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1 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare Cowen and Company 37 th Annual Health Care Conference Boston Marriott Copley Place, Boston, MA www.cowen.com Conferences Agenda MONDAY, MARCH 6, 2017 Schedule Overview 7:00 AM – 5:45 PM Registration Atrium, 3 rd Floor 7:00 AM – 8:00 AM Breakfast Buffet Salon E, 4 th Floor 8:00 AM – 12:15 PM General Session and Topical Panels Salons F, G, H, 4 th Floor 8:00 AM – 5:55 PM Private Company Presentations MIT, 3 rd Floor 12:20 PM – 1:15 PM Lunch – Health Care Jeopardy! Welcome Remarks – Jeff Solomon President, Cowen Group Salon E, 4 th Floor 1:20 PM – 5:45 PM Public Company Presentations 1 st , 2 nd , 3 rd and 4 th Floors 6:00 PM – 7:00 PM Networking Reception Atrium, 3 rd Floor General Session 8:00 AM – 8:55 AM Cowen Moderator: Chris Krueger ACA Repeal/Replace and the 2017 GOP Healthcare Agenda Crossroads Strategies Mat Lapinski, Executive Vice President Salon F, 4 th Floor When communicating with physicians, we seek their perspectives only on data in the public domain.

MONDAY MARCH 6, 2017 - MeetMax Conference Agenda 3-4-17.pdfElizabeth Thiele, M.D., Ph.D., Director, Pediatric Epilepsy Program and Director, ... Shanshan Xu Orthopedics Massachusetts

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1 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017

Schedule Overview

7:00 AM – 5:45 PM Registration Atrium, 3rd Floor

7:00 AM – 8:00 AM Breakfast Buffet Salon E, 4th Floor

8:00 AM – 12:15 PM General Session and Topical Panels Salons F, G, H, 4th Floor

8:00 AM – 5:55 PM Private Company Presentations MIT, 3rd Floor

12:20 PM – 1:15 PM Lunch – Health Care Jeopardy! Welcome Remarks – Jeff Solomon President, Cowen Group

Salon E, 4th Floor

1:20 PM – 5:45 PM Public Company Presentations 1st, 2nd, 3rd and 4th Floors

6:00 PM – 7:00 PM Networking Reception Atrium, 3rd Floor

General Session

8:00 AM – 8:55 AM

Cowen Moderator: Chris Krueger

ACA Repeal/Replace and the 2017 GOP Healthcare Agenda Crossroads Strategies Mat Lapinski, Executive Vice President

Salon F, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

2 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Topical Workshops

Choose one of the following:

9:05 AM – 10:05 AM

Cowen Moderators: Phil Nadeau

Joe Thome

Marc Frahm

Ritu Baral

Alex Huynh

Seizure Disorders

Boston Children’s Hospital Jurriaan M. Peters, M.D., Ph.D., Director, Computational Neurophysiology,

Division of Epilepsy and Clinical Neurophysiology; Assistant Professor of

Neurology, Harvard Medical School

Massachusetts General Hospital Andrew Cole, M.D., Director, MGH Epilepsy Service; Professor of

Neurology, Harvard Medical School Massachusetts General Hospital

Elizabeth Thiele, M.D., Ph.D., Director, Pediatric Epilepsy Program and Director, Carol and James Herscot Center for Tuberous Sclerosis Complex; Professor of

Neurology, Harvard Medical School

Salon F, 4th Floor

9:05 AM – 10:05 AM

Cowen Moderators: Steve Scala

Kathy Miner

Luca Issi

Eric Schmidt

Chris Shibutani

Immune Oncology/Solid Tumors

Georgetown Lombardi Comprehensive Cancer Center

Michael B. Atkins, M.D., Deputy Director; William M. Scholl Professor and Vice-Chair, Department of Oncology and Professor of Medicine, Georgetown

University Medical Center

Yale Comprehensive Cancer Center

Roy S. Herbst, M.D., Ph.D., Chief of Medical Oncology, Director, Thoracic Oncology Research Program, Co-Director Developmental Therapeutics

Program and Associate Director for Translational Research; Ensign Professor of Medicine (Oncology) and Professor of Pharmacology, Yale School of Medicine

Salon G, 4th Floor

9:05 AM – 10:05 AM

Cowen Moderators: Josh Jennings

Shanshan Xu

Orthopedics

Massachusetts General Hospital

Harry Rubash, M.D., Emeritus Chief, Department of Orthopaedic Surgery; Hip and Knee Replacement Orthopaedic Surgeon; Edith M. Ashley Professor of

Orthopaedic Surgery, Harvard Medical School

New England Baptist Hospital

Daniel Ward, M.D., Hip and Knee Replacement Orthopaedic Surgeon;

Assistant Clinical Professor Department of Orthopaedic Surgery,

Tufts University School of Medicine

Salon H,

4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

3 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Topical Workshops

Choose one of the following:

10:10 AM – 11:10 AM

Cowen Moderators: Phil Nadeau

Marc Frahm

Steve Scala

Kathy Miner

Josh Jennings

Shanshan Xu

Rheumatology/Dermatology

Brigham and Women’s Hospital

Michael Weinblatt, M.D., Co-Director of Clinical Rheumatology; John R. and Eileen K. Riedman Professor of Medicine, Harvard Medical School

Massachusetts General Hospital/Harvard Medical School

Sarina Elmariah, M.D., Ph.D., Instructor in Dermatology, Cutaneous Biology Research Center, Department of Dermatology

Tufts Medical Center Jeffrey Sobell, M.D., Dermatologist; Dermatologist, Skin Care Physicians of

Chestnut Hill; Assistant Professor, Tufts University School of Medicine

Salon F, 4th Floor

10:10 AM – 11:10 AM

Cowen Moderators: Ritu Baral

Alex Huynh

Joe Thome

Ken Cacciatore

Bill Maughan

Luca Issi

Hemophilia Mount Sinai Hospital Christopher Walsh, M.D., Director, Hemophilia Program in the Division of Hematology and Medical Oncology; Associate Professor of Medicine,

Hematology and Medical Oncology, Mount Sinai School of Medicine

Oregon Health & Science University Jason A. Taylor, M.D., Ph.D., Associate Director, The Hemophilia Center and

Associate Professor, Hematology and Medical Oncology

Salon G,

4th Floor

10:10 AM – 11:10 AM

Cowen Moderators: Christine Arnold

Calvin Sternick

Benefits Consultant Panel: Strategies to Manage Drug and Medical Trends

Segal Consulting

Dean C. Hatfield, CEBS, Senior Vice President, Health Practice Leader

USI Insurance Services Michael Turpin, Executive Vice President

Salon H, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

4 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Topical Workshops

Choose one of the following:

11:15 AM – 12:15 PM

Cowen Moderators: Tyler Van Buren

Ken Cacciatore

Bill Maughan

Joe Thome

Luca Issi

Boris Peaker

Ophthalmology

Harvard Glaucoma Center of Excellence Louis R. Pasquale, M.D., Co-Director; Professor of Ophthalmology, Harvard

Medical School

New England Eye Center

Jay S. Duker, M.D., Director; Professor and Chairman, Department of

Ophthalmology, Tufts Medical Center, Tufts University School of Medicine

Tauber Eye Center

Joseph Tauber, M.D., Founder

Salon F, 4th Floor

11:15 AM – 12:15 PM

Cowen Moderators: Steve Scala

Phil Nadeau Kathy Miner

Chris Shibutani

Ritu Baral

Marc Frahm

Respiratory: Asthma, COPD, Cystic Fibrosis and Pulmonary Hypertension Boston Children’s Hospital

