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[Type text] 1 Mediterranean 8:00 - 9:30 WORKSHOP 1 W1. An introduction to ClinFIT: An emerging ICF-based tool for clinical assessment and reporting of patient functioning in rehabilitation Coordinator: Gerold Stucki (Switzerland) W1- 1. Gerold Stucki (Switzerland) W1- 2. Melissa Selb (Switzerland) W1- 3. Aydan Oral (Turkey) W1- 4. Francesca Gimigliano (Italy) For the clinical assessment and reporting of patient functioning, rehabilitation professionals rely on a wide range of suitable data collection tools. However, a universal and simple-to-use clinical data collection tool that can be tailored to the needs of clinicians all over the world, across a range of settings and patient groups is warranted. Ideally, this tool is based on the International Classification of of Functioning, Disability and Health (ICF). As highlighted by WHO's “Rehabilitation 2030: A Call for Action” the ICF and its implementation in health systems is fundamental for strengthening rehabilitation in the 21st century. An emerging tool for ICF-based data collection in rehabilitation is ClinFIT – Clinical Functioning Information Tool. ClinFIT can be tailored for use across countries and a range of rehabilitation services, and can fulfil the specifications of national quality management systems for rehabilitation, meet the requirements of national and international standards for rehabilitation interventions and services provision, and be used in research. Continuous improvement is facilitated through feedback from clinicians and the scientific community as a whole. In this workshop, we will introduce the conceptualization of ClinFIT, detail the building blocks and guiding principles, and give participants insight on how ClinFIT can be implemented in Europe. 9:30 - 11:30 WORKSHOP 2 W2. Current trends in evaluation and conservative treatment of children with idiopathic scoliosis and other spinal deformities Coordinator: Stefano Negrini (Italy), Vesna Zivkovic (Serbia) W2-1. Vesna Zivkovic (Serbia): Introduction W2-2. Stefano Negrini (Italy): Guidelines for rehabilitation of patients with idiopathic scoliosis W2-3. Vesna Zivkovic (Serbia): Evaluation of idiopathic scoliosis patients W2-4. Nikola Jevtic (Serbia): The principles of ISST Schroth therapy according to Asklepios-Katharina Schroth W2-5. Michele Romano (Italy): Video from the SEAS exercises approach W2-6. Ozden Taskiran (Turkey): Bracing AIS: different braces and schools The treatment and prevention of progression of idiopathic scoliosis and other spinal deformities in children is a challenge for the therapeutic team. This workshop aims to examine the modern assessment of these children and provide new scientific evidence of conservative treatment, including

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Page 1: Mediterranean · As highlighted by WHO's “Rehabilitation 2030: A Call for Action” the ICF and its implementation in health systems is fundamental for strengthening rehabilitation

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Mediterranean 8:00 - 9:30 WORKSHOP 1 W1. An introduction to ClinFIT: An emerging ICF-based tool for clinical assessment and reporting of patient functioning in rehabilitation Coordinator: Gerold Stucki (Switzerland) W1- 1. Gerold Stucki (Switzerland) W1- 2. Melissa Selb (Switzerland) W1- 3. Aydan Oral (Turkey) W1- 4. Francesca Gimigliano (Italy)

