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Choose one correct answer for the following questions:
1. The first microscope was invented by Answer: F.janssen and janssen
1. Leeuwenhoek 2. Hooke 3. F.janssen and janssen 4. Schleiden
2. Fuelgen test is specific for Answer: DNA
1. Proteins 2. RNA 3. Lipids
4. DNA
3. Electrons used in an electron microscope have a wavelength of Answer: 0.05 A
1. 0.05 A 2. 0.1A 3. 0.15 A 4. 0.5 A
4. X-ray crystallography is useful in the study of Answer: Three dimensional structures of proteins
1. Lipd structure 2. Three dimensional structure of proteins 3. Arrangement of proteins 4. Composition of nucleic acids and proteins
5. Blue print for building and running cellular machinery is Answer: DNA
1. RNA 2. DNA 3. mRNA 4. Ribosome
6. Which of the following cannot be grown on artificial culture medium? Answer: TMV
1. E.coli 2. TMV 3. Aspergillus 4. Yeast
7. Process absent in viruses is Answer: Energy liberation
1. Replication 2. Mutation 3. Protein synthesis 4. Energy liberation
8. Life originated in Answer: Water
1. Air 2. Soil 3. Mountains 4. Water
9. Cell theory was put forward by Answer: Schleiden & Schwann
1. Schleiden & Schwann 2. Sutton & Boveri 3. Watson & Crick 4. Darwin & Wallace
10. Smaller cell is Answer: More active metabolically
1. Less active metabolically 2. With smaller nucleus 3. With larger nucleus 4. More active metabolically
11. The three kinds of macromolecules present in the plasma membrane are Answer: Proteins, lipids and carbohydrates
1. RNA, DNA and proteins 2. RNA, proteins and carbohydrates 3. DNA, proteins and lipids 4. Proteins, lipids and carbohydrates
12. Ribosomes in eukaryotes have their origin from Answer: Nucleolus
1. Nucleus 2. Nucleolus 3. Endoplasmic reticulum 4. Mitochondria
13. Starch is commonly stored in Answer: Amyloplast
1. Choroplast 2. Amyloplast 3. Chromoplast 4. Leucoplast
14. Rigidity of plant cell wall is due to Answer: Lignin
1. Pectin 2. Lignin 3. Suberin 4. Cutin
15. Singer and Nicolson's model of plasma membrane differs from Robertson's model in the Answer: Arrangement of proteins
1. Number of lipid layers 2. Arrangement of lipid layers 3. Arrangement of proteins 4. All of the above
16. Naked DNA is found is Answer: Chloroplast
1. Chloroplast 2. Nucleus 3. Lysosome 4. Golgi complex
17. Red blood corpuscles placed in 0.5% sodium chloride solution will show Answer: Bursting
1. Bursting 2. Crenation 3. Plasmolysis4. Turgidity
18. Basal bodies are associated with the formation of Answer: Cilia & flagella
1. Phragmoplast 2. Cilia & flagella 3. Cell plate 4. Kinetochore
19. Cell sap is Answer: Nonliving content of vacuole
1. Living content of cytoplasm2. Nonliving content of cytoplasm 3. Nonliving content of vacuole 4. Living content of vacuole
20. folding of inner mitochondrial membrane are called Answer: Cristae
1. Grana 2. Thylakoids 3. Cristae 4. F0-F1
