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March 15, 2020 BY HAND DELIVERY/RPAD To, The Director IA (Industry-II) Ministry of Environment, Forest and Climate Change Government of India, Indira Paryavarn Bhavan, Aliganj, Jor Bagh Road, New Delhi – 110 003 SUB: ADDITIONAL INFORMATION FOR ENVIRONMENTAL CLEARANCE PROPOSED BULK DRUG AND BULK DRUGS INTERMEDIATES AT M/S. VARDA LIFE SCIENCE LLP, PLOT NO. 3202/A/2,GIDC INDUSTRIAL ESTATE, ANKLESHWAR, DIST: BHARUCH-393002 (GUJARAT) CATEGORY: A-5(f): UNIT LOCATED IN GIDC INDUSTRIAL ESTATE (INDUSTRIAL SECTOR PROJECT) AS MENTIONED ABOVE PROPOSED PROJECT FALL UNDER CATEGORY B1 AND SAME WILL BE TREATED AS CATEGORY-A AS PER BELOW MENTIONED REFERENCE. REF: EIA NOTIFICATION OF MOEF DATED SEPT. 14, 2006 CONSIDERING OM ISSUED BY CPCB VIDE ORDER NO CPCB/IPC- VII/CEPI/NGT/2019 ON DATED:-25/10/2019 GENERAL CONDITION WILL BE APPLICABLE TO OUR UNIT. [I.E. PROJECTS FALL UNDER CATEGORY B1 WILL BE TREATED AS CATEGORY A, OUR PROJECT IS LOCATED AT ANKLESHWAR, DIST:- BHARUCH AND ANKLESHWAR IS DECLARED AS CRITICALLY POLLUTED AREA] Dear Sir, This has reference to above mentioned subject matter. We are submitting herewith Additional Information Report including EIA Report (1 hard copy + 1 CD) to obtain environmental clearance for Proposed Bulk Drug And Bulk Drugs Intermediates At M/s. Varda Life Science LLP, Plot No. 3202/A/2,GIDC Industrial Estate, Ankleshwar, Dist: Bharuch-393002 (Gujarat) [Industrial Sector Project-Category: A-5 (f)]. We hope you would find the same in order and request your kind self to grant us environmental clearance and oblige. Thanking you. Yours faithfully, M/s. Varda Life Science

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March 15, 2020 BY HAND DELIVERY/RPAD To, The Director IA (Industry-II) Ministry of Environment, Forest and Climate Change Government of India, Indira Paryavarn Bhavan, Aliganj, Jor Bagh Road, New Delhi – 110 003

SUB: ADDITIONAL INFORMATION FOR ENVIRONMENTAL CLEARANCE PROPOSED BULK DRUG AND BULK DRUGS INTERMEDIATES AT M/S. VARDA LIFE SCIENCE LLP, PLOT NO. 3202/A/2,GIDC INDUSTRIAL ESTATE, ANKLESHWAR, DIST: BHARUCH-393002 (GUJARAT)

CATEGORY: A-5(f): UNIT LOCATED IN GIDC INDUSTRIAL ESTATE (INDUSTRIAL SECTOR PROJECT)

AS MENTIONED ABOVE PROPOSED PROJECT FALL UNDER CATEGORY B1 AND SAME WILL BE TREATED AS CATEGORY-A AS PER BELOW MENTIONED REFERENCE.

REF: EIA NOTIFICATION OF MOEF DATED SEPT. 14, 2006 CONSIDERING OM ISSUED BY CPCB VIDE ORDER NO CPCB/IPC-VII/CEPI/NGT/2019 ON DATED:-25/10/2019 GENERAL CONDITION WILL BE APPLICABLE TO OUR UNIT. [I.E. PROJECTS FALL UNDER CATEGORY B1 WILL BE TREATED AS CATEGORY A, OUR PROJECT IS LOCATED AT ANKLESHWAR, DIST:- BHARUCH AND ANKLESHWAR IS DECLARED AS CRITICALLY POLLUTED AREA]

Dear Sir, This has reference to above mentioned subject matter. We are submitting herewith Additional Information Report including EIA Report (1 hard copy + 1 CD) to obtain environmental clearance for Proposed Bulk Drug And Bulk Drugs Intermediates At M/s. Varda Life Science LLP, Plot No. 3202/A/2,GIDC Industrial Estate, Ankleshwar, Dist: Bharuch-393002 (Gujarat) [Industrial Sector Project-Category: A-5 (f)]. We hope you would find the same in order and request your kind self to grant us environmental clearance and oblige. Thanking you. Yours faithfully,

M/s. Varda Life Science

(i) TOR granted by SEEIA however, now application submitted at Central level please clarify (ii) All old CTOs not uploaded to verify the violation, if any done by PP. (iii) TOR compliance is not adequate in EIA/EMP report and need to revise as per the terms of reference granted for the project, and shall conform to Appendix III of the EIA Notification, 2006. (iv) Submit action plan as per the Ministry’s office memorandum 31st October, 2019 regarding projects located in Critically Polluted Area. (v) Effluent treatment mechanism with plan for Zero Liquid Discharge needs to be submitted. (vi) Details of Raw material linkage (S. no. 13.1 of form 2) and its mitigation measure during transportation needs to be submitted. (vii) Proposed Green belt development programe along-with time line and budgetary allocation needs to be provided(green belt has not mentioned as per OM Dated 31.10.2019-CPA) (viii) Details of Court case if any. (ix) Updated status of water approval. (x) In view of the above, PP/Consultant are requested to revise the application for grant of EC and accordingly revise the Form 2 alongwith EIA/EMP Report. The EIA/EMP Report shall match with the information as filled in Form 2. On examination it is observed that the Consultant has not adequately submitted the application as per the provisions of the EIA Notification, 2006. Consultant has to read the documents before uploading the information in Form 2 /EIA/EMP report.

(i) TOR granted by SEEIA however, now application submitted at Central level please clarify.

As Per Om Issued By CPCB Vide Order No CPCB/IPC-VII/CEPI/NGT/2019 On Dated:-25/10/2019 General Condition Will Be Applicable To Our Unit. [I.E. Projects Fall Under Category B1 Will Be Treated As Category A, Our Project Is Located At Ankleshwar, Dist:- Bharuch And Ankleshwar Is Declared As Critically Polluted Area]. So we have applied for EC at Central Level. (ii) All old CTOs not uploaded to verify the violation, if any done by PP. This is a Greenfield Project. So, we have not CTO. (iii) TOR compliance is not adequate in EIA/EMP report and need to revise as per the

terms of reference granted for the project, and shall conform to Appendix III of the EIA Notification, 2006.

EIA Report is revised and TOR compliance is adequately prepared. Revised EIA Report with adequate TOR Compliance is uploaded with Form-2 is attached with Additional Information file. (iv) Submit action plan as per the Ministry’s office memorandum 31st October, 2019

regarding projects located in Critically Polluted Area. Action plan in view of the project site being in Critically Polluted Area

Sr. No.

Environment Mitigation Measures Measures to be taken

1. Air (i) Stack emission levels should be stringent than the existing standards in terms of the identified critical pollutants

Adequate stack height of 30 m will be provided with Boiler & TFH and stack emission levels will be stringent than the existing standards as prescribed by CPCB.

(ii) CEMS may be installed in all large/ medium red category industries (air polluting) and connected to SPCB and CPCB server.

Not Applicable. Unit is Proposed Natural gas As a Fuel.

(iii) Effective fugitive emission control measures should be imposed in the process, transportation, packing, etc.

Measures to control fugitive emissions. (i) Airborne dust at all transfers operations/ points will be controlled either by spraying water or providing enclosures. (ii) Adequate ventilation will be provided. (iii) Regular maintenance of valves, pumps, flanges, joints and other equipment will be done to prevent leakages and thus minimizing the fugitive emissions of VOCs. (iv) Entire process will be carried out in the closed reactors with proper maintenance of pressure and temperature. (v) Periodic monitoring of work area will be carried out to check the fugitive emission. (vi) To eliminate chances of leakages from glands of pumps, mechanical seal will be

provided at all solvent pumps. (vii) For dust emissions bag filter will be provided. (viii) Dedicated scrubber will be provided are used for fugitive emissions to control. (ix) Regular inspection of floating roof seals and proper preventive maintenance of roofs and seals for tanks. (x) Close feeding system will be provided for centrifuges. Centrifuge and filtrate tank vents will be connected to vent chillers.