Gregory Sawicki, M.D., M.P.H., Director, Cystic Fibrosis Center; Assistant Professor of Pediatrics, Harvard Medical School

Tufts Medical Center Nicholas Hill, M.D., Chief, Pulmonary, Critical Care and Sleep Division;

Professor of Medicine, Tufts University School of Medicine

University of North Carolina Hospitals Pulmonary Specialty Clinic James Donohue, M.D., Emeritus Chief of the Division of Pulmonary and Critical Care; Professor of Medicine, University of North Carolina School of Medicine

Salon G,

4th Floor

11:15 AM – 12:15 PM

Cowen Moderator: Charles Rhyee

How Big Data Will Change The Way Your Doctor Sees You

Cleveland Clinic Peter Rasmussen, M.D., Medical Director, Distance Health; Associate

Professor of Neurological Surgery, Cleveland Clinic School of Medicine, Case

Western Reserve University

NantHealth

Vasu Rangadass, Ph.D., SVP and Chief Strategy Officer

Orion Health Ian McCrae, Chief Executive Officer

Vidyo

Eran Westman, President and Chief Executive Officer

Salon H,

4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

5 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

12:20 PM – 1:15 PM Lunch – Health Care Jeopardy! Welcome Remarks – Jeff Solomon, President, Cowen Group

Salon E,

4th Floor

6 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Public Company Presentations - 1:20 PM – 1:50 PM

Company Presentation Room Breakout Room

(2:00-2:30 PM)

ACADIA Pharmaceuticals Inc.

Stephen Davis, President & CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Acorda Therapeutics

Richard Batycky, Ph.D., Chief Technology Officer & Site Head

Ron Cohen, M.D., President & CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Alexion Pharmaceuticals David Brennan, Interim-CEO

Salon H, 4th Floor Salon K, 4th Floor

Aurinia Pharmaceuticals Richard Glickman, CEO

Orleans, 4th Floor Hyannis, 4th Floor

Bioverativ

John Cox, CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Bruker Corporation

Anthony Mattacchione, SVP & CFO

St. Botolph, 2nd Floor No Breakout

CytomX Therapeutics Sean McCarthy, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Dynavax Technologies Eddie Gray, President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

MyoKardia

Tassos Gianakakos, CEO Salon B, 4th Floor Salon A, 4th Floor

Nexvet Biopharma

Mark Heffernan, Ph.D., CEO

Salon C, 4th Floor Salon D, 4th Floor

Roche Holding LTD

Michael Varney, Ph.D., Head Genentech

Research and Early Development

Boylston, 1st Floor Columbus II, 1st Floor

Shire

Jeffrey Poulton, CFO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Stryker

Katherine Owen, VP Strategy & IR

Lonny Carpenter, Group President, Global

Quality & Operations

Tremont, 1st Floor Columbus I, 1st Floor

ViewRay

Chris Raanes, President & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

7 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Public Company Presentations – 2:00 PM- 2:30 PM

Company Presentation Room Breakout Room

(2:40-3:10 PM)

Acceleron Pharma

Habib Dable, President & CEO Salon B, 4th Floor Salon A, 4th Floor

Adamas Pharmaceuticals

Greg Went, Chairman & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Agios Pharmaceuticals David Schenkein, M.D., CEO

Provincetown, 4th Floor No Breakout

Baxter

Jay Saccaro, CFO Suffolk, 3rd Floor Wellesley, 3rd Floor

Bristol-Myers Squibb

Giovanni Caforio, CEO

Salon H, 4th Floor No Breakout

Cytokinetics Robert Blum, President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

Insulet

Michael Levitz, CFO

St. Botolph, 2nd Floor No Breakout

InVivo Therapeutics Holdings Corp

Mark Perrin, CEO Orleans, 4th Floor Hyannis, 4th Floor

Ironwood Pharmaceuticals

Tom Graney, CFO

Boylston, 1st Floor Columbus II, 1st Floor

NeuroDerm Oded Lieberman, Ph.D., CEO

Salon C, 4th Floor Salon D, 4th Floor

OvaScience

Christophe Couturier, CFO Harvard, 3rd Floor Brandeis, 3rd Floor

R1 RCM

Joe Flanagan, President & CEO Christopher Ricaurte, CFO & Treasurer

Vineyard, 4th Floor Yarmouth, 4th Floor

United Therapeutics Martine Rothblatt, CEO

Tremont, 1st Floor No Breakout

Vertex Pharmaceuticals

Ian Smith, EVP & COO

Simmons, 3rd Floor No Breakout

8 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Public Company Presentations - 2:40 PM – 3:10 PM

Company Presentation Room Breakout Room

(3:20-3:50 PM)

Accuray

Joshua Levine, President & CEO

Provincetown, 4th Floor No Breakout

Adverum Biotechnologies

Amber Salzman, President & CEO Regis, 3rd Floor Boston University, 3rd Floor

Alnylam Pharmaceuticals John Maraganore, CEO

Tremont, 1st Floor Columbus I, 1st Floor

AMAG Pharmaceuticals

Bill Heiden, CEO Nicholas Grund, EVP & Chief Commercial Officer

Simmons, 3rd Floor Tufts, 3rd Floor

Antares Pharma

Robert Apple, President & CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

AstraZeneca

David Berman, SVP, R&D Oncology IMED

Salon H, 4th Floor No Breakout

Cempra, Inc. David Moore, President & COO

Salon B, 4th Floor Salon A, 4th Floor

Concert Pharmaceuticals Roger Tung, President & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Curis

Ali Fattaey, President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Editas Medicine

Katrine Bosley, CEO

Boylston, 1st Floor Columbus II, 1st Floor

Horizon Pharma plc

Tim Walbert, Chairman, President & CEO

St. Botolph, 2nd Floor No Breakout

Ocular Therapeutix

Amar Sawhney, Ph.D., President, CEO &

Chairman of the Board

Vineyard, 4th Floor Yarmouth, 4th Floor

Pacira Pharmaceuticals

Jim Scibetta, President

Suffolk, 3rd Floor Wellesley, 3rd Floor

9 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Public Company Presentations - 3:20 PM – 3:50 PM

Company Presentation Room Breakout Room

(4:00-4:30 PM)

Axovant Sciences

Vivek Ramaswamy, CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Biogen

Michel Vounatsos, CEO

Salon H, 4th Floor No Breakout

Cascadian Therapeutics Scott Myers, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Centene Ed Kroll, SVP & CFO

Boylston, 1st Floor Columbus II, 1st Floor

CR Bard

Christopher Holland, Senior VP & CFO Tremont, 1st Floor No Breakout

Emergent BioSolutions Daniel Abdun-Nabi, President & CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Foamix Pharmaceuticals

David Domzalski, President

Salon C, 4th Floor Salon D, 4th Floor

Helius Medical Technologies

Phillipe Deschamps, President & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Oxford Immunotec Global PLC

Peter Wrighton-Smith, Ph.D., CEO

St. Botolph, 2nd Floor No Breakout

Puma Biotechnology Alan Auerbach, Chairman, CEO & President

Provincetown, 4th Floor Nantucket, 4th Floor

PureTech Health

Daphne Zohar, Founder & CEO Orleans, 4th Floor Hyannis, 4th Floor

Spark Therapeutics

Jeff Marrazzo, CEO Salon B, 4th Floor Salon A, 4th Floor

Syndax Pharmaceuticals

Briggs Morrison, M.D., CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

TiGenix

Eduardo Bravo, CEO

Regis, 3rd Floor Boston University, 3rd Floor

10 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Public Company Presentations - 4:00 PM – 4:30 PM

