Upload
lee-hutchinson
View
222
Download
0
Embed Size (px)
Citation preview
Mrs. Anna Ward
James Martin MS
March 29, 2012
1. How many males are present?2. How many females are present?3. How many generations?4. How many children does the first generation
(I) couple have?5. How many marriages are represented?6. How many males have the disease?7. How many females have the disease?
DO NOW!!!In the Pedigree to the Right, tell me….
Don’t forget Pass Expectations
Schedule for today:9:15 - 10:15 Cougar Time10:20 - 11:20 2nd Period11:25 - 12:55: 3rd Period
12:20 - 12:50 Lunch1:00 - 1:55 4th Period2:00 - 3:00 5th Period3:05 - 4:15 CELEBRATION! (Johnson &
Rodriguez's Room)
Announcements
Huntington’s Disease
Sickle Cell Anemia
Hemophilia
Create your own PEDIGREE
Agenda
Huntington's disease is a genetic disorder passed down through families in which nerve cells in certain parts of the brain waste away, or degenerate.
Huntington’s Disease
If one of your parents has it, you have a 50% chance of getting it.
Onset of the symptoms usually starts around age 40.
One of the common traits marked in pedigrees
First Genetic Disease Mapped to a Chromosome (#4)
Huntington’s Disease
http://www.youtube.com/watch?v=65xf1olEpQM
Huntington’s Disease
Why do you think it would be important to use a Pedigree to track Huntington’s Disease???
What do you notice about this Pedigree?
Huntington’s Disease
Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal crescent shape. (Red blood cells are normally shaped like a disc.)
http://www.youtube.com/watch?v=iKQmQHh4E2w&feature=related
http://www.youtube.com/watch?v=qe59ar-GZmg
SICKLE CELL DISEASE
Sickle Cell Pedigree:HOW IS THIS DIFFERENT FROM THE
PEDIGREE FOR HUNTINGTONS?
SICKLE CELL DISEASE
Hemophilia refers to a group of bleeding disorders in which it takes a long time for the blood to clot.
Known as the “ROYAL DISEASE” from the infamous Russian Royal Family
HEMOPHILIA
http://player.discoveryeducation.com/index.cfm?guidAssetId=A6AC1338-DEC9-4AA1-AEED-18BCAE0239DB&blnFromSearch=1&productcode=US
HEMOPHILIA
Royal Family Pedigree
Think of a trait that some (but not all) of your family members carry.
Some examples may be:Left-HandednessCurly HairTongue RollingWidow’s PeakAttached EarlobesFrecklesAllegiesCleft Chin…….
CREATE YOUR OWN PEDIGREE
Begin By Drawing your family members, using a
CIRCLE—Women/girlsSQUARE—Men/BoysDO NOT SHADE ANYTHING AT THIS POINT
Here is a diagram to help you remember how to draw one:
SECOND STEP…
If anyone is deceased, Make a diagonal slash mark through their circle or square.
Then use a Marker to Color in any family member with the trait.
If you do not know the trait for sure, you can take it home and complete it over the weekend.
THIRD STEP
Label your pedigree with your name, your family name
Place a “key” at the bottom or side indicating what each shape means.
FOURTH STEP