(iv) Transportation of material by rail/ conveyor belt, wherever feasible.

Not Applicable, all the local raw material will be transported by road and imported materials will be transported by sea and then the material shall reach the site by road.

(v) Encourage use of cleaner fuels (pet coke/ furnace oil/ LSHS may be avoided).

We will use Natural Gas as fuel in Boiler and TFH and in case of non-availability of Natural Gas, Briquettes of Bio-Coal will be used.

(vi) Best available technology may be used. For example, usage of EAF/ SAF/ IF in place of Cupola furnace. Usage of Supercritical technology in place of sub-critical technology.

(vii) Increase of green belt cover by 40% of the total land area beyond the permissible requirement of 33%, wherever feasible.

Unit has already provided 2631.0 sq. m. i.e. 40.0% of Green belt area within premises.

(viii) Stipulation of green belt outside the project premises such as avenue plantation, plantation in vacant areas, social forestry, etc.

We have planted green belt outside the premises within the periphery of the project site.

(ix) Assessment of carrying capacity of transportation load on roads inside the industrial premises. If the roads required to be widened, shall be prescribed as a condition.

We have well developed 3-4 m width roads for carrying transportation load and there is no requirement of road widening and moreover the site is located within notified industrial area of GIDC having well developed road infrastructure.

2. Water (i) Reuse/ recycle of treated wastewater, wherever feasible.

We Proposed In House MEE plant. Total raw water requirement will be 51.58 KL/day (Fresh: 24.58 KLD + Reuse: 27.0 KLD) (Industrial: 41.58 KL/day + Domestic: 5.0

KL/day + Gardening: 5.0 KL/day) which will be met through GIDC water supply. Total waste water generation will be 38.85 KL/day (Industrial: 34.85 KL/day + Domestic: 4.0 KL/day). Waste Stream (Process, Boiler, Cooling, Washing) 29.85 KLD ETP with primary treatment, and send In-House MEE Plant followed by Solvent Stripper. 27 KLD MEE Condensate will be reuse in plant premises. Scrubbing Media Reuse in plant Premises and Sell to end user. Domestic waste water will be disposed of through septic tank & soak pit.

(ii) Continuous monitoring of effluent quality/ quantity in large and medium Red Category Industries (water polluting).

We have installed pH meter & flow meter for Continuous monitoring of effluent quality/ quantity in our plant and is connected to SPCB and CPCB server.

(iii) A detailed water harvesting plan may be submitted by the project proponent.

Not Applicable. Proposed unit is synthetic organic Chemical unit.

(iv) Zero Liquid discharge wherever techno-economically feasible.

We Proposed In House MEE plant. Total raw water requirement will be 51.58 KL/day (Fresh: 24.58 KLD + Reuse: 27.0 KLD) (Industrial: 41.58 KL/day + Domestic: 5.0 KL/day + Gardening: 5.0 KL/day) which will be met through GIDC water supply. Total waste water generation will be 38.85 KL/day (Industrial: 34.85 KL/day + Domestic: 4.0 KL/day). Waste Stream (Process, Boiler, Cooling, Washing) 29.85 KLD ETP with primary treatment, and send In-House MEE Plant followed by Solvent Stripper. 27 KLD MEE Condensate will be reuse in plant premises. Scrubbing Media Reuse in plant Premises and Sell to end user. Domestic waste water will be disposed of through septic tank & soak pit.

(v) In case, domestic waste water generation is more than 10 KLD, the industry may install STP.

Domestic wastewater (4.0 KL/Day) shall be disposed in septic tank & soak pit.

3. Land (i) Increase of green belt cover by 40% of the total land area beyond the permissible requirement of

Unit has already provided 2631.0 sq. m. i.e. 40.0% of Green belt area within premises.

33%, wherever feasible.

(ii) Stipulation of green belt outside the project premises such as avenue plantation, plantation in vacant areas, social forestry, etc.

We have planted green belt outside the premises within the periphery of the project site.

(iii) Dumping of waste (fly ash, slag, red mud, etc.) may be permitted only at designated locations approved by SPCBs/ PCCs.

We will send the generated hazardous waste to GPCB approved TSDF/ CHWIF site of M/s. BEIL, Ankleshwar.

(iv) More stringent norms for management of hazardous waste. The waste generated should be preferably utilized in co-processing.

We will explore the possibility for disposal of waste generated to be preferably utilized in co-processing.

4. Other Conditions (Additional)

(i) Monitoring of compliance of EC conditions may be submitted with third party audit every year.

Monitoring of compliance of EC conditions will be submitted with third party audit every year.

(ii) The % of CER may be at least 1.5 times the slabs given in the OM dated 01.05.2018 for SPA and 2 times for CPA in case of Environment Clearance

We will contribute 2 % of the proposed project cost (2 times % of CER as per OM dated 01.05.2018) for socio economic development activities for 2 year.

(v) Effluent treatment mechanism with plan for Zero Liquid Discharge needs to be

submitted. Now, We Proposed In House MEE plant Followed by Solvent Stripper, ATFD. Total raw water requirement will be 51.58 KL/day (Fresh: 26.58 KLD + Reuse: 25.0 KLD) (Industrial: 41.58 KL/day + Domestic: 5.0 KL/day + Gardening: 5.0 KL/day) which will be met through GIDC water supply. Total waste water generation will be 38.85 KL/day (Industrial: 34.85 KL/day + Domestic: 4.0 KL/day). Waste Stream (Process, Boiler, Cooling, Washing) 29.85 KLD ETP with primary treatment, and send In-House MEE Plant followed by Solvent Stripper. 25 KLD MEE Condensate will be reuse in plant premises. Scrubbing Media Reuse in plant Premises and Sell to end user. Domestic waste water will be disposed of through septic tank & soak pit. (vi) Details of Raw material linkage (S. no. 13.1 of form 2) and its mitigation measure during

transportation needs to be submitted. RAW MATERIAL STORAGE AND HANDLING The raw materials shall be received in MS/SS tank, HDPE/fibre drums and bags as well as through tankers. All the storage tanks of hazardous flammable substances shall be located within premises in separate storage area i.e. Tank farm area shall be stored in MS/SS tank with all precautionary process instrumentation and safety appliances. Large area is covered by well-designed warehouse, which shall be containing store office, raw material store, finished product

store, etc. The personnel protective equipments like hand gloves, safety shoes, goggles, helmet, clothing, etc. will be provided to those handling hazardous chemicals as per requirement. All the motors and electrical connections will be flame proof. List of raw materials are given in Table. STORAGE AND HANDLING DETAILS OF HAZARDOUS CHEMICALS

Sr. No.

Name Of The Hazardous Substance

Maximum Storage

Required Mt/Month

Mode Of Storage

Actual Storage

State & Operating Pressure & Temperature

Possible Type Of Hazards

1 Methanol 5 MT 1125 Drum 200 Liter x 25

NTP Flammable/ Toxic

2 Toluene 4 MT 480 Drum 200 Liter x 20

NTP Flammable/ Toxic

3 Acetone 3 MT 1072 Drum 200 Liter x 15

NTP Flammable/ Toxic

4 Hydrochloric Acid

5 MT 395 Drum 250 Liter x 25

NTP Corrosive

5 IPA (Isopropyl Alcohol)

5 MT 970 Drum 250 Liter x 25

NTP Flammable

6 Acetic Acid 5 MT 37 Drum 250 Liter x 25

NTP Toxic

7 Sulphuric Acid

5 MT 440 Drum 250 Liter x 4

NTP Corrosive

8 Sodium Hydroxide

2 MT 48 Bags 50 kg x 40 NTP Toxic

9 Potassium Carbonate

2 MT 70 Bags 50 kg x 40 NTP Toxic

10 Methylene dichloride

2 MT 405 Bags 50 kg x 40 NTP Toxic

11 Ethylene dichloride

3MT 300 Drum 200 Liter x 20

NTP Flammable

12 Aluminum tri chloride

2MT 44 Bags 50 kg x 40 NTP Corrosive

13 Ethyl acetate 2MT 590 Drum 200 Liter x 20

NTP Flammable/ Toxic

14 Nitric Acid 2MT 66 Drum 250 Liter x 25

NTP Corrosive

SAFETY PRECAUTIONS Control measures provided for Solvent storage Area:

1. Construction & Installation of solvent storage facility is provided as per explosive act, (License & local rules / regulation followed).