Company Presentation Room Breakout Room

(4:40-5:10 PM)

Aldeyra Therapeutics

Todd Brady, M.D., Ph.D., CEO Steve Tulipano, CFO

Orleans, 4th Floor Hyannis, 4th Floor

Ardelyx

Mike Raab, CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Corvus Pharmaceuticals

Richard Miller, M.D., President & CEO

Salon B, 4th Floor Salon A, 4th Floor

Dermira

Andrew Guggenhime, COO & CFO Thomas Wiggans, Founder & CEO

Boylston, 1st Floor Columbus II, 1st Floor

Hill-Rom Holdings John Greisch, President & CEO

Tremont, 1st Floor No Breakout

Histogenics

Adam Gridley, President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

Infinity Pharmaceuticals Adelene Perkins, CEO

Salon C, 4th Floor Salon D, 4th Floor

Inotek Pharmaceuticals David Southwell, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Invitae Corp

Sean George, Ph.D., CEO

St. Botolph, 2nd Floor Champion’s PDR, 2nd Floor

MacroGenics

Scott Koenig, M.D., Ph.D., President &

CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Merus B.V. John Crowley, EVP & CFO

Ton Logtenberg, Ph.D., CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Nabriva Colin Broom, CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Radius Health

Robert Ward, CEO Provincetown, 4th Floor Nantucket, 4th Floor

Zoetis

Clint Lewis, EVP & President, International

Operations

Salon H, 4th Floor Salon K, 4th Floor

11 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

Public Company Presentations - 4:40 PM – 5:10 PM

Company Presentation Room Breakout Room

(5:15-5:45 PM)

Aduro Biotech

Stephen Isaacs, Chairman, President & CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Aevi Genomics

Mike Cola, President & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Alimera Sciences Richard Eiswirth, President & CFO Dan Myers, CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Coherus Biosciences

Dennis Lanfear, President, CEO & Chairman

Suffolk, 3rd Floor No Breakout

Epizyme

Robert Bazemore, President & CEO Provincetown, 4th Floor No Breakout

Foundation Medicine Troy Cox, CEO

Steven Kafka, President & COO

St. Botolph, 2nd Floor No Breakout

Intercept Pharmaceuticals

Rachel McMinn, Ph.D., Chief Business and Strategy Officer

Tremont, 1st Floor Columbus I, 1st Floor

LeMaitre Vascular Dave Roberts, President

Orleans, 4th Floor Hyannis, 4th Floor

Lion Biotechnologies Maria Fardis, Ph.D., MBA, CEO

Boylston, 1st Floor Columbus II, 1st Floor

Ohr Pharmaceutical

Jason Slakter, M.D., CEO Regis, 3rd Floor Boston University, 3rd Floor

Pieris Pharmaceuticals

Stephen Yoder, President & CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Reata Pharmaceuticals

Colin Meyer, M.D., Chief Medical Officer &

VP of Product Development

Salon B, 4th Floor Salon A, 4th Floor

Voyager Therapeutics

Steven Paul, M.D., President & CEO

Salon C, 4th Floor Salon D, 4th Floor

12 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

MONDAY, MARCH 6, 2017 (Continued)

One-on-One Only Participating Companies

Public Companies Private Companies

PAREXEL International

Private Company Presentations – MIT, 3rd Floor

8:00 AM -

8:25 AM

Compass Therapeutics

Thomas Schuetz, CEO

1:00 PM -

1:25 PM

Adaptive Biotechnologies

Julie Rubinstein, Chief Business Officer

8:30 AM -

8:55 AM

Allena Pharmaceuticals Louis Brenner, M.D., COO

1:30 PM -

1:55 PM

Enterome Pierre Belichard, CEO

9:00 AM -

9:25 AM

ArmaGen Mathias Schmidt, Ph.D., CEO

2:00 PM -

2:25 PM

Innovate Biopharmaceuticals Steve Laumas, Director

Christopher Prior, Ph.D., CEO

9:30 AM -

9:55 AM

Moderna Therapeutics

Stephane Bancel, CEO

2:30 PM -

2:55 PM

Tarveda Therapeutics

Drew Fromkin, President & CEO

10:00 AM -

10:25 AM

Wuxi NextCODE

Hannes Smarason, COO

3:00 PM -

3:25 PM

Mersana Therapeutics

Anna Protopapas, President & CEO

10:30 AM -

10:55 AM

RaNA Therapeutics Ronald Renaud, CEO

3:30 PM -

3:55 PM

UroGen Ron Bentsur, CEO

11:00 AM -

11:25 AM

Warp Drive Bio

Laurence Reid, Ph.D., CEO

4:00 PM -

4:25 PM

Unum Therapeutics

Charles Wilson, President & CEO

11:30 AM -

11:55 AM

Chrono Therapeutic

Alan Levy, Ph.D., Chairman & CEO

4:30 PM -

4:55 PM

Aptinyx

Norbert G. Riedel, Ph.D., President & CEO

12:00 PM -

12:25 PM

TCR² Therapeutics

Garry Menzel, Ph.D., CEO

5:00 PM -

5:25 PM

Allakos

Christopher Bebbington, DPhil,

President & CEO

12:30 PM -

12:55 PM

Precision Biosciences

Abid Ansari, VP, Head of Finance

5:30 PM -

5:55 PM

OMNIlife Science

Rick Randall, CEO

6:00 PM – 7:00 PM Networking Reception – Atrium, 3rd Floor

13 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017

Schedule Overview

6:00 AM – 6:45 AM Back Bay 5K Run Atrium (registration desk), 3rd Floor

7:00 AM – 6:00 PM Registration Atrium, 3rd Floor

7:00 AM – 7:45 AM Breakfast with Cowen Health Care Analysts Med Tech Team Breakfast

Biotech Team Breakfast

Salon D, 4th Floor Gloucester, 3rd Floor

7:00 AM – 8:00 AM Breakfast Buffet Salon E, 4th Floor

8:00 AM – 12:30 PM Public Company Presentations 1st, 2nd, 3rd and 4th Floors

8:00 AM – 5:55 PM Private Company Presentations MIT, 3rd Floor

12:35 PM – 1:25 PM Lunch with Keynote Presentation Richard A. Moscicki, M.D. Deputy Center Director for Science Operations, U.S. Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research (CDER)

Salon E, 4th Floor

1:30 PM – 6:00 PM Topical Workshops Salons F, G, H, 4th Floor

6:30 PM – 10:00 PM All-Conference Evening Event Shuttle Buses Depart Marriott at 6:15 PM

Royale Boston, 279 Tremont St.

