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MIDWESTERN UNDERWRITING CONFERENCEMINNEAPOLIS, MN
September 21, 2016
Robert Lund MD
A Geographic Consideration!
12/09/2016Title of presentation and name of speaker 2
Conclusion: We Need to Build More Taverns to Lower Prevalence of Obesity in The United States!
12/09/2016Title of presentation and name of speaker 3
Obesity, US Adults, 2010
The more intense the red thehigher the incidence of obesity
Conclusion: We Need to Build More Taverns to Lower Death Rates Due to Heart Disease in the United States
12/09/2016Title of presentation and name of speaker 4
We May Not Consider Common Chores To Be Associated with Risk
12/09/2016Title of presentation and name of speaker 5
Maybe This Is Why Most Accidents Occur in The Home !
12/09/2016Title of presentation and name of speaker 6
How Complete Are Out MVR’s ?
12/09/2016Title of presentation and name of speaker 7
WEARABLE DEVICES
WILL THEY BE READY FOR PRIME TIME IN LIFEINSURANCE UNDERWRITING ANYTIME SOON?
Midwestern Underwriting Conference
September 21, 2016
Robert W. Lund MD
Probable Inventor of The First Wearable Device
12/09/2016Title of presentation and name of speaker 9
Leonardo da Vinci in 15th Century
Romans used it to calculate the approximate distance military troops had to travel on foot
Da Vinci used it to measure distance more accurately in map making
A gear-driving device with a pendulum arm that would swing to and fro with leg motion while walking
Independence Hall, 1787
12/09/2016Title of presentation and name of speaker 10
The Pedometer: A Mechanical Instrument to Evaluate Walking Behavior
12/09/2016 11
Thomas Jefferson supposedly introduced pedometers (“TomishMeters”) to North America
Pedometers really didn’t catch on until the 1930’s when they became popular with long distance walkers (“Hike-o-meters”)
One pendulum swing produces a “count”
Number of counts x stride length = distance walked
https://www.google.com/search?q=mechanical+pedometer&biw=1680&bih=878&tbm=isch&tbo=u&source=univ&sa=X&sqi=2&ved=0ahUKEwjYyLqU6YTLAhVBox4KHWPaDRcQsAQIUw&dpr=1 Accessed 2/19/2016
http://www.explainthatstuff.com/how-pedometers-work.html Accessed 2/19/2016
Wearable Ambulatory Monitors Sense Physical Motion
Pedometer or Actometer(Assesses “quantity” of “counts”)
Does not well assess older adults with slow or shuffling gaits
Mechanical(count motion only if certain threshold is
reached)Quantity or Quantity and intensity of movement
Electric processing of digitalized data
Electronic
12/09/2016 12Title of presentation and name of speaker
Development of Obesity Problem in The United States Led to Efforts to Increase Activity in The Population
12/09/2016Title of presentation and name of speaker 13
http://www.cdc.gov/nchs/data/hestat/overweight/overweight_adult.pdfAccessed April 25, 2011
Adapted from:
0.00
0.10
0.20
0.30
0.40
1960 1970 1980 1990 2000 2010
BMI = 40 and above
BMI = 30 - 39
BMI = 25 = 29
Proportionof US
Population
Year
Trends in overweight, obesity & extreme obesity in the US
THE ACCELEROMETER
Accelerometers used since the late 1930’s to monitor mechanical wear and force exposure
• An airplane catapult• Passenger elevators• Aircraft shock absorbers
Accelerometers record accelerations of…
• Vibrations of steam turbines and underground pipes• Forces of explosions
Accelerometers record …
12/09/2016 15Title of presentation and name of speaker
In ranges up to 100 g and high Hertz levels
Accelerometer
• Static forces • Constant force of pull of gravity (g = 9.81 m/s2)
• Dynamic forces• Movement
Electromechanical device that will measure acceleration forces
• Determine the angle a device is tilted at with respect to earth
Static acceleration due to gravity
• Detect direction and magnitude of acceleration (g-force or change in g-force)
Dynamic acceleration (vector)
12/09/2016 16Title of presentation and name of speaker
Piezoelectric Accelerometer
12/09/2016Title of presentation and name of speaker 17
Accelerative forces move microscopic crystal structures or piezoceramics and an electric current is generated
Best in high frequency ranges they are preferred in high shock applications
https://www.google.com/search?q=piezoelectric+accelerometer&biw=1664&bih=824&tbm=isch&tbo=u&source=univ&sa=X&sqi=2&ved=0ahUKEwj5udm-h57LAhUJVh4KHSi6AOUQsAQIQQ#imgrc=ki8ZOdztfJ4qZM%3AAccessed 2/29/2016
In an accelerometer, the stress on the crystals occurs as a result of the seismic mass imposing a force on the crystal.