For the clinical assessment and reporting of patient functioning, rehabilitation professionals rely on a wide range of suitable data collection tools. However, a universal and simple-to-use clinical data collection tool that can be tailored to the needs of clinicians all over the world, across a range of settings and patient groups is warranted. Ideally, this tool is based on the International Classification of of Functioning, Disability and Health (ICF). As highlighted by WHO's “Rehabilitation 2030: A Call for Action” the ICF and its implementation in health systems is fundamental for strengthening rehabilitation in the 21st century. An emerging tool for ICF-based data collection in rehabilitation is ClinFIT – Clinical Functioning Information Tool. ClinFIT can be tailored for use across countries and a range of rehabilitation services, and can fulfil the specifications of national quality management systems for rehabilitation, meet the requirements of national and international standards for rehabilitation interventions and services provision, and be used in research. Continuous improvement is facilitated through feedback from clinicians and the scientific community as a whole. In this workshop, we will introduce the conceptualization of ClinFIT, detail the building blocks and guiding principles, and give participants insight on how ClinFIT can be implemented in Europe. 9:30 - 11:30 WORKSHOP 2 W2. Current trends in evaluation and conservative treatment of children with idiopathic scoliosis and other spinal deformities Coordinator: Stefano Negrini (Italy), Vesna Zivkovic (Serbia) W2-1. Vesna Zivkovic (Serbia): Introduction W2-2. Stefano Negrini (Italy): Guidelines for rehabilitation of patients with idiopathic scoliosis W2-3. Vesna Zivkovic (Serbia): Evaluation of idiopathic scoliosis patients W2-4. Nikola Jevtic (Serbia): The principles of ISST Schroth therapy according to Asklepios-Katharina Schroth W2-5. Michele Romano (Italy): Video from the SEAS exercises approach W2-6. Ozden Taskiran (Turkey): Bracing AIS: different braces and schools The treatment and prevention of progression of idiopathic scoliosis and other spinal deformities in children is a challenge for the therapeutic team. This workshop aims to examine the modern assessment of these children and provide new scientific evidence of conservative treatment, including

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physiotherapy scoliosis-specific exercises (PSSE) and brace. Four oral presentations are planned (15 minutes each). The first oral presentation will be devoted to the contemporary evaluation of children with idiopathic scoliosis and other spinal deformities, based on the 2016 SOSORT guidelines. An evidence-based bracing approach for adolescents with idiopathic scoliosis will be the topic of the second presentation. The last two presentations will focus on PSSE, mainly Schroth and SEAS (Scientific Exercises Approach to Scoliosis) method. The oral lectures will be followed by a practical demonstration of Schroth and SEAS exercises in children with scoliosis. Expected results: After the workshop, participants are expected to increase their knowledge about PSSE and brace and their importance in the treatment of children with spinal deformities. Cost: 30 € 11:30 - 12:00 BREAK 12:00 - 14:00 WORKSHOP 3 W3. Insight into UEMS-PRM efforts to foster ICF-supported clinical quality management in rehabilitation in Europe Coordinator: Gerold Stucki (Switzerland) W3- 1. Mauro Zampolini (Italy) W3- 2. Melissa Selb (Switzerland) W3- 3. Carlotte Kiekens (Italy) W3- 4. Mark Delargy (Ireland) W3- 5. Gerold Stucki (Switzerland) Effectiveness in rehabilitation is achieved when desired clinical outcomes, i.e. optimal functioning, are reached. The reference system for the standardized reporting of functioning outcomes is the International Classification of Functioning, Disability and Health (ICF), including in clinical quality management in rehabilitation (CQM-R). To foster ICF implementation in CQM-R, the Physical and Rehabilitation Medicine Section and Board of the European Union of Medical Specialists (UEMS-PRM) approved an ICF implementation plan that includes identifying the types of currently provided rehabilitation services in Europe, implementing clinical assessment schedules (CLASs) for each of these service types (i.e. what aspects of functioning to document, for whom and when), and developing and promoting the intricate and multi-professional intervention scheme called “Individual Rehabilitation Project” (IRP) modelled after the one developed in Italy. The objective of this workshop is to familiarize the participants with the essential elements of the UEMS-PRM efforts (i.e. European framework of rehabilitation service types and corresponding CLASs and IRP) and concrete implementation activities. Participants will also have an opportunity to provide valuable expert input on how implementation of the European Framework, CLASs and IRP can used in the continuous improvement of rehabilitation service provision in their respective countries and in Europe in general. 14:00 - 15:00 BREAK

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Adriatic 8:00 - 9:30 WORKSHOP 4 W4. Manual medicine in temporo-mandibular disorders Coordinator: Enrique Varela-Donoso (Spain) W4- 1. Enrique Varela-Donoso (Spain) This workshop is especially aimed at PRM physicians interested in the management, assessment and manual treatment of subjects suffering from temporo-mandibular disorders (TMD) Manual medicine is an expertice often used by physicians to relieve, especially, musculoskeletal conditions. TMD are very frequent in the daily consultation of physical medicine and rehabilitation, limiting the activity and participation of the subjects who suffer it. In addition to the problems caused in this area, they are also and very often cause other symptoms such as headaches, cervicalgias and other processes. By means of a precise knowledge of the biomechanics of the referred joint and its muscle-tendon and ligament relationships, as well as adequate manual assessment and patient management, it is possible by different manual techniques of treatment, correction and alleviation of such disorders. With the purpose of fostering the participation of all the attendance, the workshop will include demos of assessment and treatment among participants. Table of contents: Brief biomechanic introduction of the temporo-mandibular Joint (TMJ) Brief introduction to clinical assessment of the TMJ Treatment techniques for TMD (soft tissue techniques and structural techniques Demonstration

Cost: 30 € 9:30 - 11:30 WORKSHOP 5 W5. Important Medical Considerations and Challenges in Oncology Rehabilitation Coordinator: Tatjana Zdravkovic (Canada) The lectures will include the following topics: W5- 1. Tatjana Zdravkovic (Canada): Chemo induced Peripheral neuropathy W5- 2. Patrice Patrice de Peiza (Canada): Lymphedema W5- 3. Jan Park Dorsay (Canada): Bone health and bone stability W5- 4. Dr. George Francis (Canada): Radiation induced changes W5- 5. Dr. David Harvey (Canada): Post mastectomy pain syndrome W5- 6. Lori J. Bernstein (Canada): Cancer related cognitive changes W5 -7. Tatjana Zdravkovic (Canada): Chemo induced cardiomyopathy

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As the need for the oncology rehabilitation is expected to drastically increase in the coming years, the purpose of the workshop is to review common medical conditions people with cancer may experience. Rehabilitation teams need to have knowledge to assess these medical conditions, manage them, and offer rehabilitation interventions to improve function and quality of life. Cost: 30 € 11:30 - 12:00 BREAK 12:00 - 14:00 WORKSHOP 6 W6. Models of Oncology Rehabilitation Care and Exercise as a Treatment in Patient with Cancer Coordinator: David Harvey (Canada) The lectures will include the following topics: W6- 1. David Harvey, David Lagelier, Jan Park Dorsay (Canada): Models of oncology rehabilitation care W6 - 2. Lori J. Bernstein, Patrice De Peiza, OrenCheifetz (Canada): Exercise effect on fatigue, sleep, mood, healthy BMI in patients with cancer W6 - 3. Oren Cheifetz, David Lagelier (Canada): Exercise prescription for patients with cancer, including palliative care setting With the review of our own and international experiences in Oncology Rehabilitation, the audience will become familiar with current models in oncology rehabilitation at inpatient, outpatient, and community settings. Presentation of the latest evidence and rehabilitation interventions related to the effect of exercise on fatigue, sleep, mood, healthy BMI in patients with cancer. Participants will receive practical guidance and evidence informed information to use exercise in patients with cancer at different stages of cancer, from diagnosis, to treatment, surveillance, extensive disease and palliation. Cost: 30 € 14:00 - 15:00 BREAK

Baltic 8:00 - 9:30 WORKSHOP 7 W7.Gait analyses in multiple sclerosis, and time series Coordinator: Hilal Keklicek (PhD (Biomechanics), PT), Halit Selcuk, MSc, PT (Turkey) W7-1. Hilal Keklicek (Turkey): The multifaceted nature of the human walk W7- 2. Halit Selcuk (Turkey): Basic terminology, kinetics- kinematics W7- 3. Hilal Keklicek (Turkey): Gait; Chaos and order W7- 4. Hilal Keklicek (Turkey): The ability of variability at walk, autocorrelation and fractality W7- 5. Hilal Keklicek (Turkey): Gait dynamics and postural stability W7- 6. Hilal Keklicek (Turkey): Gait analyzing methods

