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MiyagiIdeal Environment for Business & Research

International Business Promotion Division

Miyagi Prefectural Government

General Information

GDP 9.5 Trillion yen 14th in Japan, 1st in the Tohoku Region

(34 trillion yen for the entire Tohoku region)

+10％ growth in GDPFrom 2006 to 2016; 2nd highest in Japan

2.3 million people 14th in Japan, 1st in the Tohoku Region

+400 company establishments From 2006 to 2018

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Over 100 Institutions of Higher EducationNumber of university students：57,396Number of exchange students：4,632

10 domestic flights to 10 cities5 international flights to 6 citiesTo become a 24-hour operating airport3,000-meter runway makes possible to fly to London with non stop

Trade potential with over 100 countriesThe only International trading harbor in Tohoku

Population of foreign nationals：21,614Capital City：Ranked 2rd for comfortable living in Japan

Around 30 industrial parks80％ accessible in 10 min from highways

Office rent cost：1/2 of TokyoIndustrial Land Cost ：1/16 of Tokyo

A Region with High Potential

Miyagi’s capital city designated as a “Startup Ecosystem Promotion City” (8 locations in Japan)

Foreigners who wish to open a startup company in Miyagi’s capital can receive special visa status in the initial stage

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Tohoku University

Miyagi’s Advantage: R&D Environment

Ranked 1st in Japan Japan University Rankings 2021, Times Higher Education (UK)

Ranked 2nd in Japan for Joint Research Funds with International CorporationsIndustry-university Collaborative Research in University and Other Institutions, Ministry of Education, Culture, Sports, Science and Technology, 2018

Designated National University (2017)

In collaboration with 250 the world leading institutions in 35countries and regions

© Tohoku Univ ersity

Industry-Academia Collaboration Environment at Tohoku University

• 137 fields of study seeds at life science

• Japan’s first next-generation synchrotron radiation facility under construction which will be operational in2023

• Japan’s first JETRO Innovation Desk established inside Tohoku University to promote active collaboration between researchers and companies © Photon Science Innovation Center

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Tohoku University: Life Science and Medicine

• Central hospital for clinical research with

data on 800,000 patients

• One of Japan’s largest university hospitals• Applying medical care for the next

generation• Satellite laboratories of the Graduate

Schools of Pharmaceutical Sciences,

Biomedical Engineering & Engineering• Attracting R&D from various industries

• World’s first comprehensive three-generation

cohort study (70,000 participants)

• Japan’s largest cohort study (150,000 participants)• Leading composite biobank

• Developing medical care for the next generation

Motto: “Under One Roof”

Cooperative Research Base

Graduate School

of DentistryInstitute of Development,

Aging and Cancer

School of Medicine

• One of the largest centers for translational research

• Only center promoting open innovation of medical

equipment development• Promoting industry-academia cooperation for R&D in

various fields• Promoting clinical immersion

• Implementation of medical care for the next generation

United Centers for Advanced Research

& Translational Medicine

Japan’s only national university-

affiliated aging research center

Smart Aging International Research Center

Tohoku University Hospital

Clinical Research, Innovation &

Education Center (CRIETO)

Tohoku Medical Megabank

Organization

Life Science R&D Environment at Tohoku University

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Example of a Foreign-affiliated Company in Miyagi

■ Philips Co-Creation Center, opened on May 28, 2019

※Company’s first innovation center in Japan

Philips Japan

➢ As Tohoku Region has the one of the fastest aging population in all of Japan, Miyagi was the ideal location for Philips Japan to be exposed early on to the currentchallenges and to carry out innovative R&D and testing and to develop itstechnology for other regions of the country.