2. Flame proof electrical fitting & intrinsically safe instruments are installed. 3. Flame arrestor installed on vent pipe with breather valve & emergency vent valve

provided. 4. Earth fault relay trip installed for solvent tanker unloading system (Solvent pump having

interlock with grounding of the tanker to make 100% grounding.).

5. Grounding (double earthing) & Jumper for flange joint provided for all installation & it is monitored periodically.

6. Road Tanker grounded before unloading. 7. Check list is followed for loading & unloading. 8. Leakage collection bund with foam system is provided. 9. Combustible Gas Detection system, Fire (Foam / Powder) extinguisher, Foam monitors

is provided. 10. F-30 coating provided for solvent storage tanks. 11. Nitrogen blanketing system is provided. 12. Closed handling system is provided. 13. Smoke detector system installed at Hydrogen Peroxide storage room. 14. Cooling system provided for Hydrogen Peroxide storage room. 15. In case of High temperature of Hydrogen Peroxide Storage Room, High temp. indication

provided & connected centralized DCS system. Control measures provided for Warehouse:

1. Fixed electrical fitting is provided. Lighting is installed between racks above the gangways & away from material storage to avoid heating to storage goods.

2. Electrical fitting tested periodically (i.e. electrical load thermo graphic temperature measurement, mechanical integrity of cables, physical condition of cable & other electrical appliances / installation.)

3. BT reach truck battery charging station is provided outside of ware house. 4. Appropriate passage, gangways provided. 5. Fire detection system (Beam Detector) provided. 6. Adequate portable fire extinguishers installed at noticeable position & kept easily

accessible. 7. Fire hydrant system provided. 8. Auto sprinkler system provided on individual racks compartments at Ware House: this

system is independent system having Separate Pumps with separate piping from Pump House to Ware House, it consists of automatic operated sprinkler on 59°C.

9. Fire Alarm System: Automatic fire detection & alarm system consists of Fire Detectors, Addressable Manual Call Points (MCP) & Hooters Beam Detectors (Ware House) are placed at strategic locations and connected by cable to central control panel at ECC with repeater panel at DCS Control Room.

10. Emergency exit provided. 11. A warehouse is used exclusively for storage activities. Loose chemical handling not

allowed. 12. Chemical segregation is done based on reactivity. 13. In case of maintenance work, Ignition sources controlled by hot work permit system. 14. Natural & Eco ventilator is provided. 15. Proper drainage system is provided for used fire water.

PRECAUTIONS DURING STORAGE AND TRANSPORTATION OF HAZARDOUS CHEMICALS LIQUIDS

• Vendor will be asked to provide MSDS to Driver.

• Truck will have clearly marked identification of material being contained with mentioning Safety Card.

• Driver to have concerned Safety Officer’s contact details to contact him in case of emergency.

• Provide muffler on exhaust while entering tanker within premises.

• Ensure Earthing Boss connection before starting any transferring.

• SOP to cover routine checking of Solvent storage area to be carried out for checking any spillage / leakage.

• Readings of Temperature & Pressure will be noted, recorded & reported immediately for abnormality.

• Safety instruments like rupture disc, safety valves will be checked at defined duration for intake.

• Barrels to be checked for proper fixing of bungs before sending it outside the premises.

• Barrels to be monitored physically daily for developing any pressure or vacuum within it on long storage.

• Concerned persons will be trained properly to use spill kit in case of observing any spillage inside warehouse.

SOLIDS

• Vendor will be asked to provide MSDS to Truck Driver.

• Driver to have concerned Safety Officer’s contact details to contact him in case of emergency.

• Provide muffler on exhaust while entering truck within premises.

• SOP to cover routine checking of Bags & Containers for checking any damage.

• Containers to be tested for safe racking & transportation.

• Proper PPE to be used while handling the material & concerned persons to be trained for usage of the same.

• Concerned persons will be trained properly to use spill kit in case of observing any spillage inside warehouse.

Hazard Identification In the storage of chemical & manufacturing operation various flammable / toxic / corrosive material, compressed gases are utilized &also the stock of the combustible material is maintained. These items have potential to lead to an accident (explosion / fires etc). The major industrial hazards can be divided into following different categories.

1. FIRE HAZARD. 2. EXPLOSION HAZARD. 3. TOXIC HAZARD. 4. Electrical Hazard 5. Mechanical Hazard

Above hazard should be taken into consideration because some of the chemical used, stored are having inflammable / flammable, toxic, corrosive and explosion properties. FIRE HAZARD

The fire may take place because of any one or more of the following reasons, � Naked Flame � Hot Surface � Electric Spark � Static Electricity � Rise in Temperature & Pressure beyond permissible limits.

To prevent the fire hazards, following actions have been taken. � Naked flame, hot surface and other ignition sources are eliminated from the

areas where flammable substances are stored and handled. � Storage and process area are posted with "No Smoking" sign. � An earthing terminal for use during transfer operation. � Flame proof electrical wiring wherever needed is installed at plant and stores

building.

� Pump body, drive motor and associated electrical switchgear are earthed properly.

To control the fire hazards, following provisions made available. � FIRE DETECTION SYSTEM: - The fire alarm gets activated by automatic detection devices, like Smoke, Heat and Optical detectors installed at various potential fire prone places at site. At certain place (MCP) Manual call points are also provided. This system can be activated on that particular point in case, fire is observed. The copy of the drawing is attached in part 2ND.

PORTABLE FIRE EXTINGUISHERS & SAND BUCKETS: - There are many fire extinguishers and sand buckets installed in various buildings in the premises. No. of extinguishers installed in the plant area based on the location of hazardous chemical and process carried out. All the fire extinguishers have name of the manufacture and ISI mark on it. Storage near extinguisher is avoided for easy approach and the service contract is provided for servicing the fire extinguishers on monthly basis.

Table-FFA (Proposed) Type of Fire Extinguishers

Number of Fire extinguishers

Fire Water Reservoir Capacity

Fire Pump Capacity

Hydrant Pressure

Tanks covered by Sprinklers

Details deluge valve arrangements

Fire tenders available

Foam Type and quantity

Other relevant details

Foam 4 9 ltr -- 15BAR -- -- -- -- -- CO2 Powder

2 100 KL 56MTR 5.0 Kg/cm2

NA NA -- -- --

Dry Chemical Powder

4 6 kg -- 15 bar -- -- -- -- --

ABC 1 LIST OF PERSONEL PROTECTIVE EQUIPMENT

1) Safety Helmet: - Individual 2) Safety Shoes: - Individual 3) Hand Gloves: - Individual 4) Nose Mask: - Individual 5) Safety Goggles: - Individual

DETAILS OF FIRE FIGHTING ARRANGEMENTS Sr No

AREA OF INSTALLATION

NO. OF CO2 Fire Extinguisher Installed

NO.OF DCP Fire Extinguisher Installed

Sand Bucket Installed

1 Process Plant Area 8 NOS 2 Electric Panel Room 2 NOS 3 Ware House 4 Tank Farm MOBILE FOAM UNIT

150LTR 1 SET (4

BUCKET 1 STAND)

5 Office 1 NOS 6 Utility 7 Process Area FIRE HYDRANT SYSTEM: Fire hydrant system is provided to protect entire plant and non-plant area. It consists of external (Yard) Hydrants, internal hydrants, fire escape hydrants and water / foam monitors. And sufficient amount of water in underground tanks are available. In the pump house six pumps are installed. (One diesel driven pump, two electrical operated pumps & three jockey pump.) The jockey pump is always in auto system to maintain the pressure in the hydrant system. FIXED FOAM SYSTEM: The fixed foam system is provided for solvent tank farm area & foam system for protection of bund area of solvent tank farm is provided. Floor wise auto operated spot foam protection system is provided for selected reactors / vessels in production building. SPRINKLER SYSTEM: Auto operated sprinkler system is provided for raw material & finish goods warehouse. The sprinkler system is independent system having separate pumps with separate piping from pump house to warehouse. FIRE WATER STORAGE: Separate concrete fire water storage tank is provided. The tank is constructed in two compartments with baffle wall in between not going right down to the base of the tank. This arrangement ensures proper circulation of the fire water and prevents stagnation. Fire Water retention: Separate concrete fire water retention tank is provided. The tank capacity is 1000 M3 & working capacity is 750 M3 (It is equivalent to fire water storage tank) Explosion hazard

The second major hazards after fire in industry are explosion. Explosion hazard is normally more dangerous than the fire hazard as it causes greater damage and loss to property. The explosion may take place because of any one or more of the following reasons,

� With exposure to spark / flame. � Explosion due to vapor in flammable concentration. � Due to inherent oxygen. � Static electricity or open flame.

