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Meiosis and Sexual Life Cycles. Fred and George Weasley … Identical Twins. Heredity. Heredity : the transmission of traits from one generation to the next Asexual reproduction : clones Sexual reproduction : variation. A budding hydra. Karyotyping. - PowerPoint PPT Presentation
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Meiosis and Sexual Life Cycles
Fred and George Weasley… Identical Twins
Heredity
Heredity: the transmission of traits from one generation to the next
Asexual reproduction: clones
Sexual reproduction: variation
A budding hydra
Karyotyping Chromosomes are
photographed, paired, and arranged into a karyotype
Homologous chromosomes- same length, centromere position, and staining pattern– Carry same types of genes
Arranged from longest to shortest– 1-22 = autosomes– #23 = sex chromosomes (X
and Y)
Human Life Cycle 23 pairs of homologous
chromosomes (46) 1 pair of sex and 22 pairs of
autosomes Gametes are haploid (1N); all
other cells are diploid (2N) Fertilization results in a
zygote Meiosis: cell division to
produce haploid gametes
Alternate Life Cycles
Plants and Some Algae
Alternation of generations:
2N sporophyte produces 1N spores by meiosis
Spore can divide by mitosis to create a 1N gametophyte
Gametophyte makes gametes by mitosis which fertilize to become a 2N sporophyte
Most fungi and some protists Meiosis produces 1N
cells that divide by mitosis to produce 1N adults
Adults undergo mitosis to produce gametes
Fertilized gametes become a 2N zygote
Meiosis
After chromosome replication
2 cell divisions (Meiosis I & Meiosis II)
Produces 4 daughter cells – 1/2 chromosome number
(1N)– Variation in gametes that
are produced
Meiosis I Interphase
– Chromosomes and centrosomes replicate
Prophase I – Chromosomes condense– Homologous chromosomes pair
up and crossing over occurs– Synaptonemal complex (protein)
forms between homologues, forming a tetrad
– Centrosomes move to opposite ends of the cell
– Spindle fibers attach to kinetochores and begin moving tetrads to the metaphase plate
Metaphase I– Tetrads line up along the
metaphase plate– Both sister chromatids of a
chromosome are controlled by a single kinetochore
Anaphase I– Homologous chromosomes
are pulled apart– Sister chromatids remain
intact Telophase I and Cytokinesis
– Haploid set of chromosomes– Clevage furrow/Cell plate
forms– In some species,
chromosomes uncoil and nuclear envelope forms
Meiosis II
Prophase II– Mitotic spindle
forms again– Spindle fibers
attach to kinetochores and chromosomes begin moving toward the metaphase plate
MetaphaseII– Chromosomes line
up on metaphase plate as in mitosis
Anaphase II– Chromosomes
separate at the centromere
Telophase II and Cytokinesis– Nuclei form– Chromosomes
decondense– Each of the 4
daughtercells are genetically distinct from the parent cell
Meiosis vs. Mitosis Synapsis/tetrad/chiasmata
(prophase I) Homologous vs.
individual chromosomes (metaphase I)
Sister chromatids do not separate (anaphase I)
Meiosis I separates homologous pairs of chromosomes, not sister chromatids of individual chromosomes.
Genetic Variation Independent assortment:
– homologous chromosomes position and orient randomly (metaphase I)
– In humans, about 8 million different combinations
Recombinant chromosomes (from crossing over)– chromatids are no longer
identical– More possibilities for
genetic variation
Crossing Over Synapsis- homologous
chromosomes come together – Synaptonemal complex holds
them together Form a tetrad Arms of homologues
overlap and form a chiasma Arms of homologues
exchange at gene lines May occur multiple times Produces recombinant
chromosomes
No wonder siblings can be so different!
Random fertilization: 1 sperm (1 of 8 million
possible combinations) x 1 ovum (1 of 8 million possibilities) = 64 trillion diploid combinations!
With the variation from crossing over, the number of possibilities is astronomical
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