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Lower Gastrointestinal Tract
KNH 411
© 2007 Thomson - Wadsworth
Pathophysiology: Lower GI Tract
●Malabsorption - maldigestion of fat, CHO, Protein
● Decreased villious height, enzyme production
● Decreased transit time
Pathophysiology: Lower GI Tract
●Malabsorption - fat● Steatorrhea
● Fat-soluble vitamins malabsorbed
● Potential for excess oxalate
● Abdominal pain, cramping, diarrhea
● Dg; fecal fat test or D-xylose absorption test, or small bowel x-ray
Pathophysiology: Lower GI Tract
●Malabsorption - Fat – Nutrition
● Restrict fat 25-50 g/day
● Use of MCT supplements
● Pancreatic enzymes
Pathophysiology: Lower GI Tract
●Malabsorption - CHO● Lactose malabsorption
● Most common
● Lactade
● Increased gas, abdominal cramping, diarrhea
● Restrict milk and dairy products
● Products such as Lactaid can be rec.
Pathophysiology: Lower GI Tract
●Malabsorption - protein● Protein-losing enteropathy
● Reduced serum protein● Due to excess loss of protein in stool
● Peripheral edema ● Due to oncotic pressure
● Korshikor & marasmus
● Diseases left untreated
Pathophysiology: Lower GI Tract
●Malabsorption - Nutrition Therapy● Results in weight loss
● Treat underlying disease/ nutrient being malabsorbed
Pathophysiology: Lower GI Tract
●Celiac disease
● Genetic and autoimmune
● Occurs when alpha-gliadin from wheat, rye, malt, barley are eaten
● Infiltration of WBC, production of IgA antibodies
Pathophysiology: Lower GI Tract
●Celiac disease - pathophysiology● Damage to villi
● Decreased enzyme function
● Maldigestion and malabsorption
● Occurs with other autoimmune disorders
Pathophysiology: Lower GI Tract
●Celiac disease - clinical manifestations
● Diarrhea, abdominal pain, cramping, bloating, gas
● Muscle cramping, fatigue
● Skin rash
● Higher risk for lymphoma and osteoporosis
Pathophysiology: Lower GI Tract
●Celiac Disease - Diagnosis/Treatment/Prognosis● Biopsy of small intestinal mucosa
● Reversal of symptoms following gluten-free diet
● Refractory CD; d/t coexisting disease
Pathophysiology: Lower GI Tract
●Celiac Disease - Nutrition Intervention● Low-residue, low-fat, lactose-free, gluten-free diet
● Identify hidden sources of gluten
● Specialty products
Pathophysiology: Lower GI Tract
●Irritable Bowel Syndrome (IBS)
● Pain relieved with defecation● Onset associated with change in frequency of stool● Onset associated with change in form of stool
●Eliminate “red flag” symptoms● Anemia, weight loss, history of colon cancer
Pathophysiology: Lower GI Tract
●IBS● Most common GI complaint
● Etiology unknown
● Increased serotonin, inflammatory response, abnormal motility, pain
Pathophysiology: Lower GI Tract
●IBS - clinical manifestations● Abdominal pain, alterations in bowel habits, gas,
flatulence
● Increased sensitivity to certain foods
● Concurrent dg
Pathophysiology: Lower GI Tract
●IBS - Treatment● Guided by symptoms● Antidiarrheal agents● Tricyclic antidepressants, SSRIs● Bulking agents, laxatives● Behavioral therapies
● Hypnosis, guided imagery
Pathophysiology: Lower GI Tract
●IBS - Nutrition Therapy● Can lead to nutrient deficiency, underweight,
malnourished, low gas producing foods
● Decrease anxiety, normalize dietary patterns
Pathophysiology: Lower GI Tract
●IBS - Nutrition Therapy● Assess diet hx
● Look for offensive foods
● Assess nutritional adequacy● Focus on increasing fiber intake
● At least 25g of fiber per day ● Slowly increase if their under
● Adequate fluid● Pre- and probiotics
● Build up normal gut flora
● Avoid foods that produce gas ● Simple carbs, lactose, sorbitol, offer agents to help with
gas producing
© 2007 Thomson - Wadsworth
© 2007 Thomson - Wadsworth
Pathophysiology: Lower GI Tract
●IBD - Nutrition Therapy
● Malnutrition● Takes two to three days to make up what you’ve lost
● May need to increase kcal, protein, micronutrients
Pathophysiology: Lower GI Tract
●IBD - Nutrition Interventions● During exacerbation ● Supplement ● Assess energy needs + stress factor● May need to increase protein● Low-residue, lactose-free diet● Small, frequent meals
Pathophysiology: Lower GI Tract
●IBD - Nutrition Interventions● May use MCT oil ● Restrict gas-producing foods● Increase fiber and lactose as tolerated● Advancement of oral diet ● Multivitamin
Pathophysiology: Lower GI Tract
●IBD - Nutrition Interventions● During remission/rehabilitation
● Maximize energy & protein
● Weight gain and physical activity
● Food sources of antioxidants, Omega-3s
● Pro- and prebiotics
Pathophysiology: Lower GI Tract
●Diverticulosis/diverticulitis – abnormal presence of outpockets or pouches on surface of SI or colon/inflammation of these ● Low fiber intake during the inflammation stage
● Increases inflammatory response
● Other risks
Pathophysiology: Lower GI Tract
●Diverticulosis/diverticulitis – pathophysiology● Fecal matter trapped
● Development of pouches
● Diverticulitis ● Food stuff to avoid
● Just a low fiber diet
● Bleeding abscess, obstruction, fistula, perforation
Pathophysiology: Lower GI Tract
●Diverticulosis/-itis – Treatment/ Nutrition Therapy● Specific focus on fiber● Pro- and prebiotic supplementation● Acute ● Antibiotics
● Only used in itis stage, have blood in stool, fever
Pathophysiology: Lower GI Tract
●Diverticulosis/-itis – Nutrition Therapy● -osis ● Avoid nuts, seeds, hulls*
● Current research shows that this isn’t a problem
● Only if client feels its necessary
● Fiber supplement● -itis
● Low fiber diet
● Bowel rest● Avoid nuts, seeds, fibrous vegetables