LactoClear - Overview finished products

CELL BIOTECH EUROPE A/S | www.duolac.com | [email protected]

Retail product description Product: LactoClear™ Cream 20ml - Natural Acne Therapy


Retail product description Product: LactoClear™ Cream 20ml - Natural Acne Therapy

20-09-2010/jg

Claims: Natural Acne Therapy, Natural for Acne,

Sold as: Private label. With Lactopad brand name on the package

Packing: MOQ: 20.000. White tube with label packed in 4 colour carton box with insert

Item / case

number:

Item number: 96300

Formulation ID: 503566

Approvals/ certificates

Lactopad™ active component is manufactured under GMP conditions at Cell Biotech Co. Ltd. Korea. The Lactopad private label products are manufactured in Denmark by Derma Pharm.

Usage: Locally on unclear, irritated and erythematus skin, on individual spots or when needed on larger areas such as face, chest or back. Apply thin layer on problematic area in the morning and evening. In the beginning the skin can blish and feel itchy and tight.

Active content:

Bacteriocin: 4,0% Lactopad CBT-SL5 is one of the bacteriocins derived from Enterococcus faecalis SL5.

Ingredients:

0010 Aqua: 1102 Lipex Shea/Butyrospermum Parkii: vegetable softener 3143 Jojoba oil organic / Simmondsia Chinensis seed oil: vegetable softener 2404

Glycerin / Glycerin: moisturiser 4276 Enterococcus Faecalis Ferment – Lactopad™ 1332 AXOL C 62 / Glyceryl Stearate Citrate: emulsifier 1345 Lanette 18 / Stearyl Alcohol: emulsifier 2224 Microcare BDP / Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid: Preservative agents 1411 Carbopol Ultrez-10 / Carbomer: viscosity stabilizer 2104 Allantoin / Allantoin: anti-irritant 2506 Natrium hydrocyd 26% / Sodium Hydroxide: pH regulator

General information:

Use as symptomatic treatment or prevention of acne in adults, and children. Lactopad is a dried form of cell-free supernatant of a probiotic culture, the lactic acid bacterium Enterococcus faecalis SL5, with an antibacterial activity against Propionibacterium acnes, a key causative agent of acne.

Lactopad has a selective property, that is, it kills only target microbes selectively. Mechanism: Lactopad has simple primary structure that is composed of polypeptide

chain. Hydrophobic aminoterminal end of the peptides enter the cell membrane and makes a hole, and it kill the target microbes by changing the membrane potential. Please refer to clinical study:

1. Antimicrobial Activity of Enterocins from Enterococcus faecalis SL-5 against Propionibacterium acnes, the Causative Agent in Acne Vulgaris, and its Therapeutic Effect (ID 6A)

2. CBT-SL5, a Bacteriocin from Enterococcus faecalis, Suppresses the Expression of Interleukin-8 Induced by Propionibacterium acnes in Cultured Human Keratinocytes (ID 6B)

Available documents:

01 Lactopad ™ specification and MSDS and all raw material specifications 02 CTFA registration, ISO 9001:2000 and ISO 14001. EUR1 cert 03 Challenge test (June 2010) 04 Production dokumenters (Production flow diagram etc)

05 Product formulation

06 Packing documents


Retail product description Product: LactoClear™ Cream GMP 20ml - Natural Acne Therapy


Retail product description Product: LactoClear™ Cream GMP 20ml - Natural Acne Therapy

15-10-2010/jg



Packing: MOQ: 25.000. White tube with label packed in 4 colour carton box with insert

Item / case

number:

Item number: 96400

Formulation ID: XL.07


Lactopad™ active component is manufactured under GMP conditions at Cell Biotech Co. Ltd. Korea. The Lactopad private label products are manufactured in Poland under GMP by Polfarmex.

Usage: Locally on unclear, irritated and erythematus skin, on individual spots or when needed on larger areas such as face, chest or back. Apply thin layer on problematic area in the morning and evening. In the beginning the skin can blish and feel itchy and tight.