Maximum Swing And Sensitivity
12/09/2016Title of presentation and name of speaker 18
Accelerometer masses have a maximum distance that they will move in response to force.
This may be either positive or negative, depending on the direction from which the force is exerted
The “maximum swing” is expressed as the multiples of “g” that produce it (g = 9.81 m/s2)
Sensitive only in the plane of their specific axis
+
Customary “g” ranges for Maximum Swing± 2 g± 4 g± 8 g± 16 g
The lower the maximum swing “g”, the more sensitivethe measurement but the more limited the range of sensing.Band pass filter limits usually 0.1 – 10 g.
Chen, et al, Medicine & Science in Sports & Exercise, 2005;37(11):s490 – s500.
Figure 1.
12/09/2016Title of presentation and name of speaker 19
Capacitive Accelerometers – Also Measures “g” Or Gravitational Force
If an accelerative force moves one of two adjacent microstructures the capacitance between them is changed and this can be expressed as an electric current.
Capacitive accelerometers performance is superior in the low frequency range.
AThe deformation caused by the pressure is measured
using a capacitive element. The pressure P will cause a variation of the distance between the two electrodes
BChange in capacitance due to lateral movement of
plates
A
B
https://www.google.com/search?q=capacitance+accelerometer&biw=1664&bih=824&tbm=isch&tbo=u&source=univ&sa=X&sqi=2&ved=0ahUKEwiZ64Dcg57LAhXDuB4KHbo7C94QsAQIIw#imgrc=BeqPecsovmr-0M%3AAccessed 2/29/2016
Accelerometer As A Single body-Fixed Sensor
12/09/2016Title of presentation and name of speaker 20Weiss A, et al, Neurorehabilitation and Neural Repair 2013;27(8):742 – 752.
Figure 1.
Used by kinesiologists, sport physiologists, etc.
Electronic Wearable Ambulatory Monitor (WAM)
• can be attached to the body or embedded in a clothing garment
Wearable electronic sensor
• Earliest WAM’s had a single uniaxial accelerometer
Accelerometers record the user’s bodily movements
• Doesn’t account for multidirectional bodily movement• Insensitive to low-intensity activities• Insensitive to changes in grade while walking or running
Uniaxial accelerometry (Caltrac®) tends to underestimate bodily energy expenditure
12/09/2016 21Title of presentation and name of speaker
Development of A Triaxial AccelerometerBouten CV, et al, 1997 Paper
Three orthogonally mounted uniaxial piezoresistive accelerometers
Assessed physical movement via human body accelerations
Respond to both the frequency and intensity of human movement
Demonstrated a significant relationship between energy expenditure as estimated by accelerometry and energy expenditure as determined by indirect calorimetry (r = 0.89)
Shortcomings:
Low sensitivity to sedentary activities
Inabililty to register static exercise
12/09/2016 22Title of presentation and name of speaker
Bouten CV, et al, IEEE Transactions on Biomedical Engineering 1997;44(3):136 – 147.