21. Material exchange through nuclear pore is facilitated by Answer: Protein nucleoplasmin
1. Protein rhodopsin 2. Lamina propria 3. Lipid bilayer 4. Protein nucleoplasmin
22. Membrane bound Krebs cycle’s enzyme is Answer: Succinate dehydrogenase
1. Fumarase 2. Cis-aconitase 3. Succinate dehydrogenase 4. Malate dehydrogenase
23. Which one is different? Answer: chromosomes-mendel
1. Protoplasm-Huxley 2. Cell-Schwann 3. Vitamin-Funk 4. chromosomes-mendel
24. How many mitotic divisions occur in a cell to produce 256 daughter/somatic cells? Answer: 8
1.128 2.64 3.32 4.8
25. Carbohydrates present in cell membrane function in Answer: Cell to cell recognition
1. Attachment of microfilaments 2. Attachment of microtubules 3. Cell to cell recognition
4. Transport of substances
26. Which one is responsible for DNA histone binding? Answer: both i and ii
1. Topoisomerase 2. A=T base abundance 3. Both i and ii 4. Teloisomerase
27. Which is not a type of DNA marker? Answer: RAPD
1. RFLP 2. STR 3. SNP 4. RAPD
28. Which cannot act as inducer? Answer: none
1. Allolactose 2. β galactosidase 3. IPTG 4. None
29. Which one is not used in making genetically modified crops? Answer: artificial plasmid of animals
1. vector based on plant virus 2. various plasmid DNA 3. artificial plasmid of animals 4. natural plasmid of agro bacterium
30. Exons form which fraction of whole human genome Answer: 1.5%
1.50.2% 2.19% 3.75% 4.1.5%
31. Who proposed one gene one enzyme hypothesis? Answer: beadle and tatum
1. Beadle and Tatum 2. Meselson and Stahl 3. Watson and Crick 4. Kornberg
32. Informational molecules of the cell are Answer: both i and ii
1. Protein 2. DNA and RNA 3. Polysaccharides 4. Both i and ii
33. Adapters used in ligation of blunt ended DNA has Answer: one sticky end and one blunt end
1. One sticky end and one blunt end 2. Both sticky ends 3. Both blunt ends 4. None
34. Which protein binds to the unwinded single strand DNA during replication? Answer: SSB
1. Dna B 2. DNA ligase 3. SSB protein4. Primase
35. What is the ratio of absorbance of UV light by pure DNA at 260 nm and 280nm wavelength? Answer: 1.8
1. 1.8 2. 4.8 3. 10.2 4. 7.8
36. Genome of HIV is Answer: ssRNA
1.ss DNA 2.ss RNA 3.ds DNA 4.ds RNA
37. A. tumefaciens causes Answer: Crown gall disease
1. Rust 2. Wart 3. Crown gall disease 4. Hairy root disease
38. An anticoagulant mucopolysaccharide commonly present in animal body is Answer: Heparin
1. Chondroitin sulphate 2. Keratin sulphate 3. Heparin 4. Hyaluronic acid
39. DNA is composed of repeating units of Answer: Deoxyribonucleotides
1. Ribonucleosides 2. Deoxyribonucleosides 3. Ribonucleotides 4. Deoxyribonucleotides
40. Casein present in milk is a Answer: Protein
1. Fat 2. Carbohydrate 3. Protein 4. Bacterium
41. In an experiment, DNA was found to have 31% adenine and 19% guanine. The quantity of cytosine in the said DNA would be Answer: 19%
