KSPE_Medical_Apps_July_20_2016_Busan Print Ver

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IN 1895 WILHELM RONTGEN DISCOVERED THE X-RAY, AND MADE BONES VISUALIZATION POSSIBLE, BUT ONLY TWO DECADES AGO, BIOMEDICAL PROTOTYPING BECAME A REALITY

7/9/2016Guy J. Ofek - Mcor Technologies 1

ARE YOU AM-ABLED?MEDICAL APPLICATIONS OF ADDITIVE MANUFACTURING


GUY J. OFEK - BIO DATA

� SALES DIRECTOR ASIA PACIFIC & JAPAN

� 13 YEARS WORK EXPERIENCE IN ASIA

� 8 YEARS IN THE AM INDUSTRY

� 5 YEARS WITH STRATASYS

� 2.5 YEARS IN SEOUL

� LLB, MBA


Guy J. Ofek - Mcor Technologies 7/9/2016 4


1. SURGICAL PLANNING, EDUCATION &

COMMUNICATION

2. HEARING AIDS

3. DENTAL DEVICES

4. MEDICAL DEVICES

5. SURGICAL TOOLS & GUIDES

6. SURGERY IMPLANTS

7. NOVEL APPLICATIONS


ORTHOPEDICS

ORAL & MAXILLOFACIAL

CARNIO MAXILLOFACIAL

ONCOLOGY

IMPLANTOLOGY

NEUROSURGERY

PLASTIC SURGERY

FORENSIC MED.

DENTISTRY


WHAT IS ADDITIVE MANUFACTURING ?


WHAT IS ADDITIVE MANUFACTURING ?

“ THE PROCESS OF MAKING A PHYSICAL OBJECT FROM

THREE-DIMENSIONAL DIGITAL MODEL, TYPICALLY BY LAYING

DOWN MANY SUCCESSIVE THIN LAYERS OF MATERIAL. “

ALSO KNOWN AS:

• RAPID PROTOTYPING

• 3D PRINTING

• DIGITAL FABRICATION


TECHNOLOGIES

• STEREOLITHOGRAPHY (SLA)

• SELECTIVE LASER MELTING (SLM)

• SELECTIVE LASER SINTERING (SLS)

• DIGITAL LIGHT PROCESSING (DLP)

• ELECTRONIC BEAM MELTING (EBM)

• FUSED DEPOSITION MODELING (FDM)

• LAMINATED OBJECT MANUFACTURING (LOM)

• INKJET BASED TECHNOLOGIES (POLYJET, POWDER BINDING)


THE PROCESS


From CT / MRI Designing with CAD Anatomical

Engineering

Part production

using AM

USA

3D Doctors

Analyze

Velocity Pro

AustraliaAnatomics

Germany Julius

CanadaSliceOmatic

Belgium Mimics

CT DATA CONVERSION INTO STL


Guy J. Ofek - Mcor Technologies 7/9/2016 13

Source: Patent Insight Pro

FIVE C’S

• COMPRESSION OF TIME

• COST OF ERROR

• CONFIDENTIALITY

• CREATIVITY

• COMMUNICATION


TOP 4 BENEFITS OF AM


MORE COMPLEX DESIGN CAPABILITY

REDUCE LEAD TIME OF PARTS

IMPROVEMENTS IN MANUFACTURING EFFICIENCIES

HIGHER QUALITY, INTEGRATED PRODUCTS

79%

76%

42%

20%

Source: Stratasys Direct Manufacturing

SURGICAL PLANNING, EDUCATION AND COMMUNICATION


PRE SURGERY PLANNING


PRE SURGERY COMMUNICATION

3D PRINTED KIDNEYS -SIMULATED CANCER

SURGERY

• CT - TO PRODUCED A 3D SCAN OF

THE PATIENT’ KIDNEYS

• DICOM TO STL

• AM OF THE 3D MODEL

• THE TRANSPARENT MODEL ALLOW

SURGEONS TO SEE EXACTLY WHERE

THE PATIENT BLOOD VESSELS ARE

POSITIONED

7/9/2016Guy J. Ofek - Mcor Technologies 18Source: Medical News Today

3D PRINTED LIVER -SIMULATED CANCER SURGERY


• Dr. Maki Sugimoto, a surgeon and professor at the Kobe University School of Medicine, is using 3D Printing to model his patients’ organs in preparation for surgeries.