9/12/2016 23
Micro-electro-mechanical System (MEMS) Technology
SMART PHONES AND MINIATURIZATION
Evolving Cell (Smart) Phone Technology
12/09/2016Title of presentation and name of speaker 25
Enhanced computer capacity
Miniaturization
Internet connectivity
GPS
Miniaturizationiphone 4’s Mother Board
12/09/2016 26
12/09/2016Title of presentation and name of speaker 27
Micro-electro-mechanical System (MEMS) Technology& Smartphones
Advent of micro-electro-mechanical system (MEMS) technology enabled accelerometers and other sensing components to be miniaturized leading to smaller wearable sensors
Development and generalized use of “smartphones” having comparatively advanced computing capabilities, GPS receivers and MEMS sensors make them an ideal platform from which to monitor human movement
Main board, iPhone 4
Gyroscope
Accelerometer
Moore’s Law May Soon Become Outmoded
• “The number of components that could be etched onto the surface of a silicon wafer was doubling at regular intervals and would do so for the foreseeable future”
Gordon Moore (co-founder of Intel) in 1965:
• Chips may soon be made out of other materials (e.g. graphene)
We’ve reached the limit on making silicon chips smaller
12/09/2016 28Title of presentation and name of speaker
The New York Times http://nyti.ms/1q0qd24.Accessed 5/10/2016
Development of Consumer-Based Physical Activity Monitors (“Wearables”)
Personalized social media “apps”
• Low-cost, miniaturized accelerometers• Bluetooth technology
Refinement of technology
• Web sites• Cell phone applications
Physical activity and energy expenditure data tracking
12/09/2016 29Title of presentation and name of speaker
Wearable Devices: “Wearables”(Smart phones, smart watches, wrist bands)
• Fitbit• Nike +
First wearable fitness devices appeared in 2009
• Two leading platforms• iOS• Android
Over 100,000 health focused “apps” released by Q1 2014
• Quantified-self movement• Distance walked• Calories burned• Heart rate
Development of “wearables” mainly consumer driven
12/09/2016 30Title of presentation and name of speaker
Smartphone Multimodal Sensors to Identify Physical Movement
• Location (GPS)• Audio-visual components
Contextual sensors
• Ambient light• Barometric pressure• Magnetometer
Environmental change sensors
• Accelerometer• Gyroscope
Body movement
12/09/2016 31Title of presentation and name of speaker
Evolution of Smartphone Algorithms Enabling Greater Variety in Body Positioning
del Rosario MB, et al, Sensors, 2015;15:18901 – 18933.
Figure 4.
Motion MEMS Sensors in Smartphones
• Measures combined acceleration due to gravity and bodily movement along three orthogonal axes
• Determines “roll,” “pitch” and “yaw”
Triaxial accelerometer
• Measure angular velocity along three orthogonal axes• Changes in orientation of the device determined
Triaxial gyroscope (plus the accererlmeter)
• Uses environmental magnetic sources to determine a heading relative to the magnetic north pole
• Combined with accelerometer readings enables determination of “yaw”
Triaxial magnetometer
• Determines changes in altitude
Barometric pressure sensor
12/09/2016 33Title of presentation and name of speaker
Climbing Stairs with Smartphone in Back Pocket
12/09/2016Title of presentation and name of speaker 34del Rosario MB, et al, Sensors, 2015;15:18901 – 18933.
Figure 2.