14 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentations - 8:00 AM – 8:30 AM

Company Presentation Room Breakout Room

(8:40-9:10 AM)

Alkermes

Richard Pops, Chairman & CEO

Simmons, 3rd Floor Tufts, 3rd Floor

argenx

Tim Van Hauwermeiren, MSc, EMBA, CEO

Tremont, 1st Floor Columbus I, 1st Floor

aTyr Pharma

John Mendlein, Ph.D., CEO & Director Orleans, 4th Floor Hyannis, 4th Floor

Boston Scientific

Daniel Brennan, EVP & CFO Susan Lisa, VP IR

Salon H, 4th Floor No Breakout

Camurus Fredrik Tiberg, President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Chimerix Inc

Garrett Nichols, Chief Medical Officer Regis, 3rd Floor Boston University, 3rd Floor

DexCom Matthew Dolan, Senior Director Corporate Affairs

St. Botolph, 2nd Floor No Breakout

Impax Laboratories

Kevin Buchi, Interim President & CEO Bryan Reasons, SVP & CFO

Suffolk, 3rd Floor Wellesley, 3rd Floor

KemPharm

Travis Mickle, Ph.D., President, CEO & Co-Founder

Vineyard, 4th Floor Yarmouth, 4th Floor

Neos Therapeutics

Vipin Garg, Ph.D., CEO, President & Director

Harvard, 3rd Floor Brandeis, 3rd Floor

SeaSpine

John Bostjancic, CFO

Keith Valentine, President & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

TransEnterix

Todd Pope, President & CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Ultragenyx Pharmaceutical Shalini Sharp, CFO

Boylston, 1st Floor Columbus II, 1st Floor

Vanda Pharmaceuticals Mihael Polymeropoulos, M.D., President &

CEO

Salon B, 4th Floor Salon A, 4th Floor

15 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentations - 8:40 AM – 9:10 AM

Company Presentation Room Breakout Room

(9:20-9:50 AM)

Allergan

Brenton Saunders, Chairman, CEO & President

Provincetown, 4th Floor Nantucket, 4th Floor

Bavarian Nordic

Seth Lewis, VP

Boylston, 1st Floor Columbus II, 1st Floor

bluebird bio Jeff Walsh, CFO & Chief Strategy Officer

Salon C, 4th Floor Salon D, 4th Floor

Eli Lilly and Company David Ricks, President & CEO

Salon H, 4th Floor Salon K, 4th Floor

Galapagos NV

Onno van de Stolpe, CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Global Blood Therapeutics Jeffrey Farrow, CFO Ted Love, M.D., President & CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Heron Therapeutics

Barry Quart, CEO Northeastern, 3rd Floor Gloucester, 3rd Floor

ImmunoGen, Inc. Mark Enyedy, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Immunomedics

Cynthia Sullivan, President & CEO Salon B, 4th Floor Salon A, 4th Floor

Median Technologies

Fredrik Brag, Chairman & CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Medtronic plc Geoffrey Martha, EVP & President,

Restorative Therapies Group

St. Botolph, 2nd Floor Falmouth, 4th Floor

miRagen Therapeutics

William Marshall, Ph.D., President & CEO Orleans, 4th Floor Hyannis, 4th Floor

NanoString Brad Gray, President & CEO

Tremont, 1st Floor Columbus I, 1st Floor

Otonomy

David Weber, Ph.D., CEO

Regis, 3rd Floor Boston University, 3rd Floor

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

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Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentations - 9:20 AM – 9:50 AM

Company Presentation Room Breakout Room (10:00-10:30 AM)

Achaogen

Kenneth Hillan, CEO Blake Wise, COO

Regis, 3rd Floor Boston University, 3rd Floor

Audentes Therapeutics

Matthew Patterson, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

BeiGene

John Oyler, Chairman, Founder & CEO

St. Botolph, 2nd Floor Falmouth, 4th Floor

Celldex Therapeutics

Anthony Marucci, President & CEO Thomas Davis, M.D., EVP & CMO

Orleans, 4th Floor Hyannis, 4th Floor

Fluidigm Chris Linthwaite, President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Innoviva, Inc.

Michael Aguiar, President & CEO

Boylston, 1st Floor Columbus II, 1st Floor

Intra-Cellular Therapies Sharon Mates, CEO

Tremont, 1st Floor No Breakout

Molecular Partners Patrick Amstutz, Ph.D., CEO

Andreas Emmenegger, CFO

Salon B, 4th Floor Salon A, 4th Floor

NantHealth

Robert Watson, President & Chief Growth Officer

Suffolk, 3rd Floor Wellesley, 3rd Floor

Nicox Gavin Spencer, EVP Corporate Development

Harvard, 3rd Floor Brandeis, 3rd Floor

Portola Pharmaceuticals

William Lis, CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Sanofi

Bill Sibold, Global Franchise Head Salon H, 4th Floor Salon K, 4th Floor

Savara Pharmaceuticals Rob Neville, CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

VWR Corp Greg Cowan, CFO

Provincetown, 4th Floor Nantucket, 4th Floor

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

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Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentations - 10:00 AM – 10:30 AM

Company Presentation Room Breakout Room (10:40-11:10 AM)

Aerie Pharmaceuticals

Vicente Anido, Jr., Ph.D., CEO & Chairman of the Board

Provincetown, 4th Floor Nantucket, 4th Floor

Bellerophon Therapeutics

Jonathan Peacock, Chairman of the Board

Fabian Tenenbaum, CEO

Salon B, 4th Floor Salon A, 4th Floor

Blueprint Medicines Jeff Albers, CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Capricor Linda Marban, Ph.D., CEO

Orleans, 4th Floor Hyannis, 4th Floor

ChemoCentryx Thomas Schall, CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

ConforMis

Mark Augusti, President & CEO

Paul Weiner, CFO

Harvard, 3rd Floor Brandeis, 3rd Floor

Illumina Marc Stapley, EVP & Chief Administrative

Officer

St. Botolph, 2nd Floor No Breakout

Novartis AG

James (Jay) Bradner, M.D., President, Novartis Institutes for BioMedical Research (NIBR)

Salon H, 4th Floor Salon K, 4th Floor

NuVasive

Micah Young, VP, Financial Planning &

Analysis Carol Cox, EVP, Corporate Marketing &

External Affairs

Simmons, 3rd Floor No Breakout

Regulus Therapeutics

Paul Grint, M.D., President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Revance Therapeutics

Dan Browne, Co-Founder, President & CEO

Boylston, 1st Floor Columbus II, 1st Floor

Vocera Communications Justin Spencer, CFO

Tremont, 1st Floor Columbus I, 1st Floor

Zafgen

Thomas Hughes, Ph.D., President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

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Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentations - 10:40 AM – 11:10 AM

Company Presentation Room Breakout Room (11:20-11:50 AM)

Adaptimmune Therapeutics

Gwendolyn Binder-Scholl, Ph.D., Chief Technology Officer

James Noble, CEO

Regis, 3rd Floor Boston University, 3rd Floor

Affimed

Florian Fischer, Ph.D., CFO Adi Hoess, M.D., Ph.D., CEO

Orleans, 4th Floor Hyannis, 4th Floor

Castlight Health Siobhan Nolan Mangini, CFO

Harvard, 3rd Floor Brandeis, 3rd Floor

Exelixis

Michael Morrissey, Ph.D., President & CEO

Salon H, 4th Floor Salon K, 4th Floor

Glycomimetics Rachel Smith, CEO

Salon C, 4th Floor Salon D, 4th Floor

Hologic

Robert McMahon, CFO

St. Botolph, 2nd Floor Falmouth, 4th Floor

Jounce Therapeutics

Richard Murray, Ph.D., CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Juno Therapeutics Hans Bishop, President & CEO

Boylston, 1st Floor Columbus II, 1st Floor

Minerva Biosciences

Geoff Race, EVP, CFO & CBO

Tremont, 1st Floor Columbus I, 1st Floor

Momenta Pharmaceuticals

Craig Wheeler, CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Myovant Sciences

Lynn Seely, M.D., President & CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Omeros Corporation Greg Demopulos, M.D., Chairman &

CEO

Simmons, 3rd Floor Tufts, 3rd Floor

OpGen

Evan Jones, Chairman & CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Versartis

Jay Shephard, CEO Salon B, 4th Floor Salon A, 4th Floor

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

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Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentations - 11:20 AM – 11:50 AM

Company Presentation Room Breakout Room (12:00-12:30 PM)

Aclaris Therapeutics

Dr. Neal Walker, President, CEO & Director

Harvard, 3rd Floor Brandeis, 3rd Floor

Arbutus Biopharma

Adam Cutler, SVP, Corporate Affairs Orleans, 4th Floor Hyannis, 4th Floor

BioMarin Pharmaceutical Dan Spiegelman, CFO

Boylston, 1st Floor Columbus II, 1st Floor

Genomic Health

Brad Cole, COO & CFO

St. Botolph, 2nd Floor No Breakout

Halozyme Therapeutics

Helen Torley, M.B., Ch.B., M.R.C.P., President & CEO

Athena Countouriotis, SVP & Chief Medical

Officer

Salon B, 4th Floor Salon A, 4th Floor

Insmed

Will Lewis, President & CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Kite Pharma David Chang, EVP, Research &

Development, Chief Medical Officer

Suffolk, 3rd Floor Wellesley, 3rd Floor

Nektar Therapeutics Stephen K. Doberstein, Ph.D., Chief

Scientific Officer & SVP

Salon C, 4th Floor Salon D, 4th Floor

Pfizer Inc.