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W7- 7. Hilal Keklicek (Turkey): Gait problems and cortical involvement in multiple sclerosis - Kinetics deviations, Muscle impairment, Postural instability related gait deviations,

Pyramidal or/and extrapyramidal impairment, Cortical impairment, Ground reaction, Fatigue, Cognitive impairment

W7- 8. Hilal Keklicek (Turkey): Choosing the target focused gait analyzing method at correct time: We need who? W7- 9. Hilal Keklicek (Turkey): Interpretation of clinical findings; and choosing the right treatment strategy. 9:30 - 11:30 WORKSHOP 8 W8. Assessment of cardiac patient status and accident risk during rehabilitation Coordinator: Milica Lazovic (Serbia) W8 -1. Milica Lazovic (Serbia): Importance of functional assessment of cardiac patients W8 -2. Dejan Spirovski (Serbia): Differences between a diagnostic test and a test that assesses functional capacity W8 -3. Mojsije Andjic (Serbia): Principles of Exercise Testing and Interpretation W8 -4. Dejan Spiroski (Serbia): Cardiopulmonary exercise testing (CPET) in the direct assessment of the intensity of physical exertion W8 -5. Dejan Spiroski (Serbia), Milica Lazovic (Serbia), Mojsije Andjic (Serbia): The case for using an exercise tolerance test. The intensity of exercise training (ET) is a key component of the rehabilitation of cardiac patients because it is directly related to the degree of improvement of functional capacity but also to the risk of adverse events during exercise. It is extremely important to understand the difference between a diagnostic test and a test that assesses functional capacity. Patients who are enrolled in a rehabilitation program already have mostly confirmed heart disease and exercise testing is performed under therapy as it also serves as a temporary assessment of functional capacity under optimal medication therapy. Alternatively prescribing rehabilitation to a heart rate that is 20 rpm higher than resting heart rate, precisely reduces the effectiveness of achieving adequate rehabilitation because it is not based on a precise and individual assessment. ET intensity can be represented as % peak heart rate, HR peak, % HRR, % peak WL peak, or Borg scale which are indirect indicators of functional status. The limitations of these parameters with respect to VO2 peak have been shown because they are not always consistent with the VO2 values . Therefore, the application of cardiopulmonary exercise testing (CPET) is the gold standard in the direct assessment of the intensity of physical exertion because it gives us VO2 as a measure of oxygen transport and utilization at certain levels of load (especially in patients with heart failure). Results Expected: A good risk assessment of cardiovascular events results in a small number of complications during ET. In a cardiac rehabilitation program, the incidence of complications requiring resuscitation is an average of 1 in 62,000 hours of ET. ECG telemetry is required for patients with left ventricular EF <30%, an increase in the incidence of arrhythmias during FT, in severe ACD, and in patients with a defibrillator. Cost: 20 €

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11:30 - 12:00 BREAK 12:00 - 14:00 WORKSHOP 9 W9. Diagnostic Ultrasound in PRM Coordinator: Ozcakar Levent (Turkey) W9 - 1. Nikos Barotsis (Greece): Musculoskeletal US in PRM W9 - 2. Kamal Mezian (Czech Republic): Imaging for nerve pathologies W9 - 3. Levent Özçakar (Turkey): STAR: A golden formula in sarcopenia Cost: 20 € 14:00 - 15:00 BREAK

Aegean 8:00 - 9:30 WORKSHOP 10 W10. HIV: A New Chronic Disease Population Coordinator: David Burke (USA) W10- 1. David Burke (USA) Approximately 36.9 million people worldwide are living with human immunodeficiency virus (HIV). Younger people living with HIV (PLHIV) have an increased risk of cardiovascular disease (CVD) and an increased risk of ischemic stroke, heart failure, and peripheral artery disease (PAD). We recently found patients admitted to an inpatient rehabilitation facility (IRF) with a diagnosis of HIV demonstrated a reduced rate of functional recovery per hospital day as compared to those who were HIV negative. The study also revealed that HIV positive patients were younger at admission, which warrants a need for active surveillance for those living with HIV. Due to the increased life expectancy of HIV patients, we believe IRFs will see an increased rise in census as a result from the HIV-related inflammation and cardiovascular risk factors. Lectures discussing the epidemiology, neurological and musculoskeletal effects of HIV. The topics will include: (1) global views (2) lifespan (3) medicine (4) cognition (5) affect (6) PNS (7) pain (8) mobility, and (9) treatment plans. Results Expected: Increased knowledge of the effect of HIV on the risk of stroke and the means by which professionals in Rehabilitation Medicine can treat the neurological and musculoskeletal symptoms of this newly chronic disease. Cost: 20 € 9:30 - 11:30 WORKSHOP 11