PROCESSING THE DATA
Bandwidth – Sampling Rate (should have a frequency at least twice that of the highest frequency movement)
• Nonimpact PA: < 8 Hz (e.g., running)• Upper limit: As high as 25 Hz (specific movements of arms)
Frequency of physical activity (PA) in humans
• 1 to 64 Hz
Sampling frequency of commercially available PA monitors
• Preset low and high frequency limit (usually ~ 0.25 – 7 Hz)• Narrow bandwidth: incomplete data collection• Too broad bandwidth: corrupting electrical artifact and “noise”
Sensor output is filtered
12/09/2016 36Title of presentation and name of speaker
How Raw Accelerometer Data Is Processed inActigraph GT3X
• 0.05 – 2.5 g Accelerations• Sampling rate of 30 Hertz (Hz)
Detecting bodily motion
• Digitized by A/D converter• Digital filter that band limits accelerometer frequency range
• 0.25 to 2.5 Hz (frequency of most bodily movement)
Acceleration signal
• Epoch
Digitized signal summed over time
12/09/2016 37Title of presentation and name of speaker
Obtaining EE from raw vector magnitude activity countsDetermining the counts (aggregated values indicating frequency and intensity of movement)
12/09/2016Title of presentation and name of speaker 38
Objects on Earth are subject to gravitational acceleration. Data from each axis (X, Yand Z) is filtered by a mathematical formula to isolate gravitational acceleration and to remove the force of gravity to obtain linear acceleration for each axis
Linear acceleration values may be either negative or positive so they are “normalized”to obtain all positive values
Linear X2 + Linear Y2 + Linear Z2
Chen, et al, Medicine & Science in Sports & Exercise, 2005;37(11):s490 – s500.
Figure 2.
Obtaining EE from raw vector magnitude activity countsDetermining the counts
12/09/2016Title of presentation and name of speaker 39
Calculate the area under the curve using an integration process. Thisproduces the total number of counts obtained by the accelerometerfor the physical activity performed over that period of time. Time elapsedIs often divided up into “epochs.” Here the epochs are of 15 sec. duration
Chen, et al, Medicine & Science in Sports & Exercise, 2005;37(11):s490 – s500.Figure 2.
DETERMINING ENERGY EXPENDITURE (EE)
How Accurate Are The Numbers ?
12/09/2016Title of presentation and name of speaker 41
ATP, The Body’s Energy Packet, Is Formed through The Oxidation of Carbon Atoms
12/09/2016Title of presentation and name of speaker 42
http://www.medbio.info/Horn/Body%20Energy/body_energy.htmAccessed 3/23/2015
VO2max—the amount of oxygen the body is able to use
Carbon atoms from ingestion ofsugars, starch, fat and proteins
Oxidation
ATP production requires food and adequate circulation, lung function and physical condition
Oxygen from respiration
12/09/2016Title of presentation and name of speaker 43
Indirect calorimetry measures 02 consumption and CO2 production prospectively and with precision from which the rate of EE can be calculated (kcal / min)
Good way to calculate energy expenditure over limited periods of time whileperforming specific physical activities (Kcal / minute)
3.5 ml O2 / Kg / min = 1 MET (metabolic equivalent)
Doubly Labeled Water Method of Determining Energy Expenditure by Indirect Calorimetry
12/09/2016Title of presentation and name of speaker 44
(2H) leaves the body as water, while 18O leaves as water (H2O) and carbon dioxide (CO2). Therefore, CO2 production can be calculated by subtracting 2H elimination from 18O elimination and the total metabolic rate may be estimated.
Good for determining EE in free living situations over time (usually 7 to 14 days)
Results: Kcal / day
Correlating Energy Expenditure with Accelerometer Output Data (Vector Activity Counts or Vector Magnitude Activity Counts
12/09/2016Title of presentation and name of speaker 45
12/09/2016Title of presentation and name of speaker 46
Calibration of the Computer Science and Applications, Inc. Accelerometer (now “Actigraph”)
Relationship between treadmill speed and oxygen consumption
Relationship between treadmill speed and activity counts
Freedson PS, et al, Medicine & Science in Sports & Exercise, 1998;30(5):777 – 781.
Figure 1. Figure 2.
• 3.5 ml O2 / Kg / Min
1 MET =
• 1.439008 + (0.000795 x counts / minute)
METS =
• r = .88
Correlation coefficient =
12/09/2016 47
Determining Number of METS from Single Vector Activity Counts
Single vector activity counts versus METS
Figure 3.Freedson PS, et al, Medicine & Science in Sports & Exercise, 1998;30(5):777 – 781.
