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Name: ____________________________ Date: __________________
Mitosis and Asexual Reproduction – Chapter 5
5.1 The Cell Cycle and Mitosis Due to the loss and death of cells ______________________________. How many cells in your body?
• 50-100 million trillion• Every minute your body produces about __________________________________
Three stages in the cell cycle:
1. ____________________: cell carries out normal functions.
2. _______________________: nucleus contents duplicated and divided into two equal parts.
3. _____________________________: separation of two nuclei and cell contents into two daughter cells.
Parts of the Cell Cycle
Interphase Interphase - the _____________________ cell cycle stage (lasts 15 hrs. – months).
• cell performs normal functions and grows. In late interphase, DNA copies itself in the process of _______________________.
__________________________________ involves several steps:
• The DNA molecule ______________ with the help of an _______________.
• New bases pair with the bases on the
______________________ DNA.
• Two new identical DNA molecules are produced.
Now, ___________________the amount of DNA in nucleus _______________________
Late Interphase continued _________________________ is in its ______________________________ form so that DNA can be
copied into ________________ for proteins to be made in preparation for cell division.
At the end of interphase, the cell _________________________________________ and make proteins in preparation for mitosis and cytokinesis.
Chromosomes As the nucleus prepares to divide, replicated DNA in interphase joins
to form _________________________________ joined by a
__________________________.
Mitosis Overview: Mitosis is the shortest stage of the cell cycle where the ________________,
___________________ and two _________________________________ are formed.
It occurs in 4 stages: 1. ___________________________________
2. ___________________________________
3. ___________________________________
4. ___________________________________ Helpful saying to remember the order:
“I picked many apples today.”
Mitosis - Prophase Chromosomes start to coil and become
________________________.
Pairs of _________________________ start to separate.
The ________________________________ disappears.
____________________________________ start to form between the centriole pairs.
Chromosomes move more evenly throughout the nucleus.
Mitosis - Metaphase Centriole pairs move to ____________________________ of
the cell.
Spindle fibers are still attached to the centriole pairs.
Chromosomes _____________________________________
____________________ of the cell and are attached to the spindle fibers.
Mitosis - Anaphase The pair of ____________________________________
at the centromere and move to opposite ends of the spindle.
Now there are ______________________ the number of chromosomes within the cell membrane.
Movement of the chromosomes towards the opposite ends
of the cell membrane is aided by the _________________
____________________________________.
Mitosis - Telophase Nuclear membranes form around the
__________________________________ of chromosomes.
The spindle fiber disappears.
Chromosomes start to uncoil (____________________) and become less visible.
Cell starts to make a groove (_____________________) in the middle to eventually split into two identical cells.
Cytokinesis The division of material ___________ of the nucleus.
Occurs after ______________________.
Divides the organelles and other substances in the cytoplasm into roughly two equal halves.
Animal cells furrow while plant cells form a _____
_____________
# chromosomes in daughter cell _______________ the # chromosomes in parent cell.
Daughter cells are ____________________________ to parent.
Cell Cycle Problems Checkpoints in the cell cycle will prevent cell division if:
1. If the cell is short of _________________________________
2. If the DNA within the nucleus has _________________________________________
3. If the _________________________________________________________
Mutations in genes involving checkpoints can result in an out-of-control cell cycle. The result can be
uncontrolled cell division: _________________________________
• Cancer cells have __________________________________________
• Cancer cells are not specialized, so they _____________________________
• Cancer cells attract blood vessels and grow into _____________________.
• Cells from tumours can break away to other areas of the body