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Lymphatic, immunity, & blood typing
Chapters 15, 20, and 21
Learning objectives
• Discuss the anatomy and role of the lymphatic system
• Discuss 1st, 2nd, and 3rd line of defenses of the body
• B-cells v T-cells• Various forms of immunity• Tissue Injury• Blood typing
Lymphatic system
• “Clean excess fluid”
• “Return excess fluid”
• Borders blood• Fluid in lymphatic
system?– Lymph
Lymphatic system
• Right lymphatic duct:–Right arm–Right head–Right thorax
• Thoracic duct:–Everything else
• Lymph nodes
Lymphatic system
• Tonsils• Thymus• Spleen
Immunity• Non-specific:• “Fights everything”• First Line– Mechanical
• Skin• Mucous membranes
– Chemical– Protective reflex
Immunity
• Non-specific• 2nd line• Phagocytosis• Inflammation• Fever– Review
thermoregulation
Tissue injury
• Ruptured defense– Pain– Fever– Inflammation– Histamine– WBCs
Colors to skin
• Jaundice— “yellow”
• Cyanosis—Lack of oxygen “blue”
• Flushed—Heated “red”
• White—“cold”
Immunity
• 3rd line• Specific:–“Fights unique
things”• B-cells• T-cells
Immunity
• B-cells–Antibodies–Antigens
• Antibody-mediated• Immune
memory
Immunity
• T-cells–Killer cells
• Cell-mediated
Immunity
• Primary response• Secondary
response• Immunotolerance
Immunity
• Active• Passive• Natural• Artificial
Group activity
Blood typing
• ABO system–A—A antigens–B—B antigens–AB—both A &B
antigens–O—no A or B
antigens
• Rh antigen– + or -
Blood TypingPractice
Rh “sensitization”
• Negative blood exposed to Positive blood– Accident– Pregnancy
• Erythroblastosis fetalis• RhoGam
• Hemolysis
• Agglutination
Group activity