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1 ACQUITY UPLC Leak Sensor maintenance instructions Contents: Topic Page Overview 2 Enabling the leak sensors in the software 4 Resolving leak sensor errors in general 5 Resolving binary solvent manager leak sensor errors 5 Resolving sample manager leak sensor errors 11 Resolving column heater leak sensor errors 16 Resolving column heater leak sensor errors (door fully opened) 21 Resolving column manager leak sensor errors 26 Resolving detector leak sensor errors 31 Replacing the binary solvent manager’s leak sensor 35 Replacing the sample manager’s leak sensor 39 Replacing the column heater’s leak sensor 42 Replacing the column heater’s leak sensor (door fully opened) 46 Replacing the column manager’s leak sensor 49 Replacing the detector’s leak sensor 53 71500082506, Rev. A Waters and ACQUITY UPLC are registered trademarks, and THE SCIENCE OF WHAT’S POSSIBLE is a trademark of Waters Corporation. All other trademarks are the sole property of their respective owners. Copyright © 2007 Waters Corporation.

Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

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Page 1: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

ACQUITY UPLC Leak Sensor maintenance instructions

Contents:

Topic PageOverview 2Enabling the leak sensors in the software 4Resolving leak sensor errors in general 5Resolving binary solvent manager leak sensor errors 5Resolving sample manager leak sensor errors 11Resolving column heater leak sensor errors 16Resolving column heater leak sensor errors (door fully opened) 21Resolving column manager leak sensor errors 26Resolving detector leak sensor errors 31Replacing the binary solvent manager’s leak sensor 35Replacing the sample manager’s leak sensor 39Replacing the column heater’s leak sensor 42Replacing the column heater’s leak sensor (door fully opened) 46Replacing the column manager’s leak sensor 49Replacing the detector’s leak sensor 53

71500082506, Rev. A

1

Waters and ACQUITY UPLC are registered trademarks, andTHE SCIENCE OF WHAT’S POSSIBLE is a trademark of Waters Corporation.

All other trademarks are the sole property of their respective owners.Copyright © 2007 Waters Corporation.

Page 2: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

OverviewLeak sensors in the drip trays of ACQUITY UPLC® system instruments continuously monitor the instruments for leaks. A leak sensor stops system flow when its optical sensor detects about 1.5 mL of accumulated, leaked liquid in its surrounding reservoir. At the same time, the ACQUITY UPLC Console displays an error message alerting you that a leak has developed.Notes:

• ACQUITY UPLC detectors that have a leak sensor include the TUV, PDA, ELS, FLR, SQ, and TQ detectors.

• The ACQUITY UPLC sample organizer and HPLC column heater/cooler do not have leak sensors.

Leak sensor components

HousingT-bar

Prism

Serrations

Ribbon cable

Connector

2

Page 3: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Typical location of leak sensors

Column heater leak sensor

Detector leak sensor

Sample manager leak sensor

Binary solvent manager leak sensor

3

Page 4: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Enabling the leak sensors in the softwareTip: When you power-on the system, the leak sensors default to disabled if they were never previously enabled.

To enable the leak sensors:

1. On the ACQUITY UPLC Console system page, select Control > Leak Sensors.

Leak Sensors dialog box

2. To enable the leak sensor for an individual instrument, click the status, to the left of the instrument description.Tip: To enable all leak sensors, click Enable All.

Click to enable or disable individual instrument leak sensors

4

Page 5: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Resolving leak sensor errors in generalWhen a leak sensor detects a leak, the system flow stops, an alarm sounds, an error message appears on the affected instrument’s information window in the ACQUITY UPLC Console, and, if Connections INSIGHT is installed, an alert is sent. You must clear a leak error before system flow resumes.Resolving a leak error involves this procedure:

• locating the source of the leak• repairing the leak• removing the leak sensor from the instrument’s drip tray• drying the leak sensor• drying the liquid in the leak sensor reservoir• reinstalling the leak sensor• and resetting the instrument

Resolving binary solvent manager leak sensor errorsAfter approximately 1.5 mL of liquid accumulates in the binary solvent manager’s leak sensor reservoir, an alarm sounds, indicating that the leak sensor detected a leak.

