSEA Business Venture Challenge at YGTLC 2012 ($10,000)

RF Test Labs is focused on developing and implementing innova-tive radio frequency (RF) emissions testing solutions. RF Test Labs employs novel, patent pending magnetic resonance (MR) technol-ogy developed at New York University (NYU) enabling state of the art testing of RF emitting devices such as cell phones, laptops, tab-lets, etc.

Thousands of wireless devices are brought to market annually. In-creased concerns about their RF-emissions safety have resulted in over $1 billion yearly expenditures on mandatory safety testing. Compared to existing procedures, RF Test Labs developed a faster, cheaper, and more versatile technology to provide RF-emissions testing services for device manufacturers.

Relying on the ability to utilize MRI technology for testing of RF emissions, RF Test Labs created a framework called the Magnetic Resonance RF Emissions Test (MR-RFET). MR-RFET is a novel alternative to existing SAR testing methods. This method is advan-tageous for quantifying RF emissions, as it is up to 20 times faster, cheaper, and can scan complex anatomical structures in higher 3D resolution. These advantages help reduce the lead-time associated

with device testing, thereby avoiding a testing bottleneck in the R&D process. Additionally, the method measures minute tempera-ture changes produced by RF emitting devices. This provides a more direct measure of health risks since temperature change is di-rectly correlated with tissue damage.

Speed, cost-efficiency, and versatilty are the differentiators that provide RF Test Labs with strategic advantage over competitors.

(1) Speed : Current SAR testing methods require on average 20 to 40 days to test a single smart phone. RF Test Labs’ proprietary technology can accelerate testing ~20 times, reducing the test duration to 1-3 days. Speed of testing is important for accelerat- ing product development cycles, lowering production costs for the electronic manufacturers.(2) Cost-efficiency : As the MR-RFET method is significantly faster, RF Test Labs’ operational costs are ~4 times lower compared to current testing methods. Pricing for this service will be 20% less than current SAR test pricing. (3) Versatility : MR-RFET enables scanning of complex anatomical structures in higher 3D resolution (sub-millimeter vs. mil- limeter). Since the MR-RFET method estimates temperature changes it is also a more relevant measure of human health risks.

RF Test Labs’ goal is to obtain an 8% share of the market within 5 years of operation, which equates to $110.6M in revenues. The RF Test Labs’ founding team consists of three Ph.D. candidates and a post doctoral fellow experienced in MR research and work-ing at NYU’s Center for Biomedical Imaging. In the picture are Cem Murat Deniz, Daniel Bain, Leeor Alon, Gene Cho, and Iliyana Atanasova (L -> R).

16 KSEA LETTERS Vol. 40 No. 4 June 2012

RF Test Labs, Inc. conducts novel, efficient RF emissions testing using MR-RFET

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creativity, innovation, and integration

Chair: Hyungmin Michael Chung, KSEA Co-Chair: Sang-Dai Park, KOFST

Message froM conrference chair

We invite you to participate in the “US-Korea Conference on Science, Technology and Entrepreneurship (UKC). UKC is the annual flagship conference for researchers, scientists, engineers, and technology experts in academia and industry as well as decision makers and opinion leaders in government, legislative offices, and industry. This year, the conference will be held next to Disneyland near Los Angeles, California in mid-August.

The 2012 conference focuses on interdisciplinary research and development, which draws on the ongoing interactions of sciences, technologies, and engineering, among others. Such convergence and integration accompany creative approaches, innovation, and greater value propositions as well as new issues. The conference also provides competitive opportunities to present scientific and technological advances in various disciplines. In addition, the conference addresses strategic and governance challenges in managing research and development.

We would especially like you to share ideas and perspectives that span generations and professional areas and get to know one another better. At UKC 2012, we emphasize closer interaction between industry and academia. We encourage participants to communicate, collaborate, discover and excel throughout the conference period and afterwards.

Finally, we thank the committee members, session organizers, volunteers and sponsors for their dedication, professional work, sup-port, and generosity.

Please join us this summer in the sunny west coast.

conference theMe

The conference aims at interdisciplinary research and development, which draws on the ongoing interactions of biosciences, informa-tion technologies, and engineering, among others. Such convergence and integration will accompany creative approaches, innovation, and greater value propositions as well as new issues. As new research models emerge, we should share different ideas and perspectives in science and technology. The conference will provide opportunities for communication and collaboration among different disci-plines, generations, industry sectors, and policy makers. The conference will also address strategic and governance challenges in an interdisciplinary environment. We invite academia, research institutions, industry, government and legislative bodies of both countries and vicinities to make the conference an unprecedented transformative event.

