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Medical Cannabis Formulations through University Research 1

Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Page 1: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

Medical Cannabis Formulationsthrough University Research

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Page 2: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Disclaimer

This presentation contains "forward-looking statements" as that term is defined in Section 27A of the Securities Actand Section 21E of the Securities Exchange Act of 1934, as amended. Statements in this presentation which are notpurely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations orintentions regarding the future. Such forward-looking statements include, among other things, use of proceeds and thedevelopment, costs and results of current or future actions and opportunities in the sector. Actual results could differfrom those projected in any forward-looking statements due to numerous factors. Such factors include, among others,the inherent uncertainties associated with new projects and development stage companies, our ability to raise theadditional funding we will need to continue to pursue our exploration and development program, and our ability toretain important members of our management team and attract other qualified personnel.

These forward-looking statements are made as of the date of this news release, and we assume no obligation to updatethe forward-looking statements, or to update the reasons why actual results could differ from those projected in theforward-looking statements. Although we believe that any beliefs, plans, expectations and intentions contained in thispresentation are reasonable, there can be no assurance that any such beliefs, plans, expectations or intentions willprove to be accurate. Investors should consult all of the information set forth herein and should also refer to the riskfactors disclosure outlined in our annual report on Form 10-K for the most recent fiscal year, our quarterly reports onForm 10-Q and other periodic reports filed from time-to-time with the Securities and Exchange Commission.

Page 3: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Overview

CanaQuest Medical Corp is focused on the development of proprietary research andproducts utilizing cannabis oil combined with other botanical and nutraceuticalextracts, including algae oil. Positive data from our research and pre-clinical trials hasdemonstrated that our strategy is achieving meaningful results.

The Company has a number of patentable product formulations developed inconjunction with teams at Western University and the University of Waterloo“Sponsored Research and Product Development Agreements ”.

An extremely experienced US Branding and Marketing team has been selected and our execution plan is in place to rollout our first CBD formulated - science backed products in the United States and for export to Europe.

Our US CBD supplier has the capability to produce medical grade liquid CBD oil that is water soluble, tasteless, with improved bioavailability (ideal for beverages).

Page 4: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Well Positioned in an Emerging Market

Global medicinal cannabis market forecast to reach nearly USD $56 billion by 2024

Collaborations with leading Canadian Research Institutions/Universities to develop specific unique, patented formulated products

Discussions - distribution in Europe for CBD and THC based products - CBD suppliers in Canada and the US

Near term and long-term revenue generation potential; attractive valuation relative to comparable companies

Strategic priorities include – Germany, UK, Brazil, the Caribbean region, Canada

US Branding and Marketing team in place to rollout our first CBD formulated product - scientifically backed

Page 5: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Combined with Strong Strategic Partners

R&DContract

ManufacturingDistribution Retail

Formulations Secured Supply Strategic Partners Patients

Focused on building an IP product

portfolio combining the benefits of

cannabis and other botanicals

Signed Agreements – low cost

medicinal cannabis supply, processing,

packaging and global distribution

Discussions - International

Distribution

Strategic partners enable the Company to focus on product formulations without the need to deploy extensive capital on infrastructure

Page 6: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Provisional Patent Formulation Based On Science

Dr. Steve Laviolette, BSc, PhD, University of Western Ontario

Ph.D. University of Toronto

B.Sc. University of Toronto

Addiction Research Group

Department of Anatomy & Cell Biology

Department of Psychiatry & Canadian

Institute for Military and Veterans

Health Research

Quotes by Dr. Steve Laviolette

“The clinical implications and commercial potential for this product are highly significant.”

“Furthermore, since cannabis is commonly prescribed for a host of ailments, including pain, nausea, glaucoma, multiple sclerosis, osteoarthritis, our formulation will again be hugely significant for the non-mental health patient sectors as well.”

“We are making rapid progress on this project and are already working out the precise molecular mechanisms underlying modes of action of this unique formulation. I was amazed at how effective this formulation is.”