Walk Run Transition
EntrantEnergy
ExpenditureMeasured
(x)Estimated
(y) (x*y) (x2) (y2)
1 .0482 .0564 .00272 .00232 .00318
2 .0438 .0544 .00238 .00192 .00296
3 .0461 .0555 .00256 .00213 .00308
4 .0472 .0559 .00264 .00223 .00312
12/09/2016Title of presentation and name of speaker 48
Correlation Coefficient Formula – Finding “ r “
Correlating EE, Measured versus Estimated(Kcal / kg / min) “ r ” = Correlation Coefficient
http://study.com/academy/lesson/pearson-correlation-coefficient-formula-example-significance.htmlAccessed 3/7/2016
r values concerning quantitative scientificdata: > 0.8 generally indicate “strong” correlation.
Non-quantitative data demonstrating r values~ 0.5 considered “acceptable”
• 0.0000191 x vector activity counts x mass in Kg
Manufacturer provided equation: 1 Kcal / min =
• (0.00094 x counts / min) + (0.1346 x mass in Kg) - 7.37418
1 Kcal / min =
• r = .93
Correlation coefficient =
12/09/2016 49
Determining Predicted Energy Expenditure from Single Vector Activity Counts And Body Mass (kg)
Predicted versus actual energy expenditure (Kcal / min)
Calculating equations often are proprietary and are determined at factory calibration
Figure 4.
Freedson PS, et al, Medicine & Science in Sports & Exercise, 1998;30(5):777 – 781.
King GA, et al, Med. Sci. Sports exerc., 2004;36(7):1244 – 1251.
Computer Science Application, Inc. (CSA, now “Actigraph”) Accelerometer Correlates Relatively Well with Indirect Calorimetry at Usual Walking Speeds
12/09/2016 50
Correlation between CSA total EE estimated by Freedson equation and indirect calorimetry is relatively good at usual walking speeds
r = .73 at 2 mph
Correlation decreases as treadmill speed increases
r = .58 at 8 mph
King GA, et al, Med. Sci. Sports Exerc., 2004;36(7):1244 – 1251.
Being Able to Adjust Accelerometer Sensitivity Level Does Not Insure Good Correlation
12/09/2016Title of presentation and name of speaker 51
BioTrainer-Pro
Biaxial accelerometer
User-specified sensitivity level of measurement
X1, x2, x4, x10, x20 and x 40 G
Sensitivity was set at 4 G
Correlation coefficients
r = .34 at 2 mph
r = .485 at 8 mph
King GA, et al, Med. Sci. Sports Exerc., 2004;36(7):1244 – 1251.
BioTrainer-Pro
IndirectCalorimetry
Both the “g” and the “Hz” Settings Are Crucial toObtaining Good Data
12/09/2016Title of presentation and name of speaker 52
Adapted from Table 1.
Ruiz-Zafra A, et al, Sensors, 2015;15:18270 – 18286.
Unfiltered Hz Is Too High in Zephyr (50 Hz)
12/09/2016Title of presentation and name of speaker 53
METS
Ruiz-Zafra A, et al, Sensors, 2015;15:18270 – 18286.
Figure 6.
Static Activities Not Tightly Associated with Bodily Acceleration
12/09/2016 54
Activities with muscle contractionthat expend energy but are not associated with much physicalmotion
All monitors underestimate energy cost by ~ 50%
METS
Matthews CE, Med. Sci. Sports Exerc., 2005;37(11):S512 – S522. Adapted from Figure 3.
• METS = 2.8323 + 0.00054 x vector magnitude activity counts/min. – 0.059123 x body mass (kg) + 1.4410 x gender(women = 1, men = 2)
Adults
• METS = 2.5878 + 0.00047 x vector magnitude activity counts/min. – 0.06453 x gender (women = 1, men = 2)
Elderly
12/09/2016 55
Proper Calibration of Physical Activity EE Is Most Accurately Done When Biometric Data (Age, Gender, Weight) Are Considered
Actigraph Calibration Study (not using biometric data – age, gender, build)
Actigraph GT3X Correlation Formulas
Figure 4.