KSEA LETTERS Vol. 40 No. 4 June 2012 17

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conference schedUle

interdisciplinary sessions: Biomedical Sciences and Biotechnolgoes, Information Technologies and Applications, Energy & Environ-ment, New Materials and Applications technical tracks: Biology, Biomedical Engineering, Medical Sciences [BIO]/ Advanced Materials and Nanotechnology [MAT]/ Food, Agriculture, Pharmaceuticals [FAP]/ Electrical, Communications, and Computer Engineering [ECE]/ Computer Science, Informa-tion Systems, Industrial Engineering, Management Science [CSI]/ Energy and Environment [ENE]/ Chemical Engineering, Petro-leum, Nuclear [CHE]/ Physics, Astronomy, Chemistry, Math, Stat and other Basic Sciences [BAS]/ Civil, Transportation, Architecture [CTA]/ Mechanical Engineering, Aerospace Engineering, and Ocean System Engineering [MAO]forums and Workshops: Research Funding, Cutting Edge Research and Development, National Research Inititatives, Industry Ex-change, Technology Strategy and Policy, Intellectual Property, Young Generation, Women Scientists and Engineers

indUstrY toUrs

1) Renewable Energy Projects

geotherMal plantsThis project consists of 10 generating plants in the Salton Sea Known Geothermal Resource Area in Southern California’s Imperial Valley. The plants produce electricity solely from naturally occurring geothermal steam. The combined capacity at Imperial Valley is approximately 327 net megawatts.

coachella valleY WindMill farMThis wind farm contains more than 4000 separate windmills and provides enough electricity to power Palm Springs and the entire Coachella Valley. It is a large valley landform in Southern California that extends for approximately 45 miles in Riverside County southeast from the San Bernardino Moun-tains to the saltwater Salton Sea, the largest lake in California. At the San Gorgonio Pass Wind Farm, hundreds of huge wind turbines spread across the desert and hills on either side of the highway greet visitors as they approach the crest of the pass and have become somewhat of a symbol of the area.

noble energY solar pv plantNoble Energy Completes New 300kW Solar Project for Xavier Prep-school, which is one of the largest private installation fields, built in the Coachella Valley to date. The 300kW system will supply enough electricity to more than cover the school’s daytime power demands, saving the institution thousands of dollars in electricity bills each year.

KSEA LETTERS Vol. 40 No. 4 June 201218

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2) Rhythm &Hues Studios

Rhythm & Hues Studios is a visual effects studio serving the major film studios, the headquarters of which are located on the Westside of Los Angeles in the City of El Segundo. With some of the world’s top creative talents and best technologies, Rhythm & Hues delivers outstanding, award-winning visual effects and animation. Dur-ing the tour, you can meet digital artists, come by their studios, and find out how the digital effects and anima-tions are made.

Features include two state-of-the art screening rooms equipped with Christie 2K digital projectors (one with stereoscopic 3D capability), a 4000 sq. ft. machine room, numerous editorial and video conference rooms, as well as a cafeteria and other amenities. Recognized as one of the top facilities of its kind in the world, Rhythm & Hues has contributed to more than 150 feature films.

3) Jet Propulsion Laboratory

The Jet Propulsion Laboratory is a NASA Center in Pasadena, California, managing robotic spacecraft in the exploration of Earth, the solar system and the universe. The laboratory develops satellites, rockets, and other space technologies. About twice the size of California’s Disneyland, the Jet Propulsion Laboratory is a 177-building campus situated in the foothills of the San Gabriel Mountains. In addition to a mission control center and 9,600 square-foot clean room, the lab is home to a simulated Mars landscape called the Mars Yard, as well as a 25-foot space simulator. In the fall of 2009, JPL unveiled its newest building, the environmentally friendly Flight Projects Center, which houses missions during their design and development phases. The tour offers a chance to see satellites, space memorabilia, satellite dishes, and rovers.

4) Orange County Water District

The Groundwater Replenishment System (GWRS) operated by Orange County Water District is the World’s Largest Wastewater Purification System for Indirect Potable Reuse.

Operational since January 2008, this state-of-the-art water purification project can produce up to 70 million gallons (265,000 cubic meters) of high-quality water every day. This is enough water to meet the needs of nearly 600,000 residents in north and central Orange County, California.

KeYnote speaKers

faMilY and entertainMent prograM

Jay Chung, Ph.D.Tayco Engineering, Inc.

Lawrence A. Tabak, D.D.S., Ph.D.National Institutes of Health

Jerry Tessendorf, Ph.D.Rhythm & Hues Studio, Clemson Univ.

Universal studio disney landgetty Museum

19KSEA LETTERS Vol. 40 No. 4 June 2012

Ronald M. Evans, Ph.D.Salk Institute

queen Mary hollywood bowl

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global Joint research proJect in indUstrial original field

Korea Evaluation Institute of Industrial Technology (KEIT) and KSEA have been working together to increase the participation of Korean-American scientists and engineers for KEIT global joint research projects. KSEA performed a joint research demand survey for “A new project for 2012 Industry Fusion Original Technology Development Business” that facilitated the joint R&D projects between Korean-American scientists and engineers and Korean companies, sponsored by KEIT. Since the 1st announcement in January, 2012, 110 survey forms in the fields of information communication and new innovative industry areas were received from 74 Korean Americans. The total survey participants were categorized as the university researchers with 77 surveys and industry researchers with 25. After the extensive and objective peer review process, five proposals were selected, and, currently, the contract agreement process between KEIT and fiving winning teams with participants from USA are under way.

Among the five finalists, three of them were KSEA members: Dr. Dong Sam Ha, Dr. Jaehwan John Lee and Dr. Gang-Ryung Uh. Dr. Jaehwan John Lee is Associate Professor of Electrical and Computer Engineering at Indiana University-Purdue University In-dianapolis. His proposed research project was titled, “Software development for the big database analysis and management based on the next generation memory technology”, and will be undertaken jointly with Dr. Sung Jin Huh of ETRI. Dr. Gang-Ryung Uh is Associate Professor of Computer Science Department at Boise State University and He will conduct a research project titled, “Sensor terminal supporting software and applied service development based on smart device to provide a personalized service,” jointly with Dr. Doohwan Shin at Moneual, a home media system company in Korea.

Particularly, Dr. Ha, Professor of Department Electrical and Computer Engineering at Virginia Tech University, has served as pro-gram chair of 2011 UKC in Seattle and the President of Southern Virginia Chapter of KSEA. The proposed project was to develop a combined switching system technology for the Next Generation Optical Transport Network. The principal investigator of the joint project Dr. Jong Hyun Lee of Electronics and Telecommunications Research Institutes (ETRI) where Prof. Ha is to participate in developing 400G Optical Transceiver. The market size for the combined switching and transmission equipment is expected to grow to 50-billion dollars in 2020, and the proposed project will generate significant economic effects. Recently, Dr. Ha wrote to President Hosin Lee, “Yes, I have received a research project from ETRI through KETI. I greatly appreciate KSEA for providing such an op-portunity. Another reason to buy beer to you!”

KSEA is under a contract agreement with KEIT in devel-oping research problem statements to be considered by KEIT for the next fiscal year. The project team includes Prof. Hosin Lee of University of Iowa, Prof. Yongho Sohn of Central Florida Univesity, Prof. Hanseup Kim of Uni-versity of Utah, Dr. Kyungjae Myung of NHI, Hyunggun Kim of University of Texas Medical School at Houston, Benjamin Lee of INVIA Medical Imaging Solutions, and Office Manager Euna Yoon of KSEA. KSEA members submitted over 70 problem statements to KEIT that will be considered by KEIT staff when they are to develop the request for proposals next year. As a token of apprecia-tion, $50 will be provided to each of all KSEA members who submitted problem statements. By suggesting emerg-ing research topics at the very early stage of developing requests for proposals, if the suggested topic is selected, everyone will be invited to submit the proposals includ-ing ones who provided the seeds for developing requests for proposals in the process. Recently, President Hosin Lee visited KEIT to discuss about the progress in identifying industry research topics to be considered next year and future collaborations between KSEA and KEIT. A cooperative relationship between KSEA and KEIT was initiated during the 40th term and the outcome is mutually beneficial to both KSEA members and KEIT staff. Therefore, this win-win relationship is expected to grow in the future.

special proJect

KSEA LETTERS Vol. 40 No. 4 June 201220

President Hosin Lee visited KEIT in Korea for a MeetingEun Young Ko, Hosin Lee, Chang Hwa Woo, and Sang Il Lee (L -> R)

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21KSEA LETTERS Vol. 40 No. 4 June 2012

Ksea-snU MoU cereMonY

president lee participates at the start-Up festival & signs an MoU With snU

On May 30, 2012, the national Start-up Festival was held on campus of Seoul National University (SNU) where over 1500 students from 70 universities participated. The main purpose of the national Start-up Festival was to create a national network of students who are interested in getting an education on how to start a new venture company. As part of the national Start-up Festival, Presi-dent Hosin Lee was invited to give a presentation to professors and staff from over 70 universities about the start-up college educa-tion programs in USA. During his presentation, he introduced the KSEA and the KSEA business venture challenge held during YGTLC 2012 in San Francisco. He also played the YGTLC 2012 video to all participants. Three winners from the KSEA business challenge were also invited to give presentations to all participants. Minister Ju-Ho (check the spelling) Lee of MEST and President Lee also attended the outdoor event of matching students with mentors in the afternoon. The start-up festival was a great success.