Required materials

• Chemical-resistant, powder-free gloves• Cotton swabs• Nonabrasive, lint-free wipes

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid scratching or damaging the leak sensor• do not allow buffered solvents to accumulate and dry on it.• do not submerge it in a cleaning bath.

5

Page 6: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

To resolve a binary solvent manager leak sensor error:

1. View the Leak Sensors dialog box in the ACQUITY UPLC Console to confirm that the binary solvent manager leak sensor detected a leak.Tip: If a leak was detected, a “Leak Detected” error message appears.

2. Open the binary solvent manager’s door, gently pulling its right edge toward you.

3. Locate the source of the leak, and make the repairs necessary to stop the leak.

4. Turn the vent tube retainer to the right, and then lift the A-vent and B-vent tubes out of the drip tray by pulling up on them and moving them to the left of the leak sensor.

TP02884

Turn vent tube retainer to right

Pull up on vent tubes and move them to the left

Leak sensor

6

Page 7: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

5. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.Tip: If the leak sensor cannot be easily manipulated after being removed from its reservoir, detach the connector from the front of the instrument (see page 1-35).

6. Use a nonabrasive, lint-free wipe to dry the leak sensor prism.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

TP02891

Prism

Lint-free wipe

7

Page 8: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

7. Roll up a nonabrasive, lint-free wipe, and use it to absorb the liquid from the leak sensor reservoir and its surrounding area.

8. With a cotton swab, absorb any remaining liquid from the corners of the leak sensor reservoir and its surrounding area.

Rolled up lint-free wipe

Leak sensor reservoir

Cotton swab

Leak sensor reservoir

8

Page 9: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

9. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

10. Reinsert the A-vent and B-vent tubes into the drip tray.

TP02892

TP02888

TP02889

Slot in leak sensor reservoir

Leak sensor installed in reservoir

T-bar

9

Page 10: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

11. Turn the vent tube retainer, which holds the A-vent and B-vent tubing in place, to the left.

12. In the ACQUITY UPLC Console, select Binary Solvent Manager from the system tree.

13. In the binary solvent manager information window, click Control > Reset BSM to reset the binary solvent manager.

TP02884

Vent tube retainer

Vent tubes

Leak sensor

10

Page 11: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Resolving sample manager leak sensor errorsAfter approximately 1.5 mL of liquid accumulates in the sample manager’s leak sensor reservoir, an alarm sounds, indicating that the leak sensor detected a leak.

Tip: The sample manager is the only ACQUITY UPLC instrument with two leak sensors, bottom and top, called the sample manager leak sensor and the column heater leak sensor, respectively.

Required materials

• Chemical-resistant, powder-free gloves• Cotton swabs• Nonabrasive, lint-free wipes

To resolve a sample manager leak sensor error:

1. View the Leak Sensors dialog box in the ACQUITY UPLC Console to determine which of the sample manager’s two leak sensors detected a leak.Rules:• The error message “Leak Detected” means the sample manager leak

sensor, on the sample manager’s bottom right corner, detected the leak.

• The error message “Leak Detected (Column)” means the column heater leak sensor, on the sample manager’s top right corner, detected the leak.

2. Slide out the sample manager fluidics tray.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid scratching or damaging the leak sensor:• do not allow buffered solvents to accumulate and dry on it.• do not submerge it in a cleaning bath.

11

Page 12: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Locate the source of the leak, and make the repairs necessary to stop the leak.

4. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

Tip: If the leak sensor cannot be easily manipulated after being removed from its reservoir, detach the connector from the front of the instrument (see page 1-39).

5. Use a nonabrasive, lint-free wipe to dry the leak sensor prism.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

TP02891

Prism

Lint-free wipe

12

Page 13: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

6. Roll up a nonabrasive, lint-free wipe, and use it to absorb the liquid from the leak sensor reservoir and its surrounding area.