1.38% 2.31% 3.19% 4.62%
42. The cancerous cells has ______________ type of division Answer: uncontrolled
1. Controlled 2. Sequential 3. Uncontrolled 4. Metastatic
43. The cell cycle is divided into Answer: Interphase & M Phase
1. M & C Phase 2. M & S Phase 3. M & G Phase 4. Interphase & M Phase
44. Why leaves appear green in colour? Answer: Because they reflect green light
1. Because they absorb blue light 2. Because they absorb red light 3. Because they reflect green light 4. All
45. Enzyme that catalyze conversion of glucose to ethanol Answer: Zymase
1. Zymase 2. Invertase 3. Maltase 4. Diastase
46. What is the pH of 0.16 M HCl and 0.072 M phosphoric acid? Answer: 0.8 1. 0.8 2. 11.3 3. 12.9 4. 1.3
47. Eukaryotic mRNA is Answer: Monocistronic
1. Monocistronic 2. Polycistronic 3. Consists SD sequence4. 5' cap is absent
48. Vector used in first cloning experiment in mammalian cell was based on Answer: SV 40
1. SV 40 2. BPV 3. Adenovirus4. Retrovirus
49. Plant material suited for studying mitosis is Answer: root apex
1. Candidate Answers: 2. Shoot apex 3. root apex 4. cork
50. What are G-proteins? Answer: GTP binding proteins
1. GDP Binding Proteins2. GTP binding proteins3. GMP binding proteins 4. GTP transferring protein 5.
51. The process which cannot take place in the absence of viruses is called:
1. Transformation
2. Conjugation
3. Translocation
4. Transduction
52. Pulse Polio programme is organized in our country to:
1. Cure polio
2. Eradicate polio
3. Spread polio
4. None of these
53. Spoilage of food material is prevented in cold storage is due to:
1. Reduced respiration at low temperature
2. Reduced enzyme activity in the food article
3. Reduced enzyme activity in the microbes as well as food article
4. Purified nature of air
54. The sequence of organelles involved in Photorespiration is:
1. Chloroplast MitochondriaPeroxisomes
2. MitochondriaCholoroplastPeroxisome
3. PeroxisomeChloroplastMitochondria
4. Chloroplast PeroxisomeMitochondria
55. Red blood corpuscles placed in 0.5% sodium chloride solution will show:
1. Bursting
2. Crenation
3. Plasmolysis
4. Turgidity
56. Feedback inhibition is caused by blocking of enzyme of the metabolic pathways
by:
1. Accumulated end products
2. Chemical produced by hormones
3. Hormones
4. Competitive inhibition
57. Membrane permeability is controlled by:
1. Na+
2. K+
3. Both (1) and (2)
4 Ca2+
58. Which one of the following is a biodegradable plastic?
1. Leinolic acid
2. Poly hydoxy butyrate
3. Catechol
4. Formamide
59. The rate of evolutionary processes have gone slow mainly because:
1. The earth has become heated
2. There is lack of water on earth surface
3. The environment has become oxidative
4. The environment has become reductive
60. Which Immunoglobulin is found in maximum percentage of total immunoglobulin
in serum?
1. IgG
2. IgM
3. IgD
4. IgA
61. The genetic material of HIV is a:
1. Single stranded DNA
2. Double stranded DNA
3. Single stranded RNA
4. Double stranded RNA
62. The driving force behind evolution is:
1. Sexual reproduction
2. Natural selection
3. Mutation
4. Acquired characters
63. If the frequency of a recessive phenotype is 50% in a large Mendelian population,
what would be frequency of dominant gene?
1. 30%
2. 40%
3. 50%
4. 60%
64. The sequence of bases in tRNA can be represented as:
1. 5’C---ACC3’
2. 5’G---CCA3’
3. 5’U---UCC3’
4. 5’A---CCA3’