On June 1, a Memorandum Of Understanding (MOU) was established between KSEA and SNU R&DB Foundation towards devel-oping strategic cooperative relationship in the field of science and technology. SNU R&DB Foundation was established in 2008 to manage research fund and intellectual property of University and have mainly focused on performing government-aided research and joint research contracts with industries.

The signing ceremony took place at the SNU R&DB Foundation office on campus of Seoul National University. Prof. Hosin Lee, President of KSEA, and Prof. Jun-shik Lee, Director of SNU R&DB Foundation signed the MOU document taking the first step on the path towards the mutual cooperation in the future. With this agreement, both parties will cooperate on a mutually beneficial and complementary basis in planning and implementing joint projects and joint workshops in the field of science and technology. This MOU is the tenth one that was signed during the 40th term and, like the one signed between KSEA and KEIT on July 1, 2011, it is expected that all of them would lead to more collaborative projects and workshops in the future.

From left -> Right: Ji-young Park, patent agent of SNU R&DB, Kook-sun Hong, President of SNU Holdings, Jun-shik Lee, Director of SNU R&DB Foundation, Hosin Lee, President of KSEA, Doo-Kyoo Kim, patent agent of SNU R&DB, Dong-hyun Baek, director of SNU Holdings.

President Hosin Lee is giving a presentation at the na-tional Start-up Festival.

President Hosin Lee (left) and Juho Lee of MEST (right)

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KSEA LETTERS Vol. 40 No. 4 June 201222

nMsc 2012 report

nMsc 2012 SUMMARY REPORT

One of KSEA visions is to promote and cultivate the next generation of scientists and engineers and the National Mathematics & Science Competitions (NMSC) help KSEA achieves this goal and serve the science community in the US. On April 21, 2012, 4th - 11th grade students participated in the KSEA NMSC 2012, which marks the 11th for mathematics and the 7th for science competi-tion. NMSC is co-sponsored by KSEA and the Korea-U.S. Science Cooperation Center (KUSCO) and is executed by KSEA chapters and branches. This year, we had a new record participants of 2312 students.

KSEA started a Pilot High School Physics Contest (HSPC) this year. The objective of Physics Contest is to promote interest in phys-ics as a fundamental science. It was open to all high school students in grades 9 through 12 in North Carolina (Raleigh) and North Texas chapters as a pilot program before expanding to national level. The level of problems was set to High school physics (Algebra based). 14 students participated in the competition this year.

Out of 2312 participants for the Math Competition, KSEA recognized three top-scoring students from each grade, 4th through 11th, as national winners. These students represent states of Virginia, Washington, Texas, Georgia, North Carolina, California, Illinois, Ohio, and New Jersey. Each national winner was awarded with a certificate and a check of $500, $400, $350 for the 1st, 2nd, and 3rd places, respectively. The winners are summarized in the table below:

name grade school chapter rank

Seo, Dong-yun 4 Willow Springs Elementary School Washington Metro First

Kwon, Yoonseo 4 Findley Oaks Elementary School Georgia Second

Han, Justin 4 Louise Archer Elementary School Washington Metro Second

Yoo, Seungmin 5 Mary Scroggs North Carolina First

Kwon, Sunghyun 5 Del Mar Hills Academy San Diego Second

Im, Shawn 5 Parsons Elementary School Georgia Third

Kwon, Minjee 6 Smith Middle School North Carolina First

Platt, Alex 6 Avery Coonley School Chicagoland Second

Chung, Richard 6 Lakota Middle School Seattle WA Second

Choi, Tomas 7 William Hopkins Junior High Silicon Valley First

Shin, Claudia 7 Chinook Middle School Seattle WA Second

Choi, Jaeyoung 7 St. Mark’s School of Texas North TX Third

Park, Yoobin 8 Rocky Run Middle School Washington Metro First

Lee, Sion 8 Longfellow Middle School Washington Metro Second

Kim, Samuel 8 Longfellow Middle School Washington Metro Third

Tian, Peter 9 Columbus Academy Dayton-OH First

Jeong, Jin Oh (John) 9 Northern Valley Demarest High School New Jersey Second

Kim, Ildoo 9 Thomas Jefferson High School Washington Metro Third

Park, Edward 10 Walton High School Georgia First

Park, Minho 10 Leland High School Silicon Valley Second

Kwon, Soonho Steven 10 Bergen County Academies New Jersey Third

Choi, Donghyun 11 Mission San Jose High School Silicon Valley First

Oh, Jung Hyun 11 New Trier High School Chicagoland Second

Park, Jongwhan 11 Bergen County Academies New Jersey Third

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KSEA LETTERS Vol. 40 No. 4 June 2012 23

nMsc 2012 SUMMARY REPORT

National winners and their families were invited to attend the award ceremony, where they were recognized of their achievements with an award certificate and a check.