Rolled up lint-free wipe

Leak sensor reservoir

13

Page 14: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

7. With a cotton swab, absorb any remaining liquid from the corners of the leak sensor reservoir and its surrounding area.

Cotton swab

Leak sensor reservoir

14

Page 15: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

8. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

9. In the ACQUITY UPLC Console, select Sample Manager from the system tree.

10. In the sample manager information window, click Control > Reset SM to reset the sample manager.

TP02907

TP02892

T-bar

Leak sensor installed in reservoir

Slot in leak sensor reservoir

15

Page 16: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Resolving column heater leak sensor errorsAfter approximately 1.5 mL of liquid accumulates in the column heater’s leak sensor reservoir, an alarm sounds, indicating that the leak sensor detected a leak.

Tip: Small column leaks can be undetectable because they can evaporate before reaching the leak sensor reservoir.

Required materials

• Chemical-resistant, powder-free gloves• Cotton swabs• Nonabrasive, lint-free wipes

To resolve a column heater leak sensor error:

1. View the Leak Sensors dialog box in the ACQUITY UPLC Console to determine which of the sample manager’s two leak sensors detected a leak.Rules:• The error message “Leak Detected” means the sample manager leak

sensor, on the sample manager’s bottom right corner, detected the leak.

• The error message “Leak Detected (Column)” means the column heater leak sensor, on the sample manager’s top right corner, detected the leak.

2. Open the column heater’s door.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid scratching or damaging the leak sensor:• do not allow buffered solvents to accumulate and dry on it.• do not submerge it in a cleaning bath.

16

Page 17: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Locate the source of the leak, and make the repairs necessary to stop the leak.Tip: Liquid from a detector leak can sometimes accumulate in the column heater leak sensor reservoir and cause the column heater leak sensor alarm to sound. Always inspect the detector when attempting to locate the source of a leak.

4. Remove any solvent lines routed between the column heater door and hinge.

5. Push down on the metal clip at the bottom, left-hand side of the column heater to release the door, and then pull the door toward you.

6. Swing the door fully to the right.

TP02596

Metal clip

Column heater door

Column heater door

17

Page 18: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

7. Remove the leak sensor from its reservoir by grasping it by its serrations, pulling upward on it, and tilting it to the left.

Tip: If the leak sensor cannot be easily manipulated after being removed from its reservoir, detach the connector from the front of the instrument (see page 1-42).

8. Use a nonabrasive, lint-free wipe to dry the leak sensor prism.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

TP02891

Prism

Lint-free wipe

18

Page 19: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

9. Roll up a nonabrasive, lint-free wipe, and use it to absorb the liquid from the leak sensor reservoir and its surrounding area.

10. With a cotton swab, absorb any remaining liquid from the corners of the leak sensor reservoir and its surrounding area.

Rolled up lint-free wipe

Leak sensor reservoir

Cotton swab

Leak sensor reservoir

19

Page 20: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

11. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

12. In the ACQUITY UPLC Console, select Sample Manager from the system tree.

13. In the sample manager information window, click Control > Reset SM to reset the sample manager.

TP02909

TP02892

Slot in leak sensor reservoir

T-bar

Leak sensor installed in reservoir

20

Page 21: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Resolving column heater leak sensor errors (door fully opened)After approximately 1.5 mL of liquid accumulates in the column heater’s leak sensor reservoir, an alarm sounds, indicating that the leak sensor detected a leak.

Tip: Small column leaks can be undetectable because they can evaporate before reaching the leak sensor reservoir.

Required materials

• Chemical-resistant, powder-free gloves• Cotton swabs• Nonabrasive, lint-free wipes

To resolve a leak sensor error for a column heater with its door fully open:

1. View the Leak Sensors dialog box in the ACQUITY UPLC Console to determine which of the sample manager’s two leak sensors detected a leak.Rules:• The error message “Leak Detected” means the sample manager leak

sensor, on the sample manager’s bottom right corner, detected the leak.