Matthews Charles E., Medicine & Science in Sports & Exercise 2005;0195-9131/05/3711:S512 – S522.
Santos-Lozano A, et al, Int J Sports Med 2013;34:975 – 982.
Resting Energy Expenditure (kcal / min)
• (0.00473 x wt (kg)) + (0.00971 x ht (cm)) –(0.00513 x age (yr)) + 0.04687
Men
• (0.00331 x wt (kg)) + (0.00352 x ht (cm)) –(0.00353 x age (yr)) + 0.49854
Women
12/09/2016 56Title of presentation and name of speaker
Nichols JF, et al, Medicine & Science in Sports & Exercise 1999;31(6):908 – 912.
Converting METS to Kcal
Physical Activity EE
• Kcal = METS x wt (kg) x time (hours)
Total EE
• Total EE = Activity EE + Resting EE
12/09/2016 57Title of presentation and name of speaker
We Are Homeothermic, Attempting to Maintain A Constant Body Temperature – A Direct Calorimetry Method
12/09/2016Title of presentation and name of speaker 58
http://www.lifechek.com/technology2.htmlAccessed 2/23/2016
Heat flow sensor measurements in context of an individual’s body surface area, are used to calculate calorie expenditure
Heat loss: conductive, radiant, convective and evaporative
Mostly: radiant and convectiveWith exercise: evaporative
SenseWear Armband Overestimated Energy Expenditure at All Treadmill Speeds
12/09/2016 59
SenseWear Armband: biaxial accelerometer, heart rate receiver and thermocouple (measures heat production, e.g. direct calorimetry)
Correlation coefficients were not so good at walking speeds (r = .65 at 2 mph)
Correlation coefficients were good at faster treadmill speeds ( r = .82 at 8 mph)
King GA, et al, Med. Sci. Sports Exerc., 2004;36(7):1244 – 1251.
Some Commercial Examples
Table 6.
Del Rosario MB, et al, Sensors 2015;15:18901 – 18933.
In Der Spiegel May 4, 2016
12/09/2016Title of presentation and name of speaker 61
Comparing Estimated (by Wearable Device) and Actual (by both Metabolic Chamber and Doubly Labeled Water Method) TEE
12/09/2016Title of presentation and name of speaker 62
Murakami H, et al, jamainternalmedicine.com 2016:E1 – E2.
“r” “r”
Estimate the activity limit which would cause the applicant to become uncomfortable or want to stop
12/09/2016Title of presentation and name of speaker 63
1 Eating, standing, getting dressed, playing cards
2 Showering, ironing, cooking, washing dishes, walking down 8 steps
3 Making the bed, grocery shopping, sweeping or vacuuming floors
4 Raking leaves, weeding, mowing lawn (power mower), painting
5 Playing doubles tennis, social dancing, washing the car
6 Mowing lawn (push mower), playing 9 holes of golf carrying own clubs,carpentry
7 Digging or spading of soil, walking uphill, carrying 60 pounds (27 Kg) on level surface
8 Carrying groceries upstairs or climbing a flight of stairs quickly, moving heavy furniture> 9 No limitations from any of above
METS
Physical Activity Questionnaires (PAQ) Demonstrate Poor Reliability in Estimating Activity Energy Expenditure (AEE)
• Average “r” = .42 for series of 14 studies
Low to Moderate Correlation Coefficients
• Inaccurate recall• PAQ did not include key activities relating to AEE
Discrepancies due to …
• Older individuals• When individuals are considered rather than groups
Discrepancies Especially with …
12/09/2016 64Title of presentation and name of speaker
Bonnefoy M, et al, J Am Geriatr Soc 2001;49:28 – 35.Neilson HK, et al, Am J Clin Nutr 2008;87:279 – 91.