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W11. Specifics of pediatric electrodiagnostics Coordinator: Gulseren Akyuz (Turkey), Dejan Nikolić (Serbia) W11 - 1. Gulseren Akyuz (Turkey): How different is pediatric EMG? Why do we need it? W11- 2. Ivana Petronic- Markovic (Serbia): Electrodiagnostic approach of external annal sfincter in children with anorectal anomalies W11 - 3. Dejan Nikolic (Serbia): Electrodiagnostic elements of most frequent myopathies in children W11 - 4. Evrim Karadag-Saygi (Turkey): Electrodiagnostic evaluation of hypotonic (floppy) baby Evaluation of electromyography (EMG) and nerve conduction velocities (NCV) in diagnosis, differential diagnosis and treatment outcome of neuromuscular diseases in pediatric population. Furthermore, introduction with specifics and pitfalls in electrodiagnostics in pediatric population. Power point presentation and hands on active interaction. Results expected: Able to perform basic EMG and NCV examination. Able to recognize the type of neuromuscular lesion (polyneuropathy, myopathy and neurogenic

lesion). Able to recognize which nerves are affected (motor, sensory, mixed). Able to recognize acute, subacute and chronic lesion. Able to understand the degree of neurogenic lesion and potential for recovery.

Cost: 30 € 11:30 - 12:00 BREAK 12:00 - 14:00 WORKSHOP 12 W12. Mesotherapy in spine pain Coordinator: Calogero Foti (Italy) W12- 1. Calogero Foti (Italy): History and Literature review Anatomy and Mechanisms of action Method, Instrumentation and Drugs Indications, Contraindications, Adverse reactions

Cost: 80 € 14:00 - 15:00 BREAK

Danube 8:00 - 9:30 WORKSHOP 13

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W13. Evaluation and assessment of osteoarthritic hand Coordinator: Fitnat Dincer (Turkey) W13- 1. Fitnat Dincer (Turkey) In this workshop diagnosis, evaluation, physical examination and the types of osteoarthritic hand will be stressed and also diagnosis of hand osteoarthritis will be emphasized on the basis of Evidence Based Medicine. Diagnosis and Evaluation of Osteoarthritic Hand will be discussed on the basis of evidence based medicine. Also on a Hand model, all the joints of the hand will be shown and the joints that are essentially and especially involved in Hand OA will be demonstrated. Results expected: At the end of this workshop; knowledge will be gained about, evaluation, physical examination and the types of osteoarthritic hand and also diagnosis of hand osteoarthritis on the basis of Evidence Based Medicine. Cost: 10 € 9:30 - 11:30 WORKSHOP 14 W14. Advances in extracorporeal shock wave therapy Coordinator: Elena Ilieva (Bulgaria) W14 -1. Elena Ilieva (Bulgaria): Extracorporeal shock wave therapy – principles, indications, evidence about effectiveness in standard and some of the exceptional indications W14 -2. Nikolaos Barotsis (Greece): Optimizing ESWT with ultrasound guidance The aim is to provide the necessary theoretical knowledge and practical skills for the effective and safe use of radial and focused ESWT. The theoretical part will be followed by demonstration and hands-on practice. Methods used: Theoretical part, demonstration, hands-on Results expected: By the end of the workshop the participants will be fully aware regarding the physical and biological principles, standard indications and evidence about the effectiveness of ESWT in different disorders. They will become familiar with the new fields of application (spasticity, osteoarthritis). During the hands-on session the participants will have the opportunity to practice on different types of equipment under the guidance of the workshop instructors. 11:30 - 12:00 BREAK 12:00 - 14:00 WORKSHOP 15 W15. Neurophysiological background of physical therapies Cordinator: Roberto Casale (Italy) W15 -1. Roberto Casale (Italy):