To prevent the explosion hazards, following actions have been taken. � Temperature indicator, Alarm system & interlocking system are provided on the

basis of risk analysis on necessary equipment. To control the explosion hazards, following actions have been taken.

� Rupture Disc & Safety Valve provided as per necessity on equipment. TOXIC HAZARD: -

A chemical can find entry into human body through various routes such as injection, inhalation or skin contact.

To prevent the toxic hazards, following actions have been taken. Exposure Control Arrangement: All bulk critical materials are handled in closed system. Solid handling is done through charging hopper having dust extraction hood. Vents are connected to the scrubber system to prevent human exposure.

� Efficient exhaust system is provided wherever necessary in the plant. � Scrubber system is also provided to the reactors in the plant to scrub the vapors

of the chemical. To control the toxic hazards, following provisions made available.

� To avoid chemicals, contact with body, suitable respiratory / non respiratory personal protective equipment’s are provided.

� Spillage of any chemical will be avoided to the maximum extent by closed circuit system i.e. day tanks are provided with an overflow line having bigger diameter than that of inlet of the pipe diameter. Standard operating procedures are available to handle spillage and leakage.

� Suitable posters & short work procedure showing dangerous properties of the chemical are also displayed in the working area.

� Arrangement for combating spills of these chemicals such as wash water / sand / neutralizing agents / absorbents for covering up made available nearby.

� The Personnel are also suitably trained in the use of the chemicals before giving responsibility.

� Periodic medical check-up of employees & contract Personnel is being carried out. If any worker shows any indication of exposure due to chemical, suitable preventive measures are being takes place.

� In case of major toxic release all employee will be assembled at admin building and then transfer to safer shelter (Company Guest House) by transport.

Company will make agreement with supplier of raw material after getting EC & CTE. Some raw material will be imported and some will be local.

Sr. No.

Product Name Cas No. Mt/Annum Source Mode Of Transport

Distance Of Source From Project Site In Kilometers

Linkage

GROUP-1

1 Canaglifozin 842133-18-0

2-(5- bromo-2-methylbenzyl)-5-(-4-fluorophenyl)thiophene

1030825-20-7

765.0 Domestic By Road 500 Open Market

2,3,4,6-tetra-O-trimethylsilyl-β-D-gluconolactone

32384-65-9

561.0 Imported/Domestic By Air/Sea/Road

500 Open Market

n-butyl lithium 109-72-8 112.2 Domestic By Road 500 Open Market

THF 109-99-9 2040 Domestic By Road 500 Open Market

Methanol 67-56-1 2550 Domestic By Road 400 Open Market

Methylene dichloride 75-09-2 3060 Domestic By Road 500 Open Market

Triethylsilane 617-86-7 275.4 Domestic By Road 900 Open Market

Boron trifluoride etherate

109-63-7 346.8 Domestic By Road 50 Open Market

Sodium carbonate 497-19-8 300.9 Domestic By Road 50 Open Market

2 Dapaglifozin 461432- Open

26-8 Market

5-bromo-2-chloro-4 -ethoxy diphenylmethane

86845-35-4

695.4 Domestic By Road 50 Open Market

2,3,4,6-tetra-O-trimethylsilyl-β-D-gluconolactone

32384-65-9

417.24 Imported/Domestic By Air/Sea/Road

500 Open Market

n-butyl lithium 109-72-8 102 Domestic By Road 50 Open Market

Toluene 108-88-3 1854.6 Domestic By Road 50 Open Market

Methanol 67-56-1 2318.16 Domestic By Road 50 Open Market

Methylene dichloride 75-09-2 2781.84 Domestic By Road 50 Open Market

Triethylsilane 617-86-7 222.6 Domestic By Road 50 Open Market

Boron trifluoride etherate

109-63-7 324.6 Domestic By Road 50 Open Market

3 Empagliflozin 864070-44-0

Open Market

(3S)-3-[4-[(5-bromo-2-chlorophenyl) methyl] phenoxy] tetrahydrofuran

915095-89-5

709.56 Domestic By Road 50 Open Market

2,3,4,6-tetra-O-trimethylsilyl-β-D-gluconolactone

32384-65-9

416.88 Imported/Domestic By Air/Sea/Road

500 Open Market

n-butyl lithium 109-72-8 97.56 Domestic By Road 50 Open Market

THF 109-99-9.

2217.36 Domestic By Road 50 Open Market

Methanol 67-56-1 2660.88 Domestic By Road 50 Open Market

Methylene dichloride 75-09-2 2660.88 Domestic By Road 50 Open Market

Triethylsilane 617-86-7 230.64 Domestic By Road 50 Open Market

Boron trifluoride etherate

109-63-7 310.44 Domestic By Road 50 Open Market

Sodium carbonate 497-19-8 270.48 Domestic By Road 50 Open Market

4 Levosulpiride 23672-07-3

50 Open Market

Mono ethylene glycol 107-21-1 1020 Domestic By Road 50 Open Market

2-methoxy-5 sulphomyl methyl benzoate

33045-52-2

765 Domestic By Road 50 Open Market

(S-) 1- ethyl-2- aminomethylpyrolindine

22795-99-9

397.8 Imported/Domestic By Air/Sea/Road

500 Open Market

5 Ambroxol Hydrochloride

23828-92-4

50 Open Market

Ambroxol base 23828-92-4

816 Domestic By Road 50 Open Market

IPA 67-63-0 8160 Domestic By Road 50 Open Market

Hydrochloric acid 7647-01-0

207.06 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

15.3 Domestic By Road 50 Open Market

6 2,4-Difluoro Aniline 367-25-9 Open Market

2,4 Difluoronitrobenzene

446-35-5 1295.4 Imported/Domestic By Air/Sea/Road

500 Open Market

Catalyst - Raney Nickle /(pd/c)

7440-05-3

7.14 Domestic By Road 50 Open Market

Hydrogen Gas 1333-74-0

51 Domestic By Road 50 Open Market

Liq NH3 (25%) 1336-21-6

4.08 Domestic By Road 50 Open Market

7 2,4-Difluoro Nitro Benzene

446-35-5 Open Market

2,4 Dichloronitrobenzene

611-06-3 1326 Imported/Domestic By Air/Sea/Road

500 Open Market

Potassium Fluoride 7789-23-3

856.8 Domestic By Road 50 Open Market

8 Calcium Chloride 10043-52-4

Open Market

Lime stone/CaCo3 471-34-1 918 Domestic By Road 25 Open Market

HCL(30%) 7647-01-0

2244 Domestic By Road 25 Open Market

9 3-Amino Benzotrifluoride

98-16-8 Open Market

Benzotrifluoride 98-08-8 907.8 Imported/Domestic By Air/Sea/Road

500 Open Market

98% Nitric Acid 7697-37-2

399.84 Domestic By Road 30 Open Market

98% Sulphuric Acid 7664-93-9.