HOW DOES TOTAL ENERGY EXPENDITURE CORRELATE WITH MORTALITY RISK ASSESSMENT ?
12/09/2016Title of presentation and name of speaker 66
Both Exercise Capacity And Activity Pattern Better Predictor of Overall Mortality Relative to Usual Risk Factors
59 y.o. men referred for TMT for clinical reasons. Given physical activity questionnaire (Paffenbarger),
“r” = 0.39, from which energy costs were estimated
Survival predictors were exercise capacity followed by energy expenditure from recreational activity. 1000 kcal/wkincrease in PA = 1 MET improvement in fitness and 20% better survival
MR = 172 %
MR = 79 %
MR = 187 %
MR = 60 %
Figure 1. Figure 1.
Myers J, et al, Am J Med 2004;117:912 – 918.Paffenbarger RS, et al, NEJM 1986;314:605 – 613.
WHAT OUTPUTS FROM WEARABLE DEVICES OTHER THAN KCAL MIGHT BE USEFUL?
Males Older Than 70 Years Tested for Gait Speed And Followed for 5 Years for Mortality
• Gait speed < 0.82 m/s (2.69 f/s)
Mortality Began to Rise
• Gait speed > 1.36 m/s (4.46 f/s)
No Deaths Observed
12/09/2016 68Title of presentation and name of speaker
Stanaway FF, et al, How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over, BMJ 2011;343:d7679.
Studenski S, Gait Speed and Survival in Older Adults, JAMA 2011;305(1):50 – 58.
12/09/2016Title of presentation and name of speaker 69
~ 34,500 participants, over 17,500 deaths, Metaanalysis
Gait Speed Is A Good Indicator of Mortality in The Elderly (and easily determined)
• ~ 0.80 M/sec Studenski S, et al, JAMA 2011;305(1):50 – 58.
Mortality begins to Rise for Males in Early 70’s
• Gait Speed < 0.8 M/sec British Geriatrics Society, Dec 2014
Frailty Indicators
12/09/2016 70Title of presentation and name of speaker
Barometric Pressure Sensor in A Smartphone
Climbing one flight of stairs ~ 5 METS Climbing one flight of stairs ~ at least New York Heart Functional Class 2
Figure 1.Figure 2.
Regulation of Physical Activity Apps Not Yet Done
• FDA decided not to regulate so – called “low risk” health apps
• FDA is currently focused on the small subset of mobile medical apps that may be associated with potential patient risk
As of First Quarter 2015
12/09/2016 72Title of presentation and name of speaker
Ideal Physical Activity Monitor for Insurance Applicants
Capacitive Accelerometer (better for detecting more sedentary movement)
• Sampling Rate ~ 30 Hz (could be up to 50 Hz)• Band width filter: 0.25 – 7.0 Hz• Sensitivity to g forces: 0.3 – 4 g• Length of EPOCH’s for averaging must be optimized
Correlation formulas (must be transparent and done on representative participant populations)
• Determined using doubly labeled water• Free living activity over several days
• Consider biometric data (age, gender, weight)• Separate equations developed for adults and for the elderly
12/09/2016 73Title of presentation and name of speaker
POTENTIAL FOR FRAUD !
IS THE DATA ACTUALLY DERIVED FROM THE APPLICANT ?
Fitbit for You, FitBark for Fido
12/09/2016Title of presentation and name of speaker 75
Activity trainer for dogs
For health enthusiasts who own dogs orFor dogs with certain medical conditions
http://www.dallasnews.com/lifestyles/health-and-fitness/health/20160404-fitbit-for-you-fitbark-for-fido-will-this-make-your-pet-healthier.ece Accessed 4/5/2016
Also Monitoring Against Fraud
12/09/2016Title of presentation and name of speaker 76
Had Enough?
Industry underwriter away from desk for more than 60 minutes
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