Active content:


Ingredients:

Aqua, Glycerin, Isohexadecane, Maltodextrin (and) Enterococcus Faecalis Ferment, Glyceryl Stearate (and) Ceteareth-20 (and) Ceteareth-12 (and) Cetearyl Alcohol

(and) Cetyl Palmitate, Cetearyl Alcohol, Ethylhexyl Stearate, Glyceryl Stearate, Hydroxypropyl Starch Phosphate, Isopropyl Palmitate, Panthenol, Tocopheryl Acetate, Caprylyl Glycol (and) Caprylhydroxamic Acid (and) Glycerin.

General

information:

Use as symptomatic treatment or prevention of acne in adults, and children.

Lactopad is a dried form of cell-free supernatant of a probiotic culture, the lactic acid bacterium Enterococcus faecalis SL5, with an antibacterial activity against Propionibacterium acnes, a key causative agent of acne. Lactopad has a selective property, that is, it kills only target microbes selectively. Mechanism: Lactopad has simple primary structure that is composed of polypeptide

chain. Hydrophobic aminoterminal end of the peptides enter the cell membrane and makes a hole, and it kill the target microbes by changing the membrane potential.

Please refer to clinical study:


2. CBT-SL5, a Bacteriocin from Enterococcus faecalis, Suppresses the Expression of Interleukin-8 Induced by Propionibacterium acnes in Cultured Human Keratinocytes (ID 6B)

Available

documents:

01 Lactopad ™ specification and MSDS and all raw material specifications

02 CTFA registration, ISO 9001:2000 and ISO 14001. EUR1 cert 03 Challenge test (June 2010) 04 Production documenters 05 Product formulation 06 Packing documents


Retail product description Product: LactoClear™ skin tonic 50ml - Natural Acne Therapy


Retail product description Product: LactoClear™ skin tonic 50ml

20-09-2010/jg



Packing: MOQ: 20.000. Frostet PP bottle with white flip top capsule. 4 colour label and 4 colour carton box (pantone colours). Contains 50ml skin tonic

Item / case number:

Item number: 96500 Formulation ID: 5381


Lactopad™ active component is manufactured under GMP conditions at Cell Biotech Co. Ltd. Korea. The Lactopad private label products are manufactured in Denmark by ABC A/S

Usage: Locally on unclear, irritated and erythematus skin. When needed on larger areas such as face, chest or back. Apply thin layer on problematic area in the morning and evening. In the beginning the skin can blish and feel itchy and tight.

Active content:


Ingredients:

Aqua, Glycerin, PEG-7 Glyceryl Cocoate, Maltodextrin, Enterococcus Faecalis Ferment (Lactopad), Sodium PCA, PEG-40 Hydrogenated Castor Oil, Niacinamide,

Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid, Ehylhexylglycerin


Use as symptomatic treatment or prevention of acne in adults, and children. Lactopad is a dried form of cell-free supernatant of a probiotic culture, the lactic acid bacterium Enterococcus faecalis SL5, with an antibacterial activity against

Propionibacterium acnes, a key causative agent of acne. Lactopad has a selective property, that is, it kills only target microbes selectively. Mechanism: Lactopad has simple primary structure that is composed of polypeptide chain. Hydrophobic aminoterminal end of the peptides enter the cell membrane and makes a hole, and it kill the target microbes by changing the membrane potential.


1. Antimicrobial Activity of Enterocins from Enterococcus faecalis SL-5 against

Propionibacterium acnes, the Causative Agent in Acne Vulgaris, and its Therapeutic Effect (ID 6A)

2. CBT-SL5, a Bacteriocin from Enterococcus faecalis, Suppresses the Expression of Interleukin-8 Induced by Propionibacterium acnes in Cultured

Human Keratinocytes (ID 6B)


01 Lactopad ™ specification and MSDS and all raw material specifications 02 CTFA registration, ISO 9001:2000 and ISO 14001. EUR1 cert 03 Challenge test (June 2010)

04 Production documents (Production flow diagram etc) 05 Product formulation 06 Packing documents


Retail product description Product: LactoClear™ Roll on spot stick 9,5ml - Natural Acne Therapy


Retail product description Product: LactoClear™ Roll on spot stick 9,5ml net

20-10-2010/jg


Sold as: Private label cosmetic. With Lactopad brand name on the package

Packing: MOQ: 20.000. Glass container with dosage cap. Label packed in 4 colour carton box. Contain 9,5ml

Item / case number:

Item number: 96525 Formulation ID: 5390/2401


Lactopad™ active component is manufactured under GMP conditions at Cell Biotech Co. Ltd. Korea. The Lactopad private label products are manufactured in Denmark by ABC A/S.