■Concluded comprehensive partnership agreement with Tohoku University

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Institution Research Summary Collaboration Opportunities

Tohoku Medical MegabankOrganization (ToMMo)

⚫ World’s largest comprehensive biobank⚫ World’s first three-generation cohort study

(more than 70,000 participants)

⚫ Development of personalized medicine using extensive genetic information

Tohoku University Smart-Aging Research Center & Institute of Development Aging and Cancer (IDAC)

⚫ Japan’s only institute specializing in aging medicine research

⚫ Development of anti-aging technology

Tohoku University Hospital OPEN BED Lab

⚫ Japan’s first open bed lab, turning old hospital beds into a field for companies to carry out R&D verification

⚫ Joint R&D can also be implemented at the OPEN BED Lab, incorporating views of

⚫ Possible to verify and test medical devices and prototypes at the conceptual stage for nursing care and health fields

Tohoku University Graduate School of BiomedicalEngineering

⚫ Japan’s first institution for the development of basic medical device technology through the integration of biomedicine and engineering

⚫ Development of new medical devices through the integration of biomedicine and engineering

Tohoku University Hospital AI Lab

⚫ Providing support for AI development aimed to resolve everyday issues in the medical field by intervening on the problem setting and design process

⚫ Supporting AI development to resolve everyday issues in the medical field

Academic Science Unit ⚫ Companies can directly access the medical field to observe and search for the needs of the field

⚫ Program to use design thinking to narrow down needs found on site and to discover solutions to the issues

⚫ Seeking companies that aim to commercialize medical devices, systems and services based on the needs of the medical field

Business Opportunities in Miyagi

Tohoku University-affiliated Institutions

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Researchers Research Summary Collaboration Opportunities

Professor A ⚫ Using AI analysis of brain MRI data to

evaluate the impact lifestyle and other factors on the brain’s health

⚫ Consulting service for neurodevelopment and mental health; possible to evaluate dementia prevention by brain imaging analysis

⚫ Research on brain development and

aging using brain MRI database⚫ Seeking to collaborate with

companies developing lifestyle products

Professor B ⚫ Application of mathematical modeling and

machine learning to analyze medical imagine⚫ Application of forensic imaging to investigate

cause of death (mammography analysis, AI)

⚫ Joint research with medical device

companies

Professor C ⚫ Development of blood vessel and bone

models with realistic physical features and mechanical properties

⚫ Medical device optimal design research using optimization methods advances the development of stents and catheters

necessary for cerebral aneurysm treatment

⚫ Possible to collaborate with medical

device companies⚫ Technology is expected to be

applied in various fields including medical imaging equipment, application development using

MEMS and medical training

Assistant Professor D ⚫ Development of AI software for Intensity

Modulated Radiation Therapy (IMRT)⚫ Solving issues by applying AI technology to

design and verify appropriate treatment plans for IMRT

⚫ Seeking to collaborate with

companies developing radiation treatment planning devices and

radiation treatment devices

Professor E ⚫ Simple and inexpensive PCR testing

technology for fields including research,health management, food testing and

medical diagnosis

⚫ Seeking to collaborate mainly with

companies developing medical diagnostic and testing kits in

developing countries

Business Opportunities in Miyagi

Tohoku University Researchers

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Company Name Characteristics/Services Areas for Possible Collaboration

Company A ⚫ Development of rare metal-free high-quality electrode catalyst first discovered as a result of research conducted at the Advanced Institute for Materials Research, Tohoku University

⚫ Applying technology in metal air batteries (hearing aids, wearable medical devices, healthcare IoT)

Company B ⚫ ・Currently developing a sensor that can measure the concentration of organic compounds at the 1PPM level

⚫ Development of sensors for virus detection, etc.

Company C ⚫ Development of a next-generation human model that is very close to a real human being (not only organs and blood vessels but a model that can also sense feelings)

⚫ Treatment simulation and training⚫ Providing a test platform for products that

pursue precision in medical device development

Company D ⚫ Development of a new conductive fiber using natural silk with conductivity in the fiber itself

⚫ Vital sensing that reduces risks including discomfort and measurement failure due to inflammation or heat

Company E ⚫ Developed the world’s first concept of a machine learningalgorithm that achieves a “reference system” and that can learn from human intentions and correlation

⚫ Possible to evaluate in actual time, and to carry out high-precision feature extraction from noisy time series data (biological data etc.)

Company F ⚫ Providing genetic testing simultaneously without special equipment or training

⚫ Simple genetic testing service

Company G ⚫ Developed world’s first supercritical synthesis and organicsynthesis technology

⚫ Development of hybrid materials using supercritical water (developing products that can be applied to various medical needs)

Company H ⚫ Institute of Development Aging and Cancer, Tohoku University spin-out company

⚫ R&D related to brain function, dementia risk early detection, research on dementia prevention

⚫ Data science business based on neuroscience and medical evidence

Company I ⚫ Developing an endoscopic anchor tool for acute cholecystitis while using the knowledge of Tohoku University’s School of Engineering

⚫ Development of a groundbreaking treatment for acute cholecystitis that is safe with minimal pain

Business Opportunities in MiyagiExamples of Startup Companies in Miyagi

Achievements Miyagi ranks 3 in Japan for most number of university spin-out companies8

Company Name Characteristics/Services Areas for Possible Collaboration

Company J ⚫ Offering ultra-precision polishing with surface roughness Ra1 nm, using the company’s world-class polishing technology

⚫ Customers include more than 4,000 domestic and overseas companies in the medical device field, etc.

⚫ Processing, designing and producing various parts for medical devices using company’s ultra-precision polishing/lapping technology

Company K ⚫ Development of chemiluminescence analyzer, the world’s most sensitive photon counting device

⚫ Detection of bacteria, virus (can detect to the level of 1 yeast particle)

⚫ Evaluation of early stage of oxidation of medical materials, etc.

Company L ⚫ Precision molding parts, precision machinery parts, jig and tool design, etc.

⚫ Specializing in difficult to cut material processing⚫ Possible to carry out service from design, processing to

evaluation

⚫ Processing and manufacturing jig and tools, equipment parts (related to medical devices)

Company M ⚫ Japan’s first one-stop service company for the metal 3D printing field from metal powder material development, production, and prototyping to mass production

⚫ Modeling of all types of metal possible with the technical support from the Institute for Materials Research, Tohoku University

⚫ Printing medical implants, medical device parts, etc.

Company N ⚫ Leading company in vacuum coating technology⚫ Advanced coating technology can be applied to any fields

⚫ Applying coating technology in the development of medical equipment and devices

Company O ⚫ Manufacturing special alloys, alloys and new technology⚫ Technical support from the Institute for Materials Research,

Tohoku University

⚫ Development of medical device parts, artificial joint materials, etc.

Business Opportunities in Miyagi

Achievements Miyagi ranks 4th in Japan for shipment value of electronic parts, devices and electronic circuit manufacturing products

Examples of Local Companies in Miyagi

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1. Tohoku University – Home to a unique R&D and industry-academia collaboration environment found no where else in Japan

➢ Only location in Japan where companies can conduct R&D verification directly on-site in the medical field

➢ Creating innovative AI solutions for medical issues

➢ Japan’s only aging research institution to respond to the rapid aging society

➢ Developed the world’s largest comprehensive biobank; world’s first three-generation cohort study conducted

here with participation from 70,000 people

２. Concentration of high-tech companies in Miyagi

➢ Numerous start-up companies using Tohoku University’s world-class research sources (ranking 3 rd in Japan

for number of start-up companies)

➢ Local companies also utilize the innovative technology developed by the university, etc.

1.Companies developing medical devices and services based on the needs of the medical field

2.Companies interested in providing medical services using AI

3.Companies seeking ultra-precision parts for medical devices, electronic parts production and processing technology

4.Companies interested in personalized medicine, development of anti-aging technology, development of new medical devices through the collaboration with medical engineering

Target industries, sectors, and companies

Region’s Advantages

Miyagi’s Advantages for the RBC Program

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✓ Matching support with universities and research institutionsIndustry-Academia

Collaboration

Introduction to Public Institutions

Business Matching Support

Introduction to Property

✓ Introduction to national government, local municipalities, etc.

Human Resource Recruitment

✓ Introducing and supporting business matching with Miyagi companies

✓ Introducing office, co-working office spaces, and other properties

✓ Introduction to human resource recruitment companies✓ Introduction to university recruitment office✓ Organize exchange meetings with international students

Miyagi welcomes all of youCome discuss with us how we can support your business!

Subsidy Program✓ Subsidy✓ Introduction of subsidy programs✓ Support with subsidy applications, permit procedures, etc.

International Business Promotion Division, Miyagi Prefectural Government 3-8-1 Honcho, Aoba-ku, Sendai City, Miyagi Prefecture 980-8570TEL +81-022-211-2962 E-mail: gb1@pref.miyagi.lg.jp

Copyright(C)2021 Miyagi Prefectural Government. All Rights Reserved.