WASHINGTON, D.C. MAY 12, 2012

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scholarship 2012 SUMMARY REPORT

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2012 Ksea scholarships

KSEA Scholarship Committee is pleased to announce the recipients of 2012 KSEA Undergraduate and Graduate Scholarships. Evalu-ation criteria were academic performance (30%), Recommendation (20%), KSEA activities and community service (30%), and Essay (20%), which asked for 1,000 words on “Ethical Perspective and Attitudes toward the Society” and “The Roles of Scientists and Engi-neers for Modern World”, for Undergraduate and Graduate scholarships, respectively.

We received total of 54 applications this year for undergraduate scholarships, among which 41 were complete for evaluation. For graduate scholarships, we received total of 58 applications, among wich 47 were complete. The committee carefully reviewed all the complete applications and selected the recipients as seen in the table below. Scholarship recipients were announced online on May 1, 2012, and notified individually, and they are entitled to receive an award certificate and $500, $1,000, and $1,500 for for essay scholar-ships, undergraduate and graduate scholarships, respectively.

Undergraduate graduate

name school scholarship name school

Hongwoo Jang Univ. of Illinois at Urbana-Champaign Jae S. and Kyuho Lim Seung Hyun Kim Univ. of Pennsylvania

Yena Son University of Virginia Yohan & Rumie Cho Ji Eun Han Univ. of North Carolina

Michelle Lee Wellesley College Chunghi Hong Park Won Chan Oh Univ. of California, Davis

Ga Young Moon New York University Chunghi Hong Park Youn Na Johns Hopkins University

Suhyoung Lee Northwestern University SeAh-Haiam Youngjib Ham Virginia Tech

Chulwoo Park The University of Utah Yoon Soo Park Sinchul Yeom California Inst. of Technology

Ka-Hyun Paek Virginia Tech Woojin Juhee Bae North Carolina State University

Won-Jun Kuk Williams College Hyndai Youngsoo Seol Iowa State University

Stephanie Jeong Pennsylvania State University Shoon Kyung Kim Hyunwook Park University of Virginia

Min Lee Harvard University Inyong Ham Chul Sung Texas A&M University

Amber Kim Rutgers University Nam Sook & Je Hyun Kim Jin Yong Oh University of California, Davis

Youngwan Kim University of Texas at Dallas Wan-Kyoo Cho Peter Kim Yale University

MeeAe Hong University of Washington Changkiu Riew & Hyunsoo Kim Hyun-Woo Kim Pennsylvania State University

Maroo Ghil University of Georgia Essay Jun Suk Rho Univ. of California, Berkeley

Steve Han University of the Pacific Essay Kangmu Lee Univ. of California, San Diego

Joon Sohn The University of Texas at Dallas

Samuel Roh Duke University

Young Eun Ju Duke University

Yun Jae Jo University of Virginia

Henry Shin Northwestern University

Joshua Cho North Carolina State University

Alex Chung University of Texas at Dallas

Michael Lee University of Washington

Kyungmin Chae University of Virginia

YeBin Kim University of Virginia

Sumin Park Haverford College

Scott Kim Belmont University

Susie Lee Georgia Institute of Technology

David Ji North Carolina State University

Ye Ji Shin University of California, Los Angeles

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celebrating nMsc 2012 national Winners & recipients of Ksea UndergradUate scholarships and YoUng investigator grants

KSEA Award Ceremony was held on May 12, 2012 at Tysons Corner Marriot Hotel, Vienna, VA, to acknowledge the achievements of KUSCO-KSEA NMSC national winners, KSEA Undergraduate Scholarship winners and KSEA Young Investigator Grant (YIG) winners. The event was honored by the attendance of 10 NMSC winners, 12 Undergraduate Scholarship winners, and YIG winner Dr. Dr. Cheol-Hwan Park from Robert Bosch Research and Technology Center. Many students traveled to the event from all over the US with their family members who also attended the event with great pride.