John Young, Group President, Pfizer Essential Health

Salon H, 4th Floor Salon K, 4th Floor

Ra Pharmaceuticals, Inc.

Douglas Treco, Ph.D., President, CEO &

Co-Founder

Regis, 3rd Floor Boston University, 3rd Floor

TherapeuticsMD

Robert Finizio, CEO, Co-Founder & Director

Tremont, 1st Floor Columbus I, 1st Floor

Trillium Therapeutics Robert Uger, Ph.D., Chief Scientific Officer

Vineyard, 4th Floor Yarmouth, 4th Floor

XOMA

Jim Neal, CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Zimmer Biomet Holdings

Bob Marshall, VP, IR & Treasurer

Provincetown, 4th Floor No Breakout

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Public Company Presentation – 12:00 PM – 12:30 PM

Company Presentation Room Breakout Room

(12:40-1:10 PM)

Exact Sciences Kevin Conroy, Chairman of the Board,

CEO & President

St. Botolph, 2nd Floor No Breakout

One-on-One Only Participating Companies

Private Company Presentations – MIT, 3rd Floor

8:00 AM –

8:25 AM

Livongo Glen Tullman, CEO

1:30 PM –

1:55 PM

Sigmoid Pharma Ivan Coulter, Founder & CEO

8:30 AM –

8:55 AM

Bicycle Therapeutics Kevin Lee, CEO

2:00 PM –

2:25 PM

Nohla Therapeutics Colleen Delaney, Chief Medical Officer

9:00 AM –

9:25 AM

MISSION Therapeutics

Anker Lundemose, M.D., Ph.D., DMSc,

CEO

2:30 PM –

2:55 PM

Prolacta Bioscience

Scott Elster, CEO

9:30 AM –

9:55 AM

Spero Therapeutics

Ankit Mahadevia, M.D., President & CEO

3:00 PM –

3:25 PM

True North Therapeutics

Adam Rosenthal, Ph.D., Chief Business

Officer

10:00 AM –

10:25 AM

BioNTech

Sean Marett, COO

3:30 PM –

3:55 PM

PsiOxus

John Beadle, CEO

10:30 AM –

10:55 AM

Sienna Biopharmaceuticals

Frederick Beddingfield, President & CEO

4:00 PM –

4:25 PM

Twist Bioscience

Emily Leproust, Ph.D., CEO

11:00 AM –

11:25 AM

Bioventus

Tony Bihl, CEO

4:30 PM –

4:55 PM

Somalogic

Byron Hewett, CEO

11:30 AM –

11:55 AM

Genalyte Cary Gunn, Ph.D., President & CEO

5:00 PM –

5:25 PM

Immunocore Eva-Lotta Allan, CBO

12:00 PM –

12:25 PM

NuCana Hugh Griffith, CEO

Public Companies Public Companies Private Companies

bioMerieux Thermo Fisher Scientific Abpro

Johnson & Johnson Akili Interactive

Merck & Co. G1 Therapeutics

PerkinElmer Ovid Therapeutics

Sage Therapeutics Rebiotix

Swedish Orphan Biovitrum AB Singulex

The Medicines Company

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

12:35 PM – 1:25 PM Lunch with Keynote Presentation Richard A. Moscicki, M.D. Deputy Center Director for Science Operations, U.S. Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research (CDER))

Salon E,

4th Floor

Topical Workshops

Choose one of the following:

1:30 PM – 2:30 PM

Cowen Moderators: Steve Scala

Kathy Miner

Luca Issi

Ritu Baral

Chris Shibutani

Eric Schmidt

Cardiology/Diabetes

Audie L. Murphy Memorial VA Hospital Ralph A. DeFronzo, M.D., Deputy Director, Texas Diabetes Institute; Professor

of Medicine and Chief of the Diabetes Division, University of Texas Health Science Center

Brigham and Women’s Hospital Jorge Plutzky, M.D., Director, Preventive Cardiology; Associate Professor,

Harvard Medical School

Brigham and Women’s Hospital Scott D. Solomon, M.D., Director, Noninvasive Cardiology and Senior Physician; The Edward D. Frohlich Distinguished Chair Professor of

Medicine, Harvard Medical School; International Associate Editor, European Heart Journal

Salon F, 4th Floor

1:30 PM – 2:30 PM

Cowen Moderators: Doug Schenkel

Adam Wieschhaus

Genetics Tools for the Clinic and Research

Broad Institute of MIT and Harvard Stacey Gabriel, Ph.D., Senior Director, Genomics Platform

Dartmouth-Hitchcock Medical Center

Gregory J. Tsongalis, Ph.D., Director, Clinical Genomics and

Advanced Technology, Professor of Pathology and Laboratory Medicine, Geisel School of Medicine

Nationwide Children's Hospital

Elaine R. Mardis, Ph.D., Co-Director, Institute for Genomic Medicine;

Professor, Department of Pediatrics, Ohio State University College of Medicine

Salon G, 4th Floor

1:30 PM – 2:30 PM

Cowen Moderators: Charles Rhyee

Rick Weissenstein

Pharma and PBM Expert Debate: How To Move Towards Value-Based Drug Reimbursement

DAS Health Partners

David Schlett, Health Care Advisor & Finance Executive

Pharmaceutical Research and Manufacturers of America (PhRMA)

Lori M. Reilly, Executive Vice President for Policy, Research and Membership

Salon H, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Topical Workshops

Choose one of the following:

2:40 PM – 3:40 PM

Cowen Moderators: Doug Schenkel

Chris Lin

Ryan Blicker

Infectious Disease/Diagnostics

Massachusetts General Hospital Mary Jane Ferraro, Ph.D., MPH, Co-Director, Microbiology Laboratory;

Professor of Pathology and Professor of Medicine, Harvard Medical School

Medical College of Wisconsin

Nate Ledeboer, Ph.D., Medical Director, Clinical Microbiology and Molecular Diagnostics and Assistant Professor of Pathology

Salon F, 4th Floor

2:40 PM – 3:40 PM

Cowen Moderators: Josh Jennings

Shanshan Xu

Electrophysiology Boston Medical Center Kevin Monahan, M.D., Director Electrophysiology and Arrhythmia Center,

Associate Professor of Medicine, Boston University School of Medicine

Brigham and Women’s Hospital

Laurence M. Epstein, M.D., Chief, Cardiac Arrhythmia Service; Professor of Medicine, Harvard Medical School

Danbury Hospital

Robert Winslow, M.D., Director of Electrophysiology; Attending Electrophysiologist, Bridgeport Hospital; Staff Physician, Cardiac Specialists

Massachusetts General Hospital David Milan, M.D., Ph.D., Co-Director of the Cardiac Electrophysiology

Fellowship Program; Attending Electrophysiologist; Professor of Medicine, Harvard Medical School

Salon G,

4th Floor

2:40 PM – 3:40 PM

Cowen Moderators: Charles Rhyee

Rick Weissenstein

Pharma Perspective of the Republican Agenda For Drug Pricing

Independent Expert Consultant Charles Clapton, Former Senior Vice President, Federal Advocacy, Pharmaceutical Research and Manufacturers of America (PhRMA)

Salon H,

4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

23 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Topical Workshops

Choose one of the following:

3:50 PM – 4:50 PM

Cowen Moderators: Boris Peaker

Chris Shibutani

Steve Scala

Joe Catanzaro

Breast Cancer

Dana-Farber Cancer Institute & Brigham and Women’s Hospital Harold Burstein, M.D., Ph.D., Medical Oncologist, Breast Oncology Center;

Associate Professor of Medicine, Harvard Medical School

Dana-Farber Cancer Institute

Eric P. Winer, M.D., Senior Vice President and Chief Clinical Strategy Officer, Division of Women’s Cancers, Director, Breast Oncology Program, Susan F.