Usage: Locally on unclear, irritated and erythematus skin and individual spots. Apply layer on problematic area in the morning and evening. In the beginning the skin can blish and feel itchy and tight.

Active content:


Ingredients:

Aqua, Glycerin, Maltodextrin, Enterococcus Faecalis Ferment (Lactopad), Sodium PCA, Niacinamide, Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid,

Ehylhexylglycerin, Xanthan Gum, Sodium Hydroxide


Use as symptomatic treatment or prevention of acne in adults, and children. Lactopad is a dried form of cell-free supernatant of a probiotic culture, the lactic acid bacterium Enterococcus faecalis SL5, with an antibacterial activity against

Propionibacterium acnes, a key causative agent of acne. Lactopad has a selective property, that is, it kills only target microbes selectively. Mechanism: Lactopad has simple primary structure that is composed of polypeptide chain. Hydrophobic aminoterminal end of the peptides enter the cell membrane and makes a hole, and it kill the target microbes by changing the membrane potential.


1. Antimicrobial Activity of Enterocins from Enterococcus faecalis SL-5 against

Propionibacterium acnes, the Causative Agent in Acne Vulgaris, and its Therapeutic Effect (ID 6A)

2. CBT-SL5, a Bacteriocin from Enterococcus faecalis, Suppresses the Expression of Interleukin-8 Induced by Propionibacterium acnes in Cultured

Human Keratinocytes (ID 6B)


01 Lactopad ™ specification and MSDS and all raw material specifications 02 CTFA registration, ISO 9001:2000 and ISO 14001. EUR1 cert 03 Challenge test (June 2010)

04 Production documents (Production flow diagram etc) 05 Product formulation 06 Packing documents


Retail product description Product: BioClear™ wet wipes 4,0g - Natural Acne Therapy


Retail product description Product: BioClear™ wet wipes 4g

20-09-2010/jg


Sold as: Private label cosmetic. With Lactopad brand name on the package

Packing: MOQ: 250.000 single wet wipes. Sachet 70x100 mm, wipe 170x180mm, 4g skin tonic on wet wipe, 14 wipes per carton box. 4 colour print on carton box.

Item / case number:

Item number: 96525 Formulation ID: ST 2402


Lactopad™ active component is manufactured under GMP conditions at Cell Biotech Co. Ltd. Korea. The Lactopad private label products are manufactured in Denmark by ABC.

Usage: Locally on unclear, irritated and erythematus skin and individual spots. Apply layer on problematic area in the morning and evening. In the beginning the skin can blish and feel itchy and tight.

Active content:


Ingredients:

Aqua, Glycerin, PEG-7 Glyceryl Cocoate, Maltodextrin, Enterococcus Faecalis Ferment, Sodium PCA, PEG-40 Hydrogenated Castor Oil, Niacinamide,

Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid, Ehylhexylglycerin, Sodium Hydroxide


Use as symptomatic treatment or prevention of acne in adults, and children. Lactopad is a dried form of cell-free supernatant of a probiotic culture, the lactic

acid bacterium Enterococcus faecalis SL5, with an antibacterial activity against Propionibacterium acnes, a key causative agent of acne. Lactopad has a selective property, that is, it kills only target microbes selectively. Mechanism: Lactopad has simple primary structure that is composed of polypeptide chain. Hydrophobic aminoterminal end of the peptides enter the cell membrane and

makes a hole, and it kill the target microbes by changing the membrane potential. Please refer to clinical study:


2. CBT-SL5, a Bacteriocin from Enterococcus faecalis, Suppresses the

Expression of Interleukin-8 Induced by Propionibacterium acnes in Cultured Human Keratinocytes (ID 6B)


01 Lactopad ™ specification and MSDS and all raw material specifications 02 CTFA registration, ISO 9001:2000 and ISO 14001. EUR1 cert

03 Challenge test (June 2010) 04 Production documents (Production flow diagram etc) 05 Product formulation 06 Packing documents

Documents

LactoClear - Overview finished products