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Design and Synthesis of Novel Nucleobase-based Barbiturate Derivatives as Potential Anticancer Agents Bhaveshkumar D. Dhorajiya a , Ahmed S Ibrahim b , Farid A. Badria c and Bharatkumar Z. Dholakiya a * a Department of Applied Chemistry, S.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt c Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt. * Corresponding authors. Tel: +91-9428949595, Fax No: +91-0261- 227334 E- mail address: [email protected],[email protected] , (1) FT-IR Spectrum Of Compound (BA) Supplementary

link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

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Page 1: link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

Design and Synthesis of Novel Nucleobase-based Barbiturate

Derivatives as Potential Anticancer AgentsBhaveshkumar D. Dhorajiyaa, Ahmed S Ibrahimb, Farid A. Badriac and Bharatkumar Z.

Dholakiyaa*a Department of Applied Chemistry, S.V. National Institute of Technology, Ichchhanath, surat-

395007, Gujarat, India.b Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516,

EgyptcDepartment of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.*Corresponding authors. Tel: +91-9428949595, Fax No: +91-0261-227334

E- mail address: [email protected],[email protected]

(1) FT-IR Spectrum Of Compound (BA)

(2)FT-IR Spectrum Of Compound (1,3-BA)

Supplementary

Page 2: link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

(3) FT-IR Spectrum of Compound (BAMT)

(1) 1H-NMR-Spectrum of compound (BA)

Page 3: link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

(5) 1H-NMR Spectrum of Compound (1, 3-BA)

(6)13C-NMR Spectrum of Compound (1, 3-BA)

Page 4: link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

(7)HMBC- Spectrum of Compound (1, 3-BA)

(8)1H-NMR Spectrum of Compound (BAMT)

Page 5: link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

(9)13C-NMR Spectrum of Compound (BAMT)

(10) HMBC-Spectrum of Compound (BAMT)

Page 6: link.springer.com · Web viewS.V. National Institute of Technology, Ichchhanath, surat-395007, Gujarat, India. b Department of Biochemistry, Faculty of Pharmacy, Mansoura University,

(11) ESI-MASS Spectrum of Compound (BAMT)