Upload
others
View
4
Download
4
Embed Size (px)
Citation preview
© Fraunhofer
MARINE BIOTECHNOLOGY
IN SCHLESWIG-HOLSTEIN
Dr. Marina Gebert
14.03.2017
© Fraunhofer
http://www.vliz.be/wiki/Portal:Marine_Biotechnology
(Aqua-)
Marine Biotechnology Workflow(Source: European Science Foundation)
Marine Biotechnology is part of global biotechnology and its specificity lies in the uniqueness of marine
living resources and their derived products and services through the use of a set of tools ranging from
biodiversity assessment to systems biology, from cultures to engineering.
© Fraunhofer
Target research area Examples
Food:
Development of food products and ingredients
of marine origin (algae, invertebrates, fish) with
optimal nutritional properties for human health
dietary supplements; functional food
selective breeding of aquaculture species
sustainable production of feed
zero-waste recirculation systems
Energy:
Development and demonstration of viable renewable
energy products and processes, notably through the
use of marine algae
microalgae resources for biofuel production
improve the photosynthetic efficiency
enhance lipid productivity
improve harvest, separation, purification
processes
Health:
Development of novel drugs, treatments and health
and personal care products
Finding novel bioactives
improve technical aspects
overcome the supply problem
anti cancer, biofilm inhibitors, antibiotics
Industrial Products and Processes:
Development of marine-derived molecules exploitable
by industry including enzymes, biopolymers and
biomaterials
develop enabling technologies for high
throughput enzyme screening
marine biopolymers as novel competitive
commercial products in food, cosmetics and
health
Environment:
Development of biotechnological approaches,
mechanisms and applications to address key
environmental issues
Develop automated high-resolution
biosensing technologies
Antifouling strategies
restauration of (marine) ecosystems
biosensors for routine analysis
Marine Biotechnology research priorities
Adapted from: European Science Foundation, Position Paper 15,
Marine Biotechnology: A New Vision and Strategy for Europe
© Fraunhofer
Masterplan Marine Biotechnology Schleswig-Holstein
Marine Biotechnology
Marine
bioresources
Technologies/
methods
Raw materials/
intermediate
products
Product areas
(examples)Application areas
uses benefits from produces develops products for is applied in
Macro-organisms:
Plants
Animals
Microorganisms:
bacteria
Genetics /
genomics
Biochemistry /
proteomics
Cell biology
techniques
Metabolomics
Cultivation
methods
Systems biology
Ecological methods
Proteins:
Collagen
Carbohydrates:
Agar
Lipids:
Omega-3
fatty acids
Secondary
metabolites:
Polyketides
Pharmaceuticals
Feed
Dietary
supplements
Antifouling
Cosmetics
Chemicals
Industrial
biotechnology
Biofuels
Health
Aquaculture
Food
Cosmetics
Industry
Energy
Adapted from: Masterplan Marine Biotechnologie Schleswig-Holstein
© Fraunhofer
Marine Biotechnology R&D in Schleswig-Holstein
Source: Masterplan Marine Biotechnologie Schleswig-Holstein
© Fraunhofer
Marine Biotechnology companies in Schleswig-Holstein
Source: Masterplan Marine Biotechnologie Schleswig-Holstein
© Fraunhofer
Examples of policy guidelines and initiatives on national
and international level
European level National level
Policy guidelines
• An Integrated Maritime Policy for the
European Union -The Blue Book
• Blue growth strategy
• High-tech strategy 2020 for Germany
• National research strategy bio economy
2030
• National masterplan of maritime
technologies
Initiatives
Programs • Horizon 2020 • Diverse federal programs, e.g. „KMU-
innovativ“, „Basic technologies for the
next generation of biotechnological
processes“
Projects and initiatives • Micro B3
• SUBMARINER
• Susfood
• ANIHWA
• INTERREG Baltic Blue Growth
• JPI Oceans, Marine KIC, EuroMarine,
Marine Fungi, …
• Food security through aquaculture in
Malawi
• Origin and function of metaorganisms
• Sun protection from macroalgae
• Offshore cultivation of microalgae
Networks, associations • ERA-Net MB
• ERASysBio
• ERA-NanoSci
• ERA-Net Bioenergy
• ETPs (European technology platforms)
• …
• Bundesverband Aquakultur e.V.
• Kieler Algenstammtisch
• Kompetenznetzwerk Aquakultur
• Maritimes Cluster Norddeutschland
• Nordverbund Marine Biotechnologie
Adapted from: Masterplan Marine Biotechnologie Schleswig-Holstein
© Fraunhofer
Companies involved in national or international funding
programs (n=17)
Source: Masterplan Marine Biotechnologie Schleswig-Holstein
No
Yes
Yes, european
Yes, european
and german
© Fraunhofer
Main challenges for MB companies during cooperation
with scientific institutions
Lacking financial means
„Slow“ structures at cooperation
partners
Uncertain legal structures (IPR,
liability)
Missing interest of cooperation
partner
Commercial risk is too high
Spatial distance
Communication during project
Finding cooperation partners and
making contact
Decreasing interest of partner during
cooperation
Want of confidence to cooperation
partner
Adapted from: Masterplan Marine Biotechnologie Schleswig-Holstein
© Fraunhofer
Main challenges for MB R&D Institutes during
cooperation with companies
Economic potential unclear
Communication and making
contacts is too difficult
Differing interests
Difficulties accessing information
Uncertain legal structures (IPR,
liability)
Spatial distance
Lacking financial means
Decreasing interest of partner during
cooperation
Missing interest of cooperation
partner
Competitive situation
Incapable of action
Adapted from: Masterplan Marine Biotechnologie Schleswig-Holstein
© Fraunhofer
The Fraunhofer-Gesellschaft at a Glance
The Fraunhofer-Gesellschaft undertakes applied research of direct utility
to private and public enterprise and of wide benefit to society.