Smith Center for Women’s Cancers and Thompson Chair in Breast Cancer Research Institute Physician; Professor of Medicine, Harvard Medical School

Salon F, 4th Floor

3:50 PM – 4:50 PM

Cowen Moderators: Eric Schmidt

Ritu Baral

Jeff Chen

Alex Huynh

Kevin Patel

Marc Frahm

Orphan Neuromuscular Disorders (SMA, DMD and Pompe)

Boston Children’s Hospital Basil T. Darras, M.D., Associate Neurologist-in-Chief, Director, Neuromuscular Program and Director, Division of Clinical Neurology; Professor of Neurology,

Harvard Medical School University of Florida Health

Barry Byrne, M.D., Ph.D., Director, UF Powell Gene Therapy Center, Professor,

Pediatrics and Molecular Genetics & Microbiology and Associate Chair, Pediatrics

Salon G, 4th Floor

3:50 PM – 4:50 PM

Cowen Moderator: Charles Rhyee

Digital Therapeutics: What It Can Mean For Health Care

Akili Interactive Eddie Martucci, Chief Executive Officer

Proteus Digital Health Andrew Thompson, Co-Founder, President and Chief Executive Officer

WellDoc

Kevin McRaith, Chief Executive Officer

Salon H, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

24 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

TUESDAY, MARCH 7, 2017 (Continued)

Topical Workshops

Choose one of the following:

5:00 PM – 6:00 PM

Cowen Moderators: Eric Schmidt

Jeff Chen

Marc Frahm

Josh Jennings

Luca Issi

Joe Catanzaro

Hematologic Malignancies: ALL, AML and CLL

Dana-Farber Cancer Institute Matthew S. Davids, M.D., MMSc., Associate Director, CLL Center; Assistant

Professor of Medicine at Harvard Medical School

Dana-Farber Cancer Institute

Daniel J. DeAngelo, M.D., Ph.D., Director, Clinical and Translational Research; Associate Professor of Medicine, Harvard Medical School

Salon F, 4th Floor

5:00 PM – 6:00 PM

Cowen Moderators: Boris Peaker

Tyler Van Buren Ritu Baral

Alex Huynh

Pain Massachusetts General Hospital

Hany Bedair, M.D., Hip and Knee Replacement Orthopedic Surgeon; Assistant Professor of Orthopedic Surgery, Harvard Medical School

Naples Anesthesia and Pain Associates Group Joseph V. Pergolizzi, Jr., M.D., Senior Partner; Adjunct Assistant Professor,

Department of Medicine, Johns Hopkins University School of Medicine

St. Elizabeth's Medical Center

Andrew Sternlicht, M.D., Director, Anesthesiology Clinical Research; Assistant Professor, Anesthesiology and Pain Management, Tufts Medical School and St.

Elizabeth's Medical Center

Salon G,

4th Floor

5:00 PM – 6:00 PM

Pharma Policy Forecast From Drug Pricing to Repatriation Cowen Washington Research Group

Chris Krueger, Managing Director and Strategist

Cowen Washington Research Group

Rick Weissenstein, Managing Director

Prevision Policy

Michael McCaughan, Founding Member, FDA & Pharma

Salon H,

4th Floor

6:30 PM – 10:00 PM All-Conference Reception Dinnah – WICKED Boston Royale Boston, 279 Tremont Street Featuring Live Performances by Jason Cardinal and Along The Drive Shuttle Buses Depart Marriott at 6:15 PM

When communicating with physicians, we seek their perspectives only on data in the public domain.

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017

Schedule Overview

7:00 AM – 4:00 PM Registration Atrium, 3rd Floor

7:00 AM – 7:45 AM Breakfast with Cowen Health Care Analysts Health Care Services Team Breakfast Pharmaceutical Team Breakfast

Salon D, 4th Floor

Gloucester, 3rd Floor

7:00 AM – 8:00 AM Breakfast Buffet Salon E, 4th Floor

8:00 AM – 12:30 PM Public Company Presentations 1st, 2nd, 3rd and 4th Floors

8:00 AM – 4:25 PM Private Company Presentations MIT, 3rd Floor

12:35 PM – 1:25 PM Networking Lunch Buffet

Salon E, 4th Floor

1:30 PM – 4:50 PM Topical Workshops

Salons F, G, H, 4th Floor

26 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Public Company Presentations - 8:00 AM – 8:30 AM

Company Presentation Room Breakout Room

(8:40-9:10 PM)

Agilent Technologies

Didier Hirsch, CFO Mark Doak, President of the Agilent

CrossLab Group

St. Botolph, 2nd Floor No Breakout

Albireo Pharma

Ron Cooper, President & CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Basilea Pharmaceutica International

Ltd. Ronald Scott, CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Cytori Therapeutics Tiago Girao, VP Finance & CFO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Dicerna Pharmaceuticals

Douglas M. Fambrough, Ph.D., President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Ekso Bionics

Thomas Looby, President & CEO

Max Scheder-Bieschin, CFO

Orleans, 4th Floor Hyannis, 4th Floor

Eleven Biotherapeutics

Stephen Hurly, President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

Endocyte

Mike Sherman, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Flexion Therapeutics

Michael Clayman, CEO

Boylston, 1st Floor No Breakout

Ionis Pharmaceuticals

Beth Hougen, SVP Finance & CFO Wade Walke, VP, Corporate

Communications & IR

Tremont, 1st Floor Columbus I, 1st Floor

Lexicon Pharmaceuticals

Lonnel Coats, President & CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Madrigal Pharmaceuticals

Paul Friedman, M.D., Chairman & CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

PDL Biopharma John McLaughlin, President & CEO

Salon B, 4th Floor Salon A, 4th Floor

Sarepta Therapeutics Edward Kaye, CEO

Salon H, 4th Floor Salon K, 4th Floor

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Public Company Presentations - 8:40 AM – 9:10 AM

Company Presentation Room Breakout Room

(9:20-9:50 AM)

Ablynx

Edwin Moses, CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Aptose Biosciences

Gregory Chow, SVP & CFO William Rice, Ph.D., Chairman, President

& CEO

Orleans, 4th Floor Hyannis, 4th Floor

Celgene Corporation Michael Pehl, President, Global Hematology & Oncology

St. Botolph, 2nd Floor No Breakout

Chiasma

Mark Fitzpatrick, President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

Corindus Vascular Robotics

Mark Toland, CEO

Salon C, 4th Floor Salon D, 4th Floor

GlaxoSmithKline

Axel Hoos, SVP, Oncology R&D

Salon H, 4th Floor Salon K, 4th Floor

GW Pharmaceuticals Julian Gangoli, President, North America

Justin Gover, CEO

Boylston, 1st Floor Columbus II, 1st Floor

Immune Design Stephen Brady, EVP, Strategy & Finance Carlos Paya, President & CEO