• The error message “Leak Detected (Column)” means the column heater leak sensor, on the sample manager’s top right corner, detected the leak.

2. Locate the source of the leak, and make the repairs necessary to stop the leak.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid scratching or damaging the leak sensor:• do not allow buffered solvents to accumulate and dry on it.• do not submerge it in a cleaning bath.

21

Page 22: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Tip: Liquid from a detector leak can sometimes accumulate in the column heater leak sensor reservoir and cause the column heater leak sensor alarm to sound. Always inspect the detector when attempting to locate the source of a leak.

3. Slide out the sample manager fluidics tray.

4. Using one finger from each hand, remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

22

Page 23: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Alternative: Leave the leak sensor in place, use the syringe included the binary solvent manager Startup Kit to remove the liquid from the leak sensor reservoir, and proceed to step 9.

5. Tilt the leak sensor to the right and remove it from under the drip tray.

Tip: If the leak sensor cannot be easily manipulated after being removed from its reservoir, detach the connector from the front of the instrument (see page 1-42).

TP02931

Push up on syringe plunger

Drain hole

Leak sensor tilted to right

23

Page 24: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

6. Use a nonabrasive, lint-free wipe to dry the leak sensor prism.

7. Insert a cotton swab through the drip tray drain hole and absorb any remaining liquid from the leak sensor reservoir and its surrounding area.

Prism

Lint-free wipe

Cotton swab

Drain hole

24

Page 25: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

8. Using one finger from each hand, align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

9. Slide the fluidics tray closed.

10. In the ACQUITY UPLC Console, select Sample Manager from the system tree.

11. In the sample manager information window, click Control > Reset SM to reset the sample manager.

T-bar

25

Page 26: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Resolving column manager leak sensor errorsAfter approximately 1.5 mL of liquid accumulates in the column manager’s leak sensor reservoir, an alarm sounds, indicating that the leak sensor detected a leak.

Tip: Small column leaks can be undetectable because they can evaporate before reaching the leak sensor reservoir.

Required materials

• Chemical-resistant, powder-free gloves• Cotton swabs• Nonabrasive, lint-free wipes

To resolve a column manager leak sensor error:

1. View the Leak Sensors dialog box in the ACQUITY UPLC Console to confirm that the column manager leak sensor detected a leak.

2. Locate the source of the leak, and make the repairs necessary to stop the leak.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid scratching or damaging the leak sensor:• do not allow buffered solvents to accumulate and dry on it.• do not submerge it in a cleaning bath.

26

Page 27: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

Tip: If the leak sensor cannot be easily manipulated after being removed from its reservoir, detach the connector from the front of the instrument (see page 1-49).

4. Use a nonabrasive, lint-free wipe to dry the leak sensor prism.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

TP02891

Prism

Lint-free wipe

27

Page 28: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

5. Roll up a nonabrasive, lint-free wipe, and use it to absorb the liquid from the leak sensor reservoir and its surrounding area.

6. With a cotton swab, absorb any remaining liquid from the corners of the leak sensor reservoir and its surrounding area.

Rolled up lint-free wipe

Leak sensor reservoir

Cotton swab

Leak sensor reservoir

28

Page 29: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

7. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

TP02919

TP02892

Slot in leak sensor reservoir

T-bar

Leak sensor installed in reservoir

29

Page 30: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

8. Ensure the ribbon cable is routed behind the cable clip.

9. In the ACQUITY UPLC Console, select Column Manager from the system tree.

10. In the column manager information window, click Control > Reset CM to reset the column manager.

Cable clip

Ribbon cable

30

Page 31: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Resolving detector leak sensor errorsAfter approximately 1.5 mL of liquid accumulates in the detector’s leak sensor reservoir, an alarm sounds, indicating that the leak sensor detected a leak.

Required materials

• Chemical-resistant, powder-free gloves• Cotton swabs• Nonabrasive, lint-free wipes

To resolve a detector leak sensor error:

1. View the Leak Sensors dialog box in the ACQUITY UPLC Console to confirm that the detector leak sensor detected a leak.Tip: If a leak was detected, a “Leak Detected” error message appears.