Nearly 24,000
staff
More than 70%
is derived from
contracts with industry
and from publicly
financed research
projects.
Almost 30%
is contributed by the
German federal and
Länder Governments.
66 institutes and research units Fin
an
cin
gvo
lum
e
€2 billion
2014
Co
ntr
ac
tR
es
earc
h
€1.7
billion
Major infrastructure
capital expenditure and
defense research
© Fraunhofer
The Fraunhofer-Gesellschaft
in Germany
München
Holzkirchen
Freiburg
Efringen-
Kirchen
FreisingStuttgart
PfinztalKarlsruheSaarbrücken
St. IngbertKaiserslautern
DarmstadtWürzburg
Erlangen
Nürnberg
Ilmenau
Schkopau
Teltow
Oberhausen
Duisburg
EuskirchenAachenSt. Augustin
Schmallenberg
Dortmund
PotsdamBerlin
Rostock
LübeckItzehoe
Braunschweig
Hannover
Bremen
Bremerhaven
Jena
Leipzig
Chemnitz
Dresden
Cottbus
Magdeburg
Halle
Fürth
Wachtberg
Ettlingen
Kandern
Oldenburg
Freiberg
Paderborn
Kassel
GießenErfurt
Augsburg
Oberpfaffenhofen
Garching
Straubing
Bayreuth
Bronnbach
Prien
Fraunhofer Institution for Marine
Biotechnology and Cell Technology (EMB)
© Fraunhofer
Cell Technologies
Cell culture of aquatic organisms
In-vitro manipulation
Cryopreservation
Cellular test systems
Technical Center for Applied Food Research–
TFAL
Food and feed from aquatic resources
Food-Prototypes
Dietary supplements
Land-based integrated multitrophic
aquaculture
Integrated cultivation of plants/ algae and
animals in marine aquaculture systems
controlled environment
saving water
broader product range
Breeding of novel aquaculture candidates
Implementation of omnivor species
Reduction of fish meal and oil
Working group „Aquatic cell technology and Aquaculture“
© Fraunhofer
Koi-Herpes-Virus-
Diagnostics and containment of CyHV-3 in carp aquaculture
Control, 4 d Control, 6 d Control, 8 d
Virus I, 4 d Virus II, 6 d Virus II, 8 d
Quelle: http://www.laves.niedersachsen.de
Our expertise in fish cell culure development
allows us to develop novel cell lines (from skin,
gill, brain, head kidney,…) that can produce
high amounts of virus particles
Viruses are used as source material for the
development of vaccines
© Fraunhofer
Tecnical Center for Applied Food Research– TFAL
Utilization of marine ressources (from aquaculture facilities and wild catches) for:
• Development of novel food prototypes from marine ressources
• Development and analyses of dietary supplements for human and animal nutrition
• Development of innovative processing technologies
Example:
Lemonade made with macroalgae
(kiwi/quince flavour)
© Fraunhofer
Facilities at the Fraunhofer EMB
- One-of-a-kind, completely flexibe aquaculture facilities, containing the biggest
landbased marine IMTA in Germany
- 90 m³ outdoor pond for the cultivation of macroalgae
- 6 m³ ponds for mussels
- 3 circular ponds for fish rearing, 3,5 m³ each
- Classical recirculating aquaculture system with modern biofilters as reference
cycle (3 x 3,5 m³)
© Fraunhofer
Aquaculture in Malawi:Joint project of EMB, GMA and University of Malawi
Aquaponics for improving food security and sources of income for native people
Improving reproduction of native fish species (Oreochromis karongae) through
breeding and optimal larval rearing
Low Tech solutions for larval rearing using solar power for regions with insecure
energy supply
© Fraunhofer
Marine Bioeconomy in Schleswig-Holstein –
Activities of EMB
Marine resourcesMariculture
Industry, households
Biorefinery
Agrosystems
Aquaculture
Land
Coast
Sea
• Cellular and molecular biology
technologies for aquaculture
• Production, processing, extraction of
marine raw materials
• Development of novel food and feed
prototypes and ingredients from
marine resources
• Multitrophic aquaculture and novel
aquaculture candidates
© Fraunhofer
Sponsored by the
European Union,
European Fond for
regional development
(EFRE)
THANK YOU
Fraunhofer Institution for Marine Biotechnology (EMB)
Dr. Marina Gebert
Moenkhofer Weg 239 a
D- 23562 Luebeck
Tel.: +49 (0) 451/384 448 - 15
Fax: +49 (0) 451/384 448 - 12
E-Mail:
Internet:
http://www.emb.fraunhofer.de
© Fraunhofer
EU: Submariner (http://www.submariner-project.eu/)
ERA-Net „Marine Biotechnology“
(http://www.marinebiotech.eu/)
National: Nationaler Masterplan Maritime Technologien
(http://www.nmmt.de/)
Nationaler Strategieplan Aquakultur
(http://www.bundesverband-aquakultur.de/aktuelles/nationaler-
strategieplan-aquakultur-veroeffentlicht)
S-H: Masterplan Marine Biotechnologie (bei: http://dsn-online.de)
Associations: DAFA (http://www.dafa.de/)
KNAQ (http://www.knaq-sh.de/)
Bundesverband Aquakultur
(http://www.bundesverbandaquakultur.de/)
Links: