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Molecular biology (Zoo-342)Molecular biology (Zoo-342)
Dr. Mikhlid Hamed Almutairi
Associate Professor
Medical Molecular genetics
Department of Zoology , College of ScienceKing Saud University P.O. Box 2455, Riyadh 11451 Saudi Arabia
Office number: 67أب , Ground floor
Emails: [email protected]
المطيري: حامد بن مخلد الدكتور
مساعد أستاذ
الطبية الجزيئية الوراثة
الملك جامعة العلوم، كلية الحيوان، علم قسمسعود
رقم البريد الرمز 2455صندوق الرياض، ،11451البريدي
السعودية العربية المملكة
: أب المكتب األرضي 67رقم الدور ، : االلكتروني [email protected]البريد
Aims of the Molecular Biology courseTo study the properties of genetic material.To understand the structure of DNA and its
organization in chromatin.To understand the structure of RNA and its types.To understand the of DNA replication.To understand the key features of gene.To study the gene expression: Transcription in
prokaryotic cells.To study the gene expression: Transcription in
eukaryotic cells.To study the gene expression: Translation in
prokaryotic cells.To study the gene expression: Translation in
eukaryotic cells.
Time table for weekly planning for Molecular Biology
Lectures Dates Syllabus view1 16/4/1436 Required properties of genetic material2 23/4/1436 Structure of DNA and RNA3 30/4/1436 DNA replication4 7/5/1436 The eukaryotic chromosome and chromatin
organization5 14/5/1436 Centromeres and telomeres6 21/5/1436 Changes in chromosome structure and
number7 28/5/1436 Exam 18 2/6/1436 Half term break holidays9 13/6/1436 Gene expression10 20/6/1436 Prokaryotic transcription: The process11 27/6/1436 Eukaryotic transcription12 4/7/1436 Posttranscriptional modification in
eukaryotes13 11/7/1436 Prokaryotic translation 14 18/7/1436 Eukaryotic translation 15 25/7/1436 Exam 2
Assessment
Lecture2 lecture exams (25%)Attendance, participation and homework (5%)Final exam (40%)70% of total grade
Laboratory30% of total grade
Required properties of a genetic material:
1) It must contain information that control the synthesis of protein and function.
2) It must be able to self-replicate.3) It must be located in the chromosomes, which
had been found to carry traits from one generation to the next.Types of genetic materials:
1) DNA: is the genetic material in most organisms, such as humans, animals, plants, viruses, and bacteria.
2) RNA: in some viruses, RNA serves as the genetic material.
1) DNA (deoxyribonuclic acid)
2) RNA (ribonuclic acid)
Types of nucleic acids
The structure of nucleoside and nucleotide
Nucleoside= nitrogen base + sugarNucleotide= nitrogen base + sugar +
phosphte
The structure of the four nucleotides
A polymer of nucleotides
The Watson-Crick model
Hydrogen bonds
Polarity of the DNA strand