• Hi generate life-size models of kidneys, livers and other organs that are medically accurate.

• Multiple materials (the outer structure of models can be rendered transparent) help him see deep into an organ’s tissue where he can diagnose cancer, find scar tissues and build a plan for surgical operations.

FULL COLOR PAPER 3D MODELS –AESTHETIC SURGERY

7/9/2016Guy J. Ofek - Mcor Technologies 20Source: Mcor Technologies

FULL COLOR PAPER 3D MODELS

• FOR TEACHING

• BETTER LOOK & FEEL

• LOW RUNNING COSTS

• USED IN THE OR

• CAN BE STERILIZED

7/9/2016Guy J. Ofek - Mcor Technologies 21Source: Mcor Technologies

SURGICAL BIO MODELS

• OBTAINING CADAVERS BECAME DIFFICULT

• CREATING CUSTOM BIO MODELS IS A PAINSTAKING

PROCESS, TAKES A LONG TIME AND IS COSTLY

• CENTER OF BIOMEDICAL AND TECHNOLOGY INTEGRATION,

UNI. OF MALAYA IN MALAYSIA



CBMTI VIDEO

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WE HAVE GONE FROM BEING ONLY ABLE TO MOLD TITANIUM PLATES FOR CRANIAL IMPLANTS TO BEING ABLE TO CREATE BIO MODELS WITH PATHOLOGY FROM ACTUAL PATIENT IMAGING DATA … ENDOSCOPIC NEUROSURGICAL PROCEDURES ARE SIMULATED AS CLOSELY AS POSSIBLE

WITH THESE 3D PRINTED MODELS

KUMAR BALAKRISHNAN, OPERATIONS MANAGER, CBMTI


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AS 3D PRINTER TECHNOLOGY IMPROVES, THESE MACHINES WILL PROVIDE THE POSSIBILITY FOR NEWER, MORE COMPLEX MODELS TO BE CREATED, ALLOWING AN

IMPROVED TRAINING EXPERIENCE. … 3D MODELS OF THE FUTURE MAY ALLOW THE POSSIBILITY TO PERFORM ENTIRE OPERATIONS FROM START TO FINISH, MAKING FOR A

REALISTIC SIMULATOR

PROF. AND CONSULTANT VICKNES WARAN, NEUROSURGEON, CBMTI


SURGICAL PLANNING -CONJOINED TWINS

• POLYJET TECHNOLOGY USED IN 2002

• SAVED NEW BORN TWINS CONNECTED IN THEIR HEADS

• OPERATION TOOK 22 HRS INSTEAD OF 97 HRS


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FINAL DETAILS IN THE MODELS PROVED ESPECIALLY CRITICAL TO ACHIEVING SUCCESS, SINCE THE

SURGEONS NEEDED TO LOOK INSIDE THE MODEL AND PLAN THE REROUTING OF THE BLOOD VESSEL

HENRY K. KAWAMOTO JR., M.D., D.D.S., UCLA


CARNIOPLASTY SURGICAL SOLUTION

FRONT TEMPORAL CRANIAL DEFECT DUE TO TRAFFIC ACCIDENT



Polyjet Model

Scan Skull by CT

Convert output to STL

Print skull or missing plate

MOLD COPY USING PMMA


1. PLANNING


Incision PlanningDefect Exposed

2. PREPARING


Trimming Mini Plate PlacementDrilling Slots

3. IMPLANTING


Repositioning Final FixationDrilling Skull For

Screw

RADIOGRAPHIC IMAGE


FINAL RESULT


THE PATIENT TODAY


TUMOR OPERATION


TUMOR OPERATION


Negative template

PRE OP VS. POST OP MOKUP


MAXILLARY OPERATION


From model to surgery

MAXILLARY OPERATION

7/9/2016Guy J. Ofek - Mcor Technologies 41From model to surgery

HEARING AIDS


THE PROCESS

Source: Deloitte TMT Predictions 2015 7/10/2016Guy J. Ofek - Mcor Technologies 43