627.3 Domestic By Road 30 Open Market

Solvent-Ethylene Dichloride

107-06-2 2040 Domestic By Road 30 Open Market

Iron (Fe) 7439-89-6

887.4 Domestic By Road 50 Open Market

Acetic Acid 64-19-7 18.36 Domestic By Road 30 Open Market

Soda Ash 497-19-8 673.2 Domestic By Road 50 Open Market

10 2,3,4-Tri Chloro Nitro Benzene

17700-09-03

Open Market

1,2,3-TCB 87-61-6 795.6 Imported/Domestic By Air/Sea/Road

300 Open Market

H2SO4(98%) 7664-93-9

493.68 Domestic By Road 30 Open Market

HNO3(98%) 7697-37-2

280.5 Domestic By Road 30 Open Market

NaHCO3 144-55-8 25.5 Domestic By Road 50 Open Market

11 5-Amino-2- Methyl Benzene Sulphonic Acid Phenyl Ester

118-88-7 Open Market

2-Methyl -5 -Nitro Benzene Sulphonyl Chloride

465514-07-2

999.6 Domestic By Road 50 Open Market

Phenol 108-95-2 399.84 Domestic By Road 30 Open Market

Sodium Hydroxide 1310-73-2

169.32 Domestic By Road 30 Open Market

Iron Powder 7439-89-6

538.56 Domestic By Road 30 Open Market

Acetic Acid 64-19-7 20.4 Domestic By Road 50 Open Market

Sodium Carbonate 497-19-8 15.3 Domestic By Road 30 Open Market

Solvent –ODCB 509-34-2 1530 Domestic By Road 50 Open Market

12 2,3,4,5,6-Penta Chloro Pyridine

2176-62-7

Open Market

Pyridine 110-86-1 346.8 Domestic By Road 30 Open Market

Chlorine Gas 7782-50-5

1708.5 Domestic By Road 30 Open Market

Catalyst -FeCL3 7440-05-3.

25.5 Domestic By Road 30 Open Market

Dilute NaOH solution 1310-73-2

1764.6 Domestic By Road 50 Open Market

13 2,4-Di Chloro Phenol 120-83-2 3 Open Market

Para chloro Phenol 106-48-9 2284.8 Domestic By Road 30 Open Market

Anhydrous Ferric Chloride

10025-77-1

12.24 Domestic By Road 30 Open Market

Chlorine Gas 7782-50-5

446.76 Domestic By Road 30 Open Market

10% Soda Ash Solution 497-19-8 204 Domestic By Road 50 Open Market

14 4-Amino Benzotrifluoride

455-14-1 30 Open Market

4-Chlorobenzotrifluoride

98-56-6 1275 Imported/Domestic By Air/Sea/Road

500 Open Market

Liquid Ammonia(25%) 1336-21-6

1156.68 Domestic By Road 30 Open Market

15 3-Nitro Acetophenone 121-89-1 Open Market

Acetophenone 98-86-2 981.24 Domestic By Road 30 Open Market

98% Sulphuric acid 7664-93-9

2725.44 Domestic By Road 30 Open Market

98% Nitric acid 7697-37-2

516.12 Domestic By Road 30 Open Market

Solvent-Ethylene Dichloride

107-06-2 3060 Domestic By Road 50 Open Market

15% Soda Ash Solution 497-19-8 510 Domestic By Road 30 Open Market

Methanol 67-56-1. 3060 Domestic By Road 50 Open Market

16 3-Amino Acetophenone

99-03-6 Open Market

3-Nitro Acetophenone 121-89-1 1275 Imported/Domestic By Air/Sea/Road

500 Open Market

Solvent- Methanol 67-56-1 3060 Domestic By Road 30 Open Market

Catalyst - Raney Nickle 12635-27-7

25.5 Domestic By Road 50 Open Market

Hydrogen Gas 1333-74-0

19.38 Domestic By Road 50 Open Market

17 3-Hydroxy Acetophenone

121-71-1 Open Market

3-Amino Acetophenone 99-03-6 1275 Imported/Domestic By Air/Sea/Road

500 Open Market

98% Sulphuric acid 7664-93-9.

1275 Domestic By Road 25 Open Market

Sodium Nitrite 7632-00-0

693.6 Domestic By Road 25 Open Market

15% Soda Ash Solution 497-19-8 510 Domestic By Road 30 Open Market

18 3-Acetoxy Acetophenone

2454-35-5

Open Market

3- Hydroxy Acetophenone

121-71-1 816 Imported/Domestic By Air/Sea/Road

500 Open Market

Caustic Lye(50%) 1310-73-2

530.4 Domestic By Road 50 Open Market

Acetic Anhydride 108-24-7 673.2 Domestic By Road 50 Open Market

19 Lurasidone Hydrochloride

367514-88-3

Open Market

(1R,2S,3R,4S)-N-[ (1R,2R)-2-[4-(1,2-Benzisothiazole-3yl)-1-piperizinylmethyl]-1-

367514-88-3

1275 Imported/Domestic By Air/Sea/Road

500 Open Market

cyclohexylmethyl]-2,3-bicyclo[2,2,1] heptanedicarboxyimide (Lurasidone free base)

Conc. hydrochloric acid 7647-01-0

261.12 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

132.6 Domestic By Road 25 Open Market

Celite 68855-54-9

510 Domestic By Road 30 Open Market

Acetone 67-64-1 10200 Domestic By Road 50 Open Market

20 2,6 Difluororbenzonitrile

1897-52-5

Open Market

2,6 Dichlororbenzonitrile

1194-65-6

1261.74 Domestic By Road 30 Open Market

Potassium Fluoride 7789-23-3

851.7 Imported/Domestic By Air/Sea/Road

500 Open Market

NMP 872-50-4 3570 Domestic By Road 30 Open Market

21 2,6 Difluorobenzamide

18063-03-1

Open Market

2,6 Difluorobenzonitrile 1897-52-5

902.7 Domestic By Road 50 Open Market

HCL (30%) 7647-01-0

394.74 Domestic By Road 50 Open Market

Methanol 67-56-1 3060 Domestic By Road 20 Open Market

GROUP-2 Open Market

22 3,4,5-Trimethoxy Benzoic Acid

18-41-2 511.2 Open Market

Para Cresol 106-44-5 1080 Domestic By Road 25 Open Market

Solvent-EDC 107-06-2 1515.6 Domestic By Road 20 Open Market

Bromine (Liquid) 7726-95-6

500.4 Domestic By Road 20 Open Market

Sodium methoxide(CH30Na)

124-41-4 864 Domestic By Road 50 Open Market

Solvent-Methanol 67-56-1 1158.48 Domestic By Road 50 Open Market

Di Methyl Sulphate 77-78-1 788.4 Domestic By Road 70 Open Market

Caustic Lye 1310-73-2

33.84 Domestic By Road 50 Open Market

Catalyst 1314-15-4

123.84 Domestic By Road 70 Open Market

DMF 68-12-2 2160 Domestic By Road 75 Open Market

Solvent – Toluene 108-88-3 436.32 Domestic By Road 50 Open Market

MNO2 1313-13-9

579.6 Domestic By Road 50 Open Market

H2SO4 (98%) 7664-93-9

393.84 Domestic By Road 50 Open Market

Nascent Oxygen 7782-44-7

511.2 Domestic By Road 50 Open Market

23 3,4,5 - Trimethoxy Benzaldehyde

86-81-7 Open Market

Para Cresol 106-44-5 500.4 Domestic By Road 25 Open Market

Solvent-EDC 107-06-2 864 Domestic By Road 50 Open Market

Bromine (Liquid) 7726-95-6

1487.52 Domestic By Road 50 Open Market

Sodium methoxide(CH30Na)

124-41-4 491.04 Domestic By Road 15 Open Market

Solvent-Methanol 67-56-1 864 Domestic By Road 50 Open Market

Di Methyl Sulphate 77-78-1 1135.44 Domestic By Road 50 Open Market

Caustic Lye (50%) 1310-73-2

773.28 Domestic By Road 50 Open Market

Catalyst 1314-15-4

34.56 Domestic By Road 50 Open Market

DMF 68-12-2 125.28 Domestic By Road 50 Open Market

Solvent – Toluene 108-88-3 2160 Domestic By Road 50 Open Market

MNO2 1313-13-9

433.44 Domestic By Road 50 Open Market

H2SO4 (98%) 7664-93-9.

578.16 Domestic By Road 50 Open Market

24 3,4-Difluoro Benzonitrile

369-34-6 Open Market

3,4-Dichloro Aniline 95-76-1 741.8182 Imported/Domestic By Air/Sea/Road

500 Open Market

98% Sulphuric acid 7664-93-9.