After a brief introduction of KSEA by President Hosin David Lee, KSEA Advisor, Prof. John Kim (Member of NAE) and Mr. Inil Lee, Korean Embassy Science Counselor gave motivating, yet philanthropic congratulatory remarks to the students and parents. Maryland State Delegate, Ms. Susan Lee and Maryland Higher Education Commissioner, Mr. Chung K. Pak also gave congratula-tory remarks that emphasized the importance of activities like NMSC and KSEA scholarships to the socio-economic welfare of our society. Keynote speaker, KSEA Advisor, and a member of PCAST, Dr. S. James Gates, Jr. emphasized the value of Korean herit-age to the young students, and the vital role of science, technology, engineering and mathematics (STEM) to the audience. Prior to luncheon, Dr. Kyung Mi Choi, the chair of 2012 NMSC committee provided the details of work that went into “making” of the examinations. During luncheon, President Lee entertained the audience with videos from UKC 2011, YGTLC 2012 and 40 Years of KSEA, and charged the young students in the audience for the challenging and fun road ahead – while recruiting them as future members of KSEA.

After luncheon, President of KUSCO, Mr. Seung Jong Lee gave a congratulatory remark, further forging KUSCO’s commitment and support for KUSCO-KSEA events such as NMSC. Then, each student in attendance was given the National Award Certificate for KUSCO-KSEA NMSC and KSEA Undergraduate Scholarship. Then Dr. Dr. Cheol-Hwan Park was acknowledged as one of the YIG winners. The event was capped with introduction of 41st President, Dr. Hyungmin Michael Chung who announced the details of UKC 2012 and KSEA’s commitment for student development.

KSEA LETTERS Vol. 40 No. 4 June 2012 25

aWard cereMonY in Washington, d.c

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events NATIONAL MATHEMATICS AND SCIENCE COMPETITION

KSEA LETTERS Vol. 40 No. 4 June 201226

South Texas ChapterAfter the Competition

North Carolina ChapterMathematics Examination

Southern California ChapterRocket Launch

Sacramento ChapterTower Building

Philadelphia ChapterAirplane Design

North Texas ChapterHigh School Physics Contest

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events CHAPTERS, APS, REGIONAL CONFERENCES

Korea ChapterRevival Meeting (June 2, 2012)

KSEA LETTERS Vol. 40 No. 4 June 2012 27

New York Metro and New Jersey Chapters, KASBP and YG Northeastern Regional Conference (June 15 - June 16, 2012)

Iowa City ChapterKSEA President Cup Tennis Tournament & Picnic

(June 2, 2012)

Central Texas Regional ConferenceAustin, TX (May 19-20, 2012)

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coRpoRATE SponSoRS of KSEA

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directors committee (40th administration) president: hosin “david” lee, Univ. of Iowa 319-335-6818, [email protected]: hyung-Min Michael chung, Calif. State Univ. 562-985-7691, [email protected] president: Kookjoon ahn, DOT 916-227-9257, [email protected] president: hee-Koo Moon, Solar Turbines 619-544-5226, [email protected] director: Yongho sohn, Univ. of Central Florida 407-882-1181, [email protected] director: seri park, Villanova University 610-519-3307, [email protected] director: benjamin lee, INVIA Medical Imaging Solutions 734-678-1285, [email protected] group director: eun-suk seo, Univ. of Maryland 301-405-4855, [email protected] director: sung Yi, Portland State Univ., [email protected] operations director: Kyungjae Myung, NIH 301-451-8748, [email protected] director: Youngsoo park, Argonne National Lab 630-252-5094, [email protected] director: hanseup Kim, Univ. of Utah 801-587-9497, [email protected] director: Jungah Jung, Millennium Pharmaceuticals 973-752-5245, [email protected] director: byungdo Kim, Univ. of Texas at Austin [email protected] director: israel (sun Min) Jung, The Boeing Company 425-263-2233, [email protected] director: byungkyu brian park, Univ. of VA 434-924-6347, [email protected] director: hyunggun Kim, Univ. of Texas HSC at Houston, 713-486-2342, [email protected] director: Jaehoon Yu, Univ. of Texas at Arlington 817-272-2814, [email protected]

headquarters staffit Manager: seung seok choi, 703-748-1221, [email protected] Manager: Kelly han, 703-748-1221,[email protected] Manager: euna Yoon, 703-748-1221, [email protected] administrator: Yoon hee chang, 703-748-1221, [email protected]

auditorsgye Won han, 858-784-7189, [email protected] ryu, 832-377-7267, [email protected] Jong lee, 212-650-7260, [email protected]

elected councilorsgroup a: physicseun-suk seo, 301-405-4855, [email protected] b: chemistryseogjoo Jang, 718-997-4110, [email protected] c: Mathematics, geology, Meteorology, statistics, othersYonil park, 301-402-1438, [email protected] d: biology, botany, zoology, biomedical engineering, genetic engineeringJung hyeob roh, 713-500-6756, [email protected]