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Basic in neurophysiology: receptors; afferent fibers; segmental and suprasegmental pathways; descending control

Physical modalities: Mechanical; electrical; thermal and LASER stimulation How physical therapies interact with and within the nervous system How, when and where to apply physical therapies in practice Real and “defensive” contraindication.

Cost: 80 € 14:00 - 15:00 BREAK

Sava 8:00 - 9:30 WORKSHOP 16 W16. Neurogenic bladder dysfunction, urodynamics’ interpretation Coordinator: Christina-Anastasia Rapidi (Greece) W16- 1. Christina-Anastasia Rapidi (Greece) Voiding dysfunction following nervous system lesions has a tremendous impact on the quality of life of people with disabilities. Physical & Rehabilitation Medicine physicians and all the members of the rehabilitation team are involved in the management of neurogenic bladder and bowel dysfunction. The appropriated and successful therapeutic management relies on goals setting accepted by the rehab team (patient being part of the team) taking into consideration the medical history, clinical examination, specialized clinical tests, imaging of urinary tract, and urodynamic studies. Urodynamics are planned according to the specific clinical data and their interpretation is a part of the rehabilitation procedure. The workshop will be interactive and presenters, scholiasts, and the audience will participate in fruitful discussions. Clinical data of cases will be presented and then their urodynamics data, and vice versa. In the end of the workshop participants will be able to: decide the appropriate timing of performing urodynamics interpret urodynamic findings and clinical data on a clear neurogenic dysfunction of urination of a

specific patient with specific therapeutic rehabilitation goals Cost: 20 € 9:30 - 11:30 WORKSHOP 17 W17. Advanced technologies in Rehabilitation Medicine Coordinator: Enrique Varela-Donoso (Spain) W17 -1. Enrique Varela-Donoso (Spain) W17 -2. Cristina Herrera (Spain) W17 -3. Alfonso Oltra (Spain)

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This workshop is especially aimed at Physical and Rehabilitation Medicine (PRM) physicians who are interested in gaining knowledge of scientific & technical advances in the field of clinical biomechanical assessment of musculoskeletal and/or neurological disorders.The Institute of Biomechanics of Valencia (IBV), as a reference institution at European level in this field, will introduce attendants the theoretical and practical framework about how this discipline is currently being applied to improve patient's management when it comes to evaluation and rehabilitation of locomotor impairments, including those related to chronicity and healthy ageing. This workshop also intends to provide a dissemination platform for significant outcomes achieved by IBV & ESPRM under the context of different European projects, highlighting the results of the Brain4Train project (for virtual reality in stroke patient's treatment), supported ERASMUS+ Program. TABLE OF CONTENTS Section 1 IBV presentation and main focus areas related to PRM. Biomechanical assessment in the Rehabilitation Field: utility and examples of use. Different approaches for the analysis of gait&risk of falling at IBV: AMHPlus and FallSkip. Virtual Reality in the rehabilitation of stroke: results of the Brain4Train project. Brief information about other ongoing projects related: TEACH project.

Section 2 Demo, including the use of IBV's devices for biomechanical assessment of different functions. Conclusions and further information.