Research Interests

Dr. Laviolette's research interests explore the interface between neurobiology, psychology and emotion by using an integrative combination of in vivo neuronal electrophysiology and behavioral neuropharmacology. At the general level, Dr. Laviolette is interested in exploring the neurobiological mechanisms that control how the brain processes emotionally salient information and how disturbances in these basic neural processes may lead to disorders such as addiction and schizophrenia.

Page 7: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Cancer Research - ongoing

Dr. Jonathan Blay, PhD, University of Waterloo

• State-of-the-art cancer research laboratory in Canada's most innovative university.

• Leading expert in discovery of novel cancer therapeutics and their clinical use and pain management.

• Focused team of 8 team members with diverse skills and clinical backgrounds.

• Perspective informed by longstanding interactions with medical schools.

• Instrumentation to allow studies all the way from molecular to in vivo assessments.

• Established track through to veterinary and human testing protocols.

• Fellow of the Royal Society of Medicine

• Professor of Pharmacy (Waterloo)

• Professor of Pathology (Dalhousie)

• Senior Scientist of the Beatrice Hunter Cancer Research Institute (BHCRI)

• Member of the Institute for Comparative Cancer Investigation

• Member of the Canadian Association of Pharmacists in Oncology (CAPhO)

Page 8: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Provisional Patent Formulation Based On Science

DHA/CQBT - Natural Health Product

Formulation

Recreational or Medical Cannabis use: THC exposure – prevents negative side effects

Side Effects

THC acute exposure

Side Effects

THC long term exposure

Anxiety

Addiction Depression Schizophrenia PTSD

Memory loss

Mentanine™

CQBT – food grade approved botanicals

Pain

Page 9: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Provisional Patent Formulation Based On Science

CBD/DHA/CQTB - Oil Formulation

Medical cannabis formulation with enhanced efficacy treats:

Anxiety

Addiction

Depression

Schizophrenia

PTSDNausea

Mentrium™

CQBT – proprietary botanicals

Pain

Page 10: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Patentable Formulation Based On Science

THC/DHA/CQTB - Oil Formulations

Medical Cannabis use: treats ailments such as anxiety, depression, memory loss, psychosis, and other mental disorders without negative side effects:

Side Effects

THC acute exposure

Side Effects

THC long term exposure

Anxiety

Addiction Depression Schizophrenia PTSD

Paranoia

Mentabinol™

CQBT – Food grade approved botanicals

Pain

Page 11: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Target Markets

Based on studies, research and anecdotal data, CanaQuest recognizes that cannabis is very effective for mental and physical ailments. CanaQuest’s target markets are as follows:

• Past patients/consumers of cannabis (THC) who took it for their respective ailment and had an acute negative affect (30% + of the market). Our formulations increase the comfort level of THC treatment and provides the opportunity to bring back past medicinal cannabis patients and consumers

• New cannabis patients/consumers who want THC based cannabis treatment and, who are prone to acute negative psychotic effects of high consumption of THC

• Cannabis patients/consumers who want safe THC/CBD based cannabis treatment

for their respective ailments that is backed by science

Page 12: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Page 13: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Natural Health Products - Manufacturing and Distribution

• Canadian GMP manufacturer of powders, soft gels, tablets and capsules with enhanced

bioavailability technology and international distribution

• Discussions regarding contract manufacturing

GMP/ Pharmaceutical

Company (Canada)

• Organizing human trials

Licensed Cannabis

Clinics and Health

Stores

• Direct sales and LP distribution network - sales of medical formulations to patients

• Sales Licence - final review stage and e-commerce ready for implementation

Online Sales - Health

Canada Licence

• US Branding/Marketing Team in place – distribution USA and Europe

• Discussions – distribution of CBD based formulations in Europe through pharmacies

Global Sales

and Distribution

• USA GMP manufacturer, - CBD producer and medical product formulator

• Discussions regarding international sales and distribution

CBD Supplier

GMP Manufacturer

(USA)

Page 14: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Formulation Product Description

Packaged Product

Purchase Order

Delivery

Natural Health Products Sales Structure

Page 15: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Formulation Product Description

Packaged Product

Request by Physician

Prescription

Medical Sales Structure – Licence Without Possession

Page 16: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Management, Board and Advisory Team

Richard Rusiniak, Co-Founder, CEO

Co-Founder, CEO

Over 30 years of management, design and process experience. Co-founder

and former President, CFO, and CTO of Cymat Corp (TSX: CYM) with a

market valuation over $150 million upon his resignation in 2002. Negotiated

an Aluminum Foam Manufacturing license with Alcan International Ltd., and

successfully commercialized the technology. Completed a $10 Million

technology development program with Industry Canada (TPC). Participated in

the completion of $25 million in financing with financial institutions. From 1978

to 1988, he was project manager with Long Manufacturing, as well as The

Ontario Research Foundation (Ortech).

Paul Ramsay, BBA

Co-Founder & President

Over 25 years of business development and management experience. Co-

founder and former CEO and VP Business Development of Cymat Corp,

(TSX: CYM) with a market valuation over $150 million upon his resignation in

2002. Was instrumental in securing the Stabilized Aluminum Foam (SAF)

license from Alcan International Ltd. Completed a $10 Million technology

development program with Industry Canada (TPC). Participated in the

completion of $25 million in financing with financial institutions. Obtained

Bachelor of Business Administration "BBA" from St. Francis Xavier University,

Nova Scotia, Canada.

Ross Eastley

CFO

Over 30 years of accounting and CFO experience in both private and public

sector organizations. Former CEO for the Canadian Society of Immigration

Consultants (CSIC) from 2006 - 2009. Mr. Eastley reported to a nine-member

Board, responsible for strategic planning, corporate communications, initial

regulatory functions and management of legal processes. Former V

P/Controller for Brandon University.

Paul RamsayChairman, Director

Richard RusiniakDirector

Ross Eastley

Secretary, Director

P. Blair Mullin BA, BBA

Director

Cameron McDonald BSc,

MBA, CFA

Director

Leadership Team Board of Directors

R & D Collaborators

Dr. Steven Laviolette BSc, PhDDept. of Anatomy & Cell Biology, Dept. of Psychiatry, University of Western OntarioDr. Laviolette's investigations have focused on nicotine and opiates, highlyaddictive substances that act on pathways in the brain that control reward,motivation and learning. His research group has characterized and identifiedspecific regions in the mammalian brain that control the 'switch' from the non-addicted state, to the addicted state following exposure to drugs of abuse. Thegoal of his research is to determine how specific cannabis-derived phytochemicalcompounds such as delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD) andother phytochemical and/or terpenoid compounds derived from cannabis, mayserve to ameliorate symptoms and/or serve as potential pharmacotherapies forschizophrenia, anxiety, depression and post-traumatic stress disorder.

Dr. Jonathan Blay PhD, FRSB, FIBMS, Csci, CBiolProfessor of Pharmacy, University of WaterlooProfessor of Pathology, Dalhousie UniversityDr. Blay's research group applies a range of techniques in molecular and cellularbiology to understand cell behavior and how the action of existing anticancerdrugs are affected by the unique physiology of the cancer. The goal is toperform fundamental cancer-related research on botanical oils and theirconstituents which will carry out studies relating to the cellular safety andknown cancer-related potential of components within the oils.

Page 17: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Next Steps

Sign agreements with Licensed Producers/Distributors to sell medicinal cannabis domestically and Internationally2

3

4

5

6

7

8

Supply CBD and THC formulated products from Licenced Producers for sales in Europe

Implement human trial feasibility studies to further support our research and animal clinical trial

results

Secure licence from Health Canada for Purchase/Sale, Import/Export - the Cannabis Act (non-possession)

Secure funding and apply to list on the Canadian Securities Exchange (CSE) – dual listing

Build brand awareness with selected experienced Brand/Marketing team

Ongoing support to Universities for additional scientific product development

File Additional Provisional Patent Product Applications

1

Page 18: Medical Cannabis Formulations through University Research · 19/07/2019  · Was instrumental in securing the Stabilized Aluminum Foam (SAF) license from Alcan International Ltd

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Thank you

Contact Information

CanaQuest Medical Corp

37 - 4120 Ridgeway Drive

Mississauga, Ontario L5L 5S9

www.canaquest.com

Paul Ramsay, President

Ph.: 416-704-3040

[email protected]