Korean-american scientists and engineers association1952 Gallows Road, Suite 300, Vienna, VA 22182Tel: 703-748-1221. Fax: 703-748-1331 Email: [email protected]. Web: http://www.ksea.org

chul hee Kang, 509-335-1409, [email protected] e: agriculture, ecology, food, nutritionhaejung an, 949-608-4408, [email protected] f: Medical science, pharmaceutical science, veterinary Medicine, physical educationKyoung-Jin Yoon, 515-294-1083, [email protected] g: chemical engineering, textile engineering, nuclear engineering, petroleum engineering, applied chemistryinchan Kwon, 434-243-1822, [email protected] h: Mechanical engineering, aerospace engineering, naval architectureMun Y. choi, 860-230-7003, [email protected] han, 301-405-5255, [email protected] i: Materials science, Metallurgy, Mining engineeringKyeong-ook lee, 630-252-9403, [email protected] J: civil engineering, architecture, environmental engineeringJun-seok oh, 269-276-3216, [email protected] (richard) Kim, 919-515-7758, [email protected] K: electrical & electronics engineering, communication engineering Ki Wook Kim, 919-515-5229, [email protected] Jin Kwon, 732-758-3242, [email protected] l: computer science, systems engineeringKyung dong ryu, 914-945-2502, [email protected] doh, 781-565-5229, [email protected] M: industrial engineering and Mgmt sciencesunghoon Kim, 201-988-9094, [email protected]

former president councilorsJae hoon Kim, The Boeing Company, 425-786-7723, [email protected] chin ok lee, Rockefeller University, 212-327-8617, [email protected] Wayne lee, Univ. of Rhode Island, 401-874-2695, [email protected]

chapter presidentscentral penn (1) Jungwoo ryoo, 814-949-5243, [email protected] (3) chulsung Kim, 678-407-5776, [email protected] (4) chan Kyoo choi, [email protected] (6) hahnsang Kim, 734-223-7284, [email protected] (7) duck Young chung, 630-252-4907, [email protected] (8) Yunje oh, 952-835-6366, [email protected] england (9) sangun lee, 508-887-4564, [email protected] new Jersey (10) hong-Yong Kim, [email protected] Metro (11) Jun ho shin, 718-631-6255, [email protected] edun. carolina (12) sung Woo Kim, 919-513-1494, [email protected] (14) bomjun Kwon, 614-366-8377, [email protected] Wa (15) Wookuen shin, [email protected] (16) Jin s. Kang, [email protected]. louis (17) Jayoung choi, 310-562-7917, [email protected] southern ca (18) chan seung park, 951-781-5771, [email protected] texas (19) sukjoo choi, 281-249-8732, [email protected]. Metro (21) June M Kwak, 301-405-9726, [email protected] (23) dong Joo daniel Kim, 334-844-4864, [email protected] tx (24) Jinwoo lee, 512-785-2098, [email protected] valley (30) Jun Young huh, [email protected] (31) Mihyun bae, 443-804-7507, [email protected] (32) Thak sang byun, [email protected]. texas (40) Jiyoung Kim, 972-883-6412, [email protected] va (41) Jungwook Jun, [email protected]

KSEA LETTERS Vol. 40 No. 4 June 2012 53

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central il (42) seung-Yul Yun, 217-255-8540, [email protected] va (49) dong s. ha, 540-552-1965, [email protected] city (52) Yang oh Jin, [email protected] (56) You han bae, 801-474-1945, [email protected] (58) Young lee, 916-227-7645, [email protected] diego (60) Yongkyoon in, 858-455-6655, [email protected] (62) sung Yi, [email protected] dakota (65) chiwon W. lee, 701-361-9411, [email protected] fl (67) hyoungjin cho, 407-927-4301, [email protected] bay (68) Myung Kim, [email protected] (903) duk-hyung lee, 859-858-3511, [email protected] Korea (905) tammy cho, 82-18-282-7995, [email protected]

committee chairscontest committee: Kookjoon ahn, 916-227-8357, [email protected] committee:James song, 301-602-2206, [email protected] Management committee:Kang-Wook lee, 914-945-3070, [email protected] committee:Yong nak lee, 847-577-5967, [email protected] and awards committee:sung Kwon Kang, 914-945-3932, [email protected] planning committee:saeyoung ahn, 301-646-6602, [email protected] committee:Jae hoon Kim, 425-786-7723, [email protected] committee:nak ho sung, 617-627-3447, [email protected] committee:seong gon Kong, 215-204-7932, [email protected] Young generation committee:John hyung lee, 310-280-8269, [email protected] chapter presidents committee: Wookeun shin, 206-714-4110, [email protected]

