Common Drugs and Its Antidotes Acetaminophen(Paracetamol)

N-acetylecysteineSalicylates

Alkalinize urine, DialysisAnticholinesterase (Prostigmin)

Atropine SulfateAnticholinergic (At. SO4)

ProstigminBeta Blockers

GlucagonDigitalis

DigibindExtrapyramidal Symptoms

BenadrylIron (Ferrous Sulfate)

DeferoxamineLead

Penicillamine, DimercaprolCyanide

Nitride, HydroxocobalamineMethemoglobin

Methylene blueCarbon Monoxide

100% Oxygen, Hyperbaric O2Methanol (Antifreeze)

FomepizoleOpioids and Narcotic analgesics

Narcan (Naloxone)Benzodiazepines

Flumazenil (Romazicon)TCA’s

NaHCO3Heparin

Protamine SulfateCoumadin

Vitamin KThrombolytics

Aminocaproic acid (Amicar)Lithium Carbonate

Sodium BicarbonateCalcium Channel Blockers

CalciumMagnesium Sulfate

Calcium gluconateDopamine

PhentolamineSuccinylcholine

Respiratory SupportPotassium

Insulin + Glucose, Kayexalate

Normal ValuesABG

Ph 7.35 - 7.45

PCO2 35 – 45 mm Hg

HCO3 22 – 26 mEq/ml

PO2 80 – 100 mm Hg

SaO2 93 – 100%

RBC

Male 4.5 - 6.2 million/ cubic mm

Female 4.0 - 5.5 million/cubic mm

WBC

5,000 - 10,000/ cubic mm

Platelets

150,000 - 450,000/ cubic mm

Hgb

Male 14 - 16.0 g/dL Female 12 - 14 g/ dL

Hct

Male 42 - 52% Female 35 - 47%

PT (Warfarin/ Coumadin)

12-16 secs

Should be 1.5 to 2 times the Normal

PTT/ APTT (Heparin)

20-36 secs / 30-45 secs

Should be 1.5 to 2.5 times the Normal

INR

2 – 3 Standard Warfarin therapy

3 – 4.5 High dose Warfarin therapy

2-3 Atrial fibrillation, DVT and Pulmonary embolism

2.5-3.5 Prosthetic heart valves

Bleeding Time

3 - 7 mins.

Electrolytes

K 3.5 - 5.0 mEq/ L

Mg 1.6 - 2.6 mEq/ L

Ph 2.7 - 4.5 mEq/ L

Na 135 - 145 mEq/ L

Cl 98-107 mEq/ L

Ca 8.0 - 10 mg/dL or Ca 4.5 – 5.5 mEq/L

Blood Sugar

80-120 mg/dL

Glycosylated Hgb (glycohemoglobin)

less than 7.5% Good

7.6 - 8.9% Fair

greater than 9% Poor

Vanillylmandelic Acid (VMA)

0.7 - 6.8 mg/24 hrs

GFR

125 ml/min

Creatinine

0.6-1.2 mg/dL

BUN

10 – 20 mg/dL

UO

Adult: 30 cc/hr and 720 cc/24 hours

Pedia: 2cc/ kg/ hr

AST/ ALT

5-40 IU/L

Ammonia

9-33 µmol/L

35-65 mcg/ dl

Albumin

3 - 5 g/dL

Amylase

25-151 units/ L

Lipase

10-140 units/ L

Bilirubin (Total)

less than 1.5 mg/ dL

Pulmonary capillary mean wedge pressure

4-12 mmHg

Central Venous Pressure

2-6 mmHg

Plasma Osmolality

280-300 mOsm/kg

Serum Alcohol

LEGAL .08 - .10

TOXIC! grater than 0.15 (50mg/100cc of blood)

greater than 8%

ICP

4-15 mmHg / 80-100 mmH20