Meiosis and Sexual Reproduction Review Sheet

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Biological overview of meiosis and reproduction process for an intermediate biology class.

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    Meiosis and Sexual Reproduction Review Sheet

    Sexual reproduction requires the processes of

    Meiosis(cell division that results in the

    production of gametes (sperm and egg cells

    containing 1/2 the number of chromosomes)

    and fertilization(the fusion of egg and

    sperm cells producing a zygote containingthe normal number of chromosomes).

    For humans, most cells in the body

    contain 46 chromosomes. These are

    called somatic cells.

    For somatic cells, these chromosomes

    can be grouped as matching pairs

    (homologous chromosomes).

    Homologous chromosomes contain

    the same sequence of genes.

    One member comes from the mother one

    member comes from the father.

    However, these genes may have slight variations.

    Example: One chromosome may contain the

    gene for blue eye color while the other

    chromosome may have the gene for green eye

    color.

    Somatic cells are called diploidcells (2N); Forhumans 2n=46 chromosomes.

    Gametes are called haploidcells (1N); For

    humans 1n= 23 chromosomes.

    Type of

    Reproduction

    Cell

    processes

    Offspring

    Makeup

    Advantages Disadvantages

    Asexual

    Reproduction

    Mitosis Genetic copy of

    parent

    Speed

    Requires no

    mate

    No Diversity

    Sexual

    Reproduction

    Meiosis &

    Fertilization

    Combination of

    traits from

    parents

    Genetic

    Diversity

    Greater

    adaptability

    Slower

    Need to find

    mate

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    Asexual Reproduction=Binary Fission

    Sexual Reproduction:Meiosis

    Occurs in the sex organs (testes in males; ovaries in females)

    There is oneDNA replication followed by twocell divisions

    Produces 4 haploid (1N) daughter cells from one diploid (2N) parental cell

    Each daughter cell contains only one member of each homologous pair. Produces

    genetic variation by the processes of crossing overand random assortment of

    chromosomes(see details below)

    Details of MeisosisStep 1: DNA duplicates in S cycle

    Step 2: Meiosis 1: Homologous chromosomes separate

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    Prophase I:

    Duplicated homologous chromosomes condense forminga tetrad

    Crossing over occurs: portions of homologous

    chromosomes exchange DNA

    Nucleus disappears and spindle fibers form (as in

    mitosis prophase)

    Metaphase I:

    Tetrads align in middle of the cell: One duplicated

    chromosome from each pair face opposite poles of the

    cell

    Independent assortment of chromosomes:

    o Each pair of duplicated homologous

    chromosomes align independently from each

    other

    Anaphase I:

    One member of each pair of duplicated homologous chromosomes migrate to

    each pole; sister chromatids remain attached to one another at centromere

    Telophase I and Cytokinesis

    Completion of chromosome migration and cytokinesis occurs

    Have two haploid (1N) cells

    Step 3: Meiosis II: Sister chromatids separate; Meiosis II is very similar to mitosis

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    Prophase II:

    Spindle fibers reform and attach to duplicated chromosomes

    Metaphase II:

    Chromosomes align in middle of cell

    Anaphase II:

    Sister chromatids separate and move to opposite poles (like in mitosis)

    Telophase II and Cytokinesis

    Completion of chromosme migration and cell division

    The result is 4 haploid cells (1N)

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    Comparison between Mitosis and Meiosis

    What happens if meiosis goes bad? Nondisjunction

    Chromosomes fail to separate properly (in anaphase I or II)

    Results in too many or too few chromosomes

    Example 1: Trisomy 21: Downs syndrome; 3 chromosomes 21 instead of 2

    Example 2: Abnormalities in sex chromosomes