Salon B, 4th Floor Salon A, 4th Floor

Intellia Therapeutics Nessan Bermingham, CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Jazz Pharmaceuticals

Matthew Young, EVP & CFO

Tremont, 1st Floor Columbus I, 1st Floor

Novelion Therapeutics

Mary Szela, CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Nuvectra Walter Berger, CFO & COO

Scott Drees, CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Santhera Pharmaceuticals

Todd Bazemore, COO

Simmons, 3rd Floor Tufts, 3rd Floor

Tonix Pharmaceutical Holdings Corp. Seth Lederman, Founder & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Public Company Presentations - 9:20 AM – 9:50 AM

Company Presentation Room Breakout Room (10:00-10:30 AM)

AbbVie

William Chase, EVP & CFO Scott Brun, VP, Corporate Strategy Office

Salon H, 4th Floor No Breakout

Alliqua BioMedical

David Johnson, CEO Brian Posner, CFO

Vineyard, 4th Floor Yarmouth, 4th Floor

Amicus Therapeutics

John Crowley, Chairman & CEO

Tremont, 1st Floor Columbus I, 1st Floor

Celyad Christian Homsy, CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Clearside Biomedical

Daniel White, President & CEO Salon B, 4th Floor Salon A, 4th Floor

Edge Therapeutics Brian Leuthner, President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Kura Oncology Troy Wilson, Ph.D., J.D., President &

CEO

Orleans, 4th Floor Hyannis, 4th Floor

NantKwest

Patrick Soon-Shiong, M.D., Chairman & CEO

Boylston, 1st Floor Columbus II, 1st Floor

Natera

Matthew Rabinowitz, Ph.D., CEO

Simmons, 3rd Floor Tufts, 3rd Floor

OncoCyte

William Annett, CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Resverlogix

Kenneth Lebioda, SVP Business &

Corporate Development

Suffolk, 3rd Floor Wellesley, 3rd Floor

Sangamo Therapeutics, Inc.

Sandy Macrae, M.B., Ch.B, Ph.D.,

President & CEO

Regis, 3rd Floor Boston University, 3rd Floor

Teva Pharmaceutical Industries

Marcelo E. Bigal, M.D., Ph.D., SVP, Head of Global Specialty Development

Mike Derkacz, SVP & Head of Global

CNS

St. Botolph, 2nd Floor No Breakout

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Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Public Company Presentations - 10:00 AM – 10:30 AM

Company Presentation Room Breakout Room (10:40-11:10 AM)

AcelRx Pharmaceuticals

Timothy E. Morris, CFO, Head of Business Development

Regis, 3rd Floor Boston University, 3rd Floor

Aimmune Therapeutics

Stephen Dilly, CEO

Provincetown, 4th Floor Nantucket, 4th Floor

Array BioPharma

Ron Squarer, CEO Boylston, 1st Floor Columbus II, 1st Floor

Calithera Biosciences Susan Molineaux, CEO

Orleans, 4th Floor Hyannis, 4th Floor

Cerus Obi Greenman, President & CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

GenMark Diagnostics

Hany Massarany, CEO

Tremont, 1st Floor Columbus I, 1st Floor

Genocea Biosciences

Jonathan Poole, CFO

Salon B, 4th Floor Salon A, 4th Floor

Incyte

Steven Stein, M.D., EVP, Chief Medical Officer

St. Botolph, 2nd Floor No Breakout

Keryx Biopharmaceuticals Greg Madison, CEO

Simmons, 3rd Floor Tufts, 3rd Floor

La Jolla Pharmaceutical

George Tidmarsh, CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

ProQR Therapeutics

Daniel de Boer, CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

uniQure N.V. Matthew Kapusta, CEO

Salon C, 4th Floor Salon D, 4th Floor

30 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Public Company Presentations - 10:40 AM – 11:10 AM

Company Presentation Room Breakout Room (11:20-11:50 AM)

Catabasis Pharmaceutical

Jill Milne, Ph.D., Co-Founder & CEO

Regis, 3rd Floor Boston University, 3rd Floor

Corbus Pharmaceuticals

Yuval Cohen, CEO

Salon C, 4th Floor Salon D, 4th Floor

Cytosorbents Kathleen Bloch, CFO

Orleans, 4th Floor Hyannis, 4th Floor

Erytech

Iman El-Hariry, Chief Medical Officer Eric Soyer, CFO & COO

Harvard, 3rd Floor Brandeis, 3rd Floor

Horizon Discovery Group Darrin M. Disley, Ph.D., CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Loxo Oncology Joshua Bilenker, M.D., CEO

Simmons, 3rd Floor Tufts, 3rd Floor

Quotient Ltd

Paul Cowan, Chairman & CEO Salon B, 4th Floor Salon A, 4th Floor

REGENXBIO Ken Mills,CEO

Boylston, 1st Floor Columbus II, 1st Floor

Seattle Genetics Eric Dobmeier, COO

Salon H, 4th Floor Salon K, 4th Floor

Sunesis Pharmaceuticals

Daniel Swisher, President & CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

Supernus Pharmaceuticals

Jack Khattar, CEO

Tremont, 1st Floor Columbus I, 1st Floor

Trevena Inc.

Maxine Gowen, Ph.D., President & CEO

Suffolk, 3rd Floor Wellesley, 3rd Floor

Vericel Corp

Nick Colangelo, CEO

Provincetown, 4th Floor Nantucket, 4th Floor

31 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Public Company Presentations - 11:20 AM – 11:50 AM

Company Presentation Room Breakout Room (12:00-12:30 PM)