65. Which one of the following is one of the three ancestors of common bread wheat?
1. Solanum
2. Zingiber
3. Oryza
4. Aegilops
66. Which light wavelength promotes germination of seed?
1. Red
2. Blue
3. Far red
4. Red and far red
67. Inbreeding leads to sterility mainly because it leads to production of:
1. Recessive homozygous progeny
2. Dominant homozygous progeny
3. Heterozygous progeny
4. Mutant progeny
68. Dehang-Debang Bioreserve is situated in the state:
1. Arunachal Pradesh
2. Assam
3. West Bengal
4. Mijoram
69. ELISA technique is based on:
1. Antigen-Antibody interaction
2. Antigen-Antibody precipitation
3. Antigen –Antibody binding
4. None of these
70. The Red Data Book which lists endangered species is maintained by:
1. WWF
2. UNO
3. WHO
4. IUCN
71. Vaccines are:
1. Attenuated microorganism
2. Inactivated microorganisms
3. Both 1& 2
4. None of the above
72. Among the following which gene is not concerned with induction of cancer?
1. Src
2. Ras
3. P53
4. Actin
73. Which of the following character is controlled by a holandric gene?:
1. Sickle cell anemia
2. Hypertrichosis
3. Blood clotting
4. Phenylketonurea
74. International Rice Research Institute is in:
1 Japan
2. India
3. Phillipines
4. China
75. A protein which is to be degraded in proteosome is tagged with:
1. Polyglycine
2. Polyprolin
3. Ubiquitin
4. Formyl methionine
76. An oligonucleotide DNA sequence tagged with fluorescent tag used to identify
unknown gene by hybridization is termed as:
1. Probe
2. Reporter gene
3. Ligand
4. cDNA
77. The example of X-linked inheritance in human is:
1. Hemophilia
2. Colour blindness
3. Both 1 & 3
4. Hypertrichosis
78. The conversion of pyruvic acid to acetyl Co A requires:
1. Oxidative decarboxylation
2. Oxidative deamination
3. Reductive decarboxylation
4. Reductive deamination
79. In human, Down’s syndrome results due to trisomic condition of chromosome
number:
1.23
2.22
3.21
4.20
80. Lignin, the most abundant organic substance in plants, is an example of
1. Primary metabolite
2. Secondary metabolite
3. Both 1& 2
4. None of these
81. Post translational modification of proteins occurs in:
1. Nucleus
2. Mitochondria
3. Endoplasmic reticulum
4. Glyoxysomes
82. The complementary gene ratio as observed in interaction between two dominant
genes is:
1. 9:7
2. 13:3
3. 9:3:4
4. 15:1
83. Which anticancerous drug has been extracted from Catharanthus roseus?
1. Taxol
2. Vincristine
3. Colchicin
4. Serpentine
84. CDFD, a forensic science laboratory of the Government of India based on
Molecular Biological tools, is located at:
1. New Delhi
2. Hyderabad
3. Madurai
4. Mumbai
85. Covalent bond formation between two atoms takes place by:
1. Transfer of electron from one atom to another
2. One side sharing of electrons
3. Electron sharing by both interacting atom
4. Affinity between two atoms
86. What would be the correct sequence of mRNA if the sequence of bases in template strand is 5’CTTGACTGA 3’?
1. 5’UCAGUCAAG3’
2. 5’GAACUGACU3’
3. 5’TCAGTCAAC3’
4. 5’GAACTGACT3’
87. The bacterial promoter contains sequences rich in:
1. A&T
2. Only A
3. Only T
4. G&C
88. Absorption of water and minerals and fixation of the plant body is the function of:
1. Root system only
2. Vegetative part
3. Shoot system only
4. All of the above
89. A heterozygous tall plant bearing red flower on selfing produced 640 seeds. How
many progeny plants in F2 generation would be pure tall bearing white flowers?
1. 10
2. 20
3. 30
4. 40
90. In human body ectoderm is responsible for the formation of:
1. Lens of eye
2. Nervous system
3. Sweat glands
4. All of the above
91. Human eye is sensitive to wavelength in the range of:
1. 330-760 nanometer
2. 790-800 nanometer
3. 300-360 nanometer
4. 300-390 nanometer
92. Which one the following does not act as a neurotransmitter?
1. Epinephrine
2. Norepinephrine
3. Cortisone
4. Acetylcholoine
93. The catalytic efficiency of two enzymes may be compared by the:
1. Km value
2. pH optimum value
3. Molecular size of enzyme
4. Formation of the product
94. The enzyme used for alcoholic fermentation by yeast is:
1. Maltase
2. Invertase
3. Sucrase
4. Zymase
95. Certain metabolic inhibitors which inhibit carbohydrate translocation are:
1. 2, 4-dinitrophenol and Arsenic
2. Azide iodoacetic acid and Lead
3. Fluoride, Hydrogen cyanide
4. All of the above
96. If guanine (G) in a given DNA is 32%, what would be the amount of adenine (A)?
1. 16%
2. 18%
3. 64%
4. 68%
97. In an inducible operon, the regulator gene produces
1. Inducer
2. Aporepressor
3. Active repressor
4. Co-repressor
98. Histone protein H4 associated with DNA in the chromatin is:
1. Lysine rich
2. Arginine rich
3. Cystein rich
4. Metheonine rich
99. The chromosomes during meiotic division divide during:
1. Anaphase I only
2. Anaphase II only
3. Both Anaphase I and II
4. Diakinesis
100. Which of the following represents the correct order in prophase I of meiosis?
1. Leptotene, zygotene, diplotene, pachytene, diakinesis
2. Leptotene, zygotene, pachytene, diplotene, diakinesis
3. Zygotene, diplotene, pachytene, leptotene, diakinesis
4. Diakinesis, zygotene, diplotene, leptotene, pachytene
