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2004 Pyrazine derivatives
Pyrazine derivativesR 0550 Lithiation and Side-Chain Substitution of 3-Alkyl-1H-quinoxalin-2-ones. —
Dilithiation of 1H-quinoxalin-2-ones and trapping of the resulting dilithio reagent with various electrophiles side-chain substituted products exclusively. Iodine as the electro-phile leads to product (VI) of oxidative dimerization. — (SMITH*, K.; EL-HITI, G. A.; MAHGOUB, S. A.; Synthesis 2003, 15, 2345-2348; Cent. Clean Chem., Univ. Wales, Swansea SA2 8PP, UK; Eng.) — Mais
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