1372.909 Domestic By Road 50 Open Market

Nitrosyl Sulphuric Acid-40%

1454.728 Imported/Domestic By Air/Sea/Road

500 Open Market

Copper Cyanide 544-92-3 409.6363 Domestic By Road 50 Open Market

stage-2 0 Open Market

3,4-Dichloro Benzonitrile

17626-40-3

950.4 Imported/Domestic By Air/Sea/Road

500 Open Market

Potassium Fluoride 7789-23-3

798.48 Domestic By Road 50 Open Market

Catalyst 1314-15-4

7.2 Domestic By Road 50 Open Market

Sulpholane 126-33-0 1080 Domestic By Road 50 Open Market

25 S-(+)-2-Aminobutyramide Hydrochloride

7682-20-4

Open Market

Methyl 2-bromo butyrate

3196-15-4

2196 Imported/Domestic By Air/Sea/Road

300 Open Market

Ammonia 7664-41-7

2736 Domestic By Road 50 Open Market

Potassium Carbonate 584-08-7 835.2 Domestic By Road 50 Open Market

L(+) TARTRIC ACID 87-69-4 846 Domestic By Road 50 Open Market

Acetic acid 64-19-7 285.12 Domestic By Road 50 Open Market

Sulphuric acid 7664-93-9

1224 Domestic By Road 50 Open Market

Methanol 67-56-1 7200 Domestic By Road 50 Open Market

Conc. hydrochloric acid 7647-01-0

658.8 Domestic By Road 40 Open Market

Isopropyl alcohol 67-63-0 2520 Domestic By Road 50 Open Market

26 Levetiracetam 102767-28-2

Open Market

S-(+)-2-AMINOBUTYRAMIDE HYDROCHLORIDE

7682-20-4

705.6 Imported/Domestic By Air/Sea/Road

500 Open Market

4-Chlorobutanoyl chloride

4635-59-0

789.84 Domestic By Road 50 Open Market

Anhydrous sodium sulphate

7757-82-6

1058.4 Domestic By Road 30 Open Market

Potassium hydroxide 1310-58-3

1375.2 Domestic By Road 30 Open Market

Tetra butyl ammonium bromide

1643-19-2

82.08 Domestic By Road 30 Open Market

Celite 68855-54-9

398.88 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

100.8 Domestic By Road 50 Open Market

Dichloromethane 75-09-2 7200 Domestic By Road 50 Open Market

Ethyl acetate 141-78-6 6480 Domestic By Road 50 Open Market

27 Etiracetam 102767-28-2

Open Market

Metyhl 2-bromobutanoate

3196-15-4

1350 Imported/Domestic By Air/Sea/Road

600 Open Market

4- Chlorobutanoyl chloride

4635-59-0

1051.2 Domestic By Road 50 Open Market

Ammonia 7664-41-7

1795.68 Domestic By Road 30 Open Market

Sodium sulphate 7757-82-6

958.32 Domestic By Road 30 Open Market

Potassium hydroxide 1310-58-3

1740.96 Domestic By Road 50 Open Market

Methanol 67-56-1 5760 Domestic By Road 50 Open Market

Ethyl acetate 141-78-6 2160 Domestic By Road 50 Open Market

Dichloromethane 75-09-2 5760 Domestic By Road 20 Open Market

GROUP-3 Open Market

28 Acetophenone 98-86-2 Open Market

Benzene 71-43-2 225 Domestic By Road 20 Open Market

Aluminium tri chloride 7446-70-0

298.8 Domestic By Road 25 Open Market

Acetyl chloride 75-36-5 208.8 Domestic By Road 50 Open Market

Ethylene dichloride 107-06-2 540 Domestic By Road 50 Open Market

sodium carbonate 497-19-8 72 Domestic By Road 50 Open Market

29 2-(5- Bromo-2-Methylbenzyl)-5-(-4-Fluorophenyl) Thiophene

1030825-20-7

Open Market

5-bromo-2-methyl benzoic acid

79669-49-1

216 Imported/Domestic By Air/Sea/Road

50 Open Market

Toluene 108-88-3 1080 Domestic By Road 50 Open Market

Thionyl chloride 7719-09-7

108 Domestic By Road 50 Open Market

Aluminium tri chloride 7446-70-0

295.2 Domestic By Road 500 Open Market

2-(4-fluorophenyl) thiophene

58861-48-6

180 Imported/Domestic By Air/Sea/Road

50 Open Market

Water for HCL 7732-18-5

144 Domestic By Road 50 Open Market

Sodium hydroxide 1310-73-2

39.6 Domestic By Road 30 Open Market

sodium carbonate 497-19-8 72 Domestic By Road 35 Open Market

Ethyl acetate 141-78-6 540 Domestic By Road 30 Open Market

Triethyl silane 617-86-7 108 Domestic By Road 35 Open Market

Boron trifluoride etherate

109-63-7 180 Domestic By Road 30 Open Market

30 5-Bromo-2-Chloro-4-Ethoxy Diphenyl Methane

461432-23-5

Open Market

5-bromo-2-chlorobenzoic acid

21739-92-4

390.6 Imported/Domestic By Air/Sea/Road

500 Open Market

Toluene 108-88-3 1080 Domestic By Road 30 Open Market

Oxalyl chloride 79-37-8 187.2 Domestic By Road 30 Open Market

Aluminium tri chloride 7446-70-0

212.4 Domestic By Road 30 Open Market

Phenetole 103-73-1 180 Domestic By Road 25 Open Market

Water for HCL 7732-18-5

144 Domestic By Road 25 Open Market

KOH 1310-58-3

36 Domestic By Road 50 Open Market

sodium carbonate 497-19-8 72 Domestic By Road 60 Open Market

Ethyl acetate 141-78-6 540 Domestic By Road 30 Open Market

Triethyl silane 617-86-7 144 Domestic By Road 30 Open Market

Boron trifluoride etherate

109-63-7 180 Imported/Domestic By Air/Sea/Road

300 Open Market

31 (3s)-3-[4-[(5-Bromo-2-Chlorophenyl) Methyl] Phenoxy] Tetrahydrofuran

915095-89-5

Open Market

5-bromo-2-chlorobenzoic acid

108-88-3 338.4 Imported/Domestic By Air/Sea/Road

500 Open Market

Toluene 108-88-3 1080 Domestic By Road 30 Open Market

Oxalyl chloride 79-37-8 270.72 Domestic By Road 30 Open Market

Aluminium tri chloride 7446-70-0

230.4 Domestic By Road 30 Open Market

Fluorobenzene 462-06-6 367.2 Imported/Domestic By Air/Sea/Road

500 Open Market

Water for HCL 7732-18-5

144 Domestic By Road 30 Open Market

KOH 1310-58-3

36 Domestic By Road 50 Open Market

sodium carbonate 497-19-8 72 Domestic By Road 50 Open Market

Ethyl acetate 141-78-6 540 Domestic By Road 60 Open

Market

Sodium borohydride 16940-66-2

50.4 Domestic By Road 50 Open Market

Sodium chloride 7440-23-5

36 Domestic By Road 50 Open Market

(S)-Tetra hydrofuran-3-ol

86087-23-2

82.8 Imported/Domestic By Air/Sea/Road

500 Open Market

30% HCL 7647-01-0

72 Domestic By Road 50 Open Market

32 Rivastigmine Tartrate 129101-54-8

Open Market

(s)-3-(1-dimethyl amino ethyl) phenol

139306-10-8

180 Imported/Domestic By Air/Sea/Road

500 Open Market

Triethylamine 121-44-8 219.6 Domestic By Road 50 Open Market

N-ethyl-N-methyl carbamoyl chloride

42252-34-6

158.4 Domestic By Road 50 Open Market

Toluene 108-88-3 1440 Domestic By Road 40 Open Market

Sodium bicarbonate 144-55-8 90 Domestic By Road 50 Open Market

30% HCL 7647-01-0

900 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

9 Domestic By Road 60 Open Market

Ethyl acetate 141-78-6 1620 Domestic By Road 60 Open Market

Methanol 67-56-1 1440 Domestic By Road 50 Open Market

L(+)Tartaic acid 87-69-4 163.8 Domestic By Road 50 Open Market

33 3,4,5-Trimethoxy Toluene

6443-69-2

Open Market

Para Cresol 106-44-5 234 Domestic By Road 50 Open Market

Solvent-EDC 107-06-2 540 Domestic By Road 40 Open Market

Bromine (Br2) 7726-95-6

694.44 Domestic By Road 50 Open Market

Sodium methoxide(CH30Na)