Alexandria Real Estate Equities Thomas Andrews, EVP, Regional Market

Director

Salon H, 4th Floor Salon K, 4th Floor

Amgen

Tony Hooper, EVP, Global Commercial Operations

St. Botolph, 2nd Floor No Breakout

Avinger Matthew Ferguson, Chief Business Officer

& CFO Jeffrey Soinski, President & CEO

Tremont, 1st Floor Columbus I, 1st Floor

Biofrontera AG Hermann Lübbert, CEO

Harvard, 3rd Floor Brandeis, 3rd Floor

Idera Pharmaceuticals

Joanna Horobin, M.B., Ch.B., CMO Salon B, 4th Floor Salon A, 4th Floor

Ocera Therapeutics

Michael Byrnes, M.B.A., CFO Linda Grais, M.D., CEO

Regis, 3rd Floor Boston University, 3rd Floor

PhaseRx Robert Overell, Ph.D., President & CEO

Salon C, 4th Floor Salon D, 4th Floor

Recro Pharma

Gerri Henwood, CEO Provincetown, 4th Floor Nantucket, 4th Floor

Seres Therapeutics Roger J. Pomerantz, M.D., President,

CEO & Chairman

Suffolk, 3rd Floor Wellesley, 3rd Floor

Stemline Therapeutics

Ivan Bergstein, M.D., CEO

Northeastern, 3rd Floor Gloucester, 3rd Floor

Strongbridge Biopharma

Matthew Pauls, President & CEO Orleans, 4th Floor Hyannis, 4th Floor

Syros Pharmaceuticals Nancy Simonian, M.D., CEO

Vineyard, 4th Floor Yarmouth, 4th Floor

32 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

One-on-One Only Participating Companies

Public Companies Private Companies

EyeGate Pharmaceuticals GRAIL

MedAvail Technologies

Private Company Presentations – MIT, 3rd Floor

8:00 AM -

8:25 AM

Autolus

Christian Itin, Chairman & CEO

12:00 PM -

12:25 PM

Synlogic

JC Gutierrez-Ramos, Ph.D., CEO

8:30 AM -

8:55 AM

NGM Bio

Jeff Jonker, President

1:30 PM -

1:55 PM

Proclara Biosciences

Franz Hefti, Ph.D., President & CEO

9:00 AM -

9:25 AM

X4 Pharm Paula Ragan, Ph.D., CEO & President

2:00 PM -

2:25 PM

Atreca Tito Serafini, Ph.D., President, CEO, &

Founder

9:30 AM -

9:55 AM

Gritstone Oncology

Andrew Allen, CEO

2:30 PM -

2:55 PM

Frequency Therapeutics

David Lucchino, Co-Founder, President & CEO

10:00 AM -

10:25 AM

Arsanis

Mike Gray, CFO & CBO

3:00 PM -

3:25 PM

Codiak Biosciences

Douglas Williams, CEO

11:00 AM -

11:25 AM

Scholar Rock Elan Ezickson, COO

Nagesh Mahanthappa, Ph.D., CEO

3:30 PM-

3:55 PM

Aerpio Therapeutics Joseph Gardner, President & CEO

11:30 AM -

11:55 AM

Axcella Robert Connelly, President & CEO

4:00 PM-

4:25 PM

OptiNose Peter Miller, CEO

33 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

12:35 PM – 1:25 PM

Networking Lunch Buffet

Salon E, 4th Floor

Topical Workshops

Choose one of the following:

1:30 PM – 2:30 PM

Cowen Moderators: Marc Frahm

Eric Schmidt

Santhosh Palani

Jeff Chen

Boris Peaker

Doug Schenkel

CAR T Therapies and Cellular IO

Dana-Farber Cancer Institute Caron A. Jacobson, M.D., Physician, Hematologic Oncology; Instructor in Medicine, Harvard Medical School

Massachusetts General Hospital

Jeremy Abramson, M.D., Clinical Director, Lymphoma Program, Cancer Center; Assistant Professor of Medicine, Harvard Medical School

Moffitt Cancer Center Marco L. Davila, M.D., Ph.D., Associate Member, Department of Immunology

and Department of Blood and Marrow Transplantation

Salon F, 4th Floor

1:30 PM – 2:30 PM

Cowen Moderators: Ritu Baral

Tyler Van Buren

Ken Cacciatore

Chris Shibutani

Alex Huynh

Phil Nadeau

Neuropsych - Psychosis/Major Depression/Schizophrenia

University of Pennsylvania Michael Thase, M.D., Director and Professor of Psychiatry, Mood and Anxiety

Program, Perelman School of Medicine Yale University

Gerard Sanacora, M.D., Ph.D., Director and Professor of Psychiatry, Yale Depression Research Program, School of Medicine

Salon G, 4th Floor

1:30 PM – 2:30 PM

Cowen Moderators: Doug Schenkel

Ryan Blicker

Josh Jennings

Diabetes Devices

Integrated Diabetes Services, LLC

Gary Scheiner, M.S., CDE, Owner & Clinical Director

Joslin Diabetes Center Lori Laffel, M.D., M.P.H., Chief, Pediatric, Adolescent and Young Adult

Section; Professor of Pediatrics, Harvard Medical School

Salon H, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

34 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Topical Workshops

Choose one of the following:

2:40 PM – 3:40 PM

Cowen Moderators: Chris Shibutani

Santhosh Palani

Boris Peaker

Ken Cacciatore

Joe Thome

Gastrointestinal Diseases - IBS and IBD

Boston Medical Center Francis A. Farraye, M.D., Co-Director, Center for Digestive Disorders; Professor

of Medicine, Boston University School of Medicine

Dartmouth-Hitchcock Medical Center

Brian E. Lacy, M.D., Ph.D., Chief, Section of Gastroenterology and Hepatology; Professor of Medicine, Geisel School of Medicine, Dartmouth College

Salon F, 4th Floor

2:40 PM – 3:40 PM

Cowen Moderators: Ritu Baral

Tyler Van Buren

Phil Nadeau

Marc Frahm

Kevin Patel

Bill Maughan

NASH Mount Sinai Health System

Meena Bansal, M.D., Chief Medical Officer, Mount Sinai Care, LLC; Deputy Chief Medical Officer, Mount Sinai Health Partners; Associate Professor of

Medicine and Director of Translational Research, Liver Diseases, Icahn School of Medicine at Mount Sinai

Weill Cornell Medical College David E. Cohen, M.D., Ph.D., Chief, Division of Gastroenterology &

Hepatology and Vincent Astor Distinguished Professor of Medicine,

Joan & Sanford I. Weill Department of Medicine

Salon G, 4th Floor

2:40 PM – 3:40 PM

Cowen Moderators: Josh Jennings

Shanshan Xu

Cardiology – Structural Heart Beth Israel Deaconess Medical Center Jeffrey Popma, M.D., F.A.C.C., F.S.C.A.I., Director, Innovations in

Interventional Cardiology and Senior Attending Physician; Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital

Pinak Bipin Shah, M.D., Director of Cardiac Catheterization Lab; Assistant

Professor, Harvard Medical School

Massachusetts General Hospital

Ignacio Inglessis, M.D., Director, Adult Congenital Heart Disease Interventions

and Attending Interventional Cardiologist; Assistant Professor of Medicine,

Harvard Medical School

Salon H, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.

35 Follow us @CowenandCompany @CowenResearch Join the Twitter discussion #CowenHealthCare

Cowen and Company 37th Annual

Health Care Conference Boston Marriott Copley Place, Boston, MA

www.cowen.com

Conferences Agenda

WEDNESDAY, MARCH 8, 2017 (Continued)

Topical Workshops

Choose one of the following:

3:50 PM – 4:50 PM

Cowen Moderators: Ken Cacciatore

Tyler Van Buren

Bill Maughan

Phil Nadeau

Ritu Baral

Joe Thome

Parkinson’s, Huntington’s and Tardive Dyskinesia

Beth Israel Deaconess Medical Center Samuel Frank, M.D., Director, HDSA Center of Excellence; Associate

Professor of Neurology, Harvard Medical School

Parkinson’s Disease and Movement Disorders Center

Stuart Isaacson, M.D., Director; Associate Professor of Neurology, FIU Herbert Wertheim College of Medicine

Salon F, 4th Floor

3:50 PM – 4:50 PM

Cowen Moderators: Chris Shibutani

Santhosh Palani

Marc Frahm

Luca Issi

Joe Catanzaro

Tumor Microenvironment & Novel Targets in Immuno-Oncology

Georgia Cancer Center at Augusta University

Samir N. Khleif, M.D., GRA Distinguished Scientist and Clinician, Professor of Medicine, Professor of Biochemistry & Molecular Biology and Professor of

Graduate Studies University of Chicago Medicine

Jason J. Luke, M.D., FACP, Medical Oncologist and Assistant Professor of Medicine, Melanoma and Developmental Therapeutics Clinics

Salon G,

4th Floor

3:50 PM – 4:50 PM

Cowen Moderators: Josh Jennings

Shanshan Xu

Doug Schenkel

Hospital Executive Panel – Capital Budgets and Medical Device Pricing

Massachusetts General Hospital

Peter L. Slavin, M.D., President; Professor of Health Care Policy, Harvard Medical School

Salon H, 4th Floor

When communicating with physicians, we seek their perspectives only on data in the public domain.