LENVIMA® is a registered trademark used by Eisai Inc. under license from Eisai R&D Management Co., Ltd.© 2017 Eisai Inc. All rights reserved.Printed in USA/February 2018 LENV-US0459(1)a

Accessing LENVIMA® and Enhanced Patient Support with the LENVIMA Intake Form

Please visit www.LENVIMA.com/hcp or speak with your Eisai Sales Representative to obtain additional copies of the LENVIMA Intake Form.

Please visit www.LenvimaReimbursement.com/hcpfor more information about access and reimbursement.

LENVIMA®(lenvatinib) capsulesDistribution and fi nancial assistance information

Enhanced Patient SupportThe Enhanced Patient Support program for LENVIMA providesa number of services to help patients throughout the treatmentjourney. Patients receiving LENVIMA from Accredo or Biologicswill be automatically enrolled in these services upon consent, whereas patients receiving LENVIMA from another source may be enrolled via the LENVIMA Intake Form or by calling the Eisai Assistance Program at 1-866-61-EISAI (1-866-613-4724).

Enhanced Patient Support includes

comprehensive benefi t investigation* to help patients understand their coverage for LENVIMA

a patient starter kit that includes key LENVIMA educational materials and helpful resources for patients receiving therapy

ongoing patient communications for monitoring patient progress,adverse reaction management, and questions about LENVIMA therapy

* Reimbursement assistance for patients receivingLENVIMA from a source other than Accredo or Biologics will be provided by the Eisai Assistance Program. Please call 1-866-61-EISAI (1-866-613-4724) for more information.

The Eisai Assistance Program is your resource for information about your patients’ benefi ts for LENVIMA and available fi nancial assistance options. Our specialists will complete a full benefi t investigation to understand your patients’ insurance coverage for LENVIMA. If needed, our specialists can also discuss options for fi nancial assistance to help your patients access LENVIMA.

Contact informationPhone: 1-866-61-EISAI (1-866-613-4724)

Fax: 1-855-246-5192

Hours: 9 AM to 6 PM ET, Monday through Friday

www.LenvimaReimbursement.com/hcp

Eisai cannot guarantee payment of any claim. Coding, coverage, and reimbursement may vary signifi cantly by payer, plan, patient, and setting of care. Actual coverage and reimbursement decisions are made by individual payers following the receipt of claims. For additional information, customers should consult with their payers for all relevant coding, reimbursement, and coverage requirements. It is the sole responsibility of the provider to select the proper code and ensure the accuracy of all claims used in seeking reimbursement. All services must be medically appropriate and properly supported in the patient medical record.

Reimbursement assistance for LENVIMA

The LENVIMA $0 Co-pay Program o� ers commercially insured patients a $0 co-pay on each prescription, with a $40,000 annual limit.*

Alternate funding assistance may also be available for those who are not eligible for the LENVIMA $0 Co-pay Program.

* Maximum benefi t: The LENVIMA $0 Co-pay Program provides up to $40,000 per year to assist with the out-of-pocket costs for LENVIMA. Depending on the insurance plan, patients could have additional fi nancial responsibility for any amounts over Eisai’s maximum liability.Eligibility criteria: Good toward the purchase of LENVIMA prescriptions. No substitutions permitted. Not available to patients eligible for state or federal healthcare programs, including Medicare, Medicaid, Medigap, VA, DoD, or TRICARE. O� er only available to patients with private, commercial insurance. O� er available to MA residents through June 30, 2019. May not be combined with any other coupon, discount, prescription savings card, free trial, or other o� er. Eisai Inc. reserves the right to rescind, revoke, or amend this o� er at any time without notice. Patients and pharmacies are responsible for disclosing to insurance carriers the redemption and value of the program and complying with any other conditions imposed by insurance carriers on third-party payers. The value of this program is not contingent on any prior or future purchases. This program is solely intended to provide savings on a purchase of LENVIMA. Use of this program for any one purchase does not obligate the patient to make future purchases of LENVIMA or any other product. This o� er will expire March 31, 2020.

LENVIMA $0 Co-pay Program

How to start your patients on LENVIMALENVIMA is available through 2 Specialty Pharmacies, Accredo and Biologics, that will mail LENVIMA directly to your patients. To fi ll a prescription through Accredo or Biologics, please use the LENVIMA Intake Form found at www.LENVIMA.com/hcp or delivered by your Eisai Sales Representative.

Phone: 1-844-693-0156

Fax: 1-877-247-4847

www.accredo.com

Phone: 1-800-850-4306

Fax: 1-800-823-4506

www.biologicsinc.com

Please contact your preferred distributor for more information, including eligibility requirements.

Accessing LENVIMA®

Physician o� ce/clinic or hospital pharmaciesLENVIMA has expanded its distribution network to allow for dispensing through select in-o� ce and hospital-based pharmacies.

Eisai Patient Assistance ProgramEisai has established the Patient Assistance Program for patients who need help paying for LENVIMA. This program provides LENVIMA at no cost to uninsured and fi nancially burdened patients who meet the program eligibility criteria.

LENVIMA® is a registered trademark used by Eisai Inc. under license from Eisai R&D Management Co., Ltd.© 2017 Eisai Inc. All rights reserved.Printed in USA/February 2018 LENV-US0459(1)a

Accessing LENVIMA® and Enhanced Patient Support with the LENVIMA Intake Form

Please visit www.LENVIMA.com/hcp or speak with your Eisai Sales Representative to obtain additional copies of the LENVIMA Intake Form.

Please visit www.LenvimaReimbursement.com/hcpfor more information about access and reimbursement.

LENVIMA®(lenvatinib) capsulesDistribution and fi nancial assistance information

Enhanced Patient SupportThe Enhanced Patient Support program for LENVIMA providesa number of services to help patients throughout the treatmentjourney. Patients receiving LENVIMA from Accredo or Biologicswill be automatically enrolled in these services upon consent, whereas patients receiving LENVIMA from another source may be enrolled via the LENVIMA Intake Form or by calling the Eisai Assistance Program at 1-866-61-EISAI (1-866-613-4724).

Enhanced Patient Support includes

comprehensive benefi t investigation* to help patients understand their coverage for LENVIMA

a patient starter kit that includes key LENVIMA educational materials and helpful resources for patients receiving therapy

ongoing patient communications for monitoring patient progress,adverse reaction management, and questions about LENVIMA therapy

* Reimbursement assistance for patients receivingLENVIMA from a source other than Accredo or Biologics will be provided by the Eisai Assistance Program. Please call 1-866-61-EISAI (1-866-613-4724) for more information.

The Eisai Assistance Program is your resource for information about your patients’ benefi ts for LENVIMA and available fi nancial assistance options. Our specialists will complete a full benefi t investigation to understand your patients’ insurance coverage for LENVIMA. If needed, our specialists can also discuss options for fi nancial assistance to help your patients access LENVIMA.

Contact informationPhone: 1-866-61-EISAI (1-866-613-4724)

Fax: 1-855-246-5192

Hours: 9 AM to 6 PM ET, Monday through Friday

www.LenvimaReimbursement.com/hcp

Eisai cannot guarantee payment of any claim. Coding, coverage, and reimbursement may vary signifi cantly by payer, plan, patient, and setting of care. Actual coverage and reimbursement decisions are made by individual payers following the receipt of claims. For additional information, customers should consult with their payers for all relevant coding, reimbursement, and coverage requirements. It is the sole responsibility of the provider to select the proper code and ensure the accuracy of all claims used in seeking reimbursement. All services must be medically appropriate and properly supported in the patient medical record.

Reimbursement assistance for LENVIMA

The LENVIMA $0 Co-pay Program o� ers commercially insured patients a $0 co-pay on each prescription, with a $40,000 annual limit.*

Alternate funding assistance may also be available for those who are not eligible for the LENVIMA $0 Co-pay Program.

* Maximum benefi t: The LENVIMA $0 Co-pay Program provides up to $40,000 per year to assist with the out-of-pocket costs for LENVIMA. Depending on the insurance plan, patients could have additional fi nancial responsibility for any amounts over Eisai’s maximum liability.Eligibility criteria: Good toward the purchase of LENVIMA prescriptions. No substitutions permitted. Not available to patients eligible for state or federal healthcare programs, including Medicare, Medicaid, Medigap, VA, DoD, or TRICARE. O� er only available to patients with private, commercial insurance. O� er available to MA residents through June 30, 2019. May not be combined with any other coupon, discount, prescription savings card, free trial, or other o� er. Eisai Inc. reserves the right to rescind, revoke, or amend this o� er at any time without notice. Patients and pharmacies are responsible for disclosing to insurance carriers the redemption and value of the program and complying with any other conditions imposed by insurance carriers on third-party payers. The value of this program is not contingent on any prior or future purchases. This program is solely intended to provide savings on a purchase of LENVIMA. Use of this program for any one purchase does not obligate the patient to make future purchases of LENVIMA or any other product. This o� er will expire March 31, 2020.

LENVIMA $0 Co-pay Program

How to start your patients on LENVIMALENVIMA is available through 2 Specialty Pharmacies, Accredo and Biologics, that will mail LENVIMA directly to your patients. To fi ll a prescription through Accredo or Biologics, please use the LENVIMA Intake Form found at www.LENVIMA.com/hcp or delivered by your Eisai Sales Representative.

Phone: 1-844-693-0156

Fax: 1-877-247-4847

www.accredo.com

Phone: 1-800-850-4306

Fax: 1-800-823-4506

www.biologicsinc.com

Please contact your preferred distributor for more information, including eligibility requirements.

Accessing LENVIMA®

Physician o� ce/clinic or hospital pharmaciesLENVIMA has expanded its distribution network to allow for dispensing through select in-o� ce and hospital-based pharmacies.

Eisai Patient Assistance ProgramEisai has established the Patient Assistance Program for patients who need help paying for LENVIMA. This program provides LENVIMA at no cost to uninsured and fi nancially burdened patients who meet the program eligibility criteria.

The Eisai Assistance Program is your resource for information about your patients’ benefi ts for LENVIMA and available fi nancial assistance options. Our specialists will complete a full benefi t investigation to understand your patients’ insurance coverage for LENVIMA. If needed, our specialists can also discuss options for fi nancial assistance to help your patients access LENVIMA.

Contact informationPhone: 1-866-61-EISAI (1-866-613-4724)

Fax: 1-855-246-5192

Hours: 9 AM to 6 PM ET, Monday through Friday

www.LenvimaReimbursement.com/hcp

Eisai cannot guarantee payment of any claim. Coding, coverage, and reimbursement may vary signifi cantly by payer, plan, patient, and setting of care. Actual coverage and reimbursement decisions are made by individual payers following the receipt of claims. For additional information, customers should consult with their payers for all relevant coding, reimbursement, and coverage requirements. It is the sole responsibility of the provider to select the proper code and ensure the accuracy of all claims used in seeking reimbursement. All services must be medically appropriate and properly supported in the patient medical record.

Reimbursement assistance for LENVIMA

The LENVIMA $0 Co-pay Program o� ers commercially insured patients a $0 co-pay on each prescription, with a $40,000 annual limit.*

Alternate funding assistance may also be available for those who are not eligible for the LENVIMA $0 Co-pay Program.

* Maximum benefi t: The LENVIMA $0 Co-pay Program provides up to $40,000 per year to assist with the out-of-pocket costs for LENVIMA. Depending on the insurance plan, patients could have additional fi nancial responsibility for any amounts over Eisai’s maximum liability.Eligibility criteria: Good toward the purchase of LENVIMA prescriptions. No substitutions permitted. Not available to patients eligible for state or federal healthcare programs, including Medicare, Medicaid, Medigap, VA, DoD, or TRICARE. O� er only available to patients with private, commercial insurance. O� er available to MA residents through June 30, 2019. May not be combined with any other coupon, discount, prescription savings card, free trial, or other o� er. Eisai Inc. reserves the right to rescind, revoke, or amend this o� er at any time without notice. Patients and pharmacies are responsible for disclosing to insurance carriers the redemption and value of the program and complying with any other conditions imposed by insurance carriers on third-party payers. The value of this program is not contingent on any prior or future purchases. This program is solely intended to provide savings on a purchase of LENVIMA. Use of this program for any one purchase does not obligate the patient to make future purchases of LENVIMA or any other product. This o� er will expire March 31, 2020.

LENVIMA $0 Co-pay Program

How to start your patients on LENVIMALENVIMA is available through 2 Specialty Pharmacies, Accredo and Biologics, that will mail LENVIMA directly to your patients. To fi ll a prescription through Accredo or Biologics, please use the LENVIMA Intake Form found at www.LENVIMA.com/hcp or delivered by your Eisai Sales Representative.

Phone: 1-844-693-0156

Fax: 1-877-247-4847

www.accredo.com

Phone: 1-800-850-4306

Fax: 1-800-823-4506

www.biologicsinc.com

Please contact your preferred distributor for more information, including eligibility requirements.

Accessing LENVIMA®

Physician o� ce/clinic or hospital pharmaciesLENVIMA has expanded its distribution network to allow for dispensing through select in-o� ce and hospital-based pharmacies.

Eisai Patient Assistance ProgramEisai has established the Patient Assistance Program for patients who need help paying for LENVIMA. This program provides LENVIMA at no cost to uninsured and fi nancially burdened patients who meet the program eligibility criteria.