124-41-4 232.2 Domestic By Road 40 Open Market

Solvent-Methanol 67-56-1 432 Domestic By Road 50 Open Market

Di Methyl Sulphate 77-78-1 531 Domestic By Road 50 Open Market

Caustic Lye(50%) 1310-73-2

172.8 Domestic By Road 40 Open Market

34 Sildenafil Citrate 171599-83-0

Open Market

5-(2-Ethoxyphenyl)-1- 139756- 180 Imported/Domestic By 500 Open

methyl-3-propyl-1H-pyrazol[4,3-d]pyrimidin-7-one

22-2 Air/Sea/Road Market

Chlorosulfonic acid 7790-94-5

64.8 Domestic By Road 40 Open Market

Citric acid 77-92-9 108 Domestic By Road 30 Open Market

N-methyl piperazine 109-01-3 61.2 Domestic By Road 50 Open Market

Methanol 67-56-1 2880 Domestic By Road 50 Open Market

Acetone 67-64-1 2520 Domestic By Road 40 Open Market

Methylene chloride 75-09-2 1800 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

18 Domestic By Road 50 Open Market

Sodium hydroxide 1310-73-2

18 Domestic By Road 50 Open Market

35 Phenylphrine Hydrochloride

61-76-7 Open Market

m-hydroxy acetophenone

121-71-1 419.4 Imported/Domestic By Air/Sea/Road

500 Open Market

Ethyl acetate 141-78-6 900 Domestic By Road 40 Open Market

Aluminium chloride 7446-70-0

20.16 Domestic By Road 50 Open Market

Liq. Bromine 7726-95-6

244.8 Domestic By Road 50 Open Market

Toluene 108-88-3 900 Domestic By Road 35 Open Market

n-methyl benzyl amine 103-67-3 308.88 Domestic By Road 40 Open Market

Isopropyl alchohol HCL 67-63-0 331.2 Domestic By Road 50 Open Market

Methanol 67-56-1 1440 Domestic By Road 50 Open Market

Catalyst pd/c 7440-05-3

29.88 Domestic By Road 50 Open Market

Hydrogen gas : 1333-74-0

2.34 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

14.4 Domestic By Road 50 Open Market

HCL 7647-01-0

105.12 Domestic By Road 50 50Open Market

Isopropyl alchohol 67-63-0 1440 Domestic By Road 50 Open Market

36 2-Amino 3 - Chloro Benzoic Acid Methyl Ester

6388-47-2

Open Market

2,3 - Di Chloro Benzoic Acid

50-45-3 439.2 Imported/Domestic By Air/Sea/Road

500 Open Market

Liq. NH3(25%) 1336-21-6

1397.16 Domestic By Road 50 Open Market

Catalyst 1318-93-0

11.88 Domestic By Road 50 Open Market

HCL(30%) 7647-01-0

277.2 Domestic By Road 40 Open Market

Water for NH3(S) Scrubbing

7732-18-5

815.04 Domestic By Road 50 Open Market

stage-2 0 By Road 40 Open Market

2-Amino 3-Chloro Benzoic Acid

6388-47-2

352.8 Domestic By Road 50 Open Market

Caustc (NaOH) 1310-73-2

85.68 Domestic By Road 40 Open Market

Dimethyl Sulphate 77-78-1 260.28 Domestic By Road 50 Open Market

37 Nepafenac 78281-72-8

Open Market

2-Amino benzophenone

2835-77-0

399.96 Imported/Domestic By Air/Sea/Road

500 Open Market

Methyl thioacetamide 2949-92-0

320.04 Imported/Domestic By Air/Sea/Road

500 Open Market

t-Butylhypo chloride 507-40-4 242.4 Imported/Domestic By Air/Sea/Road

500 Open Market

Trimethylamine 121-44-8 312 Domestic By Road 50 Open Market

MDC 75-09-2 3200.04 Domestic By Road 40 Open Market

Ethylacetate 141-78-6 720 Domestic By Road 50 Open Market

Raney nickel 12635-27-7

80.04 Domestic By Road 40 Open Market

Tetrahydrofuran 109-99-9 1200 Domestic By Road 50 Open Market

IPA 67-63-0 960 Domestic By Road 50 Open Market

38 Fluconazole 86386-73-4

Open Market

2,4-Difluoro-2-(1H-1,2,4-Triazole-1-YL)acetophenone

86404-63-9

189.48 Imported/Domestic By Air/Sea/Road

500 Open Market

1,2,4 Triazol 288-88-0 85.32 Imported/Domestic By Air/Sea/Road

500 Open Market

Tri methyl silyl Iodide 16029-98-4

113.64 Domestic By Road 50 Open Market

MDC 75-09-2 2842.08 Domestic By Road 40 Open Market

Sodium chloride 7647-14- 94.68 Domestic By Road 50 Open

5 Market

Potassium hydroxide 1310-58-3

757.92 Domestic By Road 40 Open Market

Ethyl acetate 141-78-6 132.6 Domestic By Road 40 Open Market

Citric Acid 77-92-9 1.56 Domestic By Road 50 Open Market

39 Rosuvastatin Calcium 147098-20-2

(R)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methylsulfonyl)amino]-5-pyrimidin yl]-5-pyrimidinyl]-3-hydroxy-5-oxo-6-heptenoic acid methyl acid methyl ester

147118-40-9

432 Imported/Domestic By Air/Sea/Road

500 Open Market

Sodium borohydride 16940-66-2

324 Domestic By Road 50 Open Market

Sodium hydroxide 1310-73-2

342 Domestic By Road 40 Open Market

Acetone 67-64-1 1440 Domestic By Road 35 Open Market

Ethyl acetate 141-78-6 1800 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

3.6 Domestic By Road 50 Open Market

Calcium acetate 62-54-4 68.4 Domestic By Road 50 Open Market

Methanol 67-56-1 1440 Domestic By Road 50 Open Market

Hydrochloric acid 7647-01-0

288 Domestic By Road 50 Open Market

GROUP-4 Open Market

40 Dapoxetine Hydrochloride

129938-20-1

Open Market

β-(dimethyl amino) benzene propanol

108-16-7 63.12 Imported/Domestic By Air/Sea/Road

500 Open Market

1-fluoronaphthalene 321-38-0 51.84 Imported/Domestic By Air/Sea/Road

500 Open Market

Sodium hydroxide 1310-73-2

21.48 Domestic By Road 40 Open Market

Hydrochloric acid 7647-01-0

19.56 Domestic By Road 50 Open Market

Dimethyl Sulfoxide 67-68-5 743.4 Domestic By Road 50 Open Market

n-Propanol 71-23-8 594.96 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

15.12 Domestic By Road 50 Open Market

41 Etoricoxib 202409-33-4

Open Market

Ketosulfone 221615-75-4

94.2 Domestic By Road 50 Open Market

Acetic acid 64-19-7 126 Domestic By Road 50 Open Market

Acetone 67-64-1 150 Domestic By Road 50 Open Market

Ammonium solution 1336-21-6

65.22 Domestic By Road 50 Open Market

CPT-phosphate 93882-12-3

133.8 Domestic By Road 50 Open Market

D M water 7732-18-5

270 Domestic By Road 50 Open Market

Hydroxylamine hydrochloride

5470-11-1

6.6 Domestic By Road 50 Open Market

Isopropyl alchohol 67-63-0 480 Domestic By Road 50 Open Market

Methanol 67-56-1 360 Domestic By Road 50 Open Market

Potassium tetrabutoxide

865-47-4 39 Domestic By Road 40 Open Market

Sodium acetate 127-09-3 16.8 Domestic By Road 50 Open Market

Sodium hydroxide 1310-73-2

18.6 Domestic By Road 40 Open Market

Toluene 108-88-3 300 Domestic By Road 50 Open Market

Tri hydrofuron 109-99-9 120 Domestic By Road 40 Open Market

Trifluro acetic acid 76-05-1 25.2 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