Cost: 10 € 11:30 - 12:00 BREAK 12:00 - 14:00 WORKSHOP 18 W18. Non-psychiatric multi-disciplinary rehabilitation of patients with severe mental illnesses Coordinator: Iuly Treger (Israel) W18- 1. Iuly Treger (Israel) Patients with severe mental illnesses (SMI) have reduced life-expectancy and increased risk for physical disorders. Although SMI patients are entitled to the same standards-of-care as the rest of the population, the rates of undiagnosed and untreated medical illnesses are higher. Many SMI patients do not get a non-psychiatric multi-disciplinary rehabilitation due to stigma regarding their rehabilitation potential and motivation. Our PRM department is situated inside a big general hospital, and we have a great experience in subacute in-patient PRM treatment of SMI patients after injuries and diseases. The multidisciplinary staff, including PRM doctors, psychiatrists, psychologists and other, use a special approaches and techniques to succeed in the rehabilitation program and to bring those patients to high functional level and optimal quality of life. In some cases, paradoxically the successful general rehabilitation program can be a strong facilitator of psychiatric rehabilitation process. Our relevant staff, including PRM doctor, psychologists and psychiatrist will share this especial experience with workshop participants, using combination of frontal lectures and practical masterclasses.

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Results expected: Patients with SMI have a good rehabilitation potential in general program and do not differ significantly from no-SMI patients, so it is extremely important to learn the special rehabilitation technique for this population. We expect, that the workshop can help a lot to rehabilitation professionals and ruin the stigma regarding those patients. 14:00 - 15:00 BREAK

Tisa 8:00 - 9:30 WORKSHOP 19 W19. Electrodiagnostics in localization of neural injury at the upper and lower extremities Coordinator: Mark Lissens (Belgium), Marija Hrkovic (Serbia) W19 - 1. Mark Lissens (Belgium): Electrodiagnostic assessment of entrapment neuropathies W19 - 2. Marija Hrkovic (Serbia): Electrodiagnostic assessment of brachial plexopathies Cost: 20 € 9:30 - 10:30 SPONSORED WORKSHOP 20 W20. Spinal muscular atrophy: new therapies and new challenges Coordinator: Evrim Karadag-Saygi (Turkey) W20- 1. Esra Giray (Turkey): Pathophysiology and clinical presentation of Spinal Muscular Atrophy W20- 2. Ozge Kenis-Coskun (Turkey): Nusinersen: how it works, dosing schedule, safety profile W20- 3. Evrim Karadag-Saygi (Turkey): Why should we know Nusinersen treatment as a physiatrist? Real-world clinical setting experience Spinal muscular atrophy (SMA) is one of the most common genetic causes of infantile death. Mutations in the SMN gene result the subsequent loss of motor neurons. Most important symptoms are worsening physical disability, mobility loss and respiratory dysfunction. So, people with SMA will ultimately become totally dependent on their families and caregivers. There are 5 main types (type 0 to 4), based on the age of onset and the maximum motor function achieved, which correlates with prognosis. Almost 60% of patients are type 1 and around 40% are types 2 and 3; types 0 and 4 are rarely diagnosed. Until 2016, there was no disease-modifying treatment and Spinraza (Nusinersen) became the first therapy ever approved by the FDA for SMA patients. It is a synthetic antisense oligonucleotide which works by enabling the SMN2 gene to produce a full length SMN protein.Spinraza shows improvements in both motor function and survival in SMA Types 1, 2 and 3. Physiatrists who plan exercise programs and prescribe assistive devises according to the rehabilitation need of SMA patients should be aware of these new treatment methods.

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Cost: 10 € 10:30 - 11:30 WORKSHOP 21 W21. Long term side effects of cancer and cancer treatments Coordinator: Evren Atabas (Germany) W21-1. Evren Atabas (Germany)

The survival of cancer patients has dramatically improved in the last years due to better early diagnosis and more effective combined treatments. At the same time the impact of cancer and cancer treatments on individual health and social life of affected people is growing up. Although new health issues are emerging, fatigue, muscle weakness, bone loss and chronic pain remain very feared complications in cancer patients and they can cause long-lasting physical, psychological, social and financial problems together with an unsatisfactory quality of life in cancer survivors. It is widely accepted that the etiology of these issues is multifactorial and different risk factors play a role according to the individual and environmental patient's context. Patient evaluation before and after treatment is a strategical step to identify patients at higher risk, adopt primary prevention strategies, and promote early detection and early treatment onset. The workshop presents the most serious complications of cancer therapy and discusses their treatment options from the PRM point of view. Cost: 20 € 11:30 - 15:00 BREAK