Particularly important group to assess for possible aspirin exacerbated respiratory disease Sinus CT scan to delineate extent of nasal polyps Poor or short-lived response Health National Jewish Polyps in one nasal passage +/- epistaxis or visual change PATIENTS WITH NASAL POLYPS Assess disease burden Provide an urgent referral to ENT Polyps in both nasal passages and mild symptoms Administer intranasal glucocorticoid spray and saline irrigation; encourage adherence to therapy Polyps in both nasal passages and moderate to severe symptoms Administer intranasal glucocorticoid and saline irrigation; consider oral glucocorticoids MANAGEMENT OF CHRONIC RHINOSINUSITIS WITH NASAL POLYPS Improved symptom burden Consider a personalized approach for persistent moderate-to-severe symptoms • Continue intranasal glucocorticoid spray and saline irrigations • Encourage adherence to therapy Treatment options include: • Endoscopic sinus surgery • Trial of biologic agent (dupilumab or omalizumab) • Reserve repeated systemic glucocorticoids when possible given side effects • Continue topical/intranasal glucocorticoids Adapted from: Hopkins C. Chronic Rhinosinusitis With Nasal Polyps N Engl J Med 2019; 381: 55-63. Orlandi RR, et al. International Consensus Statement on Rhinology and Allergy: Rhinosinusitis. Int Forum Allergy Rhinol. 2020 Nov 24. doi: 10.1002/alr.22741. Epub ahead of print. PMID: 33236525.

MANAGEMENT OF CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

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Page 1: MANAGEMENT OF CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

Particularly importantgroup to assess for possibleaspirin exacerbatedrespiratory disease

Sinus CT scanto delineate extent

of nasal polyps

Poor or short-lived response

HealthNational Jewish

Polyps in one nasal passage +/- epistaxis or visual change

PATIENTS WITH NASAL POLYPSAssess disease burden Provide an

urgent referralto ENT

Polyps in both nasal passages and mild symptoms

Administer intranasal glucocorticoid spray and saline irrigation; encourage adherence to therapy

Polyps in both nasal passages and moderate to severe symptoms

Administer intranasal glucocorticoid andsaline irrigation; consider oral glucocorticoids

MANAGEMENT OF CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

Improved symptom burden

Consider a personalizedapproach for persistent

moderate-to-severe symptoms• Continue intranasal glucocorticoid spray and saline irrigations• Encourage adherence to therapy

Treatment options include: • Endoscopic sinus surgery• Trial of biologic agent (dupilumab or omalizumab)• Reserve repeated systemic glucocorticoids when possible given side effects• Continue topical/intranasal glucocorticoids

Adapted from: Hopkins C. Chronic Rhinosinusitis With Nasal Polyps N Engl J Med 2019; 381: 55-63.

Orlandi RR, et al. International Consensus Statement on Rhinology and Allergy: Rhinosinusitis. Int Forum Allergy Rhinol. 2020 Nov 24. doi: 10.1002/alr.22741. Epub ahead of print. PMID: 33236525.