1.32 Domestic By Road 40 Open Market

42 R-(-)-3(Carbamoyl Methyl)-5-Methylhexanoic Acid [R-Cmh Pure]

181289-15-6

Open Market

3-(2-Amno-2-oxoethyl)5-methylhexanoic acid

181289-33-8

105 Imported/Domestic By Air/Sea/Road

500 Open Market

Chloroform 67-66-3 57 Domestic By Road 50 Open Market

(R)-(1)-phenylethylamine

3886-69-9

9 Domestic By Road 40 Open Market

Ethyl acetate 141-78-6 9 Domestic By Road 40 Open Market

Ammonium Carbamide 1111-78- 59.4 Domestic By Road 50 Open

0 Market

NaOH Lye(48%) 1310-73-2

123 Domestic By Road 50 Open Market

HCL(30%) 7647-01-0

241.2 Domestic By Road Open Market

Activated carbon 7440-44-0

7.8 Domestic By Road Open Market

43 Pregabalin 148553-50-8

Open Market

R-(-)-3(Carbamoyl methyl)-5-methylhexanoic acid

181289-33-8

296.52 Domestic By Road 50 Open Market

R(+) -1-Methyl benzyl amine

23294-41-9

159 Domestic By Road 50 Open Market

Methanol 67-56-1. 60 Domestic By Road 50 Open Market

Chloroform 67-66-3 360 Domestic By Road 50 Open Market

Sulphuric acid 7664-93-9

120 Domestic By Road 50 Open Market

Water 7732-18-5

600 Domestic By Road 50 Open Market

NaOH 1310-73-2

25.8 Domestic By Road 50 Open Market

Sodium Hypo chloride 7681-52-9

565.8 Domestic By Road 50 Open Market

Activated carbon 7440-44-0

4.92 Domestic By Road 50 Open Market

Celite 68855-54-9

0.84 Domestic By Road 50 Open Market

Isopropyl alchohol 67-63-0 300 Domestic By Road 50 Open Market

HAZARDOUS PROPERTIES OF THE CHEMICALS, COMPATIBILITIES, SPECIAL HAZARD AND ANTIDOTES

Name of Chemical

CAS No Hazard

F.P (0C)

BP (0C) LEL %

UEL %

SP.GR. 20 0C

VD NFPA H F R

TLV/TWA

IDLH LC50 LD50 Antidote

HCl 7647-01-0

T & C NA 108.56

NA

NA 1.1-1.19

1.267

3 0 1 5 ppm

1000

ppm

4701 ppm 0.5

hours [Rat]

NA Milk of magnesia, drink large quantity of

water

Methanol 67-56-1

T & F 12 64.5 6 36.5

0.7915 1.11 1 3 0 250 ppm

6000

ppm

64000 ppm 4 hours [Rat]

5628 mg/kg [Rat]

Ethanol (30%

solution through oral, 5% solution through

injection)

Isopropyl alcohol

67-63-0

T & F 11.667

82.5 2 12.7

0.78505

2.07 1 3 0 400 ppm

2000

ppm

NA Acute: 5045 mg/kg [Rat]

Novasine Eye Drops

Toluene 108-88-3

T & F 4.444 110.6 1.1

7.1 0.8636 3.1 2 3 0 300 ppm

500 ppm

49000 mg/m

4 hours [Rat]

636 mg/kg [Rat]

Oxygen

Acetone 67-64-1

T & F

-20 56.2 2.6

12.8

0.79 2 1 3 0 750 ppm

2500

ppm

50100 mg/m

8 hours [Rat]

5800 mg/kg [Rat]

flush eyes immediately with water

Liquor Ammonia

7664-41-7

T NA 36 NA

NA 0.9 3.38 3 0 0 17 mg/

m3

300 ppm

2000 ppm 4 hours [Rat]

NA Skin: Wash with Lactic Acid, apply soframycin,

Eye: Benxynate

(Novacin 0.4% Conc.)

Throat: Smelling Ethanol,

Ether

Formic Acid

64-18-6

T, C & F

50 101 10 45 1.22 NA 3 2 1 5 ppm

30 ppm

15 g/m3 ( Rat )

15 min

730 mg/kg (

Rat )

NA

Thionyl Chloride

7719-09-7

T NA 76 NA

NA 1.638 4.1 3 0 0 1 4.87 500 ppm 1Hr Rat

NA Sodium Hydro-

Carbonate (4% Conc.), Milk, Lime

Juice, Milk of Magnesia

Benzene 71-43-2

T & F

-11 80.1 1.3

7.1 0.8765 2.8 2 3 0 1 ppm

500 ppm

10000 ppm 7 hours [Rat].

930 mg/kg [Rat]

Diazem – 1 mg/Kg.

(Intravenous), Epenephia,

Efidrine

Sulphuric acid

7664-93-9

T & C

NA 270 NA

NA 1.84 3.4 3 0 2 3 mg/

m3

15 mg/

m3

510 mg/m

2 hours [Rat]

2140 mg/kg [Rat.]

Milk of magnesia

Nitric acid

7697-37-2

T NA 121 NA

NA 1.408 2.5 4 0 0 4 ppm

25 ppm

244 ppm 0.5

hours [Rat]

NA Milk of magnesia

Bromine 7726-95-6

T 58.78 -7.25 NA

NA 3.11 7.1 3 0 0 0.2 3.0 2600 4160 mg/kg

[Rabbit]

ether solution drops and put

it near victim’s nose

for smell. Apply pure

oxygen

Aluminium

Chloride

7446-70-0

C NA NA NA

NA 2.44 NA 3 0 2 2 mg/

m3

NA LC50=27.1 mg/L 97h

LD50 = 3470

mg/kg ( Rat )

Wash with plenty of

water

N Propanol

71-23-8

F & T

15 97.2 2.1

13.5

0.8 2.07 1 3 0 250 ppm

NA 67882.3 ppm

4 hour(s

) [Mous

e]

1870 mg/kg [Rat.].

NA

Butanol 71-36-3

F & T

28.9 117.7 1.4

11.2

0.81 2.55 1 3 0 250 ppm

NA 8000 ppm 4 hour(s

) [Mous

e]

790 mg/kg [Rat.].

NA

(vii) Proposed Green belt development program along-with time line and budgetary allocation needs to be provided(green belt has not mentioned as per OM Dated 31.10.2019-CPA) (viii) Details of Court case if any.

GREEN BELT Tree plantation is known for improving the aesthetic and climatologically environment of an area and properly designed green belt can help in ameliorating air pollution to a very significant degree. It should be borne in mind that the green belt will be most effective as a sink for particulate matter and gaseous emissions from ground level sources, such as, fugitive emissions. Effectiveness of green belt for the elevated sources is rather limited but its action as a green lung greatly helps in improving the air quality of the area. However, considerable scope exists for strengthening the existing green belt and developing the same in future. Break up of different land use of factory Total 6578.40 sq. meter land area is available at site; out of this area about 2631.36 sq. meter (40%) area is covered as greenbelt and other forms of greenery. Good greenery shall be maintained in and around the site by planting various types of tress and maintaining lawns. A green belt shall be developed within the site boundary and across the premises inside roads. Trees like Neem, Gulmohar, Peepal, Palm Trees, Shevga, Jangli badam etc. shall be planted in and around the site.

Year No. of trees Capital cost in Rs.

2020 210 3,15,000 2021 210 3,15,000 2022 210 3,15,000

(viii) Updated status of water approval. Total raw water requirement will be 51.58 KL/day (Fresh: 26.58 KLD + Reuse: 25.0 KLD) which will be met through GIDC water supply. Permission obtained from the concern authority for supply of raw water:

(ix) In view of the above, PP/Consultant are requested to revise the application for grant of EC and accordingly revise the Form 2 along with EIA/EMP Report. The EIA/EMP Report shall match with the information as filled in Form 2. On examination it is observed that the Consultant has not adequately submitted the application as per the provisions of the EIA Notification, 2006. Consultant has to read the documents before uploading the information in Form 2 /EIA/EMP report.

Revised EIA Report uploaded as per new Formats.