2. Open the detector door, gently pulling its right edge toward you.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Caution: To avoid scratching or damaging the leak sensor:• do not allow buffered solvents to accumulate and dry on it.• do not submerge it in a cleaning bath.

31

Page 32: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Locate the source of the leak, and make the repairs necessary to stop the leak.

4. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

Tip: If the leak sensor cannot be easily manipulated after being removed from its reservoir, detach the connector from the front of the instrument (see page 1-53).

5. Use a nonabrasive, lint-free wipe to dry the leak sensor prism.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

TP02891

Prism

Lint-free wipe

32

Page 33: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

6. Roll up a nonabrasive, lint-free wipe, and use it to absorb the liquid from the leak sensor reservoir and its surrounding area.

7. With a cotton swab, absorb any remaining liquid from the corners of the leak sensor reservoir and its surrounding area.

Rolled up lint-free wipe

Leak sensor reservoir

Cotton swab

Leak sensor reservoir

33

Page 34: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

8. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

9. In the ACQUITY UPLC Console, select your detector from the system tree.

10. In the detector information window, click Control > Reset to reset the detector.

TP02908

TP02892

Slot in leak sensor reservoir

T-bar

Leak sensor installed in reservoir

34

Page 35: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Replacing the binary solvent manager’s leak sensor

Required materials

• New leak sensor• Chemical-resistant, powder-free gloves

To replace the binary solvent manager’s leak sensor:

1. Open the binary solvent manager’s door, gently pulling its right edge toward you.

2. Detach the leak sensor connector from the front of the instrument.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Leak sensor connector

Press down on tab to release connector

35

Page 36: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Turn the vent tube retainer to the right, and then lift the A-vent and B-vent tubes out of the drip tray by pulling upward on them and moving them to the left of the leak sensor.

4. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

5. Unpack the new leak sensor, removing it from its packing material.

TP02884

Turn vent tube retainer to right

Pull up on vent tubes and move them to the left

Leak sensor

Serrations

36

Page 37: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

6. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

7. Reinsert the A-vent and B-vent tubes into the drip tray.

TP02892

TP02888

TP02889

Slot in leak sensor reservoir

Leak sensor installed in reservoir

T-bar

37

Page 38: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

8. Turn the vent tube retainer, which holds the A-vent and B-vent tubing in place, to the left.

9. Connect the leak sensor connector to the front of the instrument.

10. In the ACQUITY UPLC Console, select Binary Solvent Manager from the system tree.

11. In the binary solvent manager information window, click Control > Reset BSM to reset the binary solvent manager.

TP02884

Vent tube retainer

Vent tubes

Leak sensor

38

Page 39: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Replacing the sample manager’s leak sensor

Required materials

• New leak sensor• Chemical-resistant, powder-free gloves

To replace the sample manager’s leak sensor:

1. Open the sample manager door, gently pulling its right edge toward you.

2. Detach the leak sensor connector from the front of the instrument.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Leak sensor connector

Press down on tab to release connector

39

Page 40: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

4. Unpack the new leak sensor, removing it from its packing material.

Serrations

40

Page 41: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

5. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

6. Plug the leak sensor connector into the front of the instrument.

7. In the ACQUITY UPLC Console, select Sample Manager from the system tree.

8. In the sample manager information window, click Control > Reset SM to reset the sample manager.

TP02907

TP02892

T-bar

Leak sensor installed in reservoir

Slot in leak sensor reservoir

41

Page 42: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Replacing the column heater’s leak sensor

Required materials

• New leak sensor• Chemical-resistant, powder-free gloves

To replace the column heater’s leak sensor:

1. Open the sample manager door, gently pulling its right edge toward you.

2. Detach the leak sensor connector from the front of the instrument.

3. Open the column heater door.

4. Remove any solvent lines routed between the column heater door and hinge.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Leak sensor connector

Press down on tab to release connector

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Page 43: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

5. Push down on the metal clip at the bottom, left-hand side of the column heater to release the door, and then pull the door toward you.