MATERIALS


TECHNOLOGIES


DENTAL DEVICES


THE PROCESS


PRINT TRAY



CLEAR ALIGNERS


IMPLANT GUIDES

DRILLING GUIDES


MEDICAL DEVICES


PRODUCT DEVELOPMENT (PROTOTYPING)


MEDICAL DEVICES


MEDICAL IMPLANTS


SURGERY TOOLS & GUIDES


MEDICAL TOOLS


ORTHOPEDIC SURGERY

• DRILL GUIDES

• ALIGNERS

• FASTENERS


Drill Guide produced by Solid Concepts

Surgical Guide produced by Materialise

DANAMED INC. ’S PATHFINDER


• DMLS TOOL FOR ACL REPAIR SURGERIES

• SURGICAL TOOL SPECIALLY SHAPED TO

MATCH THE ANATOMY OF THE KNEE

• MADE OF INCONEL 718 MATERIAL FOR

BIOCOMPATIBILITY, SURFACE FINISH, OIL

RESISTANCE

• SIGNIFICANT COST EFFICIENCY ACHIEVED

• FDA REGISTERED CLASS 1 MEDICAL PRODUCT

Source: Stratasys Direct Manufacturing

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... BY OFFERING DANAMED 97% COST SAVINGS OVER CONVENTIONAL MANUFACTURING METHODS, 3D PRINTING HAS DEMONSTRATED ITS BUSINESS

VALUE IN BRINGING COMPLEX, HIGH QUALITY PARTS TO MARKET.

JOHN SELF, PROJECT ENGINEER, STRATASYS DIRECT MANUFACTURING


SURGERY IMPLANTS


3D PRINTED TITANIUM STERNUM AND RIBS

7/9/2016Guy J. Ofek - Mcor Technologies 62Source: Tech Insider


CSIRO VIDEO


• FIRST EVER 3D PRINTED VERTEBRA

• NO SURGICAL CEMENT OR

SCREWS WERE REQUIRED GIVEN

THE PERFECT FIT

• FASTER RECOVERY AND EASIER

MOBILITY

• TITANIUM POWDER

• TINY PORES WILL ALLOW BONE TO

GROW INSIDE THE VERTEBRA

Source: Reuters

MEDICAL IMPLANTS

• ACETABULAR CUPS

• REVISION CUPS

• AUGMENTS

• FEMORAL STEMS

• CMF

• SPINE

• TIBIAL TRAYS


ACETABULAR CUP IMPLANT

CE CERTIFIED & FDA CLEARED IMPLANTS

• ACETABULAR CUPS WITH INTEGRATED TRABECULAR

STRUCTURES SINCE 2007

• IMPLANTS WITH FDA CLEARANCE SINCE 2010

• > 30,000 CUPS IMPLANTED

• 2% OF THE GLOBAL PRODUCTION OF ACETABULAR CUPS

IS NOW MANUFACTURED WITH EBM TECHNOLOGY

7/10/2016Guy J. Ofek - Mcor Technologies 66Source: Materialise

NOVEL APPLICATIONS


LOW COST PROSTHETICS

7/9/2016Guy J. Ofek - Mcor Technologies 68Source: MedGadget

OCULAR (EYE) PROSTHESIS

FRIP DESIGN + MANCHESTER METRO UNI.

� REDUCE PRODUCTION TIME OF PROSTHESES

�MATCH EXISTING QUALITY

� COST EFFECTIVE ALTERNATIVE

� IMPROVE CONSISTENCY IN SUPPLY


Source: 3D Printing Industry

SKULL TRANSPLANT

7/9/2016Guy J. Ofek - Mcor Technologies 70Source: Medical Daily

22 YO WOMAN IN THE NETHERLANDS SUFFERED FROM CONDITIONS THAT THICKENS HER BONE STRUCTURE ESPECIALLY IN THE SKULL

HER ENTIRE SKULL REPLACED WITH A 3D PRINTED PLASTIC IMPLANT

THANK YOUGUY J. OFEK

@ [email protected]

M: +82 10 6828 9889


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KSPE_Medical_Apps_July_20_2016_Busan Print Ver