affiliated professional society (aps) presidents association of Korean neuroscientists (aKn)Jin Mo chung, University of Texas, [email protected] of Korean physicists in america (aKpa)eun-suk seo, University of Maryland, [email protected] life scientists association (blsa)Woochang hwang, Johns Hopkins University, [email protected] american construction, engineering, and project Management association (KacepMa)Young hoon Kwak, George Washington University, [email protected] food technologists association (Kafta)Youngmo Yoon, Sensient Flavors LLC, [email protected] intellectual property lawyers association (Kaipla)Joo Mee Kim, Rothwell, Figg, Ernst & Manbeck, P.C., [email protected] Materials society (KaMs)Jiyoung Kim, University of Texas at Dallas, [email protected] Mathematical scientists association (KaMsa)hae soo oh, University of North Carolina at Charlotte, [email protected] society for biomedical informatics (Kasbi)James s. song, National Center for Biotechnology InformationNational Institutes of Health, [email protected] american society for biotech & phamaceuticals (Kasbp)Yong-hae han, Bristol-Myers Squibb, [email protected] energy exploration & production society (Keps)sam Jae cho, Ryder Scott Company, [email protected] computer scientists & engineers association in america (Kocsea)Yoohwan Kim, University of Nevada, Las Vegas, [email protected] offshore engineers association (Koea)Yong lae shim, ABS Technology, [email protected]

Korean life scientists at Ucsf (Kolis)dae hwi park, University of California- San Francisco, [email protected] pathologists association of north america (Kopana)eun Young lee, University of Kentucky , [email protected] transportation association in america (Kotaa)alex hak-chul shin, Louisiana State University, [email protected] society of civil and environmental engineers (Kscee)Myong ho steve ro, Lee & Ro, Inc., [email protected] Women in science and engineering (KWise)sanghee Yoo, Vertex Pharmaceuticals, [email protected] scientists association (nih-Ksa)Jung hyung park , National Institutes of Health, [email protected] York Korean biologists (nYKb)sae Woong park, Weill Cornell, [email protected] triangle park bioscience and biotechnology Meeting (rtp b&b)hangsik Moon, Syngenta Biotechnology, Inc., [email protected] diego Korean biomedical association (sdKoba)Jongdae lee, UCSD, [email protected] society of Korean statisticians in america (sKsa)sin-ho Jung, Duke University, [email protected]

ex-presidentsKiuck lee, Marquette Univ., 312-787-7060, [email protected] bae Kim, USC, 213-740-2311sang il choi, POSTECH, 919-357-7018, [email protected] bang Woo, Yonsei Univ., 82-2-2123-3555, [email protected] nak lee, HTRD, 847-577-5967,[email protected] Young park, NC State Univ., 919-848-6110, [email protected] park, POSTECH, 82-11-521-8909, [email protected] han Kim, POSTECH, 82-54-279-2101, [email protected] Kim, NC Central Univ., 919-530-6451, [email protected] Kuk Koh, Chrysan Ind., [email protected] ok lee, Rockefeller Univ., 212-327-8617, [email protected] chin suh, 610-678-0534, [email protected] Young han, Duke Univ., 919-660-2575, [email protected] sup hyun, Polymer Processing Institute, [email protected] Kim, K-JIST, 703-663-8803, [email protected] Won suh, NC State Univ., 919-515-6580, [email protected] doo-Young ryu, UC Davis, 530-752-8954, [email protected] ahn, Fuzbien Tech. Institute, [email protected] chul chun, 301-598-3396, [email protected] dong lee, Univ. of Illinois, Urbana-Champaign, [email protected] taik (Thomas) hahn, 310-825-2383, [email protected] ho chung, Argonne National Lab., [email protected] ho sung, Tufts University, 617-627-3447, [email protected] chan i. chung, Rensselaer Polytechnic Institute, [email protected] Kim, JPL/NASA, 818-354-8612, [email protected] Won lee, Univ. of Maryland, 301-405-1128, [email protected] K. Kang, IBM T.J. Watson Research Ctr., [email protected] Wayne lee, Univ. of Rhode Island, [email protected] lee, IBM T.J. Watson Research Ctr., 914-945-3070, [email protected] Ji, North Carolina State Univ., [email protected] hoon Kim, The Boeing Company, 425-786-7723, [email protected]

ex-presidents (deceased)shoon Kyung Kiminyong hamchong Wha pyunhogil KimJe hyun KimKyungsik Kang soon Kyu KimKwang-hae (Kane) Kim

KSEA LETTERS Vol. 40 No. 4 June 201254

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Page 56: KSEA LETTERSksea.org/KSEALetters/Vol_40_4_2012.pdf · His research is focused on developing a new method to improve the resolu-tion of fiber orientation maps called R2*-based fiber

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