6. Swing the door fully to the right.

TP02596

Metal clip

Column heater door

Column heater door

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Page 44: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

7. Remove the leak sensor from its reservoir by grasping it by its serrations, pulling upward on it, and tilting it to the left.

8. Unpack the new leak sensor, removing it from its packing material.

Serrations

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Page 45: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

9. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

10. Plug the leak sensor connector into the front of the instrument.

11. In the ACQUITY UPLC Console, select Sample Manager from the system tree.

12. In the sample manager information window, click Control > Reset SM to reset the sample manager.

TP02909

TP02892

Slot in leak sensor reservoir

T-bar

Leak sensor installed in reservoir

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Page 46: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Replacing the column heater’s leak sensor (door fully opened)

Required materials

• New leak sensor• Chemical-resistant, powder-free gloves

To replace the leak sensor for a column heater with its door fully open:

1. Open the sample manager door, gently pulling its right edge toward you.

2. Detach the leak sensor connector from the front of the instrument.

3. Slide out the sample manager fluidics tray.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Leak sensor connector

Press down on tab to release connector

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Page 47: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

4. Using one finger from each hand, remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

5. Tilt the leak sensor to the right and remove it from under the drip tray.

6. Unpack the new leak sensor, removing it from its packing material.

Caution: To avoid damaging the leak sensor, do not grasp it by the ribbon cable.

Serrations

Leak sensor tilted to right

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Page 48: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

7. Using one finger from each hand, align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

8. Plug the leak sensor connector into the front of the instrument.

9. Slide the fluidics tray closed.

10. In the ACQUITY UPLC Console, select Sample Manager from the system tree.

11. In the sample manager information window, click Control > Reset SM to reset the sample manager.

T-bar

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Page 49: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Replacing the column manager’s leak sensor

Required materials

• New leak sensor• Chemical-resistant, powder-free gloves

To replace the column manager’s leak sensor:

1. Detach the leak sensor connector from the front of the instrument.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Leak sensor connector

Press down on tab to release connector

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Page 50: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

2. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

3. Unpack the new leak sensor, removing it from its packing material.

Serrations

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Page 51: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

4. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

TP02919

TP02892

Slot in leak sensor reservoir

T-bar

Leak sensor installed in reservoir

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Page 52: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

5. Ensure the ribbon cable is routed behind the cable clip.

6. Plug the leak sensor connector into the front of the instrument.

7. In the ACQUITY UPLC Console, select Column Manager from the system tree.

8. In the column manager information window, click Control > Reset CM to reset the column manager.

Cable clip

Ribbon cable

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Page 53: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

Replacing the detector’s leak sensor

Required materials

• New leak sensor• Chemical-resistant, powder-free gloves

To replace the detector leak sensor:

1. Open the detector door, gently pulling its right edge toward you.

2. Detach the leak sensor connector from the front of the instrument.

Warning: The leak sensor can be contaminated with biohazardous and/or toxic materials. Always wear chemical-resistant, powder-free gloves when performing this procedure.

Leak sensor connector

Press down on tab to release connector

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Page 54: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

3. Remove the leak sensor from its reservoir by grasping it by its serrations and pulling upward on it.

4. Unpack the new leak sensor, removing it from its packing material.

Serrations

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Page 55: Leak Sensor Maintenance Instructions7 5. Remove the leak sensor from its reserv oir by grasping it by its serrations and pulling upward on it. Tip: If the leak sensor cannot be easi

5. Align the leak sensor’s T-bar with the slot in the side of the leak sensor reservoir, and slide the leak sensor into place.

6. Plug the leak sensor connector into the front of the instrument.

7. In the ACQUITY UPLC Console, select your detector from the system tree.

8. In the detector information window, click Control > Reset to reset the detector.

TP02908

TP02892

Slot in leak sensor reservoir

T-bar

Leak sensor installed in reservoir

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