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DRUG DOSES

The drug doses in the following pages are reproduced from the 15 th edion (2010)

of Drug Doses, courtesy of Professor Frank Shann, from the Intensive Care Unit,

Royal Childrens Hospital, Parkville, Victoria 3052, Australia

DRUGS ARE LISTED BY GENERIC NAME

1/100=1%=10mg/ml, 1/1000=1mg/ml, 1/10000=0.1mg/mlAbacavir.8mg/kg (adult 300mg) 12H oral.

Abacavir + lamivudine.600mg/300mg tab,

>12yr (NOT/kg): 1tab daily oral.

Abacavir + lamivudine + zidovudine.

300mg/150mg/300mg tab, 18yr (NOT/kg):

1tab 12H oral.

Abarelix. Adult (NOT/kg): 1 vial (delivers 100mg)

IM on day 1, 15 and 29, and then every 28 days.

Abatacept.NOT/kg: 500mg (40-60kg) 750mg(60-100 kg) 1g (>100kg) IV over 30min day 1,

2wk, 4wk, then every 4wk.

Abciximab.0.25mg/kg IV stat 10min before

angioplasty, then 0.2mcg/kg/min (max

10mcg/min) IV for 12hr.

Acamprosate calcium.Adult (NOT/kg). 60kg: 666mg 8H.

Acarbose.1-4mg/kg (adult 50-200mg) 8H oral.

Acebutolol. 4-8mg/kg (adult 200-400mg)

8-24H oral.

Aceclofenac.2mg/kg (adult 100mg) 12H oral.

Acemetacin. 1.2mg/kg (adult 60mg) 8-12H oral.

Acenocoumarol. See nicoumalone.

Acetaminophen. See paracetamol.

Acetazolamide.5-10mg/kg (adult 100-250mg)

6-8H (daily for epilepsy) oral.

Acetohydroxamic acid.5mg/kg (adult 250mg)

6-8H oral.Acetylcholine chloride. Adult (NOT/kg): 1% insl

0.5-2ml into anterior chamber of the eye.

Acetylcysteine.Paracetamol poisoning (regardless

of delay): 150mg/kg in 5%D IV over 1hr; then

10mg/kg/hr for 20hr (delay 16hr) and longer if sll

encephalopathic; oral 140mg/kg stat, then 70

mg/kg 4H for 72hr. Monitor serum K+.

Give if paracetamol >1000umol/L (150mg/L)

at 4hr, >500umol/L 8hr, >250umol/L 12hr.

Lung disease: 10% soltn 0.1ml/kg (adult 5ml)

6-12H nebulised or intratracheal.

Meconium ileus equivalent: 5ml (NOT/kg) of 20%

soltn 8H oral; 60-100ml of 50mg/ml for 45 min PR.

CF:4-8mg/kg 8H oral. Eye drop 5% + hypro-

mellose 0.35%: 1 drop/eye 6-8H.

Acetylsalicylic acid. See aspirin.

Acetyl sulfisoxazole.1.16g = 1.0g sulphafurazole (qv).

Aciclovir.Neonate - 12wk: 20mg/kg IV over 1hr

daily (12wk: EBV, herpes enceph,

immunodef, varicella: 500mg/m2 (12wk-12 yr)

10mg/kg (>12yr) 8H IV over 1hr. Cutaneous

herpes 250 mg/m2 (12wk-12yr) 5mg/kg (>12yr)

8H IV over 1hr. Genital herpes (>12yr NOT/kg):

200mg oral x5/day for 10 days, then 200mg

x2-3/day for 6mo if reqd. Zoster (>12yr NOT/kg):400 mg (=2yr) oral x5/day for

7 days. Cold sores: 5% cream x5/day.

Eye: 3% oint x5/day.

Acipimox.5mg/kg (adult 250mg) 8-12H oral.

Acitren.0.5-1mg/kg (adult 25-50mg) daily oral.

Acriflavine hydrochloride. 0.1% soltn: apply

12-24H.

Acrivasne. 0.15mg/kg (adult 8mg) 8H oral.

Acnomycin D.See dacnomycin.Acvated charcoal.See charcoal, acvated.

Adalimumab. Adult (NOT/kg): 40mg every 1-2wk SC.

Adapalene. 0.1% gel: apply once/day before bed

Adefovir. Adult (NOT/kg): 10mg daily oral.

Adenosine.Arrhythmia: 0.1mg/kg (adult 3mg)

stat by rapid IV push, incr by 0.1mg/kg (adult

3mg) every 2min to max 0.5 mg/kg (adult 18mg).

Pul hypertension: 50mcg/kg/min (3 mg/ml at

1ml/kg/hr) into central vein.

Adrenaline.Croup: 1% 0.05 ml/kg diluted to 4ml,

or 1/1000 0.5ml/kg (max 6ml) by inhaltn. Cardiac

arrest (repeat if reqd): 0.1ml/kg of 1/10,000 IV or

intracardiac; via ETT 0.1 ml/kg of 1/1000.

Anaphylaxis: IV 0.05-0.1ml/kg of 1/10,000, rpt

if reqd; IM into thigh: 0.01mg/kg (0.01ml/kg of

1/1000) up to 0.1mg/kg, x3 doses 20min apart

if reqd. IV infsn 0.3 mg/kg in 50ml 5%D-hep at

0.5-10ml/hr (0.05-1mcg/kg/min).

Adrenaline 0.1% +fl

uorouracil 3.33%.

Gel: inject into each wart x1/wk for up to 6wk.

Adrenocorcotrophic hormone (ACTH).See

corco-trophin.

Agalsidase beta.0.2-1mg/kg every 2wk IV over 40min

Agar + paraffin 65%.NOT/kg: 6mo-2yr 5ml,

3-5yr 5-10ml, >5yr 10ml 8-24H oral.

Agar + paraffin + phenolphthalein (Agarol).NOT/kg:

6mo-2yr 2.5ml, 3-5yr 2.5-5ml, >5yr 5ml 8-24H oral.

DrugDoses